Curriculum Vitae Balaram Ghosh, PhD

Prof. Balaram Ghosh, PhD Previous position

Epigenetic Research Laboratory Postdoctoral Research Fellow

Department of Pharmacy Center for Human Genetic Research

BITS-Pilani at Hyderabad campus & Center for System Biology

Harvard Medical School, Harvard University
Hyderabad, India 500 078
185 Cambridge Street, Boston, MA 02114
Phone: 91-9866941923(cell), 91-4066303639 (off)
Phone. 617-643-5444 (office)
E-mail:balaram@hyderabad.bits-pilani.ac.in,
E-mail: ghosh@chgr.mgh.harvard.edu

Link: http://universe.bits-pilani.ac.in/Hyderabad/balaram/Profile

Date of Birth: 16/03/1973

Place of Birth: West Bengal, India

Academic Qualifications
 Postdoctoral Research: Center for Human Genetic Research and Center for System Biology, Harvard Medical
School, Harvard University, Boston, Massachusetts, USA. 11/2009-08/2013
 PhD, Pharmaceutical Sciences, Wayne State University, Detroit, Michigan, USA. 2009. Over all GPA 3.63/4
 Master of Pharmacy (MS), Pharmaceutical Sciences, Jadavpur University, Kolkata, India, 2000. Marks. 76.2 %.
 Bachelor of Pharmacy (BS), Jadavpur University, Kolkata, India, 1998. Marks. 74.6 %.

Awards/Honors:
 Recipient of Research Excellence Award 2020 from Institute of Scholar
 Outstanding Scientist Award 2016 for the contribution and achievement in the field of Pharmaceutical Science:
Venus International Foundation – Center for Advanced Research and Design.
 “Frank O. Taylor” BEST GRADUATE STUDENT AWARD 2008, awarded by the department of Pharmaceutical
sciences, Wayne State University for the outstanding performance in research and graduate studies.
 Graduate Research Assistantship, Wayne State University (2005-2009)
 Junior Research Fellowship, University Grants Commissions, New Delhi, India for MS studies (1998-2000)
 National scholarship award, Govt. of West Bengal for higher studies (1990-1992).
 Curriculum Vitae Balaram Ghosh, PhD
Positions / Employments:
 01/06/2021 – present: Associate Professor, BITS-Pilani at Hyderabad campus, Hyderabad, India
 09/2013-31/05/2021: Assistant Professor, BITS-Pilani at Hyderabad campus, Hyderabad, India
 11/2009-08/2013: Postdoctoral Research Fellow, Center for Human Genetic Research and Center for System
Biology, Harvard Medical School, Harvard University, Boston, Massachusetts, USA.
 11/2009-08/2013: Associate Researcher at Broad Institute of Harvard and MIT, Cambridge, MA, USA
 08/2005-09/2009: Graduate Research Assistant (PhD Program), Wayne State University, Detroit, Michigan.
 04/2004-05/2005: Project Fellow; UGC sponsored project at Jadavpur University
 03/2000-04/2004: Teaching Faculty (Lecturer) at Himalayan Pharmacy Institute, Rangpo, Sikkim affiliated to North
Bengal University, West Bengal, India
 08/1998-03/2000: Junior Research Fellow, studied Master of Pharmacy (M.Pharm) in Pharmaceutical Chemistry.

Professional Activity:
Editorial Board Member and Reviewer:
 European Journal of Medicinal Chemistry
 European Journal of Pharmaceutical Sciences
 European Polymer Journal
 Journal of Biomolecular Structure & Dynamics
 Reactive and Functional Materials
 Journal of Hazardous Material
 Journal of Ethno Pharmacology
 Drug Delivery Science and Technology
 Bioorganic Chemistry
 Journal of Molecular Science
 Chemical Science
 European Journal of Pharmaceutics and Biopharmaceutics
 Expert Opinion On Biological Therapy
 International Journal of Pharmaceutics
 RSC ChemMedChem
 Drug Delivery
 Biomaterial Science
 Materials Science and Engineering C

Invited Speaker:
4. Resource Person: Learning and Memory: Yes we can enhance it AICTE sponsored Short Term Training Programme
(STTP) held from 18th January – 23rd January 2021 at Columbia Institute of Pharmacy, Raipur, India
3. Invited speaker: “Poly(caprolactone)-based polymeric micelles for the delivery of a histone deacetylase inhibitor as
anticancer therapy” 2nd Annual World Congress of Smart Materials-2016 (WCSM-2016) March 4 – 6, 2016, Singapore. My
work has been accepted to present under focus 502: Smart Materials for Pharmacy and Drug Delivery.
2. Key note speaker: “Global Prospect of Pharmaceutical Sciences” in the “Tech Festival valorous 2015” held on 9 th April
2015 at MLR institute of Pharmacy, Dundigal, Qutbhullapur, RR district, Hyderabad 500 043
 Curriculum Vitae Balaram Ghosh, PhD
1. Chief Resource personnel: AICTE Sponsored National Seminar on “Prospects and Perspective of Pharmacognosy in
India” held on 25th November 2013 at in Maharashtra College of Pharmacy, Nilanga, India.

Area of Research:
Our research is involved in exploring and understanding biological systems at the molecular level with a tool set
offered by modern chemistry. We work in the interface of organic chemistry and cell biology and manipulation of
cellular activity with bio-active molecules.
We believe that not only discovery of right bioactive molecules but also delivery of the molecules to the particular site
of action is equally challenging.
 Our major focus includes:
 Development of subtype specific histone deacetylase (HDAC) inhibitors/activators as epigenetic modulators mainly
potent and isoform selective HDAC inhibitors with fairly acceptable blood brain barrier permeability to understand the
individual isoform of HDAC responsible to turn on or turn off the transcription machineries involved with the genes
responsible for the improvement of cognition, memory and mood stabilization of patients suffering from depression and
dementia.
 Exploration of epigenetic modulators as the emerging treatment strategy to combat different forms of cancer
 Discovery of promising drug candidates for the treatment of cancer in collaboration with different drug discovery
researchers.
 Development of biocompatible polymeric drug delivery cargo with the help of polymer chemistry to bring the drugs at
the site of action with less off target effects in collaboration with different drug delivery experts.

Ongoing Sponsored Projects:

7. Funding Agency: DBT-BUILDER (Boost to University Interdisciplinary Life Science Departments for
Education and Research). Government of India
Fund amount: Recommended Rs. 300.00 Lakhs
Tittle of the Project: Interdisciplinary Life Science Programme for Advanced Research and Education
Duration: 2021 (3yrs) (Team Leader and PI)

6. Funding Agency: Council of Scientific and Industrial Research (CSIR) Government of India
Fund amount: Rs. 25.00 Lakhs (Approx)
Tittle of the Project: Development of Cost-effective, Electrophilic Trifluoromethylating Reagents and Their
Application to the Syntheses of New Classes of Medicinally Potential Trifluoromethylated
Heterocycles
Duration: 2021 (3yrs) (Co-PI)

5. Funding Agency: Council of Scientific and Industrial Research (CSIR) Government of India
Fund amount: Rs. 29.58 Lakhs (Approx)
Tittle of the Project: Bifunctional Gene-Expression Modulating Chemotherapeutic Agents as Improved
Treatment Strategy for Cancer
Duration: 2019 (3yrs) (PI)

4. Funding Agency:
Fund amount:
Tittle of the Project:
Department of Science and Technology, Government of India (DST-SERB, EMR
Funding: EMR/2016/001411)
Rs. 29.87 Lakhs
Design, Synthesis and Biological Evaluation of HDAC3 Selective Inhibitors as Long Term
Memory Enhancers
 Curriculum Vitae Balaram Ghosh, PhD
Duration: 2017 (3yrs) (PI)

3. Funding agency. Department of Science and Technology, Government of India (DST-SERB, FILENO.
CRG/20l8/001065.
Fund amount: Rs. 30.72 Lakh
Title of the project: Near-Infrared Light Degradable Nanomicellar Chemo-Photodynamic Therapy using
Aerobic Chlorin e6 Conjugate for Oropharyngeal Carcinomas
Duration: 2019-2022 (Co-PI)

2. Funding agency. Indian Council of Medical Research (ICMR), Govt. of India

Fund amount: Recommended 25 Lakhs (Approx.)
Title of the project: Functional role of histone deacetylase 6 (HDAC6) in the progression of oral squamous
cell carcinoma: regulation of IL-1 beta expression, autophagy and epithelial-
mesenchymal –transition (EMT).
Duration: 2019-Approved. (Co-PI)

