Updated 2-Site Intradermal Schedule

Day of Immunization Day 0 Day 3 Day 7 Day 28/30

PVRV/ PCEV 0.1 ml 0.1 ml 0.1 ml 0.1 ml

Site of Injection

Left and right deltoids or anterolateral thighs in infants Left and right deltoids or anterolateral thighs in infants Left and right deltoids or anterolateral thighs in infants Left and right deltoids or anterolateral thighs in infants

Computation and Dosage of Rabies Immune Globulin

HRIG at 20 IU/kg. body weight (150 IU/ml) 50 kg. patient x 20 IU/kg = 1000 IU 1000 IU 150 ml = 6.7 ml

ERIG/ F(ab)2 at 40 IU/kg. body weight (200 IU/ml) 50 kg. patient x 40 IU/kg = 2000 IU 2000 IU 200 IU/ml = 10 ml

Delay in day 3 dose: If delay is 1-2 days from day 3 schedule- give day 3 dose upon visit and follow the original schedule of day 7 and 28/30. If delay is 3-4 days from day 3 schedule- give day 3 dose upon visit, adjust succeeding doses (day 7 and 28/30) according to the prescribed interval. If delay is > 4 days from day 3 schedule- restart a new course. Delay in day 7 dose: If delay is < 7 days from day 7 schedule- give day 7 dose upon visit, give day 28/30 dose as originally scheduled. If delay is > 7-14 days from day 7 schedule- repeat day 3 dose and revise according to the prescribed interval. If delay is > 14 days from day 7 schedule- restart a new course. Delay in day 28/30 dose: Give day 28/30 upon visit; this may be considered as a booster. If RIG has already been administered, it should not be given again.