PLAN OF WORK 2014

Department of Pharmaceutics, Arya College of Pharmacy, Jaipur (Raj.) Page 1

PLAN OF WORK

Literature Survey

Selection of polymers and its combination with drug

Preformulation studies

Formulation and Development of Pulsatile drug delivery systems.

Evaluation of the formulation Pulsatile Tablets

Stability studies of the formulation.

Analytical Methods

Result and discussion.








PLAN OF WORK 2014

Department of Pharmaceutics, Arya College of Pharmacy, Jaipur (Raj.) Page 2









PLAN OF WORK:
[67, 68, 69, 70]
1. Literature survey: Review of literature related to Drug Profile, excipients profile and
Formulation development.
2. Identification, Selection, and characterization of drug and excipients.
3. Preformulation study.Compatibility Study drug excipient interaction study is necessary
prerequisite to development of dosage form that are stable and good quality.
4. Formulation and Development of Pulsatile drug delivery systems.
A. Development of formulation by using different polymers and study effect of polymer in
pulsatile drug delivery system.
B. Design and Development of pulsatile release system by using various methodologies.
Direct Compression to form core-in-cup tablets
C. Optimization of Formulation.
5. Evaluation of the formulation Pulsatile Tablets
Thickness
Hardness
PLAN OF WORK 2014

Department of Pharmaceutics, Arya College of Pharmacy, Jaipur (Raj.) Page 3

Weight variation
Friability
Assay
Swelling index
In-vitro drug release study
In-vitro buoyancy study
6. Stability studies of the formulation.
Accelerated and long term stability study
7. Analytical Methods:
A. UV/VIS Spectroscopy
B. HPLC Assay
8. Result and discussion.