1. Funding agency. Dr. Reddy’s Laboratory (DRL), Hyderabad

Fund amount: Rs. 8.01 Lakh
Title of the project: Formulation development and physico-chemical/in vitro/in vivo characterization of a
nano-suspension formulation of an anticancer drug.
Duration: 2018-2020 (PI-joint)

Completed Sponsored Projects:

6. Funding agency: SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (SPARC), India.
Fund amount: Rs. 29 Lakh
Title of the project: Chemically modified targeted anticancer drug
Duration: 2016- 2018 (PI-joint)

5. Funding agency: Daewoong Pharmaceuticals, Seoul, Republic of Korea

Fund amount: Rs. 22 Lakh
Title of the project: Development for sustained release injectable formulations
Duration: 2015-2017(PI-joint)

4. Funding agency: Department of Biotechnology, Government of India.

Fund amount: Rs. 37 Lakh
Title of the project: Cell penetrating peptide octa-arginine anchored, multifunctional poly(amidoamine)
dendrimer to promote delivery of chemotherapeutics in cancer.
Duration: 2014-2017 (Co-PI)

3. Funding agency: Birla Institute of Technology and Science-Pilani

(Additional Competitive Research Grant).
Fund amount: Rs. 9 Lakh
 Curriculum Vitae Balaram Ghosh, PhD
Title of the project: Design and Development of Isoform Selective HDAC3 Inhibitors for the Enhancement of
Long-term Memory.
Duration: 2015-2017 (PI)

2. Funding agency. Department of Science and Technology, Government of India

(Indo-Belarus joint proposal).
Fund amount: Rs. 10 Lakh
Title of the project: Tumor targeted nanomedicines for photodynamic therapy.
Duration: 2015-2017 (Co-PI)

1. Funding agency: Birla Institute of Technology and Science-Pilani at Hyderabad Campus (Research
Initiation Grant)
Fund amount: Rs. 2 Lakh
Title of the project: Development of Cognitive Enhancers that Inhibit Histone Deacetylase Activity and
Modulate Chromatin-mediated Neuroplasticity.
Duration: 2013-2015 (PI)

Completed: PhD Student

1. Prakruti Trivedi [ID: 2013PHXP415H; CSIR - SRF] [Supervisor]
Thesis Title: Project: Design, Synthesis and Biological Characterization of Isoform Selective Histone Deacetylase
(HDAC) Inhibitors
2. Himanshu Bhat (ID: 2015PHXP013H; CSIR-SRF) [Co-supervisor]
Thesis Title: Dendrimers for the Targeted Delivery of Chemotherapeutic Agents in Cancer 
3. Yamini Bobde (ID: 2016PHXF0424H; SUN PHARMA Fellow) [Supervisor]
Thesis Title: Development of Acrylate Polymer-Based Micellar Systems for the Delivery of Anticancer Drugs.  
 
PhD Students currently working (Supervisor)
1. Routholla Ganesh
DST-SERB sponsored project
Project: Synthesis of Small Molecule Inhibitors of Histone Deacetylase -3
2. Sravani Pulya
CSIR-SRF
Project: Development of Isoform Selective Histone Deacetylase Inhibitors
3. Tarun Kumar Patel
CSIR-EMR project
Project Title: Gene Expression Modulating Agents for the Treatment of Cancer
 
 PhD Students currently working (Co-supervisor)
1. Kumbham Sonya (ID: 2018PHXF0038H)
Dr. Reddy’s Lab Project [PI: Prof. Swati Biswas]
2. Yogesh Mahadu Khetmalis (ID: 2019PHXF0015H)
 Curriculum Vitae Balaram Ghosh, PhD
Title: Design, Synthesis and Biological Activity of Novel Heterocyclic Compounds as Anticancer and Anti-tubercular
agents. [PI: Prof. K.V.G. Chandra Sekhar]
3. Ashutosh Babasaheb Mahale (ID: 2019PHXF0048H)
Title: Functional role of histone deacetylase 6 (HDAC6) in the progression of oral squamous cell carcinoma. [PI: Prof.
Onkar P Kulkarni]
 
Thesis Students (FD & HD):
1. Sonali Kotagir [HD_ID No: 2012H147061H] [Winter 2014]
Project: Design and Development of Novel Histone Deacetylase-3 (HDAC3) Inhibitors using Molecular Modeling Studies
(Current position: USA)
2. Srividya Bharathi Bhagavatula [FD_ID: 2015A5TS0863H] [Winter 2019]
Project: Synthesis of Anticancer Agents
3. Gajraj Singh Rathore [FD_ID: 2015A5TS0869H] [Winter 2019]
Project: Exploring Mechanisms to Identify Response to Immune Checkpoint Inhibitors (Current position: University of
Geneva, Switzerland)
4. Shilpa Elsa George [FD_ID:2016A5TS0738H] [Fall 2019]
Project: Spectroscopic Characterization of Nano-particle Molecule Interactions (Current position: University of Colorado,
USA)
5. Tania Dutta [FD_ID:2016A5TS0748H] [Fall 2019]
Project: Epigenetic Regulation of NF-??B in Cancer
6. Shivani Paritosh Naik [FD_ID:2016A5TS0729H] [Fall 2019]
Project: Tumor Stroma Penetrating Nanoparticles for Combination Therapy of Drug Resistant Kidney Cancer (Current
position: University of New York, USA)
7. Nikhil Baheti (FD_ID: 2016A5TS0735H) [Winter 2020]
Project: Operations and Management of Pharmaceutical Products
8. Chaiti Chatterjee (FD_ID: 2016A5TS0728H) [Fall 2020]
Project: Value creation in mergers & acquisitions deals involving pharmaceutical industries in India and the subsequent
response of the consumers.
9. Kondapaneni Likhitha Purna (HD_ID: 2019H1460148H) [Winter 2021]
Project: Development of Dual pH Sensitive HPMA Conjugated Polymeric System for Effective Delivery of Doxorubicin

Patents (Approved/Filed):
17.  Human serum albumin nanoparticles system for redox-sensitive oxaliplatin prodrug delivery in cancer: Swati
Biswas, Balaram Ghosh, Milan Paul: Patent Authority BITS-Pilani: Indian Patent Application submitted, June 2021.
(New)
16. Polymeric amphiphilic nano-micelles for aerobic chemo-photodynamic therapy and method of preparing same: Swati
Biswas, Balaram Ghosh, Milan Paul: Patent Authority BITS-Pilani: Indian Patent Application number 202111032226.
Filed June 23, 2021. (New)
15. Hydrazide based HDAC3 selective inhibitors Balaram Ghosh, Swati Biswas, Sravani Pulya, Ganesh Routholla, Tarun
Kumar Patel. Patent Authority BITS-Pilani: Indian Patent Application Number 202111022553, Filed on May 20, 2021.
(New)
14. Benzamide Based HDAC3 Selective Inhibitors: Balaram Ghosh, Swati Biswas, Ganesh Routholla, Sravani Pulya;
Patent Authority BITS-Pilani: Indian Patent Application Number 202011056177. Filed on 23/12/2020 
13. 3-(1H-Indol-3-yl)-1,3-diphenyl propane-1-one derivatives as anticancer agents and a process of synthesis thereof:
Shovanlal Gayen, Umesh Kumar Patil, Kalpataru Das, Balaram Ghosh, Dipayan Mondal, Patent authority: Dr. Harisingh
 Curriculum Vitae Balaram Ghosh, PhD
Gour University, Sagar University, MP. Indian Patent Application Number 202021014498, Filed on 1st April, 2020.
Published 09.10.2020. 
12. 3-(3-oxoaryl) indoles as anti-cancer agents and a process of synthesis thereof: Shovanlal Gayen, Umesh Kumar
Patel, Kalpataru Das, Balaram Ghosh, Tarun Patel, Ruchi Gaikwad. Patent authority: Dr. Harisingh Gour
University, Sagar University, MP. Indian Patent Application Number 202021014497, Filed on 1st April, 2020. Published
09.10.2020
11. A muco-adhesive polymeric micellar structure and process for preparing the same: Swati Biswas, Balaram Ghosh,
Himanshu Bhat, Sanhita Roy: Patent authority: BITS-Pilani, Hyderabad Campus; Indian Patent Application Number.
201911034570 filed on 27th August, 2019.
10. Novel rhodamine B amides and processes for preparing the same: Jayanty Subbalakshmi, B. Himabindu, Balaram
Ghosh, Yamini Bobde. BITS-Pilani, Hyderabad Campus. Indian Patent Application Number 2019110220063; Filed on
21/05/2019.
9. Compounds for use as anticancer agents and a process for synthesizing the same: Jayanty Subbalakshmi, SD
Anwarhussaini, Balaram Ghosh, Yamini Bobde: Patent authority: BITS-Pilani, Hyderabad Campus Filed on 22
January 2019: Indian patent application Number 201941002679. Published 24.07.2020
8. Drug Delivery System Having HSA-DOPE Conjugated Micelles: Swati Biswas, Balaram Ghosh, Preeti Kumari, Yamini
Bobde. Patent authority. BITS-Pilani, Hyderabad Campus, Indian Patent Application Number 201811045804, Filed
on December 4, 2018. Published 12.06.2020
7. Compositions and Methods for Human Epigenetic Disorders: Stephen J. Haggarty, Wen-Ning Zhao, Balaram
Ghosh, Angela She, Ralph Mazitschek. File US Patent on June 2018
6. A hydrophilic redox-responsive polymeric micelle comprising Chlorin e6 for photodynamic therapy: Swati
Biswas, Balaram Ghosh, Preeti Kumari; Patent authority. BITS-Pilani, Hyderabad Campus Indian Patent Application
number 201711038735; Filed on Oct 2017. Published 21/06/19.Granted on 05/04/2021. Patent# 364102
5. A chemotherapeutic composition for treating malignant tumors and method for preparing the same: Swati
Biswas, Balaram Ghosh, Rompicharla Sri Vishnu Kiran, Trivedi Prakruti. Patent authority. BITS-Pilani, Hyderabad
Campus. Indian Patent Application number 201711028012; Filed on August 7, 2017. Published 08.02.2019
4. A nanomicellar Composition for Drug Delivery and Method of preparing the same. Inventors: Swati Biswas, Balaram
Ghosh, Omkara Swami Muddineti. Patent authority. BITS-Pilani, Hyderabad Campus. Indian Patent Application
number 201711016379; Filed on: May 9, 2017. Published 16.11.2018
3. Photo Switchable HDAC Inhibitors and Application of the same: Mazitschek, Ralph; Ghosh, Balaram, Haggarty,
Stephen J, Hendricks, James Adam, Reis, Surya A: European Patent EP14774678.8A   Published: 2016-01-20
2. Inhibitors of Histone Deacetylase: Ralph Mazitschek, Teru Hideshima, Kenneth C. Anderson, Stephen J.
Haggarty, Balaram Ghosh: Application number PCT/US2014/064016. Publication number WO2015069693A1
1. Photo Switchable HDAC Inhibitors: Mazitschek, Ralph; Ghosh, Balaram, Haggarty, Stephen J, Hendricks, James
Adam, Reis, Surya A: Application number PCT/US2014/026069. Publication number WO2014160221A

