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Hygienic Standard for Cosmetics

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2

21 3
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3 INCI 59
4 INCI 70
5 INCI 75
6 77
7 INCI 90

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I

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pH
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239
241
- 243
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252

D2 D3254
II

256
258
UVA

260
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SPF 283
287
PFA 289

III

General Principle

, 76768EEC 2005 11 21 (The Cosmetics

Directive of the Council European Communities, 76768EEC, and amendments until 21


November 2005)

4.1

4.2

4.2.1

2(1)

4.2.2

2(2)

4.2.3

3 , ,

4.2.4

4 , ,

4.2.5

5 , ,

4.2.6

6 , ,

4.2.7

7 , ,

4.3

4.2
, ,

4.3.1
4.3.1.1

500CFUmL 500CFUg
4.3.1.2

1000CFUmL 1000CFUg

4.3.1.3

4.3.1.4

100CFUmL 100CFUg

4.3.2

1
1

mg/kg

40

10

2000

2(1) (1)(2)
()

, , -

, , -Trichlorotoluene (CAS No 98-07-7)

, -

, -Dichlorotoluene (CAS No 98-87-3)

-Chlorotoluene (CAS No100-44-7)

1-(1-)

1-(1-Naphthylmethyl) quinolinium (CAS No 65322-65-8)

1-(4-)-4,4--3-(1,2,4--1-)-3-

1-(4-Chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol(CAS No 107534-96-3)

1-(4-)-1--3-

1-(4-Methoxyphenyl)-1-penten-3-one (CAS No 104-27-8)

1,1,2-

1,1,2-Trichloroethane (CAS No 79-00-5)

1,1,3,3,5--4,6-()

1,1,3,3,5-Pentamethyl-4,6-dinitroindane (moskene)

[(1,1-)-4,4-]

[(1,1-Biphenyl)-4,4-diyl]diammonium sulphate (CAS No 531-86-2)

10

[1,1-()](, )

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts

11

1,2,3,4,5,6-,

1,2,3,4,5,6-Hexachlorcyclohexanes with the exception of those specified elsewhere in this Annex

12

1,2,3-

1,2,3-Trichloropropane (CAS No 96-18-4)

13

1,2,4-

1,2,4-Triazole (CAS No 288-88-0)

14

1,2- C7-11

1,2-Benzenedicarboxylic acid di-C7-11, branched and linear alkylesters (CAS No 68515-42-4)

15

1,2-

1,2-Benzenedicarboxylic acid, dipentylester, branched and linear(CAS No 84777-06-0)


n-Pentyl-isopentylphthalate
Di-n-pentyl phthalate (CAS No 131-18-0)
Diisopentylphthalate (CAS No 605-50-5)

16

1,2-(2-)

1,2-Bis(2-methoxyethoxy)ethane triethylene glycol dimethyl ether (CAS No 112-49-2)

17

1,2--3-

1,2-Dibromo-3-chloropropane (CAS No 96-12-8)

18

1,2-

1,2-Dibromoethane (CAS No 106-93-4)

19

1,2--3-

1,2-Epoxy-3-phenoxypropane (CAS No 122-60-1)

20

1,2-

1,2-Epoxybutane

21

1,3,5-()-1,3,5--2,4,6(1H,3H,5H)

1,3,5-Tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (CAS No 2451-62-9)

22

1,3,5--[(2S 2R)-2,3-]-1,3,5 -2,4,6-(1H,3H,5H)-

1,3,5-Tris-[(2S and 2R)-2,3-Epoxypropyl]-1,3,5-triazine-2,4,6-(1H,3H,5H)-trione (CAS No 59653-74-6)

23

1,3-()-

1,3-Bis(vinylsulfonylacetamido)-propane (CAS No 93629-90-4)

24

1,3--2-

1,3-Dichloropropan-2-ol (CAS No 96-23-1)

25

1,3-

1,3-Dimethylpentylamine and its salts

26

1,3-

1,3-Diphenylguanidine (CAS No 102-06-7)

27

1,3-

1,3-Propanesultone (CAS No 1120-71-4)

28

1,4,5,8-( 1)

1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1) (CAS No 2475-45-8)

29

1,4-(-)

1,4-Dichlorobenzene(p-dichlorobenzene) (CAS No 106-46-7)

30

1,4--2-

1,4-Dichlorobut-2-ene (CAS No 764-41-0)

31

11--()-4--3,20-,

11-Alpha-hydroxypregn-4-ene-3,20-dione and its esters

32

1- 2-

1-and 2-Naphthylamines and their salts

33

1--3,4,5-

1-Bromo-3,4,5-trifluorobenzene (CAS No 138526-69-9)

34

1-()

1-Bromopropane(n-propyl bromide) (CAS No 106-94-5)

35

1--3-(N-)

1-Butyl-3-(N-crotonoylsulphanilyl)urea

36

1--2,3-

1-Chloro-2,3-epoxypropane (CAS No 106-89-8)

37

1--4-

1-Chloro-4-nitrobenzene (CAS No 100-00-5)

38

1--1-()

1-Dimethylaminomethyl-1-methylpropyl benzoate (amylocaine) and its salts

39

1--1-

1-Ethyl-1-methylmorpholinium bromide (CAS No 65756-41-4)

40

1--1-()

1-Ethyl-1-methylpyrrolidinium bromide (CAS No 69227-51-6)

41

1--2,4-(2,4--CI76050)

1-Methoxy-2,4-diaminobenzene (2,4-diaminoanisole-CI 76050) and their salts

42

1--2,5-(2,5-)

1-Methoxy-2,5-diaminobenzene (2,5-diaminoanisole) and their salts

43

1--3--1-

1-Methyl-3-nitro-1-nitrosoguanidine (CAS No 70-25-7)

44

( 3 )

(1R,2S)-Hexahydro-1,2-dimethyl-3,6-epoxyphthalic anhydride (cantharidin), with the exception of


cantharides tincture listed in table 3

45

(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethano- naphthalene
(isodrin-ISO)

46

(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethano-napht
halene (endrin-ISO)

47

1--2-

1-Vinyl-2-pyrrolidone (CAS No 88-12-0)

48

2-(2-(4-Chlorophenyl)-2-phenylacetyl) indan 1,3-dione (chlorophacinone-ISO)

49

(+/-)-2-(2,4-)-3-(1H-1,2,4--1-)-1,1,2,2-

(+/-)-2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl-1,1,2,2-tetrafluoroethylether (CAS No
112281-77-3)

50

2-(2-)

2-(2-Methoxyethoxy)ethanol (CAS No 111-77-3)


51

2-(4--2-)-N,N-

2-(4-Allyl-2-methoxyphenoxy)-N,N-diethylacetamide and its salts

52

2-(4--)

2-(4-tert-Butylphenyl)ethanol (CAS No 5406-86-0)

53

2,2,2-

2,2,2-Tribromoethanol (tribromoethyl alcohol)

54

2,2,2--1,1-

2,2,2-Trichloroethane-1,1-diol

55

2,2,6--4-()

2,2,6-Trimethyl-4-piperidyl benzoate (benzamine) and its salts

56

2,2-()

2,2-(Nitrosoimino)bisethanol (CAS No 1116-54-7)

57

2,2-

2,2-Bioxirane (CAS No 1464-53-5)

58

2,2--3,3',5,5',6,6'-()

2,2-Dihydroxy-3,3,5,5,6,6-hexachlorodiphenylmethane (hexachlorophene)

59

2,2--2-

2,2-Dibromo-2-nitroethanol (CAS No 69094-18-4)

60

2,3,4--1-

2,3,4-Trichlorobut-1-ene (CAS No 2431-50-7)

61

2,3,7,8---

2,3,7,8-Tetrachlorodibenzo-p-dioxin

62

2,3--1-

2,3-Dibromopropan-1-ol (CAS No 96-13-9)

63

2,3--2-

2,3-Dichloro-2-methylbutane

64

2,3-

2,3-Dichloropropene (CAS No 78-88-6)

65

2,3-

2,3-Dinitrotoluene (CAS No 602-01-7)

66

2,3--1-

2,3-Epoxypropan-1-ol (CAS No 556-52-5)

67

2,3-.-

2,3-Epoxypropyl o-tolyl ether (CAS No 2210-79-9)

68

2,4,5-
2,4,5-

2,4,5-Trimethylaniline (CAS No 137-17-7)


2,4,5-Trimethylaniline hydrochloride (CAS No 21436-97-5)

69

2,4,6-

2,4,6-Trichlorophenol (CAS No 88-06-2)

70

2,4-

2,4-Diaminophenylethanol and its salts

71

2,4--3-

2,4-Dihydroxy-3-methylbenzaldehyde (CAS No 6248-20-0)

72

2,5-

2,5-Dinitrotoluene (CAS No 619-15-8)

73

2,6--4-

2,6-Dibromo-4-cyanophenyl octanoate (CAS No 1689-99-2)

74

(2,6--1,3--4-)

2,6-Dimethyl-1,3-dioxan-4-yl acetate (dimethoxane)

75

2,6-

2,6-Dinitrotoluene (CAS No 606-20-2)

76

2-[2-Hydroxy-3-(2-chlorophenyl)carbamoyl-1-naphthylazo]-7-[2-hydroxy-3- (3-methylphenyl)
2-[2--3-(2-)-1-]-7-[2--3-(3-
)-2-[2--3-(3-)--1-]-7-[2--3-(3- -2-[2-hydroxy-3-(3-methylphenyl)-carbamoyl-1-naphthylazo]-7-[2-hydroxy-3-(3-methylphenyl)
-carbamoyl-1-naphthylazo]fluoren-9-one(EC No 420-580-2)
)--1-]-9-

77

2-(4--N-(2-))

2-[4-Methoxybenzyl-N-(2-pyridyl) amino] ethyldimethylamine maleate

78

2-{4-(2- )-6-[4--3-(5--2--4-
)-2--7-]-1,3,5-}-2-

2-{4-(2-Ammonio propylamino)-6-[4-hydroxy-3-(5-methyl-2-methoxy-4-sulfamoylphenylazo)-2
-sulfonatonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-2-aminopropyl formate(EC No 424-260-3)

79

2-Acetoxyethyltrimethylammonium hydroxide (acetylcholine )and its salts

80

2--(N,N,N',N-)

2-Alpha-cyclohexylbenzyl (N,N,N',N-tetraethyl) trimethylenediamine (phenetamine)

81

2--1,2-(4-)

2-Amino-1,2-bis(4-methoxyphenyl)ethanol and its salts

82

2--4-

2-Amino-4-nitrophenol

83

2--5-

2-Amino-5-nitrophenol

84

2-

2-Bromopropane (CAS No 75-26-3)

85

2-

2-Butanone oxime (CAS No 96-29-7)

86

2--6--4-()

2-Chloro-6-methylpyrimidin-4-yldimethylamine (crimidine-ISO)

87

3--4--2-

2-Diethylaminoethyl 3-hydroxy-4-phenylbenzoate and its salts

88

2-

2-Ethoxyethanol (CAS No110-80-5)

89

2-

2-Ethoxyethyl acetate (CAS No 111-15-9)

90

2-

2-Ethylhexanoic acid (CAS No 149-57-5)

91

2-[[[3,5-(1,1-)-4-]-]-]

2-Ethylhexyl[[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-methyl]thio]acetate (CAS No 80387-97-9)

92

(2--4-)

(2-Isopropylpent-4-enoyl) urea (apronalide)

93

2-

2-Methoxyethanol (CAS No109-86-4)

94

2-

2-Methoxyethyl acetate (CAS No 110-49-6)

95

2-

2-Methoxypronyl aceate (CAS No 70657-70-4)

96

2-

2-Methoxypropanol (CAS No 1589-47-5)

97

2-

2-Methylaziridine (CAS No 75-55-8)

98

2-

2-Methylheptylamine and its salts

99

2---

2-Methyl-m-phenylene diisocyanate (CAS No 91-08-7)

100

2--

2-Methyl-m-phenylenediamine

101

2-

2-Naphthol

102

2-

2-Nitroanisole (CAS No 91-23-6)

103

2-

2-Nitronaphthalene (CAS No 581-89-5)

104

2-

2-Nitropropane (CAS No 79-46-9)

105

2-

2-Nitrotoluene (CAS No 88-72-2)

106

2-

2-Pentylidenecyclohexanone (CAS No 25677-40-1)

107

2--1,3-()

2-Phenylindan-1,3-dione (phenindione)

108

(2RS,3RS)-3-(2-)-2-(4-)-[(1H-1,2,4--1-)] (2RS,3RS)-3(2-Chlorophenyl)-2-(4-fluorophenyl)-[1H-1,2,4-triazol-1-yl]methyl]oxirane (CAS No


133855-98-8)

109

3-(1-)-4-

3-(1-Naphthyl)-4-hydroxycoumarin

110

3-(4-)-1,1-; -TCA

3-(4-Chlorophenyl)-1,1-dimethyluronium trichloroacetate;monuron-TCA (CAS No 140-41-0)

111

3-(4-)-1,1-

3-(4-Isopropylphenyl)-1,1-dimethylurea (CAS No 34123-59-6)

112

3,3-

3,3-Dichlorobenzidine (CAS No 91-94-1)

113

3,3-

3,3-Dichlorobenzidine dihydrochloride (CAS No 612-83-9)

