Professional Documents
Culture Documents
Sleep 01 01
Sleep 01 01
and Society
Class Overview
Ralph Lydic, Ph.D.
Burt La Du Professor Emeritus, University of Michigan
Robert H. Cole Professor of Neuroscience,
Psychology & Anesthesiology, University of Tennessee
- Historical Overview:
Brainstem & Forebrain
- Molecules Regulating Wake
and REM sleep: monoamines,
acetylcholine & GABA, orexin
- NREM Sleep: GABA, adenosine
Lotka-Volterra
Y = LC/DR REM OFF
X represents REM ON
X(t) = aX - bXY
Y(t) = -cY + dXY
1989:
1993:
1996:
2001:
2010:
2013:
Treatment of Insomnia
J. Todd Arnedt, Ph.D., University of Michigan
Learning Points:
- Drug and non-drug options are effective
for treatment of insomnia.
- Drug treatments work more rapidly, but
non-drug treatments have better longterm outcome.
- Opportunities for research
Citations
Credit: NASA Earth Observatory/NOAA NGDC
"Insomnia" by Karli M. is licensed under CC BY 2.0
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