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  • Mar. Drugs 2014, 12 (8), 4361-4378 Doi: Received: 24 April 2014 / Revised: 24 June 2014 / Accepted: 9 July 2014 / Published: 31 July 2014

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    Marine sponges are a rich source of bioactive compounds with potential pharmaceutical applications. This study identifies and characterizes a new diterpene from the sponge Amphimedon viridis that shows selective toxicity against cancer cell lines. In laboratory experiments, the compound inhibited the growth of breast, lung, and central nervous system cancer cell lines, while showing low toxicity against non-cancerous cells. Further research is needed but these results suggest the compound may have applications as a potential anti-cancer drug.

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    Marine sponges are a rich source of bioactive compounds with potential pharmaceutical applications. This study identifies and characterizes a new diterpene from the sponge Amphimedon viridis that shows selective toxicity against cancer cell lines. In laboratory experiments, the compound inhibited the growth of breast, lung, and central nervous system cancer cell lines, while showing low toxicity against non-cancerous cells. Further research is needed but these results suggest the compound may have applications as a potential anti-cancer drug.

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    6 views1 page

    Mar. Drugs 2014, 12 (8), 4361-4378 Doi: Received: 24 April 2014 / Revised: 24 June 2014 / Accepted: 9 July 2014 / Published: 31 July 2014

    Uploaded by

    Yhugho Bng
    Marine sponges are a rich source of bioactive compounds with potential pharmaceutical applications. This study identifies and characterizes a new diterpene from the sponge Amphimedon viridis that shows selective toxicity against cancer cell lines. In laboratory experiments, the compound inhibited the growth of breast, lung, and central nervous system cancer cell lines, while showing low toxicity against non-cancerous cells. Further research is needed but these results suggest the compound may have applications as a potential anti-cancer drug.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 1

    ues Neves Gonalves, Aline Brito de Lima, Maria Cristina da Silva Barbosa, Luiz Fernando de

    Camargos,Jlia Teixeira de Oliveira, Camila de Souza Barbosa, Jos Augusto Ferreira Perez
    Villar, Andr Carvalho Costa, Isabella Viana Gomes da Silva,Luciana Maria Silva, Fernando de Pilla
    Varotti, Fabio Vieira dos Santos and Gustavo Henrique Ribeiro Viana
    Mar. Drugs 2014, 12(8), 4361-4378; doi:10.3390/md12084361
    Received: 24 April 2014 / Revised: 24 June 2014 / Accepted: 9 July 2014 / Published: 31 July 2014
    Show/Hide Abstract | Cited by 1 | PDF Full-text (870 KB) | HTML Full-text | XML Full-text

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