114

3,3-

3,3-Dichlorobenzidine dihydrogen bis(sulphate) (CAS No 64969-34-2)

115

3,3-

3,3-Dichlorobenzidine sulphate (CAS No 74332-73-3)

116

3,3-

3,3-Dimethoxybenzidine (CAS No119-90-4)

117

[3,3-[1,1-]-4,4-]

3,3-Dimethyl [1,1-biphenyl]-4,4-diyl]diammonium bis(hydrogen sulphate) (CAS No 64969-36-4)

118

3,3-(4-)2-[C]()

3,3-Bis (4-hydroxyphenyl) phthalide (phenolphthalein)

119

3,4,5-

3,4,5-Trimethoxyphenethylamine and its salts

120

3,4,5-()

3,4,5-Tribromosalicylanilide (tribromsalan)

121

3,4--2--2--4--2H,5H (3,2-c)-(1)-5- 3,4-Dihydro-2-methoxy-2-methyl-4-phenyl-2H,5H,pyrano [3,2-c]-[1]benzopyran-5-one (cyclocoumarol)


()

122

3,4-

3,4-Dinitrotoluene (CAS No 610-39-9)

123

3,5,5--2-

3,5,5-Trimethylcyclohex-2-enone (CAS No 78-59-1)

124

3,5--4-

3,5-Dibromo-4-hydroxybenzonitrile (CAS No 1689-84-5)

125

3,5-

3,5-Dinitrotoluene (CAS No 618-85-9)

126

3,6,10--3,5,9--2-

3,6,10-Trimethyl-3,5,9-undecatrien-2-one (CAS No 1117-41-5)

127

3,7-(6,7-)

3,7-Dimethyl-2-octen-1-ol (6,7-Dihydrogeraniol) (CAS No 40607-48-5)

128

3--5,6,7,8--5,5,8,8--2-( 3-Ethyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-acetonaphthone (acetyl ethyl tetra methyl


tetralin, AETT) or 7- acetyl-6-ethyl-1,1,4,4-tetramethyl-1,2,3,4- tetrahydronaphtalen
,AETT) 7--6--1,1,4,4--1,2,3,4-

129

(3-)-(4--3-)-2-

(3-Chlorophenyl)-(4-methoxy-3-nitrophenyl)methanone (CAS No 66938-41-8)


130

-3-

3-Diethylaminopropyl cinnamate

131

3--2--2-(3-)-1,3-

3-Ethyl-2-methyl-2-(3-methylbutyl)-1,3-oxazolidine (CAS No 143860-04-2)

132

3--4-()

3-Iimidazol-4-ylacrylic acid and its ethyl ester (urocanic acid)

133

(4-(4--3-)-3,5-)

[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl] acetic acid and its salts

134

4-(4-)-2--2-

4-(4-Methoxyphenyl)-3-butene-2-one (CAS No 943-88-4)

135

4,4-(4--2,5-)

4,4-(4-Iminocyclohexa-2,5-dienylidenemethylene) dianiline hydrochloride (CAS No 569-61-9)

136

4,4-

4,4-Bi-o-toluidine (CAS No 119-93-7)

137

4,4---

4,4-Bi-o-toluidine dihydrochloride (CAS No 612-82-8)

138

4,4---

4,4-Bi-o-toluidine sulphate (CAS No74753-18-7)

139

4,4-()

4,4-Bis(dimethylamino)benzophenone (Michlers ketone) (CAS No 90-94-8)

140

4,4-(N,N-)

4,4-Carbonimidoyl bis(N,N-dimethylaniline) (CAS No 492-80-8)

141

4,4--3,3-(3-)

4,4-Dihydroxy-3,3-(3-methylthiopropylidene) dicoumarin

142

4,4-

4,4-Isobutylethylidenediphenol (CAS No 6807-17-6)

143

4,4-(2-)

4,4-Methylene bis (2-ethylaniline) (CAS No 19900-65-3)

144

4,4-

4,4-Methylenedianiline (CAS No 101-77-9)

145

4,4----

4,4-Methylenedi-o-toluidine (CAS No 838-88-0)

146

4,4-()

4,4-Oxydianiline (p-aminophenyl ether) and its salts (CAS No 101-80-4)

147

4,4-

4,4-Thiodianiline and its salts (CAS No 139-65-1)

148

4,6--8-

4,6-Dimethyl-8-tert-butylcoumarin (CAS No 17874-34-9)

149

[4-[[4-()][4-[(3-)]]]-2,5- [4-[[4-(Dimethylamino)phenyl][4-ethyl(3-sulphonatobenzyl)amino]phenyl]methylene]cyclohexa-2,5-die
n-1-ylidene](ethyl)(3-sulphonatobenzyl)ammonium, sodium salt (CAS No 1694-09-3)
-1-]()(3-)

150

4-[4-(1,3--2-)]-1,8--5-

4-[4-(1,3-Dihydroxyprop-2-yl)phenylamino]-1,8-dihydroxy-5-nitroanthraquinone (CAS No
114565-66-1)

151

4--2-

4-Ethoxy-2-benzimidazoleanilide (CAS No 115-96-8)

152

4--2-

4-Amino-2-nitrophenol

153

4-

4-Aminoazobenzene (CAS No 60-09-3)

154

4-

4-Aminosalicylic acid and its salts

155

4- 4-

4-Benzyloxyphenol and 4-ethoxyphenol

156

4--2,6-

4-Cyano-2,6-diiodophenyl octanoate (CAS No 3861-47-0)

157

4---

4-Ethoxy-m-phenylenediamine and its salts

158

(4-)-N-

4-Hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride (CAS No 81881-96-8)

159

4---

4-Methyl-m-phenylene diisocyanate (CAS No 584-84-9)

160

4---

4-Methyl-m-phenylenediamine and its salts

161

4-

4-Nitrobiphenyl (CAS No 92-93-3)

162

4-

4-Nitrosophenol (CAS No 104-91-6)

163

4----

4-o-Tolylazo-o-toluidine(CAS No 97-56-3)

164

4-Phenylazophenylene-1, 3-diamine citrate hydrochloride (chrysoidine citrate hydrochloride)

165

4--3--2-

4-Phenylbut-3-en-2-one

166

4--3--2,6-()

4-tert-Butyl-3-methoxy-2,6-dinitrotoluene (musk ambrette)

167

4-

4-tert-Butylphenol

168

4-

4-tert-Butylpyrocatechol

169

5-(,-)-5-

5-(,-Dibromophenethyl)-5-methylhydantoin

170

5-(2,4--1,2,3,4-)-3--2-

5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluro-2-hydroxymethylterahydrofuran (CAS No
41107-56-6)

171

5-(3--2,4,6-)-2-[1-()]-3--2- 5-(3-Butyryl-2,4,6-trimethylphenyl)-2-[1-(ethoxyimino)propyl]-3-hydroxycyclohex-2-en-1-one (CAS


No 138164-12-2)
-1-

172

5,5'--2,2'--4,4'-

5,5'-Di-isopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite

173

5,5--4-

5,5-Diphenyl-4-imidazolidone

174

5,6,12,13-(2,1,9-d,e,f,:6,5,10-d,e,f)-1,3,8,10(2H,9H) 5,6,12,13-Tetrachloroanthra(2,1,9-def:6,5,10-def)diisoquinoline-1,3,8,10(2H,9H)-tetrone (CAS No


115662-06)

175

5--1,3--2H--2-

5-Chloro-1,3-dihydro-2H-indol-2-one (CAS No 17630-75-0)

176

5--3--1,2,4-

5-Ethoxy-3-trichloromethyl-1,2,4-thiadiazole (CAS No 2593-15-9)

177

5--2,3-

5-Methyl-2,3-hexanedione (CAS No 13706-86-0)

178

5-

5-Nitroacenaphthene (CAS No 602-87-9)

179

5--o-
5--o-

5-Nitro-o-toluidine (CAS No 99-55-8)


5-Nitro-o-toluidine hydrochloride (CAS No 51085-52-0)

180

5--1,2,3--4,6-()

5-tert-Butyl-1, 2, 3-trimethyl-4, 6 dinitrobenzene (musk tibetene)

181

6-(2-)-6-(2-)-2, 5, 7, 10--6-

6-(2-Chloroethyl)-6-(2-methoxyethoxy)-2,5,7,10-tetraoxa-6-silaundecane (CAS No 37894-46-5)

182

(6-(4--3-(2-)-2--7-)-1,3,5--2,4- 6-(4-Hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazine-2,4-diyl)bis[(amino
-1-methylethyl)ammonium]formate (CAS No 108225-03-2)
)[(-1-)]

183

6-()-2,4--3-()

6-(Piperidinyl)-2,4-pyrimidinediamine-3-oxide (minoxidil) and its salts and derivatives

184

6,10--3,5,9--2-

6,10-Dimethyl-3,5,9-undecatrien-2-one (CAS No 141-10-6)

185

6--1-(3-)-4--2--5-[4-()]-1,2- 6-Hydroxy-1-(3-isopropoxypropyl)-4-methyl-2-oxo-5-[4-(phenylazo)phenylazo]-1,2-dihydro-3-pyridine
carbo-nitrile (CAS No 85136-74-9)
-3-

186

6--2-

6-Isopropyl-2-decahydronaphthalenol (CAS No 34131-99-2)

187

2--5-

6-Methoxy-m-toluidine(p-cresidine) (CAS No 120-71-8)

188

7,11--4,6,10--3-

7,11-Dimethyl-4,6,10-dodecatrien-3-one (CAS No 26651-96-7)

189

7-[2--3-(2--N-)]

7-[2-Hydroxy-3-(2-hydroxyethyl-N-methylamino) propyl ] theophylline (xanthinol)

190

7--4-

7-Ethoxy-4-methylcoumarin(CAS No 87-05-8)

191

7-

7-Methoxycoumarin (CAS No 531-59-9)

192

7-

7-Methylcoumarin (CAS No 2445-83-2)

193

9-

9-Vinylcarbazole (CAS No 1484-13-5)

194

A 2:1 mixture of: 4-(7-hydroxy-2,4,4-trimethyl-2-chromanyl)resorcinol-4-yl-tris(6-diazo4-(7--2,4,4--2-)-4--(6-


-5,6--5--1-) 4-(7--2,4,4--2- 5,6-dihydro-5-oxonaphthalen-1-sulfonate) and 4-(7-hydroxy-2,4,4-trimethyl-2-chromanyl)
)(6--5,6--5--1-) 2:1 resorcinolbis(6-diazo-5,6-dihydro-5-oxonaphthalen-1-sulfonate) (CAS No 140698-96-0)

195

1,3,5-(3-)-1,3,5-(1H,3H,5H)--2,4,6- 3,5-(3)-1-[3,5-(3-)-2,4,6--1,3,5-(1H,3H,
5H)--1-]-1,3,5-(1H,3H,5H)--2,4,6-

196

4-[[-(4-)]]-4H-1,2,4- 1-[[-(4-) A mixture of: 4-[[bis-(4-fluorophenyl)methylsilyl]methyl]-4H-1,2,4-triazole and


1-[[bis-(4-fluorophenyl)methyl-silyl]methyl]-1H-1,2,4-triazole(EC No 403-250-2)
]]-1H-1,2,4-

197

: 4--2,6-(2,3-),4-
-6-(3-(6-(3-(4--2,6-(2,3-)-)2-)-4-
-2-(2,3-)--2-)-4--2-(2,3-)-
-2--2-(2,3-),4--6-(3-(4--2,6-(2,3)- -2-)-2-(2,3-)) 4-
-6-(3-(6-(3-(4--2,6-(2,3-)-)-2-)-4-
-2-(2,3-))2-)-2-(2,3-)

198

A mixture of: 5-[(4-[(7-amino-1-hydroxy-3-sulfo-2-naphthyl) azo]-2,5-diethoxyphenyl)azo]-2


5-[(4-[(7--1--3--2-)]-2,5-)]2-[(3-)] 5-[(4-[(7--1--3--2-) -[(3-phosphonophenyl)azo]benzoic acid and 5-[(4-[(7-amino-1-hydroxy-3-sulfo-2-naphthyl)azo]2,5-diethoxyphenyl)azo]-3-[(3-phosphonophenyl) azo]benzoic acid (CAS No 163879-69-4)
]-2,5-)]-3-[(3-)]

A mixture of: 1,3,5-tris(3-aminomethylphenyl)-1,3,5-(1H,3H,5H)-triazine-2,4,6-trione and a mixture of


oligomers of 3,5-bis(3-aminomethylphenyl)-1-poly[3,5-bis(3-aminomethylphenyl)
-2,4,6-trioxo-1,3,5-(1H,3H,5H)-triazin-1-yl]-1,3,5-(1H,3H,5H)-triazine-2,4,6-trione(EC No 421-550-1)

A mixture of: 4-allyl-2,6-bis (2,3-epoxypropyl)phenol,


4-allyl-6-(3-(6-(3-(4-allyl-2,6-bis(2,3-epoxypropyl)-phenoxy)2-hydroxypropyl)-4-allyl-2-(2,3-epoxypro
pyl)phenoxy)-2-hydroxypropyl)-4-allyl-2-(2,3-epoxypropyl)-phenoxy-2-hydroxypropyl-2-(2,3-epoxypro
pyl)phenol,4-allyl-6-(3-(4-allyl-2,6-bis(2,3-epoxypropyl)phenoxy)-2-hydroxypropyl)-2-(2,3-epoxypropy
l)phenoxy)phenol and
4-allyl-6-(3-(6-(3-(4-allyl-2,6-bis(2,3-epoxypropyl)-phenoxy)-2-hydroxypropyl)-4-allyl-2-(2,3-epoxypro
pyl)phenoxy)2-hydroxypropyl)-2-(2,3-epoxypropyl)phenol(EC No 417-470-1)

