Konelab

www.thermo.com/konelab

KONELAB
:

6.0

5.4.2004

D01626

Thermo Electron Oy

Ratastie 2, P.O.Box 100

FIN-01621 VANTAA
: +358 9 329 100
Fax: +358 9 3291 0500
www.thermo.com/konelab


,

1.
2.
2.1
2.2
2.3
2.3.1 Konelab 60 Konelab 30
2.3.2 Konelab 20XT Konelab 20

2
2
3
4
4
5

3.

4.

10

5.

13

13
5.1
5.2
5.3 ISE Prime Start up
5.4
5.5 /QC
5.5.1
5.5.2 QC
5.6 ,

5.7
5.8 QC
5.8.1
5.8.2
5.9
5.9.1
5.9.2

5.9.2.1
5.9.2.2
5.9.2.3
5.9.3

5.9.4 STAT
5.9.4.1 STAT

5.9.4.2 STAT

5.9.4.3 STAT
5.9.4.4
STAT
5.10
5.10.1
5.10.2 /
5.11
5.11.1 LIMS
5.12 Stand by
5.13
D01626

25.11.2003

14
14
15
16
17
17
18
20
20
21
21
23
25
25
27
27
30
34
37
38
38
38
39
39
40
40
42
44
46
47
48
I

5.14
5.14.1
5.14.2

6.

50
50
52

53

6.1
6.2 ,
6.2.1


6.2.2
6.2.3
6.2.4

6.2.5
6.2.6
6.2.7

53
54
54
54
54
54
55
55
56

Copyright 2003 Thermo Electron Oy. .

.

Konelab Thermo Electron Oy.

Thermo Electron Oy
.

D01626

25.11.2003

II

CE Konelab
IVD (
in vitro) 98/79/EC.

FCC

,
15 FCC.

. ,
,
,
. ,
.
,
,

:
- .
- .
-
.
-
.

in vitro

D01626

08.01.04



2
3

:
,
.

.
.
:

3

.





.

D01626

:
Kusti
.


Kusti.

08.01.04

:
.
.

.

:
.
.

D01626

25.11.2003

II

: ,
Konelab 60 KUSTI, .
.
1) ,
ON (I),
, on.
5.14.2.
2) stand by
,
PC
. ,
, , off.
,
.
-
,
.
PC
stand by
.

D01626

25.11.2003

III

: .

PC UPS (
)
XP PC
.

D01626

08.01.04

IV

1. TOY
Konelab in
vitro

, , ,
.

Konelab 60 & Konelab 30

G
B
A

E
F

.
B.
C.
D.

D01626

25.11.2003

E.
F.

G.

,
KUSTI

 Konelab

Konelab 20XT & Konelab 20

C
A
D

A. / STAT
B.
C.
D.
.

2.
2.1

:

enter tab

, shift tab
.

:


.
/ ,
.

D01626

08.01.04

 Konelab

/:

, ..
.
.
.
.
STAT.
, ..

* .

!
*

F9

/
.

F10

F11

F12

2.2

D01626

- Start
()

START
()
.

.

- Stop
()

STOP
()
.

START ().

25.11.2003

 Konelab

2.3

2.3.1 Konelab 60 Konelab 30

. :
(LA) ,
.
LED ,


.

B. STAT:

(LB)
STAT.
STAT.

,
STAT.

       
    .
    ./   .

LA
B
A
LB

C. :
(LC) ,
.
LED ,


.

LC

D01626

25.11.2003

 Konelab

D. :
(LD)
.
.

,
.

2.3.2 Konelab 20XT Konelab 20

E. /
Stat:

Konelab 20XT 20
, F2
/ .

D01626

25.11.2003

 Konelab

(LE) .
/ STAT.

,
. .

LE

STAT
F5, Insert stat sample ( stat)
/.

(LE) .
/ STAT.

,
STAT. .

D01626

25.11.2003

 Konelab

F. :
(LF) ,
.
LED ,


.

LF

G. :
Konelab 20XT
20 . F2
Reagent disk ( ).

D01626

25.11.2003

 Konelab

(LG) .
.
,
(G)
. .

LG

.
.
.

3.

Start up.






.

D01626

H
N
J

I
K

: (..
, ..) ..
Cuvettes ()
.

