Asian College of Science and Technology

College of Nursing
DRUG STUDY

NAME: Rochelle Pesquera BSN AREA: OB WARD

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Ampicillin Na Omnipen Belongs to the class GI disturbances eg Hold medication & promptly report
Hypersensitivity
Polycillin A penicillin that inhibits of penicillins with diarrhea, nausea & rash (although common w/
Principen to penicillin. ampicillin,may, indicate
cell wall synthesis in extended spectrum. vomiting; skin rashes,
Glandular fever of hypersencitivity)or diarrhea
supceptible Used in the pruritus, urticaria,
lymphatic -Evaluate IV site for Phlebitis.
microorganism. systemic treatment Treatment of UTI, otitis erythema multiforme, -Check IM injection site for pain,
of infections. media, sinusitis, leukemia. exfoliative dermatitis, induration.
bronchitis, anaphylactic shock, Monitor I& O, urinalysis, renal
anemia, thrombocytopenia, function test.
uncomplicated communit
eosinophilia, -Asses for signs of superinfection.
y-acquired
agranulocytosis, laryngeal
pneumonia, Haemophilus
stridor, high fever.
influenzae infections,
invasive salmonellosis &
listerial meningitis.

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GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Nalbuphine Nalbuphine A narcotic agonist- Narcotic agonist, Relief of moderate to Respiratory rate less than Abrupt withdrawal after -Reassure px about addiction
Hydrochloride Nubain antagonist that binds antagonist. severe pain. Also as a 12 bpm. Cautions. Hepatic prolonged use may liability: most patients who receive
with opioid receptors in supplement to balanced or renal impairement, produce symtoms of opiates for medical reasons do not
the CNS. May displace anesth for pre- & post-op respiratory depression, narcotic withdrawal, such develop dependency syndromes
opioid agonist & analgesia & for obstet recent biliary tract as abdominal cramping,
competively inhibit analgesia during labor & surgery, head trauma, rhinorrhea, lacrimation,
their action: may delivery. increased intracranial anxiety, fever &
precipitate withdrawal pressure (ICP), pileorection (goose
symptoms. pregnancy, those bumps). Over dose results
suspected to be opioid in severe respiratory
Effect: Alters the dependent. depression, skeletal muscle
perception of and flaccidity, cyanosis &
emotional response to extreme somnolence
pain. progressing to seizures,
stupor & coma.

SIDE EFFECTS/ADVERSE
GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS REACTIONS NURSING RESPONSIBILITY
Dexamitasone Na Desoximetasone or A long-acting Belongs to the class of Active untreated Inhalation: cough, dry -Monitor I & O, daily weight
Asthma & related
Phosphate Dextramethopan, glucocorticoid that glucocorticoids. Used infections, fungal, mouth, hoarseness, throat -Assess for edema
bronchospastic irritation. -Evaluate food tolerate & bowel
inhibits accumulation of in systemic tuberculosis, or viral
disorder unresponsive Long term therapy may activity
inflammatory cells at corticosteroid diseases of the eye.
to other cause muscle -Report hyperacidity promptly
inflammatory sites, preparations. wasting(specially arm & -Check V/S at least BID
phagocytosis & release therapy, allergic
legs), -Monitor Hypercalcemia
of mediators of rhinitis, inflammatory Risk of osteoporosis & -Assess emotional status, ability to
inflammation. nasal condition. Also spontaneous fracture, sleep.
used in cerebral muscle wasting,
nitrogenepletion,hyperglyce
edema due to
mia
malignancy

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GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Furosemide Apo-ferosemide A loop diuretic that Belongs to the class Acute pulmonary Hypersensitivity to Increased Urinary -Observe px receives parenteral
enchances excretion of of high-ceiling edema, CHF, edema of n sulfonamides, severe Na & frequency & urine volume. drug carefully.
sodium, chloride, & sulfonamide diuretics. ephrotic syndrome, vol depletion. Anuria not Nausea, dyspepsia, -Monitor BP during period
severe ofdiuresis & through period of
potassium by direct responsive to a trial dose abdominal cramps,
HTN, ascites& edema du dosage adjustment.
action at the ascending of furosemide diarrhea or constipation,
e to liver cirrhosis, -Monitoe for V/S of hypokalemia
limb of the limb of acute renal failure electrolyte disturbances. -Monitor I & O ratio & patter.
henle. AR: Virgorous diuresis may Report decreased or unusual can
lead to profound water loss result in dehydration &
Effect: procedures & Electrolyte hypovelemia, circulatory collapse,
depletion,resulting & hypotention.
dieresis & lowers BP.
hypokalemia,hyponatrimia
& dehydration.

