3

GROU
P

ENDOCRINOLOG
Y
a medical approach to reproductive hormones
DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA IUNIVERSITY OF THE IMMACULATE
BACHELOR OF MEDICAL LABORATORY SCIENCE
PAGUNSAN
CONCEPTION

3
a
bout
TALK
progesteron

LETS

GROU
P

ENDOCRINOLOG
Y
a medical approach to reproductive hormones

UNIVERSITY OF THE IMMACULATE

DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA I
BACHELOR OF MEDICAL LABORATORY SCIENCE
PAGUNSAN
CONCEPTION

ENDOCRINOLOG
PROGESTERONE: the insid
Y

LETS

Structure and Functions

TALK

Hormone Synthesis

about
progesteron
e

Pathologic condition
Laboratory Test

Treatment and Management

Summary

UNIVERSITY OF THE IMMACULATE

DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA I
UNIVERSITY
OF THE
IMMACULATE
BACHELOR
OF MEDICAL
LABORATORY
SCIENCE
PAGUNSAN
CONCEPTION
BACHELOR OF MEDICAL LABORATORY SCIENCE

mens
es

FOLLICULAR PHASE

FSH and LH interacts during the

menstrual cycle

FSH is inhibited by high levels of

estrogen; LH is inhibited by low levels of
estrogen
FSH acts on the development of follicle
that will be dominant during the next
cycle

mense
s
Core reaction

cholesterol

testosterone estradiol

progesterone17-hydroxyprogesterone

androstenedione

pregnenolone

17-hydroxypregnenolone
dehydroepiandrosterone

estrone

CORPUS LUTEUM

THECA CELLS

GRANULOSA CELLS

endocytosi
cholesterol
s

Inside the ovar

synthes
is
glucocorticoids

granulosa cell

mineralocorticoid
sgonadal steroid

lipoprotei
n

Enzymatic
reaction

luteinizing
hormone
Cholesterol cleavage enzyme

cholestero
l

3B-hydroxyl-steroiddehydrogenase

pregnenolone

progesterone

Further converted to
other product

Inside the
cell

progesterone

used in the reproductive

system for cell activities

progesterone

Up next

GONADAL STEROID
DISEASES &
DISORDERS
Ms Shaira Edit
Department of Clinical Chemistry
Endocrinology Section