PATHOPHYSIOLOGY

Predisposing Factors Etiology Precipitating Factors

Prior ischemic attack none diet fatty foods
Age 70y/o socio-economic factors
Gender male stress
Hx of heart disease HPN
Formation of fatty streaks on
arterial wall
Formation of lag!e
"car tiss!e formation
#estriction of exansion and
contraction of arteries
$lood stasis
$lood coag!la%ility
&hrom%osis 'islodging of %lood
clot
(oins general
circ!lation
)m%olism
"tim!lates hyothalam!s
Anterior it!itary gland "ymathoadrenal med!llary resonse
"ymathetic ner*o!s system
Adrenal med!lla
"ecretes einehrine+ noreinehrine
gl!cocorticoids mineralocorticoids
,ortical secretion Aldosterone secretion
Na and H-. retention
olig!ria
$lood *ol!me
,ardiac o!t!t
,H.N
meta%olism
Fat cells Gl!coge-
nesis
gl!cose
Fatty acids
Altered imm!ne system
%ronchodilation
Hyer*entilation - ##
P!il dilation
/ide eyed
0is!al
recetors
&achycardia
,ardiac o!t!t
$lood ress!re
,ontin!o!s eriheral
resistance
"tim!lation of nociceti*e ne!ral
recetors
Nae ain
C
A B
A B C
1in!te *essels dilate
ress!re 2 weakness of *essels
#!t!re of hyertensi*e *essels
3ntracere%ral Hemmorhage
$lood sills on %rain tiss!e
Formation of %lood clot
"ace occ!ying lesion
3nflammatory resonse triggered
0eno!s ret!rn
,ardiac o!t!t
Hyotension
,ere%ral %lood flow
Hyoxia
3schemia "yncoe
3nfarction
Necrosis
,aillary ress!re
,ere%ral )dema
,omression of %rain tiss!e
D
$rain comlies to in ress!re witho!t 3,P
'islacement of ,"F into sinal canal
3,P ,ontin!o!s %rain tiss!e comression
,omensation %y %lood *ol!me in the %rain
F!rther tiss!e hyoxia
Necrosis
,omensation %y dislacement of %rain tiss!e as
manifested %y4 BP, BT+ ##+ P#+ widened
!lse ress!re+ agitation+ na!sea+ *omiting+
sei5!res+ di55iness+ and drowsiness
,ontin!es tiss!e dislacement
6ethargy "t!or
'eath
D
Anterior cere%ral artery
Frontal lo%e
Premotor area
Ahraxia
1otor cortex left
side
Ner*e fi%ers cross
o*er yramidal tract
#ight sided
hemilegia
"trong flexor m!scles /
o*er%alances extensor
"erio!s deformities
1iddle cere%ral artery
Parietal lo%e
/ernicke7s area
#eceti*e Ahasia
Frontal lo%e
$rocha7s area
)xressi*e
Ahasia
Parietal+ occiital+
temoral lo%es
Agnosia
Posterior cere%ral artery Posteroinferior artery
1ed!lla
o%longata
'yshonia
#A"
6.,
$rainstm cere%ell!m 8,N 0+
033+ 39+ 9+ 933:
'ysarthria
'yshagia