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Hydralazine HCL Hydralazine An antihypertensive Belongs to the class of Treatment of HTN, in Severe tachycardia, Tachycardia, palpitation, -Monitor for Headache.
Apresoline, with direct vasodilating hydrazinophthalazine conjunction w/ β-blocker dissecting aortic angina pectoris, severe -Palpitations. Tachycardia
Novohylazine effects on arterioles. derivatives. Used in & thiazide diuretic. W/ aneurism, heart failure w/ headache, GI disturbances -Assess for peripheral edema of
the treatment of isosorbide dinitrate in high cardiac output, hands, feet
eg anorexia, nausea,
hypertension the management myocardial insufficiency -Monitor pattern of daily bowel
Therapeutic Effect : vomiting & diarrhea.
of heart failure due to mechanical activity & stool consistency
Decreases BP & obstruction. Idiopathic Flushing, dizziness & nasal
Slow IV Hypertensive SLE. Do not give to congestion. Postural
systemic resistance.
crisis 5-10 mg patients following MI. 1st hypotension, Fever, chills,
repeated over 20 mins. 2 trimesters of pregnancy pruritus, rashes
Continuous IV 200-300
mcg/min. Maintenanc
e 50-150 mcg/min. May
also be given IM.

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Ketorolac Toradol An NSAID that inhibits Belongs to the class of Relief of ocular itching Hypersensitivity to aspirin Headache, nausea, -Patient’s who have asthma, aspirin
tromethamine prostaglandin synthesis acetic acid derivatives due to seasonal allergic or other NSAIDs, asthma. abdominal cramps, or pain induced allergy, & nasal polyps are
and reduces and related conjunctivitis. Hypovolaemia or dyspepsia. at increased risk for developing

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 prostaglandin levels in substances of non- Prophylaxis & reduction dehydration. Do not give Rare reaction with long- hypersensitivity reactions. Assess
the aqueous humor. steroidal of inflammation & postoperatively to term use include peptic for rhinitis, asthma & Urticaria.
antiinflammatory and associated symptoms patients with high risk of ulcer disease. GI bleeding, -Assess pain prior to and 1-2 hr. ff.
Therapeutic Effect: antirheumatic haemorrhage. History of administration.
after ocular surgery gastric, severe hepatitis
products. peptic ulcer or -Ketorolac therapy should always
Relieves pain reactions. (cholestasis,
coagulation disorders given initially by the IM or IV route.
jaundis) -Advice px to consult if rash,
stimulus & reduces
itching, visual, disturbances,
intraocular tinning, weight gain, edema, black
inflammation. stools, persistent headache, or
influenza like syndromes occur.

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Mg Chloride Mg Citrate, An antacid, laxative, Antacid, Treatment of Appendicitis or symptoms Flushing, sweating, -Asses for relief of Gastric distress
electrolyte, and Anticonvulsant, hypomagnesemia of appendicitis, ileostomy, hypotension, muscular -Monitor renal function.
Mg hydroxide anticonvulsant. As an electrolyte, laxative. accompanied by signs intestinal obstruction, weakness, sedation & -Monitor pattern of bowel activity &
of tetany. Control of confusion; decreased deep stool consistency.
antacid acts in the severe renal impairment.
Mg oxide HTN, encephalopathy tendon reflexes; resp -Maintain adequate fluid intake.
stomach to neutralize Belongs to the class of
electrolyte solutions & convulsions. paralysis
gastric acid. Prevention & control of
Mg protein complex used in I.V. solutions.
convulsions in patients
Mg SO4 w/ preeclampsia or
eclampsia. Prevention of
hypomagnesemia in

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GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Metronidazole HCL Flagyl A nitroimidazole Belongs to the class of Treatment of infections Admixture w/ 10% norexia, nausea, -Avoid use unless needed
derivative that disrupts imidazole derivative caused by Bacteriodes Glucose, penicillin G, K, abdominal pain, vomiting, -Administer oral doses w/ food
bacterial & protozoal antibacterials. Used in fragilis. Prevention of Ringer Lactated Soln due vertigo, tiredness & dark -Apply topically after cleansing the
the systemic is contraindicated to coloration of the urine if area.
DNA, INHIBITING ACID post-op infections due to
treatment of chemical incompatibility used to treat Advise px that cosmetics may bew
SYNTHESIS. anaerobic bacteria &
infections. trichomoniasis & used over the area after
treatment of amoebic amoebiasis application.
abscess of the liver & -Reduce dosage in hepatic disease.
acute intestinal
amoebiasis

