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  • Lung Cancer

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    David Hosam
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    1. Lung cancer epidemiology shows a 3:1 male to female ratio and accounts for 1/4 of cancer deaths, with 90% directly related to smoking. 2. Risk factors include asbestos, chromium, radiation, and arsenic. Symptoms are cough, blood in sputum, shortness of breath, chest pain, and recurrent pneumonia. 3. Small cell lung cancer makes up 20% of cases and responds well to chemotherapy but has a low 5-year survival rate of 3%. Non-small cell lung cancer is more common at 80% and radiation can help palliatively.

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    1. Lung cancer epidemiology shows a 3:1 male to female ratio and accounts for 1/4 of cancer deaths, with 90% directly related to smoking. 2. Risk factors include asbestos, chromium, radiation, and arsenic. Symptoms are cough, blood in sputum, shortness of breath, chest pain, and recurrent pneumonia. 3. Small cell lung cancer makes up 20% of cases and responds well to chemotherapy but has a low 5-year survival rate of 3%. Non-small cell lung cancer is more common at 80% and radiation can help palliatively.

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    10 views1 page

    Lung Cancer

    Uploaded by

    David Hosam
    1. Lung cancer epidemiology shows a 3:1 male to female ratio and accounts for 1/4 of cancer deaths, with 90% directly related to smoking. 2. Risk factors include asbestos, chromium, radiation, and arsenic. Symptoms are cough, blood in sputum, shortness of breath, chest pain, and recurrent pneumonia. 3. Small cell lung cancer makes up 20% of cases and responds well to chemotherapy but has a low 5-year survival rate of 3%. Non-small cell lung cancer is more common at 80% and radiation can help palliatively.

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    M:F 3:1 Epidemiology 1/4 of cancer deaths 90% directly related to smoking Risk Factors Asbestos, chromium, radiation,

    arsenic Cough, haemoptysis, dyspnoea, chest pain, recurrent pneumonia, weight loss Symptoms Swollen end of finger Increased curvature of nail Loss of normal angle Increased nail bed fluctuation Bronichial carcinoma Fibrosing alveolitis Liver cirrhosis Inflammatory bowel disease Endocarditis Differentials Signs Cachexia, anaemia, clubbing Signs

    Bronchial Carcinoma
    Complications

    Local: laryngeal nerve palsy, SVC obstruction, Horner's syndrome Metastatic: brain, bone, liver, adrenals Endocrine: ectopic hormone secretion (ADH, ACTH) Advanced at presentation

    Clubbing

    Lung Cancer
    Small Cell (20%)

    Excellent response to chemo 5 year survival 3% Most linked to smoking 20% patients suitable for surgery Non Small Cell (80%) Radiation is useful palliatively

    Infective (esp. TB) Neoplastic Sarcoidosis Pulmonary HT Traumatic Affordable

    Differentials of Haemoptysis Screening Requirements

    Deliverable Acceptable to target population Low false positive rate (reducing unnecessary interventions) Existence of an effective intervention

    Lung Cancer.mmap - 07/09/2010 -

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