Name of Drug Generic Name: Tramadol Brand Name: Dolcet

Classification of Drug Therapeutic: Analgesic (centrally acting) Pharmacologic: Opioid analgesic

Mechanism of Action Binds to muopioid receptors. Inhibits reuptake of serotonin and norepinephrine in the CNS. Therapeutic Effects: Decrease pain.

Indication Treatment of Relief of moderate to moderately severe pain

Contraindications Contraindicated with allergy to tramadol or opioids or acute intoxication with alcohol, opioids, or psychoactive drugs Use cautiously with pregnancy, lactation; seizures; concomitant use of CNS depressants, MAOIs, SSRIs, TCAs, renal impairment; hepatic impairment

Side Effects CNS: Sedation, dizziness or vertigo, headache, confusion, dreaming, sweating, anxiety, seizures CV: Hypotension, tachycardia, bradycardia Dermatologic: Sweating, pruritus, rash, pallor, urticaria GI: Nausea, vomiting, dry mouth, constipation, flatulence Other: Potential for abuse, anaphylactoid reactions

Nursing Responsibilities Control environment (temperature, lighting) if sweating or CNS effects occur o Warning Limit use in patients or present history of addiction to or dependence on opioids You may experience these side effects: Dizziness, sedation, drowsiness, impaired visual acuity (avoid driving or task that require alertness); nausea, loss of appetite (lie quietly, eat frequent small meals) Report severe nausea, dizziness, severe constipation