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Hypertrophy
The Prostate
Pyramidal shaped, fibromuscular, and
glandural organ.
Walnut-sized gland, 3cm long.
Located anterior to the rectum, distal to
the urinary bladder.
Zones of Prostate
Definition and
Epidemiology
Benign prostatic hypertrophy or
hyperplasia (BPH) is a histologic
diagnosis characterized by proliferation
of the cellular elements of the prostate.
Incidence
>50% in men between 60-90 y.o
30 million men worldwide have
symptoms related to BPH.
Pathophysiology
Development of microscopic stromal
nodules around periurethral
glands glandular hyperplasia gland
increases in size and compresses the
urethra urinary obstruction.
Uncertain aetiology multifactorial,
hormonal (?).
Investigation
Physical Examination
Bladder distension
Sensory and motor deficits
Rectal toucher : gland size
Management
Non-surgical treatment
-adrenergic blockers
Antiandrogens acting selectively at
prostatic cellular lebel
Intermittent self-catheterization
Balloon dilatation and stenting of
prostate
Surgical treatment
Prostatectomy
TURP
Thank You.