10

199

4-(3--4-(5-(3--5--1-(4-)-4-)
-2,4-)-4,5--5--1-) 4-(3-
-4-(5-(3--5--1-(4-)-4-)-2,4-
)-4,5--5--1-)

A mixture of: disodium 4-(3-ethoxycarbonyl-4-(5-(3-ethoxycarbonyl-5-hydroxy-1-(4sulfonatophenyl)pyrazol-4-yl)penta-2,4-dienylidene)-4,5-dihydro-5-oxopyrazol-1-yl)


benzenesulfonate and trisodium 4-(3-ethoxycarbonyl-4-(5-(3-ethoxycarbonyl-5-oxido-1(4-sulfonatophenyl)pyrazol-4-yl)penta-2,4-dienylidene)-4,5-dihydro-5-oxopyrazol-1-yl)
benzenesulfonate (EC No 402-660-9)

200

N-[3--2-(2-)]-2-
N-2,3--(2-))-2-
2--N-(2- )-
N-(2,3-)-2-(EC No 412-790-8)

A mixture of: N-[3-Hydroxy-2-(2-Methylacryloylaminomethoxy)propoxymethyl]-2-methylacrylamide


and N-2,3-bis-(2-Methylacryloylaminomethoxy)propoxymethyl]-2-methylacrylamide and
methacrylamide and 2-methyl-N-(2-methylacryloylaminomethoxymethyl)-acrylamide and
N-(2,3-dihydroxypropoxymethyl)-2-methylacrylamide(EC No 412-790-8)

201

4,4-[2-(4-)-3,6-] 6--5,6--5- A mixture of: reaction product of 4,4-methylenebis[2-(4-hydroxybenzyl)-3,6-dimethylphenol] and 6- 1:2 4,4-[2-(4-)-3,6- diazo-5,6-dihydro-5-oxo-naphthalenesulfonate(1:2) and reaction product of 4,4-methylenebis [2-(4] 6--5,6--5- 1:3 hydroxybenzyl)-3,6-dimethylphenol] and 6-diazo-5,6-dihydro-5-oxonaphthalenesulfonate(1:3)(EC No
417-980-4)

202

[a]0.005%(w/w), Absorption oils, bicyclo arom and heterocylic hydrocarbon fraction (CAS No 101316-45-4), if they
contain> 0.005% (w/w) benzo[a]pyrene

203

Acenocoumarol [3-(2-acetyl-1-(p-nitrophenyl) ethyl)-4-hydroxycoumarin]

204

Acetamide (CAS No 60-35-5)

205

Acetonitrile

206

()

Aconitine (principal alkaloid of aconitum napellus L.) and its salts

207

()

Aconitum napellus L. (leaves, roots and galenical preparations)

208

Acrylamide,unless regulated dlsewhere in this Directive (CAS No 79-06-1)

209

Acrylonitrile (CAS No 107-13-1)

210

Adonis vernalis L. and its preparations

211

Alachlor (CAS No 15972-60-8)

212

Alanroot oil (Inula helenium) (CAS No 97676-35-2)

213

Aldrin (CAS No 309-00-2)

214

Alkali pentacyanonitrosylferrate (2-)

215

Alkali salts of pentachlorophenol (CAS No 131-52-2and7778-73-6)

216

0.1%(w/w)C1-2

Alkanes, C1-2 (CAS No 68475-57-0), if they contain > 0.1%(w/w) butadiene

217

C12-26, Alkanes, C12-26-branched and linear (CAS No 90622-53-0), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

218

0.1%(w/w)C3C1-4

Alkanes, C1-4, C3-rich (CAS No 90622-55-2), if they contain > 0.1%(w/w) butadiene

11

219

0.1%(w/w)C2-3

Alkanes, C2-3 (CAS No 68475-58-1), if they contain > 0.1%(w/w) butadiene

220

0.1%(w/w)C3-4

Alkanes, C3-4 (CAS No 68475-59-2), if they contain > 0.1%(w/w) butadiene

221

0.1%(w/w)C4-5

Alkanes, C4-5 (CAS No 68475-60-5), if they contain > 0.1%(w/w) butadiene

222

C10-13

Alkanes,C10-13 chloro (CAS No 85535-84-8)

223

Alkyne alcohols, their estersethers and salts

224

Alloclamide and its salts (2-allyloxy-4-choro-N- (2-diethylaminoethyl) benzamide)

225

(3-)

Allyl chloride (3-chloropropene) (CAS No 107-05-1)

226

Allyl glycidyl ether (CAS No 106-92-3)

227

()

Allyl isothiocyanate

228

--2-()

Alpha-piperidin-2-yl benzyl acetate laevorotatory threoform (levophacetoperane) and its salts

229

Alpha-santonin [(3S,5aR,9bS)-3,3a,4,5,5a,9b-hexahydro-3,5a,9-trimethylnaphto [1,2-b] furan-2,8-dione]

230

Aminocaproic acid (6-aminohexanoic acid) and its salts

231

Amitriptyline (5- (3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo-(a,d) cycloheptene) and its


salts

232

()

Amitrole (CAS No 61-82-5)

233

Ammi majus and its galenical preparations

234

4-,()

Amyl 4-dimethylaminobenzoate, mixed isomers (padimate A (INN))

235

Amyl nitrites

236

()

Anamirta cocculus L. (fruit)

237

Aniline, its salts and its halogenated and sulphonated derivatives

238

Anthracene oil

239

Antiandrogens of steroidal structure

240

Antibiotics

241

Antimony and its compounds

242

(,)

Apocynum cannabinum L. and its preparations

243

Apomorphine (R5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo (de,g)-quinoline-10,11-diol) and its salts

244

Arecoline (methyl 1,2,5,6-tetrahydro-1-methylnicotinate)

245

();

Aristolochic acid and its salts; Aristolochia spp and their preparations

246

[a]0.005%(w/w)C20-28 , Aromatic hydrocarbons, C20-28, polycyclic, mixed coal-tar pitch-polyethylene polypropylene

12

pyrolysis-derived(CAS No 101794-74-5), if they contain > 0.005% (w/w) benzo[a]pyrene

247

[a]0.005%(w/w)C20-28, Aromatic hydrocarbons, C20-28, polycyclic, mixed coal-tar pitch-polyethylene pyrolysis-derived (CAS
No101794-75-6), if they contain > 0.005% (w/w) benzo[a]pyrene

248

[a]0.005%(w/w)C20-28, Aromatic hydrocarbons, C20-28, polycyclic, mixed coal-tar pitch-polystyrene pyrolysis-derived (CAS No
101794-76-7), if they contain > 0.005% (w/w) benzo[a]pyrene

249

Arsenic and its compounds

250

Asbestos (CAS No 12001-28-4)

251

Atropa belladonna L. and its preparations

252

Atropine, its salts and derivatives

253

Azacyclonol (,-diphenyl--piperid-4-ylmethanol) and its salts

254

Azafenidin(CAS No 68049-83-2)

255

; 1-;

Aziridine (CAS No 151-56-4)

256

Azobenzene (CAS No 103-33-3)

257

Barbiturates

258

(, 3 6 , Barium salts, with the exception of barium sulphate, barium sulphide under the conditions laid down in
table 3, and lakes, salts and pigments prepared from the colouring agents listed in table 6
)

259

Bemegride (ethyl-3-methylglutarimide)and its salts

260

Benactyzine (2-diethylaminoethyl benzilate)

261

Bendroflumethiazide (3-benzyl-3,4-dihydro-6-trifluoromethyl-2H-1,2,4benzothiadiazine-7-sulfonamide 1,1-dioxide ) and its derivatives

262

Benomyl (CAS No 17804-35-2)

263

[e]

Benz(e)acephenanthrylene (CAS No 205-99-2)

264

[a]

Benz[a]anthracene (CAS No 56-55-3)

265

Benzatropine (tropine benzhydryl ether; 3-(diphenylmethoxy)tropane) and its salts

266

Benzazepines and benzodiazepines

267

Benzene

268

(4,4-)

Benzidine (4,4-diaminobiphenyl)

269

Benzidine acetate (CAS No 36341-27-2)

270

Benzidine based azo dyes

13

271

Benzidine dihydrochloride (CAS No 531-85-1)

272

Benzidine sulphate (CAS No 21136-70-9)

273

Benzilonium bromide (1,1-diethyl-3-hydroxypyrrolidinium bromide benzilate)

274

-2(3H)-

Benzimidazol-2(3H)-one

275

[k]

Benzo(k)fluoranthene (CAS No 207-08-9)

276

[a]

Benzo[def]chrysene (=benzo[a]pyrene) (CAS No 50-32-8)

277

[e]

Benzo[e]pyrene (CAS No 192-97-2)

278

[j]

Benzo[j]fluoranthene (CAS No 205-99-2)

279

4--3-()

Benzoates of 4-hydroxy-3-methoxycinnamyl alcohol except for normal content in natural essences used

280

2,4--

Benzyl 2,4-dibromobutanoate (CAS No 23085-60-1)

281

Benzyl butyl phthalate(CAS No 85-68-7)

282

Benzyl cyanide (CAS No 140-29-4)

283

Beryllium and its compounds

284

Betoxycaine (2-(2-diethylaminoethoxy) ethyl 3-amino-4-butoxybenzoate) and its salts

285

Bietamiverine (2-diethylaminoethyl -phenyl-1-piperidineacetate)

286

Binapacryl (CAS No 485-31-4)

287

-2-

Biphenyl-2-yl amine (CAS No 90-41-5)

288

4-

Biphenyl-4-ylamine (CAS No 92-67-1) and its salts

289

(2-)

Bis (2-ethylhexyl) phthalate (CAS No 117-81-7)

290

(2-)

Bis (2-methoxyethyl) phthalate (CAS No 117-82-8)

291

(2-)

Bis (2-methyoxyethyl) ether (CAS No 111-96-6)

292

-(2-)

Bis(2-chloroethyl) ether (CAS No 111-44-4)

293

()-(2,6--3-(-1-)-)

Bis(cyclopentadienyl)-bis(2,6-difluoro-3-(pyrrol-1-yl)-phenyl)titanium(CAS No125051-32-3)

294

A()

Bisphenol A(4,4-isopropylidenediphenol) (CAS No 80-05-7)

295

Bithionol [2,2'-thiobis (4,6-dichlorophenol)]

296

Bretylium tosilate ((o-bromobenzyl) ethyldimethylammonium p-toluenesulfonate)

297

()

Bromine, elemental

298

Bromisoval (1-(2-bromo-3-methylbutyryl) urea)

14

299

Bromoethane (CAS No 74-96-6)

300

Bromoethylene (CAS No593-60-2)

301

Bromomethane (CAS No 74-83-9)

302

Bromoxynil heptanoate (ISO)(CAS No 56634-95-8)

303

Brompheniramine (3-(p-bromophenyl)-N,N-dimethyl-3-pyrid-2-ylpropylamine) and its salts

304

Brucine

305

Buta-1,3-diene (CAS No 106-99-0)

306

0.1%(w/w)

Butane (CAS No 106-97-8), if it contains 0.1%(w/w) butadiene

307

Butanilicaine (2-butylamino-6'-chloro-o-acetotoluidide) and its salts

308

Butopiprine (2-butoxyethyl -phenyl-1-piperidineacetate) and its salts

309

Butyl glycidyl ether (CAS No 2426-08-6)

310

14

Solvent Yellow 14 (CAS No 842-07-9)

311

Cadmium and its compounds

312

( 3 )

Cantharides, cantharis vesicatoria, with the exception of cantharides tincture listed in table 3

313

Captafol (2425-06-1)

314

Captodiame (2-(p-butylmercaptobenzhydrylmercapto)-N,N-dimethylethylamine)

315

Caramiphen (2-diethylaminoethyl ester of 1-phenylcyclopentanecarboxylic acid ) and its salts

316

Carbadox (CAS No 6804-07-5)

317

()

Carbaryl (CAS No 63-25-2)

318

Carbendazim (CAS No 10605-21-7)

319

Carbon disulphide

320

Carbon monoxide (CAS No 630-08-0)

321

Carbon tetrachloride

322

Carbromal (1-(2-bromo-2-ethylbutyryl) urea)

323

Carbutamide (N'- (butylcarbamoyl) sulfanilamide; 1-butyl-3-sulfanilylurea)

324

Carisoprodol (2-carbamyloxymethyl-2-isopropylcarbamyloxymethylpentane)

325

Catalase

326

Catechol

15

327

Cells, tissues or products of human origin

328

Cephaeline and its salts

329

()

Chenopodium ambrosioides (essential oil)

330

Chinomethionate (CAS No 2439-01-2)

331

Chlordane ,pur (CAS No 57-74-9)

332

Chlordecone (CAS No 143-50-0)

333

Chlordimeform (CAS No 6164-98-3)

