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    Aan Wardani
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    This study characterized blood pressure, prevalence of hypertension, and risk factors for hypertension in 1,332 children with chronic kidney disease enrolled in the Chronic Kidney Disease in Children cohort study. The researchers found that 15% of subjects had systolic hypertension, 11.5% had pre-hypertension, and 15% had diastolic hypertension, with 3.5% having pre-hypertension. Overall, 35% of subjects had elevated blood pressure or a history of hypertension plus current antihypertensive use. Characteristics associated with elevated blood pressure included black race, shorter duration of chronic kidney disease, absence of antihypertensive medication use, and elevated serum potassium. Among subjects receiving antihypertensive treatment, uncontrolled blood

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    This study characterized blood pressure, prevalence of hypertension, and risk factors for hypertension in 1,332 children with chronic kidney disease enrolled in the Chronic Kidney Disease in Children cohort study. The researchers found that 15% of subjects had systolic hypertension, 11.5% had pre-hypertension, and 15% had diastolic hypertension, with 3.5% having pre-hypertension. Overall, 35% of subjects had elevated blood pressure or a history of hypertension plus current antihypertensive use. Characteristics associated with elevated blood pressure included black race, shorter duration of chronic kidney disease, absence of antihypertensive medication use, and elevated serum potassium. Among subjects receiving antihypertensive treatment, uncontrolled blood

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    7 views1 page

    Blood Pressure in Children With Chronic Kidney Disease

    Uploaded by

    Aan Wardani
    This study characterized blood pressure, prevalence of hypertension, and risk factors for hypertension in 1,332 children with chronic kidney disease enrolled in the Chronic Kidney Disease in Children cohort study. The researchers found that 15% of subjects had systolic hypertension, 11.5% had pre-hypertension, and 15% had diastolic hypertension, with 3.5% having pre-hypertension. Overall, 35% of subjects had elevated blood pressure or a history of hypertension plus current antihypertensive use. Characteristics associated with elevated blood pressure included black race, shorter duration of chronic kidney disease, absence of antihypertensive medication use, and elevated serum potassium. Among subjects receiving antihypertensive treatment, uncontrolled blood

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    Blood Pressure in Children with Chronic Kidney Disease: AReport from the Chronic Kidney Disease in Children Study

    Joseph T Flynn1, ar! itsnefes2, Christopher Pierce3, Ste"en R Cole3, Rulan S Pare!h4, Susan # Furth4, Bradley A $arady5, and for the CKiD Study %roup6
    1Children's 2Children's

    Hospital and Regional Medical Center, Seattle, WA Hospital Medical Center, Cincinnati, OH 3Johns Hopkins Uni ersit! School o" #$%lic Health, &alti'ore, M( )Johns Hopkins Uni ersit! School o" Medicine, &alti'ore, M( *Children's Merc! Hospital, +ansas Cit!, MO

    A&stract
    ,o characteri-e the distri%$tion o" %lood press$re .&#/, pre alence and risk "actors "or h!pertension in pediatric chronic kidne! disease .C+(/, 0e cond$cted a cross1sectional anal!sis o" %aseline &#'s in )32 children .'ean age 11!2 345 'ale2 'ean glo'er$lar "iltration rate 678R9)) 'l:'in:1;<3'2/ enrolled in the Chronic +idne! (isease in Children cohort st$d!; &#'s 0ere o%tained $sing an aneroid sph!g'o'ano'eter; 78R 0as 'eas$red %! iohe=ol disappearance; >le ated &# 0as de"ined as &#?4th percentile "or age, gender and height; H!pertension 0as de"ined as &#?*th percentile or as sel"1reported h!pertension pl$s c$rrent treat'ent 0ith antih!pertensi e 'edications; 8or s!stolic &#, 1)5 0ere h!pertensi e and 115 0ere pre1h!pertensi e .&# ?41?* th percentile/23@5 o" s$%Aects 0ith ele ated S&# 0ere taking antih!pertensi e 'edications; 8or diastolic &#,1)5 0ere h!pertensi e, and ?5 0ere pre1h!pertensi e2 *35 o" s$%Aects 0ith ele ated (&# 0eretaking antih!pertensi e 'edications; *)5 o" s$%Aects had either s!stolic or diastolic &#?*thpercentile or a histor! o" h!pertension pl$s c$rrent antih!pertensi e $se; Characteristics associated 0ith ele ated &# incl$ded %lack race, shorter d$ration o" C+(, a%senceo" antih!pertensi e 'edication $se, and ele ated ser$' potassi$'; A'ong s$%Aects recei ingantih!pertensi e treat'ent, $ncontrolled &# 0as associated 0ith 'ale se=, shorter C+( d$rationand a%sence o" AC> inhi%itor or AR& $se; 3<5 o" children 0ith C+( had either ele ated s!stolic or diastolic &#, and 3?5 o" these 0ere notrecei ing antih!pertensi es, indicating that h!pertension in pediatric C+( 'a! %e "reB$entl! $nder1 or e en $n1treated; ,reat'ent 0ith AC> inhi%itors or AR&'s 'a! i'pro e &# control in these patients;

    Keywords kidne! disease2 children2 adolescents2 h!pertension2 %lood press$re2 AC> inhi%itors

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