25.11.2003

 Konelab

C
D

:
,
.
:
.
/ :

/. STAT
/.
:
. , .
,
, STAT,
,
.
:
.

G
H
I

:

.
:
.
:
.
: , ..
,

.
,
MESSAGES () ,
.

,
.

: .
.

:
- In process ( ): .
- Ready () ( ):
.
- Not started ( ) ( ):

.
- In loader ( ):
.
- Check data ( ) (
): .
- Discarded segment ( ) (
):
.
F9 F8/F5 . F3,
.
STAT:
STAT. .

.
.

D01626

25.11.2003

 Konelab

:
(C, D, F, G, H, I K).
(L, M N).
- (C, D, F, G, H, I K)
, .. F10
TEST RESULTS ( ).
(L, M N), .. F9
F8/F6 SAMPLE SEGMENT (
).

4.

- Batch entry
( )

- Configuration
()

Configuration (),
..
. ..
:
,

/,
:
ISE
.

- LIMS configuration
( LIMS)

- Management ()

QC .

- User management
( )

- Restrictions ()

- Messages ()

- Profile definition
( )

- Reagent definition
( )

- Reagent disk (
)

.


.

D01626

25.11.2003

10

 Konelab

- Reference class definition

(
)

- Reports ()

- LIMS connection
( LIMS)

online.

- Sample disk (
)

- Sample/ Patient entry

(
/)

/ .
(
)
.

/
.

- Sample list (
)

- Sample/ Patient results

(
/)

/. ,
, .

- Sample segment
( )

14 .

- Pending requests
( )

- Sender definition
( )

,
/ .

- Calibrator & Control

definition (
)

- Calibration parameters
(
)

- Calibration results
(
)

.
.

.

- Calibration/ QC selection
( QC /
)

.

QC .
.

D01626

- Quality control results

(
)

- Results by controls
(
)

25.11.2003

11

 Konelab

- Quality control
parameters (
)

- Test definition (
)

.
.

- Test flow (
)

, , .
.

- Electrodes ()

- Test results
( )

. , ,

.


.

D01626

- External results
( )

- Result archive (
)

- Calibration archive
( )

,
.

- Reagent lot archive

(
)

- Statistics ()

,
.

- Report formats
( )

, .

- Instrument actions
( )

, ..
ISE prime
.
.

- Maintenance
()

.

.

- Accuracy results
( )

,

.

.

25.11.2003

12

 Konelab

- Accuracy factors
( )

D01626

.
.

,
.

25.11.2003

13

 KONELAB

5.

ISE Prime

QC/.

QC.

, .
.

START.
,




.

,
. QC
.

START

Main ()

QC

START
() .
.
Stand by ():
. .
.

D01626

08.01.04

13

 KONELAB

5.1

.
User
manager ( ).

5.2
.
.
.
.
ISE 1
.

:


.



.
.
D01626

25.11.2003

14

 KONELAB

Start up (
).
'Start up
needed' (

)

.




.


.

Start up.






.

START UP,

.

D01626

5.3 ISE PRIME

START UP (
)
.

F1
Start up

. .
Konelab 20XT 20 ISE prime
STAT. Konelab 60 30
ISE prime ,
0,5 2 ml .
START UP ( ) :
.
STAND BY
().

.
START UP ( )
:

.
.
ISE 1 ISE.
ISE
ISE Prime.
.

25.11.2003

15

 KONELAB

5.4

QC

F4.

, Caps
Lock

D01626

. .

. Konelab 60 30,
F8/F1
. F1 .

.
Reagent position (
)
.
.
. ,
.
Konelab 20XT/20, .
.
Konelab 60 30

.
Konelab 20XT 20
, F2 .
.


.
F2
Konelab 20XT/20
.
25.11.2003

16

 KONELAB

F8/F3
.
, ..
. F8/F3
.

5.5
/QC (
)
5.5.1

,

, ..
S1...S19

QC

,

F4

, .

- F2 K20/20XT
.
. K30/60

!

,

Cal/QC
selection (
/
)
.
'Disk pos' (
) ,


.

F6

./.
F1
.

D01626

25.11.2003

17

 KONELAB

QC ( ) (
)
START ().

