Scientist(s)

Thucydides
Lady Montagu (British Ambassador)
Edward Jenner
Neisser
Louis Pasteur (Founder of Immunology)
Elie Metchnikoff
Klebs and Loeffler
Roux and Yersin
Emil von Behring and Shibasaburo Kitasato
Almroth Wright and S.R. Douglas
Paul Ehrlich
Charles Richet and Paul Porter
Clemens von Pirquet and Bela Schick
Karl Prausnitz and Heinz Kustner
Riley and West
Karl Landsteiner
Haurowitz
Niels Jerne and McFarlane Burnet
Dausset and Rapaport
Claman
Milstein and Kohler

Contribution(s)
Bubonic plague those who had the disease
could nurse patients and would not contract it
again
Introduced variolation
*Variolation introduction of materials from
lesions to induce resistance
Vaccination (from vacca=cow)
Isolated first human pathogen, Gonococcus
Chicken cholera vaccine
Anthrax vaccine
Rabies vaccine
Cellular Phagocytic Theory of Immunity or Cellmediated Immunity
Isolated diphtheria bacilli
Produced first defined antigen (diphtheria toxin)
Humoral Immunity
Immune response is both cell-mediated and
humoral
Opsonins
Standardization of diphtheria toxin and antitoxin
preparation
Phenomenon of prophylaxis
Anaphylaxis is both beneficial and damaging
Serum sickness
Allergies can be transmitted
Histamine is present in mast cells
ABO Blood group system
Template Theory of Antibody formation
Clonal Selection Theory
HLA (Human Leukocyte Antigen)
T-cells and B-cells work together in an immune
response
Hybridoma for the production of monoclonal
antibodies

IMMUNOLOGIC METHODS
Immunologic Method(s)
Complement Fixation
Passive Hemagglutination
Rosette Formation
Plaque Formation by Immunocompetent Cells in
Agar Gel
Use of Abs or Ags Labelled by Fluorescent

Discoverer(s)
Bordet and Gengou
Boyden
Biozzi and Zaalberg
Jerne, Henry and Nordin
Coons

Compound
Use of Abs or Ags Labelled by Enzymes
Avrameas and Uriel
Use of Abs or Ags Labelled by Radioactive
Yalow and Berson
Elements
Precipitation in Gelled Media
Ring test (disk test)
Bechold