Book Chapters: 
7. Epigenetics of Memory Processes: Sravani Pulya and Balaram Ghosh* Hand Book of Epigenetics, 3rd Edition: Edited
by Prof. Trygve Tollefsbol: Elsevier; 2021: Submitted (New)
6. Exogenous Stimuli-responsive Polymeric Micelles for Drug Delivery: Likhitha Purna Kondapaneni, Yamini Bobde
and Balaram Ghosh* in a book titles as Polymeric micelles for drug delivery: Elsevier; 2021: Submitted (New)
5. Stimuli-responsive Nanomedicine for Treating Non-Cancer Diseases: Book titled as Stimuli-Responsive
Nanomedicine:  Himanshu Bhatt#, Balaram Ghosh#, and Swati Biswas: Published July 31 (2020) by Jenny Stanford
Publishing (CRC Press). ISBN 978-981-4800-70-9 (Hardcover), 978-0-429-29529-4 (eBook) [ # equal contribution]
4. Histone deacetylase 3 and its inhibitors: Sk. Abdul Amin, Nilanjan Adhikari,  Balaram Ghosh, Tarun Jha, for the
book:Advances in Medicine and Biology: NOVA SCIENCE PUBLISHERS, INN (July 2019)
3. Environmental Responsive Polysaccharide Nanocarrier for Controlled Drug Delivery: Yamini S Bobde and Balaram
Ghosh: in polysaccharide based nano-biocarrier in drug delivery-CRC Press (Taylor & Francis Group): 2018: ISBN: 13:
978-1-138-48111-4
 Curriculum Vitae Balaram Ghosh, PhD
2. Chlordecone, Monograph to the book, Encyclopedia of Toxicology, 3 rd Edition. Publisher. Elsevier. Swati
Biswas, Balaram Ghosh.
1. Chrysene. Monograph to the book, Encyclopedia of Toxicology, 3 rd Edition. Publisher. Elsevier. Balaram Ghosh, Swati
Biswas.

Publications (peer reviewed Journals)

 * Corresponding author; Average impact factor = 4.874; IF= Impact Factor JCR -2020, h-index= 28, citation= 3222
GoogleScholar: https://scholar.google.com/citations?hl=en&user=Ky-M-zcAAAAJ

2021…………….
102. Quantitative activity-activity relationship (QAAR) driven design to develop hydroxamate derivatives of pentanoic
acids as selective HDAC8 inhibitors: Synthesis, biological evaluation and binding mode of interaction studies: Sk. Abdul
Amin, Prakruti Trivedi, Nilanjan Adhikari, Routholla Ganesh, Dhanya Vijayasarathi, Sanjib Das, Balaram Ghosh, Tarun
Jha (Under Review: in New Journal of Chemistry)
101. Polymeric micelles of a copolymer composed of all-trans-retinoic acid, methoxy-poly(ethylene glycol), and b-poly(N-
(2 hydroxypropyl) methacrylamide) as a doxorubicin-delivery platform and for combination chemotherapy in breast cancer:
Yamini Bobde, Milan Paul, Tarun Patel, Swati Biswas, Balaram Ghosh* (Accepted in International Journal of
Pharmaceutics). [IF: 5.875]
100. Dissecting Histone Deacetylase 3 in Multiple Disease Conditions: Selective Inhibition as a Promising Therapeutic
Strategy: Nilanjan Adhikari, Tarun Jha, Balaram Ghosh*. JMC (Journal of Medicinal Chemistry, ACS):
doi.org/10.1021/acs.jmedchem.0c1676 [IF: 7.446] 
99. Synthesis, Biological Evaluation, and Molecular Docking Analysis of Novel Linker-less Benzamide Based Potent and
Selective HDAC3 Inhibitors: Ganesh Routholla, Sravani Pulya, Tarun Kumar Patel, Sk. Abdul Amin, Nilanjan Adhikari,
Swati Biswas, Tarun Jha, Balaram Ghosh*. Bioorganic Chemistry 114, June 4 (2021), 105050, doi:
10.1016/j.bioorg2021105050. [IF: 5.725]
98. PEGylated N-(2 hydroxypropyl) methacrylamide based polymeric micelles for the delivery of Doxorubicin in breast
cancer: Yamini Bobde, Tarun Patel, Milan Paul, Swati Biswas, Balaram Ghosh*: May 2021; Colloids and Surfaces B:
Biointerface: 204 (2021) 111833 doi.org/10.1016/j.colsurfb.2021.111833. [IF:5.268]
97. Robust classification-based molecular modeling of diverse chemical entities as potential SARS-CoV-2 3CLpro
inhibitors: Theoretical justification in light of experimental evidences: Nilanjan Adhikari, Suvankar Banerjee, Sandip Kumar
Baidya, Balaram Ghosh*, Tarun Jha. SAR and QSAR in Environ Res (Taylor and Francis)
doi:  org/10.1080/1062936X.2021.1914721 [IF: 3.000]
96. Design, synthesis and biological evaluation of 7–(5–((amino)methyl) thiophen–2–yl) spiro[chroman–2,4'–piperidin]–4–
one hydrochloride analogues as anti-tumor agents: Surendar Chitti#, Sravani Pulya#, Adinarayana Nandikolla, Tarun
Kumar Patel, Banoth Karan Kumar, Murugesan Sankaranarayanan, Balaram Ghosh*, KVG Chandra Sekhar. Bioorganic
Chemistry, March 26, 112 (2021) 104865.  doi.org/10.1016/j.bioorg.2021.104865. [IF: 5.725]
95. Distinct rhodamine B derivatives exhibiting dual effect of anticancer activity and fluorescence property : Himabindu
Battula, Sivaganesh Bommi, Yamini Bobde, Tarun Patel, Balaram Ghosh*, Subbalakshmi Jayanty: Journal of
Photochemistry and Photobiology, 6 (2021) 100026, 10 March 2021, doi.org/10.1016/j.jpap.2021.100026 
94.Targeted Bioimaging of Cancer Cells Using Free Folic Acid-Sensitive Molybdenum Disulfide Quantum Dots through
Fluorescence “Turn-off”: Susmita Roy, Yamini Bobde, Balaram Ghosh* and Chanchal Chakraborty. ACS Appl. Bio
Mater. March 3, 2021, 4, 3, 2839-2849. doi.org/10.1021/acsabm.1c00090
93. Polymeric Micelles in Cancer Therapy: State of the Art; Balaram Ghosh and Swati Biswas. Journal of Controlled
Release 332 (2021) 127–147 [IF: 9.776]
92. Small Molecule Drug Conjugate (SMSC): Am Emerging Target for Anticancer Drug Design and Discovery: Tarun
Kumar Patel, Nilanjan Adhikari, Sk. Abdul Amin, Swati Biswas, Tarun Jha, Balaram Ghosh*. Feb 12 2021 New Journal of
Chemistry.  DOI: 10.1039/d0nj04134c [IF: 3.591]
91. PT3: A novel benzamide class histone deacetylase 3 inhibitor Improves Learning and Memory in Novel Object
Recognition Mouse Model: Pulya, Sravani; Mahale, Ashutosh; Bobde, Yamini; Routholla, Ganesh; Patel, Tarun kumar;
Singh, Swati; Biswas, Swati; Sharma, Vivek; Kulkarni, Onkar; Ghosh, Balaram*: ACS Chemical Neuroscience. 2021, 12,
5, 883–892. [IF: 4.418]
 Curriculum Vitae Balaram Ghosh, PhD
90. HDAC6 as privileged target in drug discovery: A perspective; Sravani Pulya, Sk. Abdul Amin, Nilanjan Adhikari, Swati
Biswas, Tarun Jha, Balaram Ghosh*: Pharmacological Research 163 (2021) 105274, doi:
org/10.1016/j.phrs.2020.105274 [IF: 7.658]

