You are on page 1of 2

PATHOPHYSIOLOGY

Precipitating Factors
Predisposing Factors

Type II Diabetes Mellitus

Tissue resistance to insulin

Impaired utilization of insulin & glucose

Inability to glucose to penetrate the cell

Hyperglycemia

Stress kidney filtration mechanism

Blood protein leak in urine

Pressure of blood vessel in urine

Thickening of glomerulus

Filtration of protein

DIABETIC NEPHROPATHY

Proteinuria

CHRONIC KIDNEY DESEASE


reduced kidney function

NA & H20 retention

Stimulates production of
angiotensin

Hypertension

You might also like