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  • Epirizine

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    EPIRIZINE TAB is a tablet containing 10 mg of cetrizine, an antihistamine H-1 receptor antagonist used for treating allergic conditions like rhinitis, conjunctivitis, and urticaria. It works by blocking histamine receptors and stabilizing mast cells. EPIRIZINE is rapidly absorbed, highly protein bound, and has an 11 hour half-life. It is primarily excreted unchanged in urine and does not significantly cross the blood-brain barrier. Common side effects include mild sedation and occasional gastrointestinal issues like nausea. Safety during pregnancy has not been established.

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    EPIRIZINE TAB is a tablet containing 10 mg of cetrizine, an antihistamine H-1 receptor antagonist used for treating allergic conditions like rhinitis, conjunctivitis, and urticaria. It works by blocking histamine receptors and stabilizing mast cells. EPIRIZINE is rapidly absorbed, highly protein bound, and has an 11 hour half-life. It is primarily excreted unchanged in urine and does not significantly cross the blood-brain barrier. Common side effects include mild sedation and occasional gastrointestinal issues like nausea. Safety during pregnancy has not been established.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
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    16 views1 page

    Epirizine

    Uploaded by

    mahgad
    EPIRIZINE TAB is a tablet containing 10 mg of cetrizine, an antihistamine H-1 receptor antagonist used for treating allergic conditions like rhinitis, conjunctivitis, and urticaria. It works by blocking histamine receptors and stabilizing mast cells. EPIRIZINE is rapidly absorbed, highly protein bound, and has an 11 hour half-life. It is primarily excreted unchanged in urine and does not significantly cross the blood-brain barrier. Common side effects include mild sedation and occasional gastrointestinal issues like nausea. Safety during pregnancy has not been established.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
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    of 1

    http://www.eipico.com.eg/PRODUCT.ASP?

    id1=6&id2=0 &id4=4

    EPIRIZINE TAB.

    Composition
    Each tablet contains:
    Cetrizine 10 mg

    Properties and Mode of Action


    EPIRIZINE is an antihistaminic H-1 receptor antagonist with some mast cell stabilizing activity.It is a long-acting
    antihistaminic with low central sedative activity.
    EPIRIZINE has also antiemetic properties.
    EPIRIZINE is rapidly absorbed from the gastrointestinal tract after oral administration, peak plasma concentrations being
    attained in about 1 hour. It is highly bound to plasma proteins and has a plasma half-life of about 11 hours. It is excreted
    primarily in the urine mainly as unchanged drug and does not appear to cross the blood-barrier to a significant extent.
    Traces of the drug have been detected in breast milk.

    Indications
    For the symptomatic relief of hypersensitivity reactions including rhinitis, allergic conjunctivitis, acute and chronic urticaria
    and other allergic dermatologic disorders.

    Dosage and Administration


    Adults and Children 12 years and Older:
    One tablet once daily.

    Precautions
    In patients with renal impairment, it is recommended that the dosage be reduced to half the usual daily dose.
    If the patient taking EPIRIZINE feels sedation, he must be advised not to drive vehicles or to operate machinery.
    Safety during pregnancy has not been established yet, therefore EPIRIZINE should be used only if potential benefit
    justifies potential risk.
    As the active ingredient of EPIRIZINE is excreted in breast milk, it is not indicated in lactating women.

    Side effects
    EPIRIZINE is generally well-tolerated, little antimuscarinic side effects, mild sedation and occasional gastrointestinal side
    effects as nausea and vomiting may occur.

    Presentation
    Box of 1 strip of 10 tablets.

    1 of 1 3/2/2011 7:26 PM

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