2020
89. Lipid-conjugated self-assembled human serum albumin nanoparticles for improved delivery and anticancer activity of
loaded curcumin for targeted cancer treatment: Kumari, Preeti; Paul, Milan; Bobde, Yamini ; Kumbham , Soniya;
Rompicharla, Sri Vishnu Kiran ; Ghosh, Balaram; Biswas, Swati; Nanomedicine-London, 2020 15(29), 2851-2869;
doi: 10.2217/nnm-2020-0232.  [IF: 5.307]
88. Oleanolic acid-conjugated poly (D, L-lactide)-based micelles for effective delivery of doxorubicin and combination
chemotherapy in oral cancer: Soniya Kumbham; Milan Paul; Himanshu Bhatt; Balaram Ghosh, Swati Biswas. Journal of
Molecular Liquids 320 (2020) 114389, 20 Sept. 2020, doi.org/10.1016/j.molliq.2020.114389. [IF: 6.165]
87. Current trends in the development of HPMA-based block co-polymeric nanoparticles for their application in drug
delivery: Yamini Bobde, Swati Biswas, Balaram Ghosh*. European Polymer Journal 139 (2020) 110018 doi:
org/10.1016/j.eurpolymj.2020.[IF: 4.598]
86. Enhanced intestinal stability and pH sensitive release of quercetin in GIT through gellan gum hydrogels: Madhumita
Dey, Balaram Ghosh, Tapan Giri:Colloids Surf B Biointerfaces. 2020 Aug
28;196:111341. doi.org/10.1016/j.colsurfb.2020.111341 [IF: 5.268]
85. Pharmacological blockade of HDAC6 accelerates wound healing in diabetes by regulating IL-1beta and IL-10
expression: Kalyani Chowdary Karnam, Kavitha Sedmaki, Pravesh Sharma, Ganesh Routholla, Sriharshini Goli, Balaram
Ghosh, Venkata Vamsi Krishna Venuganti, Onkar Prakash Kulkarni: Biochimica et Biophysica Acta (BBA) - Molecular
Basis of Disease 1866, 11, (2020)165903: doi.org/10.1016/j.bbadis.2020.165903 [IF: 4.352]
84. Design, Synthesis, and Biological Evaluation of Novel Nicotinamide Derivatives as Potential Selective Histone
Deacetylase-3 Inhibitors. Mohamed M.S. Hamoud #, Sravani Pulya#, Nermine A. Osman, Yamini Bobde, Abdalla E. A.
Hassan, Hanan A. Abdel-Fattah, Balaram Ghosh* Amany M. Ghanim: New Journal of Chemistry  2020, 44 (23), 9671.
DOI: 10.1039/d0nj01274b [#joint first author] [IF: 3.591]
83. Cell penetrating peptide anchored α-tocopherol conjugated Poly (amidoamine) Dendrimers for enhanced tumor
targeting: Himanshu Bhatt, Balaram Ghosh and Swati Biswas. ACS Appl. Bio Mater. 2020, 3, 5, 3157–
3169; doi.org/10.1021/acsabm.0c00179.
82. 6-chloro, 6,7-dichloro and 2-methyl-3-(((1-(substituted-phenyl)-1H-1,2,3-triazol-4-yl)methoxy)carbonyl)quinoxaline-1,4-
dioxide derivatives as anti-tubercular agents: Singireddi Srinivasarao, Adinarayana Nandikolla, Amaroju
Suresh, Napiórkowska Agnieszka, Augustynowicz-Kopec Ewa, Balaram Ghosh, Sankaranarayanan Murugesan, Sravani
Pulya, Himanshu Aggarwa and Kondapalli Venkata Gowri Chandra Sekhar: Bioorganic Chemistry 100 (2020)
103955; doi.org/10.1016/j.bioorg.2020.103955) [IF: 5.725]
81. Seeking potent anti-tubercular agents: Design and synthesis of
subsituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperzine-1-yl)pyridin-3-yl)benzamide derivatives as anti-
tubercular agents: Srinivasarao, Singireddi; Nandikolla, Adinarayana; Amaroju, Suresh; Calster, Kevin Van ; Voogt, Linda
De ; Kappoen, Davie; Ghosh, Balaram;  Aggarwal, Himanshu; Sankaranarayanan, Murugesan; Chandrasekhar, K.: RSC
Advances 2020, 10, 12272 - 12288 doi: 10.1039/d0ra01348j [IF: 3.361]
80. PEGylated  N-(2 hydroxypropyl) methacrylate-Doxorubicin conjugate as pH-responsive polymeric nano-assembly for
cancer treatment: Yamini Bobde, Swati Biswas, Balaram Ghosh*. Reactive and Functional Polymers 151 (2020) 104561.
doi.org/10.1016/j.reactfunctpolym.2020.104561 [IF: 3.975]
79. Chlorin e6 conjugated methoxy-poly(ethylene glycol)-poly(D,L-lactide) glutathione sensitive micelles for photodynamic
therapy: Preeti Kumari, Milan Paul, Himanshu Bhatt, Sri Vishnu Kiran Rompicharla, Debolina Sarkar, Balaram Ghosh,
Swati Biswas: Pharm Research  2020 Jan 2;37(2):18. doi: 10.1007/s11095-019-2750-0. [IF: 4.200]
78. Structure activity relationship of Human Carbonic Anhydrase II inhibitors: Detailed Insight for future development as
anti-glaucoma agents: Soumajit Ghorai, Partha sarathi Panda, Sravani Pulya, Balaram Ghosh* and Shovanlal
Gayen: Bioorganic Chemistry Volume 95, January 2020,  p 10355795 (2020); doi.org/10.1016/j.bioorg.2019.103557 [IF:
5.725]
77. Development and characterization of solid dispersion system for enhancing the solubility and cytotoxicity of dietary
capsaicin: Samit Bera; Subhasis Maity, Balaram Ghosh, Animesh Ghosh, Tapan Kumar Giri:  Current Drug Therapy
(2020) 15 (2), 143-151
 
