FORMULAS

SALINE NAS
IRRIGATION

By: Kelompo

Introduction

While some amount of mucus production from

the nasal and sinus lining is normal, allergies
and sinus infections can cause excessive mucus
production. This excessive mucus production
causes nasal and sinus symptoms such as a
runny and stuffy nose or post-nasal drip. The key
to symptom relief is to physically wash away this
excess mucus and allergens, such as grass and
tree pollen, dust particles, pollutants and
bacteria from the nasal passages. This rinsing
will reduce inflammation of the mucosa
membrane, allowing you to breathe more
normally.

Rhinitis
The prevalence of allergic rhinitis has steadily
increased in developed countries since the
industrial revolution and now affects 20-40%
of the population. Studies suggest that
allergic rhinitis israre in infants but are
estimated to affect around one in six children
aged 6-7 years, one in ten children aged 1314 years, 18% of those aged 15-34 years and
10% of older adults aged 35-54 years. AR is
more ommon than asthma and chronic
rhinosinusitis.

Anatomi Hidung

Anatomi Hidung
Penderita Sinusitis

Rancangan Formula

Tiap 10 ml larutan irigasi hidung mengandung

NaCl

NaOH/HCl 0.1 N

Purified water

3%
adjust pH 5,5
ad 10 ml

No

Bahan

Kegunaan

NaCl

Bahan
pengisotonis

NaOH/HCl 0,1 N

Pengatur pH

Asam borat

Buffer

Natrium Borat

Buffer

Purified water

Pelarut

Jumlah/wad
ah

Jumlah/batc
h

Alasan Pemilihan
Bentuk Sediaan

Alasan pemilihan
bahan tambahan

NaCl

Untuk sediaan parenteral dan

nonperanteral khususnya sebagai zat
pengisotonis

NaOH/HCl 0,1
N

Buffer Borat

Purified
water

Perwadahan

Cara kerja

Terima kasih