334

Chlorine

335

Chlormethine (2,2'-dichloro-N-methyldiethylamine; bis (2-chloroethyl) methylamine) and its salts

336

Chloroacetaldehyde (CAS No 107-20-0)

337

Chloroethane

338

Chloroform

339

Chloromethane (CAS No 74-87-3)

340

Chloromethyl methyl ether (CAS No 107-30-2)

341

Chloromezanone

342

(2--1,3-)

Chloroprene (stabilized)
(2-chlorobuta-1,3-diene) (CAS No 126-99-8)

343

Chlorothalonil (CAS No 1897-45-6)

344

(N-(3--4-)-N,N-)

Chlorotoluron(3-(3-chloro-p-tolyl)-1,1-dimethylurea) (CAS No 15545-48-9)

345

Chlorphenoxamine (2-[1-(p-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethylamine)

346

Chlorpropamide (1-(p-chlorophenylsulfonyl)-3-propylurea)

347

Chlorprothixene (trans isomer of 3-(2-chlorothioxanthen-9-ylidene) -N,N-dimethylpropylamine;


taractan) and its salts

348

Chlortalidone [2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl) benzenesulfonamide]

349

Chlorzoxazone (5-chloro-2-benzoxazolinone)

350

Chlozolinate (CAS No 84332-86-5)

351

Choline salts and their esters, e.g. Choline chloride ((2-hydroxyethyl)- trimethylammonium chloride)

352

Chromium; chromic acid and its salts

353

Chrysene (CAS No 205-99-2)

16

354

Cinchocaine (2-butoxy-N-(2-diethylamincethyl) cinchoninamide) and its salts

355

Cinchophen (2-phenylcinchoninic acid ), its salts, derivatives and salts of these derivatives

356

()

Clarified oils (petroleum),catalytic cracked (CAS No 64741-75-9)

357

()

Clarified oils(petroleum), hydrodesulfurised catalytic cracked (CAS No 68333-26-6)

358

Claviceps purpurea tul., its alkaloids and galenical preparations

359

Clofenamide (4-chloro-1,3-benzenedisulfon-amide)

360

Clofenotane; DDT (ISO)

361

[a]0.005%(w/w)

Coal liquids, liq solvent extn (CAS No 94114-48-4), if they contain > 0.005% (w/w) benzo[a]pyrene

362

[a]0.005%(w/w) Coal liquids, liq solvent extn soln(CAS No 94114-47-3), if they contain > 0.005% (w/w) benzo[a]pyrene

363

Cobalt benzenesulphonate

364

Cobalt dichloride (CAS No7646-79-9)

365

Cobalt sulphate (CAS No 10124-43-3)

366

Colchicine, its salts and derivatives

367

Colchicoside and its derivatives

368

Colchicum autumnale L. And its galenical preparations

369

CI 12075

Colouring agent CI 12075 and its lakes, pigments and salts

370

CI 12140

Colouring agent CI 12140

371

CI 13065

Colouring agent CI 13065

372

CI 15585

Colouring agent CI 15585

373

CI 26105

Colouring agent CI 26105

374

CI 42535

Colouring agent CI 42535

375

CI 42555
CI 42555-1
CI 42555-2

Colouring agent CI 42555


Colouring agent CI 42555-1
Colouring agent CI 42555-2

376

CI 42640

Colouring agent CI 42640

377

CI 45170 CI 45170: 1

Colouring agent CI 45170 and CI 45170:1

378

CI 61554

Colouring agent CI 61554

379

Coniine

17

380

()

Conium maculatum L. (fruit, powder, galenical preparations)

381

Convallatoxin

382

Costus root oil(Saussurea Lappa Clarke)

383

Coumetarol (3,3'-(2-methoxyethylidene) bis (4-hydroxycoumarin))

384

[a]0.005%(w/w)

Creosote oil, acenaphthene fraction, acenaphthene-free (CAS No 90640-85-0), if it contains > 0.005%
(w/w) benzo[a]pyrene

385

[a] 0.005%(w/w),

Creosote oil, acenaphthene fraction, wash oil, if it contains > 0.005 %(w/w)benzo[a]pyrene (CAS No
90640-84-9)

386

[a] 0.005%(w/w),

Creosote oil, high-boiling distillate, wash oil, if it contains > 0.005 %(w/w) benzo[a]pyrene (CAS No
70321-79-8)

387

[a] 0.005%(w/w)

Creosote oil, if it contains > 0.005 %(w/w) benzo[a]pyrene (CAS No 61789-28-4)

388

[a] 0.005%(w/w),

Creosote oil, low-boiling distillate, wash oil, if it contains > 0.005 %(w/w) benzo[a]pyrene (CAS No
70321-80-1)

389

[a] 0.005%(w/w)

Creosote, if it contains > 0.005 %(w/w) benzo[a]pyrene (CAS No 8001-58-9)

390

()

Croton tiglium (oil)

391

Crotonaldehyde (CAS No 4170-30-3)

392

Crude and refined coal tars

393

Curare and curarine

394

Cyclamen alcohol (CAS No 4756-19-8)

395

Cyclarbamate (1,1-bis (phenylcarbamoyloxymethyl) cyclopentane)

396

Cyclizine (1-benzhydryl-4-methylpiperazine) and its salts

397

Cycloheximide (CAS No 66-81-9)

398

Cyclomenol (2-cyclohexyl-3,5-xylenol; 2-cyclohexyl-3,5-dimethylphenol) and its salts

399

Cyclophosphamide (2[bis(2-chloroethyl) amino] tetralydro-2H-1, 3, 2- oxazaphesphorine 2-oxide) and


its salts

400

; N-

Daminozide (CAS No 1596-84-5)

401

Datura stramonium L. And its galenical preparations

402

Deanol aceglumate

403

(), :

Decamethylenebis (trimethylammonium) salts, e.g.decamethonium bromide

404

Dextromethorphan [(+)-3-methoxy-N-methylmorphinan] and its salts

18

405

Dextropropoxyphene (a-(+)-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate ester)

406

Di-allate (CAS No 2303-16-4)

407

, 4--- 2---
()

Diaminotoluene, technical product -mixture of 4-methyl-m-phenylene diamine and


2-methyl-m-phenylene diamine
methyl-phenylenediamine(CAS No 25376-45-8)

408

Diazomethane (CAS No 334-88-3)

409

[a,h]

Dibenz[a,h]anthracene (CAS No 53-70-3)

410

N-

Dibromosalicylanilides

411

Dibutyl phthalate (CAS No84-74-2)

412

()

Dichloroethanes (ethylene chlorides)

413

()

Dichloroethylenes (acetylene chlorides)

414

N-

Dichlorosalicylanilides

415

Dicoumarol (3,3-methylenebis (4-hydroxyconmarin))

416

Dieldrin (CAS No 60-57-1)

417

-4-

Diethyl 4-nitrophenyl phosphate

418

Diethyl maleate (CAS No 141-05-9)

419

Diethyl sulphate (CAS No 64-67-5)

420

Diethylcarbamoyl-chloride (CAS No 88-10-8)

421

Difencloxazine (4-(2-(p-chloro-a-phenylhenzyloxy) ethyl)morpholine)

422

Digitaline and all heterosides of digitalis purpurea L.

423

Dihydrocoumarine (CAS No 119-84-6)

424

Dihydrotachysterol (dichystrol)

425

Dimethyl citraconate (CAS No 617-54-9)

426

Dimethyl sulfoxide

427

Dimethyl sulphate (CAS No 77-78-1)

428

Dimethylamine

429

Dimethylcarbamoyl chloride (CAS No 79-44-7)

430

Dimethylformamide

431

Dimethylnitrosoamine (CAS No 62-75-9)

19

432

Dimethylsulphamoyl-chloride (CAS No 13360-57-1)

433

Dimevamide (4-dimethylamino-2,2-diphenylvaleramide) and its salts

434

Dinickel trioxide (CAS No 1314-06-3)

435

Dinitrophenol isomers

436

Dinitrotoluene, technical grade (CAS No 121-14-2)

437

Dinitrotoluene (CAS No 25321-14-6)

438

Dinocap (ISO) (CAS No 39300-45-3)

439

[2-(1-)-4,6-], Dinoseb (CAS No 88-85-7),its salts and esters with the exception of those specified elsewhere in this list

440

Dinoterb (CAS No1420-07-1),its salts and esters

441

Dioxane

442

Dioxethedrin (1-(3,4-dihydroxyphenyl)-2-ethylamino-1-propanol) and its salts

443

Diphenhydramine (2-diphenylmethoxy-N,N-dimethylaminc;dimedrol) and its salts

444

Diphenoxylate hydrochloride (ethyl ester of 1-(3-cyano-3,3-diphenylpropyl)-4- phenylisonipecotic acid)

445

Diphenylamine (CAS No 122-39-4)

446

Diphenylether; octabromo derivate (CAS No 32536-52-0)

447

Diphenylpyraline (4-benzhydryloxy-1-methylpiperidine) and its salts

448

3,3-[[1,1-]-4,4-()](4--1-)

Disodium 3,3-[[1,1-biphenyl]-4,4-diyl bis(azo)] bis (4-aminonaphthalene-1-sulphonate) (CAS No


573-58-0)

449

4--3-[[4-(2,4-)][1,1-]-4-]]-5--6-( Disodium 4-amino-3-[[4-[(2,4-diaminophenyl)azo]


[1,1-biphenyl]-4-yl]azo]-5-hydroxy-6-(phenylazo)naphthalene-2,7-disulphonate (CAS No 1937-37-7)
)-2,7-

450

[5-[[4-[[2,6--3-[(2--5-)]][1,1-]-4-] Disodium[5-[[4-[[2,6-dihydroxy-3-[(2-hydroxy-5-sulphophenyl)azo]phenyl][1,1-biphenyl]-4-yl]azo]sa
licylato(4-)]cuprate(2-) (CAS No 16071-86-6)
](4-)](2-)

451

Disperse Yellow 3 (CAS No 2832-40-8)

452

[a]0.005%(w/w)-

Distillates (coal-petroleum), condensed-ring arom(CAS No 68188-48-7), if they contain > 0.005% (w/w)
benzo[a]pyrene

453

(), Distillates (petroleum), acid-treated light (CAS No 64742-14-9), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

454

(), Distillates (petroleum), acid-treated middle (CAS No 64742-13-8), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

20

455

0.1%(w/w)C3-4

Distillates (petroleum), C3-6, piperylene-rich (CAS No 68477-35-0), if they contain > 0.1%(w/w)
butadiene

456

(), Distillates (petroleum), carbon-treated light paraffinic (CAS No 100683-97-4), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

457

(), Distillates (petroleum), catalytic reformer fractionator residue, high-boiling (CAS No 68477-29-2),
except if the full refining history is known and it can be shown that the substance from which it is

produced is not a carcinogen

458

(), Distillates (petroleum), catalytic reformer fractionator residue, intermediate-boiling (CAS No


68477-30-5), except if the full refining history is known and it can be shown that the substance from

which it is produced is not a carcinogen

459

(), Distillates (petroleum), catalytic reformer fractionator residue, low-boiling (CAS No 68477-31-6),
except if the full refining history is known and it can be shown that the substance from which it is

produced is not a carcinogen

460

(), Distillates (petroleum), catalytic reformer, heavy arom conc CAS No 91995-34-5), except if the full
refininghistory is known and it can be shown that the substance from which it is produced is not a carcin

ogen

461

(), Distillates (petroleum), chemically neutralised middle (CAS No 64742-30-9), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

462

3%(w/w)()

Distillates (petroleum), clay-treated heavy naphthenic (CAS No 64742-44-5), if they contain > 3 %
(w/w) DMSO extract

463

3%(w/w)()

Distillates (petroleum), clay-treated heavy paraffinic (CAS No 64742-36-5), if they contain > 3 % (w/w)
DMSO extract

464

3%(w/w)()

Distillates (petroleum), clay-treated light naphthenic (CAS No 64742-45-6), if they contain > 3 % (w/w)
DMSO extract

465

3%(w/w)()

Distillates (petroleum), clay-treated light paraffinic (CAS No 64742-37-6), if they contain > 3 % (w/w)
DMSO extract

466

(), Distillates (petroleum), clay-treated middle (CAS No 64742-38-7), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

467

3%(w/w)( Distillates (petroleum), complex dewaxed heavy paraffinic (CAS No 90640-91-8), if they contain > 3 %
(w/w) DMSO extract
)

468

3%(w/w)( Distillates (petroleum), complex dewaxed light paraffinic (CAS No 90640-92-9), if they contain > 3 %
(w/w) DMSO extract
)

469

3%(w/w)()

Distillates (petroleum), dewaxed heavy paraffinic, hydrotreated (CAS No 91995-39-0) if they contain >
3 % (w/w) DMSO extract

470

3%(w/w)()

Distillates (petroleum), dewaxed light paraffinic, hydrotreated (CAS No 91995-40-3), if they contain > 3

21

% (w/w) DMSO extract

471

3%(w/w)()

Distillates (petroleum), heavy hydrocracked (CAS No 64741-76-0), if they contain > 3 % (w/w) DMSO
extract

472

(), Distillates (petroleum), highly refined middle (CAS No 90640-93-0), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

473

3%(w/w)( Distillates (petroleum), hydrocracked solvent-refined light (CAS No 97488-73-8), if they contain > 3 %
(w/w) DMSO extract
)

