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Pathophysiology of Stab wound

Risk factors:

knife, samurai, blade, something sharp

Disruption of Cell Membrane

entrance of pyrogens

Start of Inflammatory Process

Hypothalamus (prostaglandin production)

Mast Cells

Fever (value)

Bradykinin

Prostaglandin

Histamine

Leukotrienes

interleukin - 1

Vasoconstriction Vasodilation Prevent spill of blood Increase permeability increase WBC = (value)

Diapedesis or Accumulation of WBC to the interstitial compartment

Phagocytosis

Swelling

Exudates

ruptured of the affected part

sepsis

Pain If treated if NOT treated

RECOVERY

Septic shock: Decrease Blood Pressure Decreased Blood Volume

DEATH

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