Stayed 1 day only in the hospital

Kawasaki disease (KD), formerly known as mucocutaneous lymph node syndrome and infantile polyarteritis nodosa

01/26/16

High fever higher than 390C and many cases above 400C. Fever persist for a mean of 11 days w/o treatment
-fever usually resolves w/n 2 days of tx
-within 2-5days after onset of fever, principal features developed
Desquamation of the hands and feet takes place w/n 2-3wks

Conjunctivitis occurs shortly after onset of fever. Resolves rapidly.

Rash usually appear w/n 5 days of onset of fever and take many forms
most common nonspecific diffuse maculopapular eruptions
distributed extensively, involving the trunk and extremities, with accentuation of perineal region where
early desquamation occur

Changes in lips and oral cavity

Oral ulcerations and pharyngeal exudates are not seen
Cervical lymphadenopathy is the least common of principal feature in approx. 50% of patient
01/26/16

Firm swelling is unilateral involves more than 1 node measuring >1.5cm confined to anterior cervical triangle

lasts until about the fourth week, is characterized by gradual resolution of fever (if untreated) and other symptoms.
Desquamation of the skin, particularly of the fingers and toes, appears at this point. The platelet count, previously
normal or slightly elevated, increases to a significant degree (often >1 million/mm3). This phase heralds the onset of
coronary artery aneurysms, which usually appear in the subacute and convalescent phases, and pose the highest risk
of sudden death. Risk factors for development of coronary artery aneurysms include prolonged fever, prolonged
elevation of inflammatory parameters such as the ESR, age younger than 1 year, and male gender.

aspirin + other anti-platelet (Dipyridamole, Clopidogrel)

more effective in suppressing platelet activation