Scribd Logo
Upload

Welcome to Scribd!

  • PUD Pathophysiology

    Uploaded by

    Kitty Panerio Domaoal-Cabarteja
    153 views1 page
    Helicobacter pylori infection, NSAID use, smoking, alcohol, diet, and stress can damage the gastric mucosal barrier and increase acid production, leading to further destruction of blood vessels and loss of plasma proteins. This results in ulceration, bleeding, and edema of the gastric mucosa. Predisposing factors like older age, male gender, genetics, and blood type further increase the risk of ulcer development.

    Original Description:

    :)

    Copyright

    © © All Rights Reserved

    Available Formats

    DOC, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Helicobacter pylori infection, NSAID use, smoking, alcohol, diet, and stress can damage the gastric mucosal barrier and increase acid production, leading to further destruction of blood vessels and loss of plasma proteins. This results in ulceration, bleeding, and edema of the gastric mucosa. Predisposing factors like older age, male gender, genetics, and blood type further increase the risk of ulcer development.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    153 views1 page

    PUD Pathophysiology

    Uploaded by

    Kitty Panerio Domaoal-Cabarteja
    Helicobacter pylori infection, NSAID use, smoking, alcohol, diet, and stress can damage the gastric mucosal barrier and increase acid production, leading to further destruction of blood vessels and loss of plasma proteins. This results in ulceration, bleeding, and edema of the gastric mucosa. Predisposing factors like older age, male gender, genetics, and blood type further increase the risk of ulcer development.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    PATHOPHYSIOLOGY

    Precipitating Factors:
    Helicobacter pylori
    NSAIDS
    Smoking
    Alcohol
    Diet (irritating foods) `
    Stress
    Destruction of mucosal
    cells
    Breakdown of gastric
    mucosa barrier
    Increased vagal
    activity
    arietal cell
    hy!er!lasia
    Predisposing Factors"
    Age
    #ender
    #enetics
    Blood ty!e $
    %ore &'l acid and !e!sin are
    released
    Destruction of blood
    vessels
    (oss of !lasma !roteins into gastric
    lumen
    Im!aired duodenal bicarbonate
    secretion
    )urther mucosal Decreased blood
    Bleeding
    &istamine
    release
    Increased
    vasodilation
    Increased ca!illary
    !ermeability
    %ucosal edema
    *lceration
    Bleeding *lceratio
    n
    %ucosal
    edema
    &y!ersecretion of&'l acid and
    !e!esin
    Acid back di+usion into the
    mucosa

    You might also like