 Curriculum Vitae Balaram Ghosh, PhD
2019
76. Lipid and poly (ethylene glycol)-conjugated Bi-functionalized Chlorine e6 micelles for NIR-Light Induced Photodynamic
Therapy: Omkara Swami Muddineti, Sri Vishnu Kiran Rompicharla, Preeti Kumari,  Himanshu Bhatt, Balaram Ghosh,
Swati Biswas: Photodiagnosis and Photodynamic Therapy  2019 Dec 20:101633. doi: 10.1016/j.pdpdt.2019.101633  [IF:
3.631].
75. Quinoline Consist of 1H-1,2,3-Triazole Hybrids: Design, Synthesis and Anticancer Evaluation: Sivarami Reddy
Gangireddy Venkata, Umesh. C. Narkhede, Vinod. D Jadhav, Naidu Gangu, Ramakrishnam Raju Addada, Sravani
Pulya, Balaram Ghosh. ChemistrySelect 2019, 4, 14184–14190 doi.org/10.1002/slct.201903938. [IF: 2.109]
74. Development and characterization of phospholipid complex for effective delivery of capsaicin: Ranadip Mondal,
Yamini Bobde, Balaram Ghosh, Tapan Kumar Giri: Indian Journal of Pharmaceutical Sciences (IJPS) 81(6); 2019:
doi: 10.36468/pharmaceutical-sciences.598. [IF: 0.975]
73. Transferrin/α-tocopherol modified PAMAM Dendrimers for improved tumor targeting and anticancer activity of
Paclitaxel; Himanshu Bhatt, Sri Vishnu Kiran Rompicharla, Balaram Ghosh, Vladimir Torchilin, and Swati
Biswas. Nanomedicine (Lond). 2019 Dec;14(24):3159-3176. doi: 10.2217/nnm-2019-0128. [IF: 5.307]
72. Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimiazoles as novel inhibitors of LasR
dependent Quorum Sensing in Pseudomonas aeruginosa: Srinivasarao, Singireddi; Nandikolla, Adinarayana; Nizlapur,
Shashidhar; Yu, Tsz Tin; Pulya, Sravani; Ghosh, Balaram; Sankaranarayanan, Murugesan; Kumar, Naresh;
Chandrasekhar, K. RSC Advances,  2019, 9, 29273-29292. [IF: 3.361]
71. Fused chromeno-thieno/furo-pyridines as potential analogs of lamellarin D and their anticancer activity evaluation: T.
Uday Kumar, Yamini Bobde, Sravani Pulya, Krishnan Rangan, Balaram Ghosh, Anupam
Bhattacharya: ChemistrySelect; 24 September 2019: doi: https://doi.org/10.1002/slct.201902946. [IF: 2.109]
70. Design, synthesis, biological evaluation and molecular docking study of arylcarboxamido piperidine and piperazine-
based hydroxamates as potential HDAC8 inhibitors with promising anticancer activity: Prakruti Trivedi, Nilanjan Adhikari,
Sk. Abdul Amin, Yamini Bobde, Routholla Ganesh, Tarun Jha, Balaram Ghosh*: European Journal of Pharmaceutical
Sciences 138 (2019) 105046:  doi.org/10.1016/j.ejps.2019.105046. [IF: 4.384]
69. Design, synthesis and biological evaluation of 2-(3, 4-dimethoxyphenyl)-6 (1,2,3,6-tetrahydropyridin-4-yl) imidazo [1,2-
a]pyridine analogues as antiproliferative agents: Surendar Chitti; Srinivasarao Singireddi; Santosh Kumar Reddy
Pochana; Prakruti Trivedi; Yamini Bobde; Chandan Kumar; Krishnan Rangan; Balaram Ghosh*;  KVG Chandra Sekhar*:
August 2019: Bioorganic & Medicinal Chemistry Letters: doi: 10.1016/j.bmcl.2019.08.013. [IF:2.823]
68. FP253 HDAC6 regulates secretion of IL-1β in calcium oxalte crystal stimulated macrophages and its implications in
crystal nephopathy: Kavitha Sedmaki, Kalyani Karnam, Pravesh Sharma, Balaram Ghosh, Onkar Kulkarni: Nephrology
Dialysis Transplantation, Volume 34, Issue Supplement_1, June 2019, gfz106.FP253, 13 June
2019: doi.org/10.1093/ndt/gfz106.FP253 [IF 5.992]
67. 2-phenylindole derivatives as anticancer agents: synthesis and screening against murine melanoma, human lung and
breast cancer cell lines: Ruchi Gaikwad, Yamini Bobde, Routholla Ganesh, Tarun Patel, Balaram Ghosh, Kalpataru Das,
Shovanlal Gayen. (2019) Synthetic Communications: doi.org/10.1080/00397911.2019.1620282]  [IF: 2.007]
66. Design, Synthesis and Anti-tumor Activity Evaluation of Novel Hybrid Molecules of Pyrimidine-Pyrole Appended
Triazoles: Arunkumar Thiriveedhi, Ratnakaram Venkata Nadh, Yamini Bobde Navuluri Srinivasu, Balaram Ghosh,
KVG Chandra Sekhar: Toxicology in Vitro  60 (2019) 87–96: doi.org/10.1016/j.tiv.2019.05.009 [IF: 3.500]
65. A folic acid-sensitive polyfluorene based “turn-off” fluorescence nanoprobe for folate receptor overexpressed cancer
cell imaging: Susmita Roy; Anusha Gunukula; Balaram Ghosh; Chanchal Chakraborty: Sensors & Actuators:
B. Chemical. Volume 291, 337-344 (2019); doi: org/10.1016/j.snb.2019.04.029 [IF: 7.460]
64. First report on 3-(3-oxoaryl) indole derivatives as anticancer agents: Microwave assisted synthesis, in vitro screening
and molecular docking studies Tarun patel; Ruchi Gaikwad; Kavita Jain; Routholla Ganesh; Yamini Bobde; Balaram
Ghosh; Kalpataru Das; Shovanlal Gayen: ChemistrySelect  2019, 4, 4478–4482 doi: 10.1002/slct.201900088. [IF; 2.109]
63. Photo and Electrocatalytic degradation of dye using ZIF derived ZnO: Payra, Soumitra; Challagulla, Swapna; Bobde,
Yamini; Chakraborty, Chanchal; Ghosh, Balaram; Roy, Sounak. Journal of Hazardous Materials 373 (2019) 377–
388: DOI: 10.1016/j.jhazmat.2019.03.053. [IF: 10.588]]
62. α-tocopherol succinate anchored PEGylated Poly(Amidoamine) Dendrimer for the Delivery of Paclitaxel: in vitro and
in-vivo therapeutic efficacy: Himanshu Bhatt, Sri Vishnu Kiran Rompicharla, Balaram Ghosh, Swati Biswas: ACS
Molecular Pharmaceutics 2019 Feb 28. doi: 10.1021/acs.molpharmaceut.8b01232. [IF: 4.939]
61. Histone deacetylase 3 inhibitors in learning and memory processes with special emphasis on benzamides:  Amin
SA, Adhikari N, Kotagiri S, Jha T, Ghosh B*: European Journal of Medicinal Chemistry 166 (2019):369-380. [IF: 6.514]
 Curriculum Vitae Balaram Ghosh, PhD
60. Biotin Functionalized Poly(Amidoamine) PEGylated Dendrimer conjugate for Active Targeting of Paclitaxel in cancer:
Sri Vishnu Kiran Rompicharla, Preeti Kumari, Himanshu Bhatt, Balaram Ghosh, Swati Biswas. International Journal of
Pharmaceutics: 2019 Feb 25;557: 329-341. doi: 10.1016/j.ijpharm.2018.12.069 [IF: 5.875]
59. Tandem Schiff Base Formation/Heterocyclization Reaction: A Facile Entry to the Synthesis of Fused Pyrazolo-
Pyrimidine/Isoxazolo-Pyrimidine Hybrids: M. Sambaiah, Poosa Mallesham, K. Shiva Kumar, Yamini Bobde, Prasanta
Kumar Hota, Satyanarayana Yennam, Balaram Ghosh, Manoranjan Behera.  2019 Synlett 30 (05), 586-592, DOI:
10.1055/s-0037-1612081. [IF:2.454]
58. Development of chlorin e6-conjugated poly(ethylene glycol)-poly(d,l-lactide) nanoparticles for photodynamic therapy:
Kumari P, Kiran Rompicharla SV, Bhatt H, Ghosh B, Biswas S.: Nanomedicine (Lond). 2019 Mar 15. doi: 10.2217/nnm-
2018-0255. [IF: 5.307]
57. Vitamin-E/Lipid Based PEGylated Polymeric Micellar Doxorubicin to sensitize Doxorubicin-resistant cells towards
treatment: Omkara Swami Muddineti, Sri Vishnu Kiran Rompicharla, Preeti Kumari, Himanshu Bhatt, Balaram Ghosh,
Swati Biswas. Reactive and Functional Polymers;Vol 134 (49-57), Jan 2019;
doi.org/10.1016/j.reactfunctpolym.2018.10.012 [IF: 3.975].
56. Designing potential HDAC3 inhibitors to improve memory and learning: Sk. Abdul Amin, Nilanjan Adhikari, Tarun
Jha, Balaram Ghosh*. Journal of Biomolecular Structure and Dynamics. 2019, 37(8), 2133-2142, doi:
10.1080/07391102.2018.1477625; [IF: 3.12]
 
