Synthetic Blood

Presentation
Brought to you by Hill-Do-Osele Incorporated

Home
(WATCH the video & ANSWER the Following Questions)
1. Every
_ seconds, someone in the U.S. requires blood.
2. Human blood is available, but may be contaminated with ________ or ______________
3. What was the doctors name? _________________ Where was he from? ______________
4. What are stem cells?
BONUS!
What was the initial news anchors name?
What was the TV station?
When does the show air?

History/Intro
1. Ever since
, many people tried to use fluids such as beer,
as a blood substitute.

, milk, and

2. In 1930,
, a physiologist at State College of Medicine in Memphis,
Tennessee, took red blood cells from cows and stripped away the cells' coating,
leaving the
. This was the first published trial. It revitalized patients
but in about 10 days the small HBOC (Hemoglobin-based Oxygen Carriers) molecules
cause
failure.
3. Free hemoglobin was found to be
to the kidneys, so hemoglobin was
modified by cross-linking, or recombination.

Potential Techniques
4. Recently scientists have tried to find a way to use
to create a blood
substitute. A way some studies found was by using
stem cells
removed from umbilical cord between the mother and fetus of humans after birth
using a method called blood
.

5. In 2007, scientists from the Chemistry Department of the University of

Sheffield created artificial blood from
. Unlike donated blood which has a
_______
of
days, the artificial blood lasted longer without the need for
refrigeration. The "plastic" blood consists of an iron-containing_________
which is
permanently bonded to a
(HBP or dendrimer) "shell" which
protects the fragile porphyrin.
6. Reintroducing the hemoglobin into a patient's blood supply using synthetic blood
proves to be an effective
, at least temporarily. In one case where red
blood cells from a cow's stomach are
to perform the
function of blood, the process resulted in
. At first it revitalized
patients, but, in about 10 days, the small HBOC molecules caused kidney failure.

Video
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2. Why are Oxycite Particles so small?
3. The key to salvaging brain tissue is
4. What was the doctors name in this video?