5.5.2 QC ( )


, ..
C1...C19.

, .

F4

QC

,

, .

F2 K20/20XT

. .
K30/60

!

,

Cal/QC selection
(
/
)
.
'Disk pos' (
) ,


.

F6

./.

F2

. QC

QC (
)
START ().

D01626

25.11.2003

18

 KONELAB

F5 QC ,

.
/ ISE
prime/ Konelab 20XT Konelab 20

F4, Add prime/wash ( prime/)

ISE prime
.
,
STAT .
/
Konelab 60 Konelab 30

F4
/
. .
,
.

/
.
- F3,
. / .


.
D01626

25.11.2003

19

 KONELAB

Konelab 60
30,

./.
.


.

5.6
,

Konelab 20XT 20
STAT.
Konelab 60 30

STAT. ,
./. ,
0,5 2 ml , ,
.
/.
. ,

.

. ./.

Konelab 60 30 ,
.

Konelab 20XT 20 ,
.

5.7
START () .
Main ()
.

D01626

25.11.2003

20

 KONELAB

5.8 QC
( )

5.8.1
. .
F8/F7
.
.
.
F7
.
.

. ../QC
F7
. .

. .

F2 .
, F6.
F3
. .

F5.

D01626

25.11.2003

21

 KONELAB

F5, Delete calibration ( ),

.
, .
:

.




.

,

.

:
.
.
.
- F1
.
. F8/F1 .
- F8/F3
.
- F8/F2 .
.

.
:
CALIBRATION
PARAMETERS ( )
Bias corr. repeat time (
) . 4.4.1.
- F8/F6
.
- F8/F7 .
.

D01626

25.11.2003

22

 KONELAB

5.8.2

QC
(
)

QC

Clear
daily files (
. ).

QC

Clear
daily files

Management
().

. ./QC
F6
. QC

.
F8/F1
. QC

. QC
F1
QC (Display cumulative/ Display results
/ ).
QC:

D01626

QC,
.
SD ( )
.
F6,
.

QC ,
.
SD ( )
.
F6,
.

QC. Mean
QC SD
QC.

25.11.2003

23

 KONELAB

SD

. Z ,

. :
Z = ( QC
)/

.
F2
, .
Result statistics ( ) .

F3
, .
Result statistics ( )
.

F5
.
.

F7
.

D01626

25.11.2003

24

 KONELAB

5.9

5.9.1

/
.

10 mm

.


.




.

Konelab 60 Konelab 30

.

, .

.
.

C .

(F9) .

Konelab 20XT Konelab 20

F2, Insert segment ( )
/ .
.
.
.

D01626

25.11.2003

25

 KONELAB

,
. . C
.

D01626

25.11.2003

26

 KONELAB

5.9.2

,
,

.

5.9.2.1

. .

B
A
P1 ISE
P2 Lipids

D
C
E

.
- Segment ()

D01626

.
(. 16 )
.

F8/F2 .

25.11.2003

27

 KONELAB

,
.

./. Konelab 60 30
.
(QC)
QC/.

C
:

.
-

.
Next request ( )
. P
.
Konelab
ASTM

.
.

. .

STAT.
F7, STAT. !.

,
(
) S. , U-Alb
U/CSF Prot,
U/CSF Prot S.
,
R ( ).

.
.

(1-14)

.
, ..

.
Position ()

.

.
. /
.
F1 .

D01626

25.11.2003

28

 KONELAB

.
/ .
--

F3,
. / .

.

Remove ()
0
. . /

F3 .
F3
.
F3 .

F8/F3 .

F8/F8/F5
, ..
.

C
A
B

D01626

25.11.2003

29

 KONELAB

F8/F8/F1

.
Sample entry
( ),

.

B
C

,
,

Configuration
().

.
1 120 0.5.
D
.

5.9.2.2

. .

B
A

G
E

.
- Segment ()
.

D01626

25.11.2003

30

 KONELAB

(. 16
.
)
F8/F2 .

,
.

./.
Konelab 60 30
.
(QC)
QC/.
.
.
F8/F8/F2 .

:


.
--

.
Next request ( )
.
P .
Konelab
ASTM

.
.
E

.
.
STAT.
F7, STAT.
!.
,
(
) S. ,
U-Alb
U/CSF Prot, U/CSF Prot S.
,
R (
).
.
:

(1-14)

.