474

3%(w/w) Distillates (petroleum), hydrocracked solvent-refined, dewaxed (CAS No 91995-45-8), if they contain >
3 % (w/w) DMSO extract
()

475

()

Distillates (petroleum), hydrodesulfurised full-range middle (CAS No 101316-57-8)

476

()

Distillates (petroleum), hydrodesulfurised heavy catalytic cracked (CAS No 68333-28-8)

477

()

Distillates (petroleum), hydrodesulfurised intermediate catalytic cracked (CAS No 68333-27-7)

478

(), Distillates (petroleum), hydrodesulfurised middle (CAS No 64742-80-9), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

479

3%(w/w)()

Distillates (petroleum), hydrotreated heavy naphthenic (CAS No 64742-52-5), if they contain > 3%
(w/w) DMSO extract

480

3%(w/w)()

Distillates (petroleum), hydrotreated heavy paraffinic (CAS No 64742-54-7), if they contain > 3 %
(w/w) DMSO extract

481

3%(w/w)()

Distillates (petroleum), hydrotreated light naphthenic (CAS No 64742-53-6), if they contain > 3 %
(w/w) DMSO extract

482

3%(w/w)()

Distillates (petroleum), hydrotreated light paraffinic (CAS No 64742-55-8), if they contain > 3 % (w/w)
DMSO extract

483

(), Distillates (petroleum), hydrotreated middle (CAS No 64742-46-7), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

484

(), Distillates (petroleum), intermediate paraffinic, carbon-treated (CAS No 100683-98-5), except if the full
refining history is known and it can be shown that the substance from which it is produced is not a

carcinogen

485

(), Distillates (petroleum), intermediate paraffinic, clay-treated (CAS No 100683-99-6), except if the full
refining history is known and it can be shown that the substance from which it is produced is not a

carcinogen

486

()

487

3%(w/w) Distillates (petroleum), solvent dewaxed heavy paraffinic, clay-treated (CAS No 90640-94-1), if they
contain> 3 % (w/w) DMSO extract
()

Distillates (petroleum), light paraffinic (CAS No 64741-50-0)

22

488

3%(w/w) Distillates (petroleum), solvent dewaxed light paraffinic, clay-treated (CAS No 90640-96-3), if they
contain > 3 % (w/w) DMSO extract
()

489

3%(w/w)( Distillates (petroleum), solvent dewaxed light paraffinic, hydrotreated (CAS No 90640-97-4), if they
contain> 3 % (w/w) DMSO extract
)

490

3%(w/w)() Distillates (petroleum), solvent-dewaxed heavy naphthenic (CAS No 64742-63-8), if they contain > 3 %
(w/w) DMSO extract

491

3%(w/w)() Distillates (petroleum), solvent-dewaxed heavy paraffinic (CAS No 64742-65-0), if they contain > 3 %
(w/w) DMSO extract

492

3%(w/w)() Distillates (petroleum), solvent-dewaxed light naphthenic (CAS No 64742-64-9), if they contain > 3 %
(w/w) DMSO extract

493

3%(w/w)() Distillates (petroleum), solvent-dewaxed light paraffinic (CAS No 64742-56-9), if they contain > 3 %
(w/w) DMSO extract

494

3%(w/w)() Distillates (petroleum), solvent-refined heavy naphthenic (CAS No 64741-96-4), if they contain > 3 %
(w/w) DMSO extract

495

3%(w/w)() Distillates (petroleum), solvent-refined heavy paraffinic (CAS No 64741-88-4), if they contain > 3 %
(w/w) DMSO extract

496

3%(w/w)( Distillates (petroleum), solvent-refined hydrocracked light (CAS No 94733-09-2), if they contain > 3 %
(w/w) DMSO extract
)

497

3%(w/w)()

498

3%(w/w)( Distillates (petroleum), solvent-refined hydrotreated heavy, hydrogenated (CAS No 94733-08-1), if they
contain> 3 % (w/w) DMSO extract
)

499

3%(w/w)() Distillates (petroleum), solvent-refined light naphthenic (CAS No 64741-97-5), if they contain > 3 %
(w/w) DMSO extract

500

3%(w/w) Distillates (petroleum), solvent-refined light naphthenic, hydrotreated (CAS No 91995-54-9), if they
contain> 3 % (w/w) DMSO extract
()

501

3%(w/w)() Distillates (petroleum), solvent-refined light paraffinic (CAS No 64741-89-5), if they contain > 3%
(w/w) DMSO extract

502

(), Distillates (petroleum), solvent-refined middle (CAS No 64741-91-9), except if the full refining history
is known and it can be shown that the substance from which it is produced is not a carcinogen

503

(), Distillates (petroleum), sweetened middle (CAS No 64741-86-2), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

Distillates (petroleum), solvent-refined hydrogenated heavy (CAS No 97488-74-9), if they contain > 3 %
(w/w) DMSO extract

23

504

()

Distillates (petroleum),acid-treated heavy naphthenic (CAS No 64742-18-3)

505

()

Distillates (petroleum),acid-treated heavy paraffinic (CAS No 64742-20-7)

506

()

Distillates (petroleum),acid-treated light naphthenic (CAS No 64742-19-4)

507

()

Distillates (petroleum),acid-treated light paraffinic (CAS No 67742-21-8)

508

()

Distillates (petroleum),chemically neutralized light naphthenic (CAS No 64742-03-6)

509

()

Distillates (petroleum),chemically neutralized light paraffinic (CAS No 64742-28-5)

510

()

Distillates (petroleum),cracked steam-cracked petroleum distillates(CAS No 68477-38-3)

511

()

Distillates (petroleum),heavy naphthenic (CAS No 64741-53-3)

512

()

Distillates (petroleum),heavy paraffinic (CAS No 64741-51-1)

513

()

Distillates (petroleum),heavy thermal cracked (CAS No 64741-81-7)

514

()

Distillates (petroleum),heavy,catalytic cracked (CAS No 64741-61-3)

515

()

Distillates (petroleum),heavy,steam-cracked (CAS No 101631-14-5)

516

()

Distillates (petroleum),hydrodesulfurised light catalytic cracked (CAS No 68333-25-5)

517

()

Distillates (petroleum),hydrodesulfurised middle coker (CAS No 101316-59-0)

518

()

Distillates (petroleum),hydrodesulfurised thermal cracked middle (CAS No 85116-53-6)

519

()

Distillates (petroleum),intermediate catalytic cracked,thermally degraded (CAS No 92201-59-7)

520

()

Distillates (petroleum),intermediate vacuum(CAS No 70592-76-6)

521

()

Distillates (petroleum),light catalytic cracked (CAS No 64741-59-9)

522

()

Distillates (petroleum),light catalytic cracked,thermally degraded (CAS No 92201-60-0)

523

Distillates (petroleum),light hydrocracked (CAS No 64741-77-1)

524

()

Distillates (petroleum),light naphthenic (CAS No 64741-52-2)

525

()

Distillates (petroleum),light steam-cracked naphtha (CAS No 68475-80-9)

526

()

Distillates (petroleum),light thermal cracked (CAS No 64741-82-8)

527

()

Distillates (petroleum),light vacuum(CAS No 70592-77-7)

528

()

Distillates (petroleum),petroleum residues vacuum(CAS No 68955-36-2)

529

()

Distillates (petroleum),vacuum (CAS No 70592-78-8)

530

()

Distillates(petroleum),chemically neutralized heavy naphthenic (CAS No 64742-34-3)

531

()

Distillates(petroleum),chemically neutralized heavy paraffinic (CAS No 64742-27-4)

24

532

()

Distillates(petroleum),intermediate catalytic cracked (CAS No 64741-60-2)

533

Disulfiram (tetraethylthiuram disulfide; bis (diethylthiocarbamyl) disulfide); thiram(ISO)

534

-2,2-- 1,1()(+ Dithio-2,2-bispyridine-dioxide 1,1(additive with trihydrated magnesium sulphate)-(pyrithione


disulphide+magnesium sulphate)
)

535

Diuron (CAS No 330-54-1)

536

Divanadium pentaoxide (CAS No 1314-62-1)

537

4,6-

DNOC (CAS No534-52-1)

538

[5.2.1.0 .0 .0 ]

Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane (CAS No 2385-85-5)

539

Doxylamine (2-[-(2-dimethylaminoethoxy)--methylbenzyl] pyridine; histadoxylamine) and its salts

540

Emetine, its salts and derivatives

541

Ephedrine and its salts

542

Epinephrine (3,4-dihydroxy--methylaminomethylbenzyl alcohol; adrenaline)

543

Epoxiconazole (CAS No 133855-98-8)

544

()

(Epoxyethyl)benzene (CAS No 96-09-3)

545

( D2 D3)

Ergocalciferol and cholecalciferol (vitamins D2 and D3)

546

Erionite (CAS No 12510-42-8)

547

()

Eserine or physostigmine and its salts

548

4-( 5 )

Esters of 4-aminobenzoic acid, with the free amino group, with the exception of that given in table 5

549

Ethionamide (2-ethylisonicotinthioamide; -ethylisonicotinic thioamide; 2-ethyl-4thiocarbamoylpyridine)

550

Ethoheptazine (4-carbethoxy-1-methyl-4-phenylhexamethylenimine) and its salts

551

Ethyl acrylate (CAS No 140-88-5)

552

(4--2--1--3-)

Ethyl bis (4-hydroxy-2-oxo-1-benzopyran-3-yl) acetate and salts of the acid

553

Ethylene glycol dimethyl ether (CAS No 110-71-4)

554

Ethylene oxide

555

Ethylphenacemide (1-(2-phenylbutyryl) urea)

556

[a]0.005%(w/w)

Extract residues (coal), brown (CAS No 91697-23-3), if they contain > 0.005% (w/w) benzo[a]pyrene

[a] 0.005%(w/w),

Extract residues (coal), creosote oil acid, wash oil extract residue, if it contains > 0.005 %(w/w)
benzo[a]pyrene (CAS No 122384-77-4)

557

2,6

3,9

5,8

25

558

3%(w/w) Extracts (petroleum), heavy naphthenic distillate solvent, arom conc (CAS No 68783-00-6), if they
contain> 3 % (w/w) DMSO extract
()

559

3%(w/w) Extracts (petroleum), heavy naphthenic distillate solvent, hydrodesulfurised (CAS No 93763-10-1), if
they contain > 3 % (w/w) DMSO extract
()

560

3%(w/w)( Extracts (petroleum), heavy naphthenic distillate solvent, hydrotreated (CAS No 90641-07-9), if they
contain> 3 % (w/w) DMSO extract
)

561

3%(w/w) Extracts (petroleum), heavy paraffinic distillate solvent, clay-treated (CAS No 92704- 08-0), if they
contain > 3 % (w/w) DMSO extract

562

3%(w/w)( Extracts (petroleum), heavy paraffinic distillate solvent, hydrotreated (CAS No 90641-08-0), if they
contain> 3 % (w/w) DMSO extract
)

563

3%(w/w) Extracts (petroleum), heavy paraffinic distillates, solvent-deasphalted (CAS No 68814-89-1), if they
contain> 3 % (w/w) DMSO extract
()

564

3%(w/w)( Extracts (petroleum), hydrotreated light paraffinic distillate solvent (CAS No 91995- 73-2), if they
contain > 3 % (w/w) DMSO extract
)

565

3%(w/w) Extracts (petroleum), light naphthenic distillate solvent, hydrodesulfurised (CAS No 91995-75-4), if they
contain> 3 % (w/w) DMSO extract
()

566

3%(w/w) Extracts (petroleum), light paraffinic distillate solvent, acid-treated (CAS No 91995-76-5), if they
contain > 3 % (w/w) DMSO extract
()

567

3%(w/w) Extracts (petroleum), light paraffinic distillate solvent, carbon-treated (CAS No 100684-02-4), if they
contain> 3 % (w/w) DMSO extract
()

568

3%(w/w) Extracts (petroleum), light paraffinic distillate solvent, clay-treated (CAS No 100684- 03-5), if they
contain > 3 %(w/w) DMSO extract
()

569

3%(w/w) Extracts (petroleum), light paraffinic distillate solvent, hydrodesulfurised (CAS No 91995-77-6), if they
contain> 3 % (w/w) DMSO extract
()

570

3%(w/w)( Extracts (petroleum), light paraffinic distillate solvent, hydrotreated (CAS No 90641-09-1), if they
contain > 3 % (w/w) DMSO extract
)

571

3%(w/w) Extracts (petroleum), light vacuum gas oil solvent, clay-treated (CAS No 100684-05-7), if they contain >
3 % (w/w) DMSO extract
()

572

3%(w/w) Extracts (petroleum), light vacuum gas oil solvent, hydrotreated (CAS No 91995-79-8), if they contain >
3 % (w/w) DMSO extract
()

573

3%(w/w) Extracts (petroleum), light vacuum, gas oil solvent, carbon-treated (CAS No 100684-04-6), if they
contain > 3 % (w/w) DMSO extract
()

26

574

3%(w/w) Extracts (petroleum), solvent-dewaxed heavy paraffinic distillate solvent, hydrodesulfurised (CAS No
93763-11-2), if they contain > 3 % (w/w) DMSO extract

575

3%(w/w) Extracts (petroleum), solvent-refined heavy paraffinic distillate solvent (CAS No 68783-04-0), if they
contain> 3 % (w/w) DMSO extract
()