2018
55. Design, Synthesis and anti-cancer evaluation of Novel Spiro[cyclohexane-1,1'-indene]-2,5-diene analogues: Sivarami
Reddy, Gangireddy Venkata; Umesh C Narkhede; Vinod D Jadav; Gangu Naidu; Yamini Bobde; Balaram
Ghosh; ChemistrySelect; (7 Nov. 2018); DOI: 10.1002/slct.201802675. [IF; 2.109]
54. The Structural and Surface Modification of Zeolitic Imidazolate Framework Material Towards CO2 Storage and
Reduction: Payra, Soumitra; Challagulla, Swapna; Chakraborty, Chanchal; Kartick Tarafder; Ghosh, Balaram;
Roy, Sounak: (New Journal of Chemistry) (2018) DOI: 10.1039/C8NJ04247K [IF: 3.591]
53. HDAC3 is a potential validated target for cancer: An overview on the benzamide-based selective HDAC3 inhibitors
through comparative SAR/QSAR/QAAR approaches: Nilanjan Adhikari, Sk. Abdul Amin, Prakruti Trivedi, Tarun
Jha; Balaram Ghosh*: European  Journal of Medicinal Chemistry:  157 (2018) 1127-1142:
doi.org/10.1016/j.ejmech.2018.08.081 [IF: 6.514]
52. Design, Synthesis and Biological Evaluation Histone deacetylase 3 inhibitors as Promising Treatment Strategy for
Cancer: Prakruti Trivedi Nilanjan Adhikari, Sk. Abdul Amin, Tarun Jha, Balaram Ghosh*:  European Journal of
Pharmaceutical Sciences: 124 (2018) 165–181: doi.org/10.1016/j.ejps.2018.08.030. [IF: 4.384]
51. Design, Synthesis and Biological Evaluation of Triazole-containing 2-Phenylindole and Salicylic Acid as Quorum
Sensing Inhibitors against Pseudomonas aeruginosa:  Singireddi Srinivasarao, Shashidhar Nizalapur, Tsz Tin Yu, Daniel
Stanley Wenholz, Prakruti Trivedi,  Balaram Ghosh, Krishnan Rangan, Naresh Kumar, KVG Chandra
Sekhar: ChemistrySelect 2018, 3, 9170–9180. [IF: 2.109]
50. Evaluation of Anti-tumor Efficacy of Vorinostat Encapsulated Self Assembled Polymeric Micelles in solid tumors: Sri
Vishnu Kiran Rompicharla, Prakruti Trivedi, Preeti Kumari, Omkara Swami Muddineti, Sowmya Theegalapalli, Balaram
Ghosh, Swati Biswas: AAPS PharmSciTech. 2018 Aug 21. doi: 10.1208/s12249-018-1149-2. [IF: 3.246]
49. Cholesterol-grafted chitosan micelles as a nanocarrier system for drug-siRNA co-delivery in cancer cells" by Omkara
Swami Muddineti, Aashma Shah, Sri Vishnu Kiran Rompicharla, Balaram Ghosh, Swati Biswas. International Journal of
Biological Macromolecules  2018 Jun 25;118(Pt A):857-863. doi: 10.1016/j.ijbiomac.2018.06.114. [IF: 6.953]
48. Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory: Wen-Ning
Zhao, Balaram Ghosh, Marshall Tyler, Jasmin Lalonde, Nadine F. Joseph, Nina Kosaric, Daniel M. Fass, Li-Huei Tsai,
Ralph Mazitschek, Stephen J. Haggarty: ACS chemical neuroscience 9 (9), 2262-2273, 2018, doi:
10.1021/acschemneuro.8b00116. [IF: 4.418]
47. Transferrin-anchored poly(lactide) micelles to improve anticancer activity of curcumin in hepatic and cervical cancer
cell monolayers and 3D spheroids: Kumari Preeti; Rompicharla, Sri Vishnu Kiran; Muddineti, Omkara Swami; Ghosh,
Balaram; Biswas Swati:  International Journal of Biological Macromolecule. 2018 May 9. doi:
10.1016/j.ijbiomac.2018.05.040. [IF: 6.953]
46. Intracellularly Targeted Multifunctional Poly(Amidoamine) Dendrimer for Improve Delivery and cytotoxic effect of
Paclitaxel in cancer: Sri Vishnu Kiran Rompicharla, Preeti Kumari, Balaram Ghosh, Swati Biswas. Artif Cells Nanomed
Biotechnol. 2018 May 23:1-13. doi: 10.1080/21691401.2018.1470527. [IF: 5.678].
 Curriculum Vitae Balaram Ghosh, PhD
45. Transferrin-modified Vitamine-E/lipid based polymeric micelles for improved tumor targeting and anticancer effect of
curcumin: Omkara Swami Muddineti, Preeti Kumari, Balaram Ghosh, Swati Biswas. Pharm Res.( Pharmaceutical
Research.) 2018 Mar 14;35(5):97. doi: 10.1007/s11095-018-2382-9.  [IF: 4.200]
44. Development of curcumin-loaded solid lipid nanoparticles utilizing glyceryl monosterate as lipid using QbD approach:
Characterization and Evaluation of anticancer activity against human breast cancer cell line: Himanshu Bhatt, Sri Vishnu
Kiran Rompicharla, Neeraja Komanduri, Shah Aashma, Sateja Paradkar, Balaram Ghosh, Swati Biswas. Current Drug
Delivery. Curr Drug Deliv. 2018 May 3. doi: 10.2174/1567201815666180503120113  [IF: 2.562]
43. Design, Synthesis and Anticancer Activity of Novel Quinone Bearing Carbamyl β-Lactam Hybrids: Nagaraju
Payili, Satyanarayana Yennam, Santhosh Reddy Rekula, Challa Gangu Naidu, Yamini Bobde, Balaram Ghosh: Journal
of Heterocyclic Chemistry: 17 April 2018, https://doi.org/10.1002/jhet.3169 (Wiley). [IF: 2.193]
42. Cholesterol and Vitamin E-conjugated PEGylated Polymeric micelles for efficient delivery and enhanced anticancer
activity of curcumin: Evaluation in 2D monolayers and 3D spheroids: Muddineti, Omkara Swami; Vanaparthi, Asmitha;
Rompicherla, Sri Vishnu Kiran; Kumari, Preeti; Ghosh, Balaram; Biswas, Swati: Artificial Cells, Nanomedicine and
Biotechnology. 2018 Feb 9:1-14. doi: 10.1080/21691401.2018.1435551 [IF: 5.678].
 