, ..

.
Position ()

D01626

25.11.2003

31

 KONELAB

.

.

. /
.

F8/F1 .
.

F1 .

. / .
- F3,
. / .


.

Remove ()
0

. . /
.

D01626

25.11.2003

32

 KONELAB

F3 .
F3
.
F3 .

F8/F3 .

F8/F8/F5
, ..
.

C
A
B

F8/F8/F1

.
Patient entry
( ),

.

.
1 120 0.5.
D
.

D01626

25.11.2003

33

 KONELAB

5.9.2.3

F8/F8/F4
Batch entry

F8/F4
.

.
./
F8/F4
.

.
F7
.

. .
F7
.

F1
.

.
, ..
.

A
D
F

H
G

A
B

(. 9 )
.
F8/F2 .

, .
- Segment ()
.

D01626

08.01.04

34

 KONELAB

.

Position
.
()
.

.
. . , .. 2
9 2.9 .

7






.

- F5
.
Next request ( )
. P
.

Konelab
ASTM

.
.

.

.
, 19 2 , 38 .

F2
.
F3
.

. /
.

. / .

--

F3,
. / .


.

Segment ()
0. . /
.
D01626

08.01.04

35

 KONELAB

F6 .
F6
.
F6 .

A
B
E

C
D

G
D
F
H
A

(. 13 )

.
F8/F2 .


Sample numbers (
.
)
.
1000 .
.
. , .. Srg11
12 Srg11012.

D
:


.
- F5
Next request ( )
. .

P .
Konelab
ASTM

D01626

25.11.2003

36

 KONELAB

.
.
E

.
, 26 2 , 52 .

F2. F3
.

F6
.
F6
.
F6 .

5.9.3


Konelab
KUSTI ,
.

KUSTI Konelab.

KUSTI

KUSTI

KUSTI

.
, .

D01626

25.11.2003

37

 KONELAB

.
.

,
Sample/Patient entry ( /).

5.9.4 STAT
5.9.4.1
STAT
Konelab 60 Konelab 30

STAT
STAT . .
STAT.

.

. .

(F9),
. C
5.9.2.1 D 5.9.2.2.

Konelab 20XT Konelab 20

(F9), F5, Insert stat sample
( stat). .
STAT.

.

, STAT
.
.

Sample/Patient entry (
/) . C 5.9.2.1
D 5.9.2.2.

D01626

08.01.04

38

 KONELAB

5.9.4.2 STAT

(F9),
///,
. 5.9.2.1 B, C E 5.9.2.2
B, D F.
F5, Insert stat sample ( stat).
Konelab 60 30 STAT.
.
STAT.
. Konelab
20XT 20 STAT .
STAT .

5.9.4.3 STAT
STAT



STAT

.

(F9), STAT

F6, Remove STAT sample (

STAT).
STAT Konelab 60 30.
.
STAT.
.
Konelab 20XT 20 STAT .
.

5.9.4.4 STAT

STAT

.
STAT

STAT
. 5.9.1. 5.9.2.

SAMPLE/ PATIENT/ BATCH ENTRY

( //)
F7, STAT, STAT.
!Stat ON
!
, F7 (
STAT off) .
STAT .

D01626

25.11.2003

39

 KONELAB

5.10
5.10.1

. .

:

. .
.

F8/F4
.
- F2 .
F3
.
- F5
. ,
CV ( ) .
- F8/F3
.
- F8/F6
.

D01626

08.01.04

40

 KONELAB

. 1 120 0.5.
.. 9 1+9
1:10.
- F8/F2
. .

- F8/F8/F1 ,
CV ( )
. CV
.

QC

.


.



.

QC
- / Stat

- QC
'Batch incomplete' ( )
- ctrl-stop
- .

. QC
.

QC
QC.
QC, Calibr./QC selection ( ./QC).

F8/F8/F3
.
start () .
, No ()
Test in use ( ) Test definition
( ).

F1 .
.
F8/F1 .
D01626

08.01.04

41

 KONELAB

5.10.2 /

,

,

Configuration
().

F5
.

F5
.

. .

. .