576

()

Extracts (petroleum),heavy naphthenic distillate solvent (CAS No 64742-11-6)

577

()

Extracts (petroleum),heavy paraffinic distillate solvent (CAS No 64742-04-7)

578

()

Extracts (petroleum),light naphthenic distillate solvent (CAS No 64742-03-6)

579

()

Extracts (petroleum),light paraffinic distillate solvent (CAS No 64742-05-8)

580

()

Extracts (petroleum),light vacuum gas oil solvent (CAS No 91995-78-7)

581

Fenadiazole (o-(1,3,4-oxadiazol-2-yl) phenol)

582

Fenarimol (CAS No 60168-88-9)

583

Fenozolone (2-ethylamino-5-phenyl-2-cxazolin-4-one)

584

Fenpropimorph (CAS No 67564-91-4)

585

Fenthion (CAS No 55-38-9)

586

Fentin acetate (CAS No 900-95-8)

587

Fentin hydroxide (CAS No 76-87-9)

588

Fenyramidol [-(2-pyridylaminomethyl) benzyl alcohol]

589

Fig leaf absolute (Ficus carica) (CAS No 68916-52-9)

590

Fluanisone (4'-fluoro-4-[4-(o-methoxyphenyl) piperazin-1-yl] butyrophenone)

591

Fluazifop-buty1(CAS No 69806-50-4)

592

(; ; )

Fluazifo-P-butyl (CAS No 79241-46-6)

593

Flumioxazin (CAS No 103361-09-07)

594

Fluoresone (ethyl p-fluorophenyl sulfone)

595

Fluorouracil (5-fluorouracil)

596

Flusilazole (CAS No 85509-19-9)

597

3%(w/w)()

Foots oil (petroleum) (CAS No 64742-67-2), if it contains > 3 % (w/w) DMSO extract

598

3%(w/w)()

Foots oil (petroleum), acid-treated (CAS No 93924-31-3), if it contains > 3 % (w/w) DMSO extract

599

3%(w/w)()

Foots oil (petroleum), carbon-treated (CAS No 97862-76-5), if it contains > 3 % (w/w) DMSO extract

600

3%(w/w)()

Foots oil (petroleum), clay-treated (CAS No 93924-32-4), if it contains > 3 % (w/w) DMSO extract

27

601

3%(w/w)()

Foots oil (petroleum), hydrotreated (CAS No 92045-12-0), if it contains > 3 % (w/w) DMSO extract

602

3%(w/w)()

Foots oil (petroleum), silicic acid-treated (CAS No 97862-77-6), if it contains > 3 % (w/w) DMSO
extract

603

Formamide (CAS No 75-12-7)

604

0.1%(w/w),

Fuel gases, crude oil distillates (CAS No 68476-29-9), if they contain > 0.1%(w/w) butadiene

605

Fuel oil, No 6(CAS No 68553-00-4)

606

Fuel oil, No.4 (CAS No 68476-31-3)

607

Fuel oil, residual (CAS No 68476-33-5)

608

Fuel oil, residues-straight-run gas oils, high-sulfur (CAS No 68476-32-4)

609

0.1%(w/w)

Fuel-gases (CAS No 68476-26-6), if they contain > 0.1%(w/w) butadiene

610

, Fuels, diesel (CAS No 68334-30-5), except if the full refining history is known and it can be shown that
the substance from which it is produced is not a carcinogen

611

Fuels, diesel, coal solvent extn., hydrocracked hydrogenated (CAS No 94114-59-7)

612

Fuels, diesel, No.2 (CAS No 68476-34-6)

613

Fuels,jet aircraft,coal solvent extn., hydrocracked hydrogenated (CAS No 94114-58-6)

614

Fues oil, heavy, high-sulfur (CAS No 92045-14-2)

615

Fues oil, No.2 (CAS No 68476-30-2)

616

Furan (CAS No 110-00-9)

617

Furazolidone (3-(5-nitro-2-furfurylideneamino)-2-oxazolidinone)

618

,:

Furfuryltrimethylammonium salts, e.g.furtrethonium iodide

619

(: , 8-(), 5- Furocoumarines (e.g. Trioxysalan , 8-methoxypsoralen, 5-methoxypsoralen) except for normal content in
()), natural essences used. In sun protection and in bronzing products, furocoumarines shall be below 1
mg/kg.
, 1mg/kg.

620

Galantamine (1, 2, 3, 4, 6, 7, 7a, 11c-octahydro-9-methoxy-2-methylbenzofuro- (4, 3, 2- e, f, g) (2)


benzazocin-2-ol)

621

Gallamine triethiodide (1,2,3-tris(2-diethylaminoethoxy) benzene trethiodide)

622

(), Gas oils (petroleum), acid-treated (CAS No 64742-12-7), except if the full refining history is known and
it can be shown that the substance from which it is produced is not a carcinogen

623

(), Gas oils (petroleum), chemically neutralised (CAS No 64742-29-6), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

28

624

()

625

(), Gas oils (petroleum), hydrodesulfurised (CAS No 64742-79-6), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

Gas oils (petroleum), heavy atmospheric (CAS No 68783-08-4)

626

(), Gas oils (petroleum), solvent-refined (CAS No 64741-90-8), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

627

()

Gas oils (petroleum),heavy,vacuum (CAS No 64741-57-7)

628

()

Gas oils (petroleum),hydrodesulfurised coker heavy vacuum (CAS No 85117-03-9)

629

()

Gas oils (petroleum),hydrodesulfurised heavy vacuum (CAS No 64742-086-5)

630

()

Gas oils (petroleum),hydrotreated vacuum (CAS No 64742-59-2)

631

()

Gas oils (petroleum),light vacuum,thermal-cracked hydrodesulfurised (CAS No 97926-59-5)

632

()

Gas oils (petroleum),steam-cracded (CAS No 68527-18-4)

633

()

Gas oils (petroleum),thermal-cracked,hydrodesulfurised (CAS No 92045-29-9)

634

, Gas oils, hydrotreated (CAS No 97862-78-7), except if the full refining history is known and it can be
shown that the substance from which it is produced is not a carcinogen

635

, Gas oils, paraffinic (CAS No 93924-33-5), except if the full refining history is known and it can be
shown that the substance from which it is produced is not a carcinogen

636

0.1%(w/w)()

Gases (petroleum), alkylation feed (CAS No 68606-27-9), if they contain > 0.1%(w/w) butadiene

637

0.1%(w/w)()

Gases (petroleum), amine system feed (CAS No 68477-65-6), if they contain > 0.1%(w/w) butadiene

638

0.1%(w/w)()

Gases (petroleum), benzene unit hydrodesulferised off (CAS No 68477-66-7), if they contain >
0.1%(w/w) butadiene

639

0.1%(w/w)(), Gases (petroleum), benzene unit hydrotreater depentaniser overheads (CAS No 68602-82-4), if they
contain> 0.1%(w/w)butadiene

640

0.1%(w/w)()

Gases (petroleum), benzene unit recycle, hydrogen-rich (CAS No 68477-67-8), if they contain >
0.1%(w/w) butadiene

641

0.1%(w/w)(),

Gases (petroleum), blend oil, hydrogen-nitrogen-rich (CAS No 68477-68-9), if they contain >
0.1%(w/w) butadiene

642

0.1%(w/w)(),

Gases (petroleum), butane splitter overheads (CAS No 68477-69-0), if they contain > 0.1%(w/w)
butadiene

643

0.1%(w/w)C1-5()

Gases (petroleum), C1-5, wet (CAS No 68602-83-5), if they contain > 0.1%(w/w) Butadiene

644

0.1%(w/w)C2-3()

Gases (petroleum), C2-3 (CAS No 68477-70-3), if they contain > 0.1%(w/w) butadiene

645

0.1%(w/w)C2-4()

Gases (petroleum), C2-4, sweetened (CAS No 68783-65-3), if they contain > 0.1%(w/w) butadiene

29


646

0.1%(w/w)C2()

Gases (petroleum), C2-return stream (CAS No 68477-84-9), if they contain > 0.1%(w/w) butadiene

647

0.1%(w/w)C3-4()

Gases (petroleum), C3-4 (CAS No 68131-75-9), if they contain > 0.1%(w/w) butadiene

648

0.1%(w/w)C3-4()

Gases (petroleum), C3-4, isobutane-rich (CAS No 68477-33-8), if they contain > 0.1%(w/w) butadiene

649

0.1%(w/w)-C3-5()

Gases (petroleum), C3-5 olefinic-paraffinic alkylation feed (CAS No 68477-83-8), if they contain >
0.1%(w/w) butadiene

650

0.1%(w/w)C4()

Gases (petroleum), C4-rich (CAS No 68477-85-0), if they contain > 0.1%(w/w) butadiene

651

0.1%(w/w)C6-8()

Gases (petroleum), C6-8 catalytic reformer (CAS No 68477-81-6), if they contain > 0.1%(w/w) butadiene

652

0.1%(w/w)C6-8()

Gases (petroleum), C6-8 catalytic reformer recycle (CAS No 68477-80-5), if they contain > 0.1%(w/w)
butadiene

653

0.1%(w/w)C6-8()

Gases (petroleum), C6-8 catalytic reformer recycle, hydrogen-rich (CAS No 68477-82-7), if they contain
> 0.1%(w/w)butadiene

654

0.1%(w/w)(), Gases (petroleum), catalytic cracked naphtha debutanizer (CAS No 68952-76-1), if they contain >
0.1%(w/w) butadiene

655

0.1%(w/w)C3(), Gases (petroleum), catalytic cracked naphtha depropaniser overhead, C3-rich acid-free (CAS No
68477-73-6), if they contain > 0.1%(w/w) butadiene

656

0.1%(w/w)(),

Gases (petroleum), catalytic cracked overheads (CAS No 68409-99-4), if they contain > 0.1%(w/w)
butadiene

657

0.1%(w/w)()

Gases (petroleum), catalytic cracker (CAS No 68477-74-7), if they contain > 0.1%(w/w) butadiene

658

0.1%(w/w)C1-5()

Gases (petroleum), catalytic cracker, C1-5-rich (CAS No 68477-75-8), if they contain > 0.1%(w/w)
butadiene

659

0.1%(w/w)()

Gases (petroleum), catalytic cracking (CAS No 68783-64-2), if they contain > 0.1%(w/w) butadiene

660

0.1%(w/w)C2-4(), Gases (petroleum), catalytic polymd naphtha stabiliser overhead, C2-4-rich (CAS No 68477-76-9), if they
contain > 0.1%(w/w) butadiene

661

0.1%(w/w)(), Gases (petroleum), catalytic reformed naphtha stripper overheads (CAS No 68477-77-0), if they contain
> 0.1%(w/w) butadiene

662

0.1%(w/w)(), Gases (petroleum), catalytic reformed straight-run naphtha stabiliser overheads (CAS No 68513-14-4), if
they contain > 0.1%(w/w) butadiene

663

0.1%(w/w)C1-4()

664

0.1%(w/w)C4(), Gases (petroleum), catalytic-cracked gas oil depropaniser bottoms, C4-rich acid-free (CAS No
68477-71-4), if they contain > 0.1%(w/w) butadiene

665

0.1%(w/w)C3-5(), Gases (petroleum), catalytic-cracked naphtha debutaniser bottoms, C3-5-rich (CAS No 68477-72-5), if
they contain > 0.1%(w/w) butadiene

Gases (petroleum), catalytic reformer, C1-4-rich (CAS No 68477-79-2), if they contain >
0.1%(w/w)butadiene

30

666

0.1%(w/w)()

Gases (petroleum), crude distn and catalytic cracking (CAS No 68989-88-8), if they contain >
0.1%(w/w) butadiene

667

0.1%(w/w)()

Gases (petroleum), crude oil fractionation off (CAS No 68918-99-0), if they contain > 0.1%(w/w)
butadiene

668

0.1%(w/w)(),

Gases (petroleum), deethaniser overheads (CAS No 68477-86-1), if they contain > 0.1%(w/w) butadiene

669

0.1%(w/w)()

Gases (petroleum), dehexaniser off (CAS No 68919-00-6), if they contain > 0.1%(w/w)butadiene

670

0.1%(w/w)(),

Gases (petroleum), deisobutaniser tower overheads (CAS No 68477-87-2), if they contain >
0.1%(w/w)butadiene

671

0.1%(w/w),

Gases (petroleum), depropaniser bottoms fractionation off (CAS No 68606-34-8), if they contain >
0.1%(w/w) butadiene

672

0.1%(w/w)(),

Gases (petroleum), depropaniser dry, propene-rich (CAS No 68477-90-7), if they contain >
0.1%(w/w)butadiene

673

0.1%(w/w)(),

Gases (petroleum), depropaniser overheads (CAS No 68477-91-8), if they contain > 0.1%(w/w)
butadiene

674

0.1%(w/w),

Gases (petroleum), distillate unifiner desulfurisation stripper off (CAS No 68919-01-7), if they contain >
0.1%(w/w) butadiene

675

0.1%(w/w)(),

Gases (petroleum), dry sour, gas-concn- unit-off (CAS No 68477-92-9), if they contain > 0.1%(w/w)
butadiene

676

0.1%(w/w)() Gases (petroleum), fluidised catalytic cracker fractionation off (CAS No 68919-02-8) if they contain >
0.1%(w/w) butadiene

