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  • Case-Control Study 1: Design and Odds Ratio: Preben Aavitsland

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    This document discusses the design of case-control studies, including their advantages over cohort studies. It notes that case-control studies are well-suited for investigating the causes and protective factors of diseases. They are easier to perform and analyze than cohort studies and can be used to study both outbreaks and endemic diseases, though thorough planning is required. The document also outlines some of the problems with cohort studies, such as the large sample size needed and time and cost involved.

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    Association Study

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    This document discusses the design of case-control studies, including their advantages over cohort studies. It notes that case-control studies are well-suited for investigating the causes and protective factors of diseases. They are easier to perform and analyze than cohort studies and can be used to study both outbreaks and endemic diseases, though thorough planning is required. The document also outlines some of the problems with cohort studies, such as the large sample size needed and time and cost involved.

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    17 views5 pages

    Case-Control Study 1: Design and Odds Ratio: Preben Aavitsland

    Uploaded by

    chhatra
    This document discusses the design of case-control studies, including their advantages over cohort studies. It notes that case-control studies are well-suited for investigating the causes and protective factors of diseases. They are easier to perform and analyze than cohort studies and can be used to study both outbreaks and endemic diseases, though thorough planning is required. The document also outlines some of the problems with cohort studies, such as the large sample size needed and time and cost involved.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
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    of 5

    Case-control study 1:

    Design and odds ratio

    Preben Aavitsland

    (partly based on Epiet 2004)


    Contents
    • Monday 1
    – Design: Case-control study as a smarter cohort study
    – The odds ratio
    • Tuesday 2
    – Choosing cases and controls
    – Matching
    – Power calculation
    • Wednesday
    – Case-control studies in outbreaks
    • Thursday 3
    – Bias and confounding
    – Analysis
    Why case-control study
    • Best way to acquire knowledge about
    causes and protective factors of disease
    • Both for outbreaks and endemic diseases
    • Easy to perform and analyse
    • Needs thorough planning
    • Next step after surveillance and outbreak
    investigations
    The cohort study

    exposed

    unexposed
    Problems of cohort
    • Large sample size required
    – At least if disease is rare
    • Latency period
    • Time consuming
    • Loss to follow up
    • Changing exposure over time
    • Only one exposure
    • Ethical considerations
    • Cost

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