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  • Ref - Lr. Bharat

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    Daniel Padilla
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    This letter recommends Mr. D. Bharat Kumar Reddy for funding from the CDMRP's Breast Cancer Research Program. It details that Mr. Reddy identified a natural compound from Terminalia chebula with COX-2 and 5-LOX inhibitor activities that exhibits anti-inflammatory and anti-cancer effects. The compound was characterized and these findings were published. The letter also states that Mr. Reddy is well-trained in relevant techniques and highly motivated to pursue academic research in anti-inflammatory and anti-cancer drug discovery.

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    Ref.lr. Bharat

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    This letter recommends Mr. D. Bharat Kumar Reddy for funding from the CDMRP's Breast Cancer Research Program. It details that Mr. Reddy identified a natural compound from Terminalia chebula with COX-2 and 5-LOX inhibitor activities that exhibits anti-inflammatory and anti-cancer effects. The compound was characterized and these findings were published. The letter also states that Mr. Reddy is well-trained in relevant techniques and highly motivated to pursue academic research in anti-inflammatory and anti-cancer drug discovery.

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    11 views1 page

    Ref - Lr. Bharat

    Uploaded by

    Daniel Padilla
    This letter recommends Mr. D. Bharat Kumar Reddy for funding from the CDMRP's Breast Cancer Research Program. It details that Mr. Reddy identified a natural compound from Terminalia chebula with COX-2 and 5-LOX inhibitor activities that exhibits anti-inflammatory and anti-cancer effects. The compound was characterized and these findings were published. The letter also states that Mr. Reddy is well-trained in relevant techniques and highly motivated to pursue academic research in anti-inflammatory and anti-cancer drug discovery.

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    of 1

    Prof. P.

    Reddanna Tel: +91-040-23010745 (O)


    Eicosanoids, Inflammation &
    Cancer Research Group Fax: +91-040-23010120
    Department of Animal Sciences E-mail: preddanna@yahoo.com
    School of Life Sciences prsl@uohyd.ernet.in
    University of Hyderabad
    Hyderabad-500 046, INDIA
    UNIVERSITY OF HYDERABAD

    To whom it may concern 02-12-09


    This letter is written in support of the application of Mr.D.Bharat Kumar Reddy
    for funding under CDMRP's Breast Cancer Research Program. Mr.Bharat joined my lab for
    PhD after qualifying in a nation-wide entrance test conducted by CSIR and UGC. Initially he
    was responsible for the development of assay methods for cyclooxygenases (COXs) and
    lipoxygenases (LOXs) compatible for ELISA and HTS. Employing these methods thousands of
    compounds have been screened for identifying specific COX and LOX inhibitors from natural
    and synthetic sources. As part of this program he identified a natural antioxidant from
    Terminalia chebula with COX-2/5-LOX dual inhibitor activities. The compound was isolated
    and characterized by LC-MS, MALDI-TOF, IR, NMR studies. This well characterized
    compound was shown to exhibit anti-inflammatory and anti-cancer activities in vitro and in vivo.
    These findings were published in reputed international journals and also a patent has been filed.

    Mr. Bharat is well trained in basic biochemical, molecular biology,


    chromatographic and cell culture techniques. He is exposed to the entire spectrum of pre-clinical
    drug discovery. He is extremely good in planning and execution of laboratory experiments, data
    analysis and manuscript writing. He has good written and communication skills in English.

    Mr. Bharat is a sincere student and highly motivated to pursue academic research. I
    really enjoyed working with him all these days. With his background and expertise in anti-
    inflammatory and anti-cancer drug discovery, Mr.Bharat will be able to handle the project on
    breast cancer successfully. I strongly recommend the proposal of Dr.Bharat for funding under
    CDMRP's Breast Cancer Research Program.

    (Prof.P.Reddanna)

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