NAME DRUG ACTION Special Precautions

CONTRAINDICATIONS NURSING INTERVENTION

Generic: Ranitidine


Brand: Zantac



Classification: Anti-ulcer
Mechanism of Action:

Inhibits the action of histamine at
the H2 receptor site located
primarily in gastric parietal cells,
resulting in inhibition of gastric
acid secretion
has some antibacterial action
against H. pylori





Pregnancy
Lactation (excreted in breast
milk)
Geriatric patients (more
susceptible to adverse CNS
reactions)
Renal impairments
Cirrhosis
Hypersensitivity, Cross-
sensitivity may occur; some
oral liquids contain alcohol
and should be avoided in
patients with known
intolerance

Instruct patient not to take new
medication w/o consulting physician
Instruct patient to take as directed and
do not increase dose
Allow 1 hour between any other antacid
and ranitidine
Avoid excessive alcohol
Assess patient for epigastric or
abdominal pain and frank or occult
blood in the stool, emesis, or gastric
aspirate
Nurse should know that it may cause
false-positive results for urine protein;
test with sulfosalicylic acid
Inform patient that it may cause
drowsiness or dizziness
Inform patient that increased fluid and
fiber intake may minimize constipation
Advise patient to report onset of black,
tarry stools; fever, sore throat; diarrhea;
dizziness; rash; confusion; or
hallucinations to health car professional
promptly
Inform patient that medication may
temporarily cause stools and tongue to
appear gray black
Instruct patients to monitor for and
report occurrence of drug-induced
adverse reaction

Mode of Administration Indications Adverse Effects Drug Interactions

Route: Oral


Dosage: 50mg


Timing:OD
Treatment and prevention of
heartburn, acid indigestion, and
sour stomach.
Prophylaxis of GI hemorrhage from
stress ulceration