Patients Initials: IBL

EMILIO AGUINALDO COLLEGE

Age: 2 years Old
School of Nursing and Midwifery
DOB: 2-13-15
1113-1117 San Marcelino St. Ermita Manila
Dx: Closed comp. disp. Subtroch
Right Femur

Miguel S. Datijan
EAC 3rd Year BSN

Name of Drug
Generic Name:

Classification
Pharmacologic Class:

Mechanism of Action
Therapeutic:

Indication
General Indication:

Ranitidine

Gastrointestinal agent:

Competitive inhibition of

Used to prevent ulcer

Trade/Brand Name:

Antisecretory (H-2 receptor

histamine at H2

while patient is on NPO

Zantac

antagonist)

receptors of the gastric

Patients Dose: 10 mg

Pregnancy Risk

parietal cells which

(For Pediatric)

Category:

inhibits gastric acid

maximum: 300 mg /

Pregnancy Risk B

secretion, gastric volume

day

and hydrogen ion

Availability: 2-4 mg/kg

concentration are

per day in two divided

Source:www.unilab.com

reduced. Does not affect

doses

pepsin secretion,

Route(s) of

pentagastrin stimulated

Administration: Oral,

intrinsic factor secretion,

Parenteral: IM, IV

or serum gastrin

Source: nurseslabs.com
Pharmacokinetics:
Onset: 30 minutes
Peak: 1-3 hours
Duration: 6-8 hours
1 |EAC

Drug Study Form

lav-m2013

Contraindication
Contraindication:
H2-blockers may be
contraindicated in : Renal disease,
hepatic disease: the H2-blocker
may build up in the bloodstream,
which increases the risk of side
effects. Immunodeficiency :

Side Effects
Drowsiness
Dizziness
Decreased Sex drive,
impotence or difficulty
having an orgasm
Swollen or tender breasts (in
men)
Stomach pain

Nursing Responsibilities
* Inform patient that the
medication may cause
drowsiness, dizziness or fatigue
(Use caution when driving or
engaging in task requiring
alertness)

Decrease in stomach acidity

caused by H2-blockers may

* Inspect patients to avoid taking

increase the risk

Drug to Drug Interactions:
Aminophylline, Anticoagulants,
Caffeine, Metoprolol, Oxtriphylline,
Phenytoin, Propranolol,
Theophylline, Tricyclic
antidepressants (amitriptyline,
amoxapine, clomipramine,
desipramine, doxepin, imipramine,
nortriptyline, protriptyline ) : these
2 |EAC

Drug Study Form

lav-m2013

Adverse Effect
Constipation
Diarrhea
Fatigue
Headache
Insomnia
Muscle pain
Nausea
Vomiting
Agitation
Anemia
Depression
Easy bruising or bleeding

any new medication during

therapy without consulting
prescriber
* Inspect patient to avoid alcohol
and follow diet as prescriber
recommends

drugs when used with ranitidine

have been shown to potentiate the
effects of ranitidine. Itraconazole,
Ketoconazole : H2-blockers may
decrease the effects of
itraconazole or ketoconazole,
hence H2-blockers should be taken
at least 2 hours after these drugs.

3 |EAC

Drug Study Form

lav-m2013