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Oxytocin Pitocin, Syntocinon Ab oxytocin that effects Uterine smooth Induction & Auquate uterine activity Hypertonicity may occur -Ensure fetal position & site &
uterine myofibril augmentation of labor, that fails to progress, with tearing of the uterus, ansence of complications that are
muscle stimulant. contraindicated w/ oxytoxin before
activity and stimulates to control postpartum cephalopelvic increased bleeding,
bleeding & uterine therapy.
mammary smooth disproportion, fetal abruption placentae. &
Belongs to the class hypotonicity in the 3rd -Establish uterine contractions that
muscle. of oxytocin and distress without imminent cervical, vaginal
stage of labor & to rate similar to normal labor,
analogues. Used in promote lactation in ddelivery. lacerations. monitor rate & strength of
Therapeutic effect: posterior pituitary contraction.
cases of faulty milk
Contracts uterine lobe hormone ejection
smooth muscle. preparations.
Enhances lactation.

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Ranitidine HCL Ranitidine Bismuth An anticular thet Belongs to the class of Peptic disease eg stress History of acute porpyrria, Reversible hepatitis and -Administer oral drug w/ meals &
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 citrate inhibits histamine H2-receptor ulceration, gastroesopha Cautions: Renal/hepatic blood dyscrasias occur at bedtime
action at histamine 2 antagonists. Used in geal reflux disease, impairment elderly. rarely. -Decrease does in renal & liver
Zantac receptors pf gastric the treatment of selected cases of failure
peptic ulcer and persistent dyspepsia, -Provide concurrent antacid
parietal cells.
gastro-oesophageal pathological therapy to relieve pain.
reflux disease (GERD). hypersecretory states -Administer IM dose undiluted deep
Therapeutic effect: eg Zollinger-Ellison into large muscle group
Inhibits gastric acid syndrome & potential -Arrange for regular follow ur,
acid aspiration during including blood test, to evaluate
secretion when effects.
general anesthesia or
fasting, at night, or childbirth
when stimulated by
food. Caffeine, or
insulin.

GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Tranixamic Acid Lystedia Tranexamic acid ; Treatment & prophylaxis Severe renal failure, GI disturbances, Evaluate for use warnings prior to
Cyklokapron Antifibrinolytic agent Belongs to the class of of hemorrhage associate hypotension, thrombotic beginning therapy. See
active intravascular Administration for infusion
that competitively amino acid d w/ excessive complication, transient
fibrinolysis. clotting, disturbance of color vision specifics. Evaluate therapeutic
inhibits breakdown of antifibrinolytics. Used
effectiveness and adverse effects
fibrin clots. It blocks in the treatment of thromboembolic
on a regular basis. Ophthalmic
binding of plasminogen hemorrhage. disease, colour vision examination is recommended at
and plasmin to fibrin, disorder, subarachnoid baseline and regular intervals if
thereby preventing used longer than several days.
bleeding Teach patient possible side
haemostatic plug
effects/appropriate interventions
dissolution
and adverse symptoms to report

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GENERIC NAME BRAND NAME ACTION CLASSIFICATION INDICATION CONTRAINDICATIONS SIDE EFFECTS/ADVERSE NURSING RESPONSIBILITY
REACTIONS
Paracetamol Acetaminophen Paracetamol produces Non steroidal For pain or pyrexia Hypensensitivity, Drowsiness, fatigue, Do not exceed the recommended
Algina analgesia by raising Anti inflammatory Fever analgesic nephropathy children may occasionally dosage.
Algitab the threshold of the Opioid analgesics. Post operative pain renal and hepatic experience low blood sugar
Aminol pain center in the Avoid using multiple preparations
and tremor or feel hungry,
Atamol brain and by containing acetaminophen.
faint or confused rashes or
Bepamol obstructing impulses
itching Carefully check all OTC products.
Calpol at the pain-mediating
Cemolinga chemoreceptors. The
Allergic type reaction hives, Give drug with food if GI upset
cetacin drug produces
wheezy breathing, swelling occurs.
antipyresis by an
action on the of the face, lips, tongue or
hypothalamus; heat Discontinue drug if hypersensitivity
around the eyes blood
dissipation is increased reactions occur.
stained urine output
as a result of abnormal bruising or
vasodilation &
bleeding jaundice
increased peripheral
blood flow