677

0.1%(w/w)() Gases (petroleum), fluidised catalytic cracker scrubbing secondary absorber off (CAS No 68919-03-9),
if they contain > 0.1%(w/w) butadiene

678

0.1%(w/w)(), Gases (petroleum), fluidised catalytic cracker splitter overheads (CAS No 68919-20-0), if they contain >
0.1%(w/w)butadiene

679

0.1%(w/w)(), Gases (petroleum), full-range straight-run naphtha dehexaniser off (CAS No 68513-15-5), if they
contain> 0.1%(w/w) butadiene

680

0.1%(w/w)()

681

0.1%(w/w)(), Gases (petroleum), gas oil diethanolamine scrubber off (CAS No 92045-15-3), if they contain >
0.1%(w/w) butadiene

682

0.1%(w/w)(),

Gases (petroleum), gas oil hydrodesulfurisation effluent (CAS No 92045-16-4), if they contain >
0.1%(w/w) butadiene

683

0.1%(w/w)(),

Gases (petroleum), gas oil hydrodesulfurisation purge (CAS No 92045-17-5), if they contain >
0.1%(w/w) butadiene

Gases (petroleum), gas concn reabsorber distn(CAS No 68477-93-0), if they contain > 0.1%(w/w)
butadiene

31

684

0.1%(w/w)(), Gases (petroleum), gas recovery plant depropaniser overheads (CAS No 68477-94-1), if they contain >
0.1%(w/w) butadiene

685

0.1%(w/w)Girbatol()

686

0.1%(w/w)(), Gases (petroleum), heavy distillate hydrotreater desulfurisation stripper off (CAS No 68919-04-0), if
they contain > 0.1%(w/w) butadiene

687

0.1%(w/w)() Gases (petroleum), hydrocracking depropaniser off, hydrocarbon-rich (CAS No 68513-16-6), if they
contain> 0.1%(w/w) butadiene

688

0.1%(w/w)()

Gases (petroleum), hydrocracking low-pressure separator (CAS No 68783-06-2), if they contain >
0.1%(w/w)butadiene

689

0.1%(w/w)()

Gases (petroleum), hydrogen absorber off (CAS No 68477-96-3), if they contain > 0.1%(w/w) butadiene

690

0.1%(w/w)(),

Gases (petroleum), hydrogenator effluent flash drum off (CAS No 92045-18-6), if they contain >
0.1%(w/w) butadiene

691

0.1%(w/w)()

Gases (petroleum), hydrogen-rich (CAS No 68477-97-4), if they contain > 0.1%(w/w) butadiene

692

0.1%(w/w)(), Gases (petroleum), hydrotreated sour kerosine depentaniser stabiliser off (CAS No 68911-58-0), if they
contain> 0.1%(w/w) butadiene

693

0.1%(w/w)(),

Gases (petroleum), hydrotreated sour kerosine flash drum (CAS No 68911-59-1), if they contain >
0.1%(w/w) butadiene

694

0.1%(w/w)-(),

Gases (petroleum), hydrotreater blend oil recycle, hydrogen-nitrogen-rich (CAS No 68477-98-5), if they
contain> 0.1%(w/w) butadiene

695

0.1%(w/w)C4() Gases (petroleum), isomerised naphtha fractionator, C4-rich, hydrogen sulfide-free (CAS No
68477-99-6), if they contain > 0.1%(w/w) butadiene

696

0.1%(w/w)()

697

0.1%(w/w)(), Gases (petroleum), light straight run gasoline fractionation stabiliser off (CAS No 68919-05-1), if they
contain> 0.1%(w/w)butadiene

698

0.1%(w/w)(), Gases (petroleum), light straight-run naphtha stabiliser off (CAS No 68513-17-7), if they contain >
0.1%(w/w) butadiene

699

0.1%(w/w)(), Gases (petroleum), naphtha steam cracking high-pressure residual (CAS No 92045-19-7), if they contain
> 0.1%(w/w)butadiene

700

0.1%(w/w)(), Gases (petroleum), naphtha unifiner desulfurisation stripper off (CAS No 68919-06-2), if they contain >
0.1%(w/w) butadiene

701

0.1%(w/w)()

Gases (petroleum), Girbatol unit feed (CAS No 68477-95-2), if they contain > 0.1%(w/w) butadiene

Gases (petroleum), light steam-cracked, butadiene conc(CAS No 68955-28-2), if they contain >
0.1%(w/w) butadiene

Gases (petroleum), oil refinery gas distn off (CAS No 68527-15-1), if they contain > 0.1%(w/w)
butadiene

32

702

0.1%(w/w)()

Gases (petroleum), platformer products separator off (CAS No 68814-90-4), if they contain >
0.1%(w/w) butadiene

703

0.1%(w/w)(), Gases (petroleum), platformer stabiliser off, light ends fractionation (CAS No 68919-07-3), if they
contain> 0.1%(w/w) butadiene

704

0.1%(w/w)(), Gases (petroleum), preflash tower off, crude distn(CAS No 68919-08-4), if they contain >
0.1%(w/w)butadiene

705

0.1%(w/w)()

Gases (petroleum), recycle, hydrogen-rich (CAS No 68478-00-2), if they contain > 0.1%(w/w) butadiene

706

0.1%(w/w)()

Gases (petroleum), refinery (CAS No 68814-67-5), if they contain > 0.1%(w/w) butadiene

707

0.1%(w/w)(),

Gases (petroleum), refinery blend (CAS No 68783-07-3), if they contain > 0.1%(w/w) butadiene

708

0.1%(w/w)(), Gases (petroleum), reformer effluent high-pressure flash drum off (CAS No 68513-18-8), if they contain
> 0.1%(w/w) butadiene

709

0.1%(w/w)(), Gases (petroleum), reformer effluent low-pressure flash drum off (CAS No 68513-19-9), if they contain
> 0.1%(w/w) butadiene

710

0.1%(w/w)()

Gases (petroleum), reformer make-up, hydrogen-rich (CAS No 68478-01-3), if they contain >
0.1%(w/w) butadiene

711

0.1%(w/w)()

Gases (petroleum), reforming hydrotreater (CAS No 68478-02-4), if they contain > 0.1%(w/w)
butadiene

712

0.1%(w/w)()

Gases (petroleum), reforming hydrotreater make-up, hydrogen-rich (CAS No 68478-04-6), if they


contain> 0.1%(w/w) butadiene

713

0.1%(w/w)-()

Gases (petroleum), reforming hydrotreater, hydrogen-methane-rich (CAS No 68478-03-5), if they


contain> 0.1%(w/w) butadiene

714

0.1%(w/w)()

Gases (petroleum), residue visbreaking off (CAS No 92045-20-0), if they contain > 0.1%(w/w)
butadiene

715

0.1%(w/w)(), Gases (petroleum), secondary absorber off, fluidised catalytic cracker overheads fractionator (CAS No
68602-84-6), if they contain > 0.1%(w/w) butadiene

716

0.1%(w/w)(), Gases (petroleum), sponge absorber off, fluidised catalytic cracker and gas oil desulfuriser overhead
fractionation(CAS No 68955-33-9), if they contain > 0.1%(w/w) butadiene

717

0.1%(w/w)C3()

718

0.1%(w/w)(), Gases (petroleum), straight-run naphtha catalytic reformer stabiliser overhead (CAS No 68955-34-0), if
they contain > 0.1%(w/w) butadiene

719

0.1%(w/w)(), Gases (petroleum), straight-run naphtha catalytic reforming off (CAS No 68919-09-5), if they contain >
0.1%(w/w) butadiene

720

0.1%(w/w)()

Gases (petroleum), steam-cracker C3-rich (CAS No 92045-22-2), if they contain > 0.1%(w/w) butadiene

Gases (petroleum), straight-run stabiliser off (CAS No 68919-10-8), if they contain > 0.1%(w/w)

33

butadiene

721

0.1%(w/w)()

Gases (petroleum), tar stripper off (CAS No 68919-11-9), if they contain > 0.1%(w/w)butadiene

722

0.1%(w/w)()

Gases (petroleum), thermal cracking distn (CAS No 68478-05-7), if they contain > 0.1%(w/w) butadiene

723

0.1%(w/w)()

Gases (petroleum), unifiner stripper off (CAS No 68919-12-0), if they contain > 0.1%(w/w) butadiene

724

Glucocorticoids

725

Glutethimide (2-ethyl-2-phenylglutarimide) and its salts

726

Glycyclamide (1-cyclohexyl-3-(p-toluenesulfonyl) urea)

727

Gold salts

728

Guaifenesin [3-(0-methoxyphenoxy)-1,2-propanediol; glyceryl guaiacolate]

729

Guanethidine (1-[2-(1-azacyclooctyl)ethyl] guanidine) and its salts

730

Haloperidol (4-[4-(p-chlorophenyl) -4-hydroxypiperidino]-4'-fluorobutyrophenone)

731

Heptachlor (CAS No 76-44-8)

732

Heptachlor-epoxide (CAS No 1024-57-3)

733

Hexachlorobenzene (CAS No 118-74-1)

734

Hexachloroethane

735

Hexaethyl tetraphosphate

736

Hexahydrocoumarin(CAS No 700-82-3)

737

(c)-1-(1H)- N--N-()

Hexahydrocyclopenta(c)pyrrole-(1H)-ammorium N-ethoxycarbonyl-N-(polylsulfonyl)azanide (EC


No418-350-1)

738

Hexamethylphosphoric-triamide (CAS No 680-31-9)

739

2-

Hexan-2-one (CAS No 591-78-6)

740

Hexane (CAS No 110-54-3)

741

Hexapropymate (1-(2-propynyl) cyclohexanol carbamate)

742

Hydrastine, hydrastinine and their salts

743

Hydrazides and their salts

744

Hydrazine, its derivatives and their salts

745

Hydroabietyl alcohol (CAS No 13393-93-6)

746

C26-55

Hydrocarbons C26-55,arom.Rich (CAS No 97722-04-8)

747

C11-17, Hydrocarbons, C11-17, solvent-extd light naphthenic (CAS No 97722-08-2), except if the full refining

34

history is known and it can be shown that the substance from which it is produced is not a carcinogen

748

C12-20, Hydrocarbons, C12-20, hydrotreated paraffinic, distn lights (CAS No 97675-86-0), except if the full
refining history is known and it can be shown that the substance from which it is produced is not a

carcinogen

749

0.1%(w/w)C1-3

750

3%(w/w)C13-27, Hydrocarbons, C13-27, solvent-extd light naphthenic (CAS No 97722-09-3), if they contain > 3 % (w/w)
DMSO extract

751

3%(w/w)C13-30, Hydrocarbons, C13-30, arom-rich, solvent-extd naphthenic distillate (CAS No 95371-04-3), if they
contain> 3 % (w/w) DMSO extract

752

0.1%(w/w)C1-4

Hydrocarbons, C1-4 (CAS No 68514-31-8), if they contain > 0.1%(w/w) butadiene

753

0.1%(w/w)C1-4

Hydrocarbons, C1-4, debutanizer fraction (CAS No 68527-19-5), if they contain > 0.1%(w/w) butadiene

754

0.1%(w/w)C1-4

Hydrocarbons, C1-4, sweetened (CAS No 68514-36-3), if they contain > 0.1%(w/w) butadiene

755

3%(w/w)C14-29, Hydrocarbons, C14-29, solvent-extd light naphthenic (CAS No 97722-10-6), if they contain > 3 % (w/w)
DMSO extract

756

C16-20, Hydrocarbons, C16-20, hydrotreated middle distillate, distn Lights (CAS No 97675- 85-9), except if the
full refining history is known and it can be shown that the substance from which it is produced is not a

carcinogen

757

3%(w/w)C16-32, Hydrocarbons, C16-32, arom rich, solvent-extd naphthenic distillate (CAS No 95371-05-4), if they
contain> 3 % (w/w) DMSO extract

758

3%(w/w)C17-30, Hydrocarbons, C17-30, hydrotreated distillates, distn Lights (CAS No 97862-82-3), if they contain > 3 %
(w/w) DMSO extract

759

3%(w/w)C17-30, Hydrocarbons, C17-30, hydrotreated solvent-deasphalted atm distn residue, distn lights (CAS No
97675-87-1), if they contain > 3 % (w/w) DMSO extract

760

3%(w/w)C17-40, Hydrocarbons, C17-40, hydrotreated solvent-deasphalted distn residue, vacuum distn lights (CAS No
97722-06-0), if they contain > 3 % (w/w) DMSO extract

761

3%(w/w)C20-50, Hydrocarbons, C20-50, residual oil hydrogenation vacuum distillate (CAS No 93924- 61-9), if they
contain > 3 % (w/w) DMSO extract

762

3%(w/w)C20-50 Hydrocarbons, C20-50, solvent dewaxed heavy paraffinic, hydrotreated (CAS No 90640-95-2), if they
contain> 3 % (w/w) DMSO extract

763

3%(w/w)C20-58

Hydrocarbons, C20-58, hydrotreated (CAS No 97926-70-0), if they contain > 3 % (w/w) DMSO extract

764

0.1%(w/w)C2-4

Hydrocarbons, C2-4 (CAS No 68606-25-7), if they contain > 0.1%(w/w) butadiene

765

0.1%(w/w)C3C2-4

Hydrocarbons, C2-4, C3-rich (CAS No 68476-49-3), if they contain > 0.1%(w/w) butadiene