:

. .
.
- F2 .
F3
.
- F5
.
- F8/F3
.
- F8/F4
.

. 1 120
0.5. .. 9 1+9
1:10.
-

D01626

F8/F2 .
.
25.11.2003

42

 KONELAB

F1 .
.
F8/F1 .

D01626

25.11.2003

43

 KONELAB

5.11
.
F4

LIMS
F4

A
B

C
D

D01626

:
- ,
-
- .

/ :
- . ,
- ( ),
- ( ,
),
- ( ).

:
- ,
-
- .
:
-
- .

25.11.2003

44

 KONELAB

F2
//.

F3 .
F4, Daily report ( )
.
,
.
.

Excel
F8/F4 excel.
excel C:\Konelab\Results.

-
.
-

(, ).
.

(. 30 ).

.
.

D01626

25.11.2003

45

 KONELAB

5.11.1 LIMS

LIMS

ASTM,

F5
LIMS

LIMS

B
F
A

F1
.

: .

F3, Send results ( ).

: .

F2, .

F5 LIMS
.
D01626

25.11.2003

46

 KONELAB

5.12
.

F2
Stand by

Stand by

.

ISE Prime ./ Konelab 60
30.

KUSTI
KUSTI.

STAT Konelab 20XT 20.
STAND BY :

D01626

, ISE, KUSTI
.
.
.

25.11.2003

47

 KONELAB

5.13
.
F8/F3

F7

F7
.
/
/.
QC ,
, ,
.
.

F2
.
.

8000
(

)


10000.

D01626

F
F

F5
. .

F6 CD.
.
CD Configuration ().

F8/F6
. ,
, , , ,
..
F7.
.
.
08.01.04

48

 KONELAB

F1 .
F4 About ()
Konelab ,
PC Konelab 60 30.
F8/F3 Konelab
.

1. .

QC
QC
. QC,

. =
.
KONELAB

QC
. QC

QC

/
/ .

D01626

/ /

( )

( )

08.01.04

49

 KONELAB

5.14

!
PC

5.14.1

Konelab Management
() F8/F3.

( Start: Shut down (:

) ).
.

Konelab
OFF .

D01626

01/03/2004

50

 KONELAB

Konelab 60 KUSTI

Konelab 60 KUSTI

,
, stand by


.
stand by,
PC
.

,
.
:

PC
stand by
.

D01626

25.11.2003

51

 KONELAB

5.14.2

Konelab
20XT/20,

Konelab 20XT/20,
PC!

( domain Konelab
Konelab).
Konelab .

Konelab
ON
Konelab.

Konelab 60 KUSTI

Konelab 60 KUSTI,
,
ON (I). ,

.

D01626

29/03/2004

52

 KONELAB

6.

6.1

,

QC.

F8/F7

F8/F7

Maintenance ()
.
.
A

.
F1 .
.

.

F2. F3
.

D01626

08.01.04

53

 KONELAB

F4
. .
*
, .. .

Clinical
Chemistry &
Automation
Systems
business
Thermo

6.2

!

5060%


.

6.2 , &

6.2.1




.
STAND BY.
.

F8/F4 Clean needles ( )

Instrument actions ( ).
,
.
,
.

(4,5%
) 50-60% .
.

6.2.2

.
50-60%.

6.2.3

. .
.

6.2.4

(50-60%)
/ .
, ,
(50-60%) . T
(Trihydrate) 99%
.
D01626

08.01.04

54

 KONELAB

6.2.5

.
Start up ( )

. ,
.

)
)

Konelab Management
() F8/F3.
( Start: Shut down (:
) ).
.

)
)

( domain Konelab
Konelab).
Konelab .

FMI


.

brij,

D01626

6.2.6

. FMI .

)
)

100 ml (1:5) (=4,5%

, 980929)
.
Konelab 60, 150 ml
.

Instrument Actions F6 (
), Perform water wash ( ).

( K60 700 - 850 ml K30
350 450 ml K20XT/ 20 300 350 ml)
, Perform water wash 5 - 6
.
,
.

Perform water wash 2 3 .

29/03/2004

55

 KONELAB

6.2.7

F
F
F

.
Stand by .

T .
.

(4,5% )
50-60 %.

D01626

08.01.04

56