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NEJM 22/03/2016
1. In an asymptomatic patient, both stenting and carotid endarterectomy are
equally efficacious and carries equal rates of MI, death or subsequent ipsilateral
stroke over a 10 years of follow-up.
2. Scabies is characteristically worse at night. (Recall) Can secondarily lead to
imperigo, ecthyma, paronychia or furunculosis. Clinically, burrows are difficult to
visualize and may be disguised by excoriations and impetigo.
3. Causes of Interstitial lung disease: (5-CDSIO) Connective tissue diseases,
Disorders related to occupational, avocational, environmental or medication
exposure, Sarcoidosis, Idiopathic causes, Others.
I.
Disorders related to occupational, avocational, environmental, or medication
exposures (e.g., hypersensitivity pneumonitis)
II.
Connective-tissue diseases (e.g., scleroderma, rheumatoid arthritis,
dermatomyositis, polymyositis, Sjgrens disease)
III.
Sarcoidosis.
IV.
Idiopathic causes (e.g., idiopathic pulmonary fibrosis, nonspecific interstitial
pneumonitis, respiratory bronchiolitisassociated interstitial lung disease,
desquamative interstitial pneumonitis, cryptogenic organizing pneumonia,
acute interstitial pneumonitis)
V.
Other causes (vasculitis, diffuse alveolar hemorrhage, Langerhans-cell
histiocytosis, chronic eosinophilic pneumonia, lymphangioleiomyomatosis).

4. Hypersensitivity pneumonitis caused by an immune response to inhaled


proteins. I.e: farmers lung, bird-fanciers lung, hot-tub lung and shower-curtain
disease. Ix: CT Thorax nodules, ground-glass opacities, air trapping, reticular
changes and in chronic cases, fibrosis. Tx: avoidance of offending agent, steroids
severe sx.
FA 2016 - Mixed type III/IV hypersensitivity reaction to environmental antigen
dyspnea, cough, chest tightness, headache. Often seen in farmers and those
exposed to birds.
5. Organizing pneumonia Hx: several weeks of prodromal constitutional
symptoms, followed by the abrupt onset of cough and dyspnea. Ix: Imaging patchy migratory pulmonary infiltrates, possibly with ground-glass opacities and
consolidation with air bronchograms. Etio: primary or 2 to drug reactions,
cocaine use, collagen vascular diseases, hypersensitivity pneumonitis, infection,
cancer, organ transplantation, infarcts, tumors, necrotizing granulomas,
radiation, therapy, toxic-fume exposure, and smoke, inhalation. Tx: Steroid at
least 1 year.

6. Froin syndrome: pathognomonic - elevated protein, xanthochromia, and


hypercoagulation of CSF. Etio: Blockage of CSF flow by a spinal cord mass or
with meningeal irritation from meningitis.

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