2017
41. Shedding light on designing potential meprin β inhibitors through ligand-based robust validated computational
approaches: A proposal to chemists! Nilanjan Adhikari,a, Sk. Abdul Amin, Balaram Ghosh*, Tarun Jha. Journal of
Biomolecular Structure and Dynamics. 2017 Sep 20:1-20. doi: 10.1080/07391102.2017.1374210. [IF: 3.12]
40. FRET Mediated Zn2+ Sensing in Aqueous Micellar Solution and its Application in Cellular Imaging: Shweta Pawar, T.
Uday Kumar, Prakruti Trivedi, Balaram Ghosh, Anupam Bhattacharya, Amit Nag. ChemistrySelect 2017, 2, 8731– 8737.
[IF: 2.109]
39. Formulation optimization, characterization, and evaluation of in vitro cytotoxic potential of Curcumin loaded solid lipid
nanoparticles for improved anticancer activity: Sri Vishnu Kiran Rompicharla, Bhatt Himanshu, Aashma Shah, Neeraja
Komanduri, Dhanya Vijayasarathy, Balaram Ghosh, Swati Biswas. Chem Phys Lipids. 2017 Aug 23; 208:10-18. doi:
10.1016/j. Chemistry and Physics of Lipids.2017.08.009. [IF: 3.329]
38. Polylactide-based block co-polymeric micelles loaded with Chlorin e6 for Photodynamic Therapy: In vitro evaluation in
Monolayer and 3D spheroid models: Preeti Kumari, Shreya Jain, Balaram Ghosh, Vladimir Zorin, Swati
Biswas. Molecular Pharmaceutics (ACS) 2017 Oct 9. doi: 10.1021/acs.molpharmaceut.7b00548 [IF: 4.939]
37. p-TSA promoted syntheses of 5H-benzo[h]thiazolo[2,3-b]quinazoline and  indeno[1,2-d]thiazolo[3,2-a]pyrimidine
analogues: Molecular modeling, in-vitro antitumor activity against hepatocellular carcinoma: Amit K Keshari, Ashok K
Singh, Vinit Raj, Amit Rai, Prakruti Trivedi, Balaram Ghosh, Umesh Kumar, Atul Rawat, Dinesh Kumar, Sudipta
Saha: Drug Des Devel Ther. 2017 May 29; 11:1623-1642. doi: 10.2147/DDDT.S136692. [IF: 4.162]
36. Curcumin loaded chitosan cholesterol micelles: Evaluation in monolayers and 3-D cancer spheroid model: Omkara
Swami Muddineti, Preeti Kumari, Eupa Ray, Balaram Ghosh, Swati Biswas: Nanomedicine (Lond). 2017 Jun 2. doi:
10.2217/nnm-2017-0036. [IF: 5.307]
35. Discovery of Novel 2-Amino-5-(Substituted)-1,3,4-Thiadiazole Derivatives: New Utilities for Colon Cancer Treatment:
Raj V, Rai A, Singh AK, Keshari AK, Trivedi P, Ghosh B, Kumar U, Kumar D, Saha S. Anticancer Agents Med
Chem. 2017 Apr 19. doi: 10.2174/ 1871520617666170419122916. [Epub ahead of print] [IF: 2.505]
34. D-α-Tocopheryl succinate/phosphatidyl ethanolamine conjugated amphiphilic polymer based nano-micellar system for
the efficient delivery of curcumin and to overcome multiple drug resistance in cancer: Muddineti, Omkara Swami; Kumari,
Preeti; Ghosh, Balaram; Torchilin, Vladimir; Biswas, Swati. ACS Appl Mater Interfaces. 2017 May 24; 9(20):16778-
16792. doi: 10.1021/acsami.7b01087. [IF: 9.229]
33. One-Step Synthesis of Fused Chromeno[4,3-b]pyrrolo [3,2-h]quinolin-7(1H)-One Compounds and their Anticancer
Activity Evaluation: Yadagiri Thigulla, T. Uday Kumar, Prakruti Trivedi, Balaram Ghosh, Anupam
Bhattacharya: ChemistrySelect 2017, 2, 2721 – 2724. [IF: 2.109]
 
2016
32. Polymeric micelles of suberoylanilide hydroxamic acid to enhance the anticancer potential in vitro and in vivo: Sri
Vishnu Kiran Rompicharla#, Prakruti Trivedi#, Preeti Kumari, Prathyusha Ghanta, Balaram Ghosh, and Swati
Biswas. Nanomedicine, November 23, 2016. (doi:10.2217/nnm-2016-0321) [IF: 5.307]
 Curriculum Vitae Balaram Ghosh, PhD
31. Cholesterol-conjugated poly(D, L-Lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in
cancer therapy: Kumari, Preeti; Muddineti, Omkara; Rompicharla, Sri Vishnu Kiran; Ghanta, Pratyusha; B B N, Adithya
Karthik; Ghosh, Balaram; Biswas, Swati: Drug Delivery (Taylor & Francis). Aug 2016 [IF: 6.419]
30. Current trends in the use of vitamin E-based micellar nanocarriers for anticancer drug delivery. Omkara S
Muddineti, Balaram Ghosh, Swati Biswas: Expert Opin Drug Deliv. 2016 Sep 6:1-12. DOI:
10.1080/17425247.2016.1229300 [IF: 6.648]
29. Metal-free arylation to access distinct anthracenylphosphonates and anticancer activities for these and allied
phosphonates: M. Zubair K. Baig, Gangaram Pallikonda, Prakruti Trivedi, R.N. Prasad, Balaram Ghosh, Manab
Chakravarty; ChemistrySelect 2016, 1, 4332 – 4339 (DOI: 10.1002/slct.201600978). [IF: 2.109]
28. Xanthan gum stabilized PEGylated Gold nanoparticles for improved delivery of curcumin in cancer: Omkara S
Muddineti, Preeti Kumari, Srinivas Ajjarapu, Prit M Lakhani, Balaram Ghosh, Swati Biswas: Nanotechnology 2016
Jun  27;27(32):325101. [IF: 3.874].
27. Light Controlled Modulation of Gene Expression by Chemical Optoepigenetic Probe: Surya A. Reis#, Balaram
Ghosh#, J. Adam Hendricks, D. Miklos Szantai-Kis, Kenneth N. Ross, Justin Lamb, Willis Read-Button, Baixue Zheng,
Hongtao Wang, Christopher Salthouse, Stephen J. Haggarty, Ralph Mazitschek: Nat Chem Biol. (Nature Chemical
Biology) 2016 Mar 14. doi: 10.1038/nchembio.2042. [Epub ahead of print] [IF: 15.04] [#Joint first author]
26. Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic
regulation: Balaram Ghosh, Wen-Ning Zhao, Surya A Reis; Debasis Patnaik; Daniel M Fass; Li-Huei Tsai; Ralph
Mazitschek, Stephen J. Haggarty. Bioorganic Medicinal Chemistry Letters, 2016 Feb 15;26(4):1265-71. doi:
10.1016/j.bmcl.2016.01.022. Epub 2016 Jan 11. [IF: 2.823].
25. Recent advances in polymeric micelles for anti-cancer drug delivery: Swati Biswas, Preeti Kumari, Prit M
Lakhani, Balaram Ghosh*; European Journal of Pharmaceutical Sciences; 2016 Feb. doi: 10.1016/j.ejps.2015.12.031 [IF:
4.384].
24. Isolated flavonoids from Ficus racemosa stem bark possess antidiabetic, hypolipidemic and protective effects in albino
Wistar rats: Amit K Keshari, Ghanendra Kumar, Priya   S Kushwaha, Monika Bhardwaj, Pranesh Kumar, Atul Rawat,
Anand Prakash, Balaram Ghosh, Sudipta Saha; Journal of Ethnopharmacology 2016 Apr 2;181:252-62. doi:
10.1016/j.jep.2016.02.004. [IF: 4.360]
 
2015
23. Curcumin Delivery by Poly(Lactide)-Based Co-Polymeric Micelles: An In Vitro Anticancer Study; Kumari P, Swami
MO, Nadipalli SK, Myneni S, Ghosh B, Biswas S. Pharm Res. 2015 Nov 23. DOI: 10.1007/s11095-015-1830-z [Epub
ahead of print] [IF: 4.200]
22. Synthesis and anti-cancer activity of 1, 4-disubstituted imidazo[4,5-c]quinolines; Yadagiri Thigulla, Mahesh
Akula, Prakruti Trivedi, Balaram Ghosh, Mukund Jha, Anupam Bhattacharya; Organic & Biomolecular
Chemistry · November 2015; DOI: 10.1039/C5OB01650A [IF: 3.876]
21. An overview of synthetic strategies and current applications of gold nanorods in cancer treatment: Lakhani, Prit;
Rompicharla, Sri Vishnu Kiran; Ghosh, Balaram; Biswas Swati; Nanotechnology 2015 Oct 30;26(43):432001. doi:
10.1088/0957-4484/26/43/432001. Epub 2015 Oct 8 [IF: 3.874]
20. Nanocarriers for cancer-targeted drug delivery: Kumari P, Ghosh B, Biswas S: Journal of Drug Targeting. 2015 Jun
10:1-13. [IF: 5.121].
19. Current trends in using polymer coated gold nanoparticles for cancer therapy: Muddineti O S, Ghosh B, Biswas
S; International Journal of Pharmaceutics 2015 Apr 30;484(1-2):252-67. doi: 10.1016/j.ijpharm.2015.02.038. [IF: 5.875]

2014
18. Monoalkoxy BODIPYs - A Fluorophore Class Optimized for Bioimaging: Courtis, Alexandra; Hendricks,
James; Ghosh, Balaram; Szantai-Kis, Daniel; Reis, Surya; Santos, Sofia; Guan, Yinghua; Shah, Jagesh; Mazitschek,
Ralph; Bioconjugate Chemistry, 2014 Jun 18; 25(6):1043-51. doi: 10.1021/bc400575w. [IF: 4.774]
17. Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma: Minami J, Suzuki R, Mazitschek R,
Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ,
Richardson PG, Hideshima T, Anderson KC. Leukemia-nature (2014) 28, 680–689 DOI: 10.1038/leu.2013.231 [IF:
11.528]
 Curriculum Vitae Balaram Ghosh, PhD
 
