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    Juhi Neogi
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    This document contains figures and diagrams related to protein structure, including molecular structures of primary, secondary, tertiary, and quaternary protein structure. The figures show alpha helices, beta strands, molecular bond distances, Ramachandran plots, and molecular structures from protein data bank files for alcohol dehydrogenase, carbonic anhydrase II, and the central stalk of bovine F1-ATPase. Credit is given for the source of the molecular structures.

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    This document contains figures and diagrams related to protein structure, including molecular structures of primary, secondary, tertiary, and quaternary protein structure. The figures show alpha helices, beta strands, molecular bond distances, Ramachandran plots, and molecular structures from protein data bank files for alcohol dehydrogenase, carbonic anhydrase II, and the central stalk of bovine F1-ATPase. Credit is given for the source of the molecular structures.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    6 views25 pages

    2.1.2 Storyboard Launch

    Uploaded by

    Juhi Neogi
    This document contains figures and diagrams related to protein structure, including molecular structures of primary, secondary, tertiary, and quaternary protein structure. The figures show alpha helices, beta strands, molecular bond distances, Ramachandran plots, and molecular structures from protein data bank files for alcohol dehydrogenase, carbonic anhydrase II, and the central stalk of bovine F1-ATPase. Credit is given for the source of the molecular structures.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 25

    THVLPFEKINEGFDLLRSGESI

    Primary

    Quaternary

    Secondary

    Tertiary

    +
    Condensation
    reaction

    2
    3
    .
    1

    Trigonal
    Tetrahedral

    C
    C-N ~ 1.45 > 1.32 > C=N ~ 1.27

    O
    C

    N
    H

    R1

    C
    C

    R2

    trans
    CLASH
    R1
    R2
    N

    cis

    R1

    R1

    R2

    N
    trans

    R2

    trans

    CLASH
    R1
    R2
    N

    R1
    C

    R2
    cis

    cis

    180

    !(psi)

    isoleucine!
    0

    -180
    -180

    !(phi)

    180

    !(psi)

    180

    -180
    -180

    !(phi)

    180

    !(psi)

    180

    -180
    -180

    !(phi)

    180

    !(psi)

    180

    -180

    !(phi)

    180

    n+4

    !(psi)

    180

    -180

    !(phi)

    180

    !(psi)

    180

    -180

    !(phi)

    180

    !(psi)

    180

    -180

    !(phi)

    180

    !(psi)

    180

    -180

    !(phi)

    180

    180

    !(psi)

    -180
    -180

    !(phi)

    180

    N C

    !
    180

    !(psi)

    !
    0

    -180

    N N
    0

    !(phi)

    180

    !
    180

    !(psi)

    !
    0

    C
    -180

    !(phi)

    180

    !
    180

    !(psi)

    !
    0

    -180

    !(phi)

    180

    !
    180

    !(psi)

    !
    0

    -180

    !(phi)

    180

    180

    !(psi)

    -180
    -180

    !(phi)

    180

    180

    !(psi)

    -180

    !(phi)

    180

    THVLPFEKINEGFDLLRSGESI

    Primary

    Quaternary

    Secondary

    Tertiary

    Image credits:

    All molecular structures were created from copyright-free PDB files available at www.pdb.org.
    The PDB identifier of each file, and the original reference, are provided here for scholarly
    purposes.

    Alcohol dehydrogenase: PDB ID 1ADC

    Li H, Hallows WH, Punzi JS, Pankiewicz KW, Watanabe KA, et al. (1994) Crystallographic
    studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate
    binding in two ternary complexes. Biochemistry 33: 1173411744.

    Beta strands: PDB ID 1CA2

    Eriksson AE, Jones TA, Liljas A (1988) Refined structure of human carbonic anhydrase II at 2.0
    A resolution. Proteins 4: 274282. doi:10.1002/prot.340040406.

    Alpha helices: PDB ID 1E79

    Gibbons C, Montgomery MG, Leslie AG, Walker JE (2000) The structure of the central stalk in
    bovine F(1)-ATPase at 2.4 A resolution. Nat Struct Biol 7: 10551061. doi:10.1038/80981.

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