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  • PF2001 Mefenamic Acid

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    AlvitaWidyastuti
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    PF2001 Mefenamic acid

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    96 views1 page

    PF2001 Mefenamic Acid

    Uploaded by

    AlvitaWidyastuti

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Mefenamic acid

    COOH
    H
    N

    2-[(2,3-dimethylphenyl)amino]benzoic acid
    N-(2,3-xylyl)anthranilic acid

    INN derived from methyl + fen (from phenyl) + am (from amino) + ic


    (from benzoic).

    • Ponstan® - Cemidex
    o Tablets, capsules
    • Ponmel® - Clonmel
    o Tablets, capsules
    • Mefac® - Rowex
    o Tablets, capsules

    Mefenamic acid synthesis

    COOH COOK
    H
    Cl NH2 N
    K2CO3
    +

    o-chlorobenzoic acid 2,3-dimethylaniline

    HCl
    J. Med. Chem., 1968, 11, 111
    COOH
    H
    N mefenamic acid
    m.p. 229oC

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