Disposition
Animal Information
Name
Gender
| Species
Date of ith if known)
Date Acquired
Source
| Disposition Information
Died or Euthanized
Necropsy performed (y/n)
Cause of Death
All medical records pertinent to an animal must be maintained for the duration of the
animal study period plus 3 years after the animal's final disposition.
Medical Record
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Fam WADDLOOTa Venn ooWASHINGTON ANIMAL DISEASE DIAGNOSTIC LABORATORY
P.O, Box 647034
Pullman, WA 99164-7034
Phone: (509) 335-9696
Fax: (509) 335-7424
Veterinarian: Dr. GayLynn Clyde Owner: Charles Robbins
Clinic: OCV Animal: Roan
Address: Office Campus Veterinaria Species: Brown Bear
Breed:
Pullman, WA. 99164-1165 Age: 5 Years
Phone: (509) 335-8035, Sex: Male
HISTOPATHOLOGY REPOR' 02/05/16 WADDL #2016-960
Report authorized by: Josh David Ramsay, Senior Pathologist Received: 01/26/16
Diaphragm mass: Grossly, a 3 cm’, moderately firm, pale tan mass expands the fascia on the diaphragm.
Histologically, the mass is composed of haphazard, loosely arranged spindloid to stellate cells surrounded
by a 1 mm thick collagenous capsule. Scattered, small clusters of macrophages distended with
homogenous yellow or granular brown material (hematoidin and hemosiderin, respectively) infiltrate the
periphery of the mass.
‘Thyroid gland: Grossly, a small, encapsulated pale tan nodule adjacent to the trachea exudes abundant
thick pale tan liquid on cut section. Histologically, the thyroid gland is focally disrupted by an expansile
cyst lined by a keratinized stratified squamous epithelium and supported by mature collagen. Clusters of
lymphocytes and plasma cells dissect between collagen fibers adjacent to the cyst.
Small intestine: The lamina propria is mildly expanded by lymphocytes and plasma cells that multifocally
lift and separate intestinal crypts.
\diserete vacuoles
Liver: Diffusely throughout all sections of liver, hepatocytes contain multiple, small,
(hydropic degeneration).
Spleen: The splenic red pulp is expanded by sheets of erythrocytes (congestion).
Tissues examined and considered normal include the trachea, lungs, heart, liver, gallbladder, bile duct,
kidneys, spleen, lymph node, stomach, large intestines, pancreas, and bone marrow
HISTOLOGIC DIAGNOSES:
1. Nodular fibroplasia, focal, mild; diaphragm.
2. Ultimobranchial duct cyst; thyroid gland
Page 1 of 2
This report contains information that is confidential and is intended for the use ofthe individual or entity named on page I. If
‘you have received this report in error, please notify WADDL immediatelyHISTOPATHOLOGY REPORT 02/05/16 WADDL #2016-960
3. Enteritis, lymphoplasmacytic, chronic, segmental, mild
COMMENTS: There are no significant histologic abnormalities noted in this bear. The focus of nodular
fibroplasia within the diaphragm may reflect an old focal injury‘inflammatory process or possibly an early
neoplastic lesion. The inciting cause is not determined, and it is considered an incidental finding in this
case. Ultimobranchial duct cysts are derived from pharyngeal pouches that fuse incorrectly during
embryonic development. There is some mild, chronic inflammation associated with the cyst. The enteritis,
is mild, and likely had no clinical significance. The changes in the liver are considered normal in a
hibemating animal. Splenic congestion is attributed to terminal sedation and euthanasia.
WORK PENDING: None
Dr. Laura B. Williams/JDRijar/jdb
Phone contact: An email summarizing these results sent to Dr. Clyde on 2/4/16,
Page 2 of 2
This report contains information that is confidential and is intended forthe use of the individual or entity named on page I. If
‘you have received this report in error, please notif WADDL immediately.