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ESTERIFICATION AND HYDROLYSIS WORKSHEET

1. Complete each of the following esterification reactions.


HO

O
H+

OH
O

Alcohol

acid

O
H+

HO

OH

Alcohol

acid
A cyclic ester (a lactone).

1. Circle the ester bond in each of the following reactant molecules.


2. Draw the structures of the products for each of the following reactions.
O

O
C H3

H+/H2O

O
H3 C

CH2
O

C H3

+ NaOH/H2O

HO

HCl/

O
P
OH

P
O

+ 2NaOH/H2O

O
O

HO

OH

OH

H2O

FATTY ACID ESTERIFICATION AND LIPID HYDROLYSIS WORKSHEET


1. Complete the following esterification reaction.
2. Write the names of the reactants under the structures (look up fatty acid names on handout).
3. Write the name of the product or the classification of lipid in each of the following reactions.
CH2OH
3

COOH

CHOH

H+

CH2OH

1. Circle the amide or ester bond in each of the following reactant molecules. Amides are hydrolysed
just like esters, except an amine instead of an alcohol is produced.
2. Draw the structures of the products for each of the following reactions.
3. Write the name of the fatty acid products.
+
N(CH3)3
o2c

+ NaOH/H2O

CO2

HO

CH

CH N

O
O

CH=CH(CH2)12 CH3

+ 3NaOH/H2O
O

CH2

O
+
CH2 CH2 N(CH3)3

CH2
CH
CH2

O
CH2

CH3
16

O
O

CH2

18

CH3

HCl/
H2O

O
CH3(CH2)29OC (CH2)14CH3

+ NaOH/H2O

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