Before joining at BITS-Pilani, Hyderabad Campus (September 2013…………….
 16. Crebinostat: A Novel Cognitive Enhancer that Inhibits Histone Deacetylase Activity and Modulates Chromatin-
Mediated Neuroplasticity: Daniel M. Fass, Surya A. Reis, Balaram Ghosh, Krista M. Hennig, Nadine F. Joseph, Wen-
Ning Zhao, Thomas J.F. Nieland, Ji-Song Guan, Chelsea E. Groves Kuhnle, Weiping Tang, Douglas D. Barker, Ralph
Mazitschek, Stuart L. Schreiber, Li-Huei Tsai, Stephen J. Haggarty. Neuropharmacology. 2013 Jan; 64:81-96. doi:
10.1016/j.neuropharm.2012.06.043. Epub 2012 Jul 4. [IF: 5.250]
15. Synapse microarray identification of small molecules that enhance synaptogenesis: Peng Shi, Mark A Scott, Balaram
Ghosh, Dongpeng Wan, Zachary Wissner-Gross, Ralph Mazitschek, Stephen J. Haggarty & Mehmet F Yanik. Nat
Commun. (Nature Communication) 2011 Oct 25; 2:510. doi: 10.1038/ncomms1518 [IF: 14.919].
14. Targeting chromatin-mediated neuroplasticity by inhibition of histone deacetylase (HDAC) with short-chain carboxylic
acids and their hydroxamic acid analogs: Daniel M. Fass, Rishita Shah, Balaram Ghosh, Krista Hennig, Stephanie
Norton, Wen-Ning Zhao, Surya A. Reis, Peter S. Klein, Ralph Mazitschek, Rebecca L. Maglathlin, Timothy A. Lewis, and
Stephen J. Haggarty: ACS Med. Chem. Lett. 2010 Oct 8;2(1):39-42 [IF: 4.345].
13. Further delineation of hydrophobic binding sites in dopamine D2/D3 receptors for N-4 substituents on the piperazine
ring of the hybrid template 5/ 7-{[2-(4-Aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: Ghosh,
B., Antonio, T., Gopishetty, B., Reith, M., Dutta, A.; Bioorganic & Medicinal Chemistry 18 (2010) 5661–5674. [IF: 3.641].
12. Discovery of 4-(4-(2-((5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)-ethyl)piperazin-1-yl)quinolin-8-ol
and its analogues with dopamine D2/D3 agonists activity with a capacity to bind to iron: potential application in
neuroprotective therapy for Parkinson’s Disease: Ghosh, Balaram; Antonio, Tamara; Reith, Maarten; Dutta,
Aloke:  Journal of Medicinal Chemistry 2010 Mar 11; 53(5); 2114-25. [IF: 7.446].
11. Development of (S)-N6-Propyl-N6-(2-(4-(quinolin-5-yl)piperazin-1-yl)ethyl)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-
diamine as a D3 receptor preferring agonist with antioxidant activity: Potent in vivo activity in Parkinson’s disease animal
models: Ghosh, Balaram; Antonio, Tamara; Zhen, Juan; Kharkar, Prashant S.; Reith, Maarten E. A.; Dutta, Aloke
K.: Journal of Medicinal Chemistry  2010; 53(3); 1023-37. [IF: 7.446].
10. D-161, a novel pyran-based triple monoamine transporter blocker: Behavioral pharmacological evidence for
antidepressant-like action: Dutta, Aloke K.; Ghosh, Balaram; Biswas, Swati; Reith, Maarten E. A.: European Journal of
Pharmacology (2008), 589(1-3), 73-79. [IF: 4.432].
9. Bioisosteric Heterocyclic Versions of 7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-
ol: Identification of Highly Potent and Selective Agonists for Dopamine D3 Receptor with Potent in Vivo Activity.:      
Biswas, Swati; Hazeldine, Stuart; Ghosh, Balaram; Parrington, Ingrid; Kuzhikandathil, Eldo; Reith, Maarten E. A.; Dutta,
Aloke K.: Journal of Medicinal Chemistry  (2008), 51(10), 3005-3019. [IF: 7.446].
8. Further Structure-Activity Relationships Study of Hybrid 7-{[2-(4-Phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-
tetrahydronaphthalen-2-ol Analogues: Identification of a High-Affinity D3-Preferring Agonist with Potent in Vivo Activity
with Long Duration of Action.: Biswas, Swati; Zhang, Suhong; Fernandez, Fernando; Ghosh, Balaram; Zhen, Juan;
Kuzhikandathil, Eldo; Reith, Maarten E. A.; Dutta, Aloke K.: Journal of Medicinal Chemistry   (2008), 51(1), 101-117. [IF:
7.446].
7. QSAR analysis of some indirubin derivatives as potent and selective inhibitors of cyclin-dependent kinases and
glycogen synthase kinase-3.: Samanta, Soma; Gayen, Shovanlal; Ghosh, Balaram; Panda, Parthasarathi; Srikanth,
Kolluru; Jha, Tarun.: International Journal of Applied Chemistry (2006), 2(2-3), 169-180. [IF: 1.010]
6. QSAR modeling on dopamine D2 receptor binding affinity of 6-methoxy benzamides: Samanta, Soma; Debnath,
Bikash; Gayen, Shovanlal; Ghosh, Balaram; Basu, Anindya; Srikanth, Kolluru; Jha, Tarun.: IL
Farmaco (2005), 60(10), 818-825.
5. 1,5-N,N'-disubstituted-2-(substituted benzenesulphonyl)glutamamide analogues as anticancer agents. Part 3.
Synthesis, biological screening and QSAR study.: Gayen, Shovanlal; Debnath, Bikash; Samanta, Soma; Ghosh,
Balaram; Basu, Anindya; Jha, Tarun.: Internet Electronic Journal of Molecular Design (2005), 4(8), 556-578.
4. QSAR study on 5 N-substituted-2 (substituted benzenesulphonyl) glutamines as antitumor agents through synthesis
and biological evaluation: Part III.: Debnath, Bikash; Samanta, Soma; Gayen, Shovanlal; Basu, Anindya; Ghosh,
Balaram; Jha, Tarun.: Internet Electronic Journal of Molecular Design (2005), 4(6), 393-412.
3. QSAR study on some ethenesulfonamide derivatives as endothelin receptor antagonists: Gayen, Shovanlal; Debnath,
Bikash; Basu, Anindya; Samanta, Soma; Ghosh, Balaram; Naskar, Sudip Kumar; Jha, Tarun.: Internet Electronic Journal
of Molecular Design (2005), 4(3), 210-220.
 Curriculum Vitae Balaram Ghosh, PhD
2. Quantitative structure-activity relationship study using refractotopological state atom index on some neonicotinoid
insecticides.: Debnath, Bikash; Gayen, Shovanlal; Basu, Anindya; Ghosh, Balaram; Srikanth, Kolluru; Jha,
Tarun.: Bioorganic & Medicinal Chemistry (2004), 12(23), 6137-6145. [IF: 3.641].
1. Synthesis, screening and quantitative structure-activity relationship (QSAR) studies of some glutamine analogues for
possible anticancer activity.: Srikanth, K.; Kumar, Ch. Anil; Ghosh, Balaram; Jha, Tarun.: Bioorganic & Medicinal
Chemistry (2002), 10(7), 2119-2131. [IF: 3.641].
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Conference Presentations/Proceedings (Total of 61 till date):

2021………
61. Oleanoic Acid Conjugated Human Serum Albumin- A Nanocarrier for Effective Delivery of Doxorubicin and
Combination Therapeutic Effect in Oral Cancer: Soniya Kumbham, Milan Paul, Balaram Ghosh, Swati Biswas: CRS-IC,
19th International e- symposium On Advances in technology and business potential of new drug delivery systems; Date:
25th-27th February 2021
60. Harnessing Chitasan Vitamin E Succinate Conjugated Supramolecular Micellar Nanoaggregate for Effective Loading
of Oxaliplatin as Breast Cancer Therapy: Asif Mohd itoo, Milan Paul, Balaram Ghosh, Swati Biswas: CRS-IC, 19th
International e- symposium On Advances in technology and business potential of new drug delivery systems; Date: 25th-
27th February 2021
59. Oxaliplatin-Conjugated Stimuli-Sensitive Albumin Nanoparticles for the Treatment of Breast Adeno-Carcinoma: Milan
Paul, Nageswara Rao, Balaram Ghosh, Swati Biswas: CRS-IC, 19th International e- symposium On Advances in
technology and business potential of new drug delivery systems; Date: 25th-27th February 2021

2020
58. Delivery of Doxorubicin Using pH Responsive Polymer: Yamini Bobde, Swati Biswas and Balaram Ghosh; 18th
International Symposium on Advances in Technology and Business Potential of New Drug Delivery Systems, Controlled
Release Society- Indian Chapter; 28-29 February 2020; Vile Parle East, Mumbai - 400 099

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