Hydrocarbons, C1-3 (CAS No 68527-16-2), if they contain > 0.1%(w/w) butadiene

35

766

3%(w/w)C27-42

Hydrocarbons, C27-42, dearomatised (CAS No 97862-81-2), if they contain > 3 % (w/w) DMSO extract

767

3%(w/w)C27-42

Hydrocarbons, C27-42, naphthenic (CAS No 97926-71-1), if they contain > 3 % (w/w) DMSO extract

768

3%(w/w)C27-45

Hydrocarbons, C27-45, dearomatised (CAS No 97926-68-6), if they contain > 3 % (w/w) DMSO extract

769

3%(w/w)C27-45, Hydrocarbons, C27-45, naphthenic vacuum distn(CAS No 97862-83-4), if they contain > 3 % (w/w)
DMSO extract

770

0.1%(w/w)C3

771

Hydrocarbons, C3 (CAS No 68606-26-8), if they contain > 0.1%(w/w) butadiene

0.1%(w/w)C3-4

Hydrocarbons, C3-4 (CAS No 68476-40-4), if they contain > 0.1%(w/w) butadiene

772

0.1%(w/w), C3-4

Hydrocarbons, C3-4-rich, petroleum distillate (CAS No 68512-91-4), if they contain > 0.1%(w/w)
butadiene

773

3%(w/w)C37-65, Hydrocarbons, C37-65, hydrotreated deasphalted vacuum distn Residues (CAS No 95371-08-7), if they
contain> 3 % (w/w) DMSO extract

774

3%(w/w)C37-68, Hydrocarbons, C37-68, dewaxed deasphalted hydrotreated vacuum distn Residues (CAS No 95371-07-6),
if they contain > 3 % (w/w) DMSO extract

775

0.1%(w/w)C4

Hydrocarbons, C4 (CAS No 87741-01-3), if they contain > 0.1%(w/w) butadiene

776

0.1%(w/w)1,3-C4

Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (CAS No 95465-89-7), if they contain > 0.1%(w/w)
butadiene

777

0.1%(w/w)C4

Hydrocarbons, C4, steam-cracker distillate (CAS No 92045-23-3), if they contain > 0.1%(w/w)
butadiene

778

0.1%(w/w)C4-5

Hydrocarbons, C4-5 (CAS No 68476-42-6), if they contain > 0.1%(w/w) butadiene

779

3%(w/w), Hydrocarbons, hydrocracked paraffinic distn residues, solvent-dewaxed (CAS No 93763-38-3), if they
contain> 3 % (w/w) DMSO extract

780

C16-20 ,

Hydrocarbons,C16-20, solvent-dewaxed hydrocracked paraffinic distn.Residue (CAS No 97675-88-2)

781

,( 3 )

Hydrofluoric acid, its normal salts, its complexes and hydrofluorides with the exception of those given in
table 3

782

Hydrogen cyanide and its salts

783

8-( 3 8-)

Hydroxy-8-quinoline and its sulphate, except for the uses provided in table 3

784

Hydroxyzine [2-(2-(4-(p-chlore--phenylbenzyl)-1-piperazinyl) ethoxy)ethanol]

785

Hyoscine, its salts and derivatives

786

Hyoscyamine, its salts and derivatives

787

()

Hyoscyamus niger L. (leaves, seeds, powder and galenical preparations)

788

-2-

Imidazolidine-thione (CAS No 96-45-7)

36

789

Imperatorin (9-(3-methoxylbut-2-enyloxy)furo(3, 2-g) chromen-7-one)

790

()

Inorganic nitrites, with the exception of sodium nitrite

791

2,5-(1-)-3,6--1,4-

Inproquone (2,5-bis (1-aziridinyl)-3,6-dipropoxy-1,4-benzoquinone)

792

Iodine

793

Iodomethane (CAS No 74-88-4)

794

; 4--3,5-

Ioxynil (CAS No 1689-83-4)

795

()

Ipecacuanha (cephaelis ipecacuanha brot. And related species) (roots, powder and galenical
preparations)

796

Iprodione (CAS No 36734-19-7)

797

0.1%(w/w)

Isobutane (CAS No 75-28-5), if it contains 0.1%(w/w) butadiene

798

Isobutyl nitrite(CAS No 542-56-3)

799

Isocarboxazide (1-benzyl-2-(6-methylisoxazol-3-ylcarbonyl) hydrazine)

800

Isometheptene (6-methyl-2-methylaminohept-5-ene) and its salts

801

Isoprenaline (3,4-dihydroxy--(isopropylaminomethyl) benzyl alcohol)

802

(2--1,3-)

Isoprene (stabilized)
(2-methyl-1,3-butadiene) (CAS No 78-79-5)

803

Isosorbide dinitrate (1,4:3,6-dianhydrosorbitol 2,5-dinitrate)

804

Isoxaflutole (CAS No 141112-29-0)

805

Juniperus sabina L. (leaves, essential oil and galenical preparations)

806

Ketoconazole

807

Kresoxim-methyl (CAS No 143390-89-0)

808

Lead and its compounds

809

Lidocaine

810

Linuron (CAS No 330-55-2)

811

Lobelia inflata L. And its galenical preparations

812

Lobeline (2-(-hydroxyphenethyl)-1-methyl-6-phenacylpiperidine) and its salts

813

, Lubricating greases (CAS No 74869-21-9), except if the full refining history is known and it can be
shown that the substance from which it is produced is not a carcinogen

814

3%(w/w)

Lubricating oils (CAS No 74869-22-0), if they contain > 3 % (w/w) DMSO extract

37

815

3%(w/w)()

Lubricating oils (petroleum), base oils, paraffinic (CAS No 93572-43-1), if they contain > 3 % (w/w)
DMSO extract

816

3%(w/w) Lubricating oils (petroleum), C>25, solvent-extd, deasphalted, dewaxed, hydrogenated (CAS No
101316-69-2), if they contain > 3 % (w/w) DMSO extract
25()

817

3%(w/w) C15-30 Lubricating oils (petroleum), C15-30, hydrotreated neutral oil-based (CAS No 72623- 86-0), if they
contain > 3 % (w/w) DMSO extract
()

818

3%(w/w)C17-32 Lubricating oils (petroleum), C17-32, solvent-extd, dewaxed, hydrogenated (CAS No 101316-70-5), if
they contain > 3 % (w/w) DMSO extract
()

819

3%(w/w)C17-35 Lubricating oils (petroleum), C17-35, solvent-extd, dewaxed, hydrotreated (CAS No 92045-42-6), if they
contain> 3 % (w/w) DMSO extract
()

820

3%(w/w)( Lubricating oils (petroleum), C18-27, hydrocracked solvent-dewaxed (CAS No 97488-95-4), if they
contain > 3 % (w/w) DMSO extract
)

821

3%(w/w)C18-40, Lubricating oils (petroleum), C18-40, solvent-dewaxed hydrocracked distillate-based (CAS No


94733-15-0), if they contain > 3 % (w/w) DMSO extract

822

3%(w/w)C18-40, Lubricating oils (petroleum), C18-40, solvent-dewaxed hydrogenated raffinate-based (CAS No


94733-16-1), if they contain > 3 % (w/w) DMSO extract

823

3%(w/w)C20-35 Lubricating oils (petroleum), C20-35, solvent-extd, dewaxed, hydrogenated (CAS No 101316-71-6), if
they contain > 3 % (w/w) DMSO extract
()

824

3%(w/w)C20-50 Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based, high-viscosity (CAS No
72623-85-9), if they contain > 3 % (w/w) DMSO extract
()

825

3%(w/w) C20-50 Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based (CAS No 72623- 87-1), if they
contain > 3 % (w/w) DMSO extract
()

826

3%(w/w)C24-50 Lubricating oils (petroleum), C24-50, solvent-extd, dewaxed, hydrogenated (CAS No 101316-72-7), if
they contain > 3 % (w/w) DMSO extract
()

827

3%(w/w) Lubricating oils (petroleum), hydrocracked nonarom solvent-deparaffined (CAS No 92045-43-7), if they
contain> 3 % (w/w) DMSO extract
()

828

Lysergide (N,N-diethyllysergamide; lysergic acid diethylamide) and its salts

829

Malachite green hydrochloride (CAS No 569-64-2)


malachite green oxalate (CAS No 18015-76-4)

830

Malononitrile

831

Mannomustine (1,6-bis (2-chloroethylamino)-1,6-dideoxy-D-mannitol) and its salts

832

(3-)

Mecamylamine (3-methylaminoisobornane)

38

833

Mefeclorazine (1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl) piperazine) and its salts

834

Mephenesin (o-cresyl glyceryl ether; 3-(o-methylphenoxy)-1,2-propanediol) and its esters

835

Meprobamate (2-methyl-2-propyl-1,3-propanediol dicarbamate)

836

( 4 )

Mercury and its compounds, except those special cases included in table 4

837

Metaldehyde

838

Metamfepramone (2-dimethylaminopropiophenone) and its salts

839

Metethoheptazine (4-ethoxycarbonyl-1,3-dimethyl-4-phenylhexamethylenimine) and its salts

840

Metformin (1,1-dimethylbiguanide; N,N-dimethylguanylguanidine) and its salts

841

Methanol

842

Methapyrilene (N,N-dimethyl-N'-(2-pyridyl)-N'-(2-thenyl) ethylenediamine) and its salts

843

Metheptazine (4-carbomethoxy-1,2-dimethyl-4-phenylhexamethylenimine) and its salts

844

Methocarbamol

845

Methotrexate (N-[p-[(2, 4-diamino-6-pteridylmethyl) methylamino] benzoyl]-L-(+)-glutamic acid)

846

Methoxyacetic acid (CAS No 625-45-6)

847

Methyl isocyanate (CAS No 624-83-9)

848

-2-

Methyl trans-2-butenoate (CAS No 623-43-8)

849

((4,1-(1-(3-())-1,2--6--4- (Methylenebis(4,1-phenylenazo(1-(3-(dimethylamino)propyl)-1,2-dihydro6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl)))-1,1-dipyridinium dichloride


-2--5,3-)))-1,1-
dihydrochloride(EC No 401-500-5)

850

Methyleugenol (CAS No 93-15-2) except for normal content in the natural essences used and provided
, :
(a) 0.01%; (b) 0.004%; (c) 0.002%; that the concentration does not exceed: (a) 0.01% in fine fragrance; (b) 0.004% in eau de toilette; (c)
0.002% in fragrance cream; (d) 0.001% in rinse-off products; (e) 0.0002% in other leave-on products
(d) 0.001%; (e) 0.0002%
and oral hygiene products

851

(-ONN-)

(Methyl-ONN-azoxy)methyl acetate (CAS No 592-62-1)

852

Methyloxirane (CAS No 75-56-9)

853

Methylphenidate (methyl -phenyl-2-piperid-2-ylacetate) and its salts

854

Methyprylon (3,3-diethyl-5-methyl-2,4-piperidinedione) and its salts

855

Metronidazole

856

Metyrapone (2-methyl-1,2-dipyrid-3-yl-1-propanone)

857

, [, (Na2O + Mineral wool,with the exception of those specified elsewhere in this Annex;[Man-made vitreous

39

K2O + CaO + MgO + BaO) 18%()( (silicate) fibres with random orientation with alkaline oxide and alkali earth oxide
(Na2O+K2O+CaO+MgO+BaO)content greater than 18% by weight]
)],
858

Mofebutazone (4-butyl-1-phenyl-3,5-pyrazolidinedione)

859

Molinate (ISO) (CAS No 2212-67-1)

860

Monocrotophos (CAS No 6923-22-4)

861

Monuron (CAS No 150-68-5)

862

Morpholine (diethyleneimideoxide) and its salts

863

-4-

Morpholine-4-carbonyl chloride (CAS No 15159-40-7)

864

m-Phenylenediamine and its salts (CAS No 108-45-2)

865

m-Tolylidene diisocyanate (CAS No 26471-62-5)

866

[(-)]

[(m-Tolyloxy)methyl]oxirane (CAS No 2186-25-6)

867

, 2-(4-)-2-(1H-1,2,4--1-)

Myclobutanil, 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl methyl)hexanenitrile (CAS No 88671-89-0)

868

N-(3--3,3-)-N,N-: N-(3-carbamoyl-3,3-diphenylpropyl)-N,N-diisopropylmethylammonium salts, e.g. Isopropamide iodide

869

N-()-4--1,2-()

N-(trichloromethylthio)-4-cyclohexene-1,2-dicarboximide (captan)

870

N-()

N-(trichloromethylthio)phthalimide (CAS No 133-07-3)

871

N,N,N,N--4,4--3,3-

N,N,N,N-tetraglycidyl-4,4-diamino-3,3-diethyldiphenylmethane (CAS No 130728-76-6)

872

N,N,N,N--4,4-

N,N,N,N-tetramethyl-4,4-methylendianiline(CAS No 101-61-1)

873

N,N-(())(),:

N,N-[(methylimino) diethylene] bis (ethyldimethylammonium) salts, e.g. Azamethonium bromide

874

N,N-(),:

N,N-pentamethylenebis (trimethylammonium) salts, e.g. Pentamethonium bromide

875

N,N-(2-)-N-

N,N-bis(2-chloroethyl)methylamine N-oxide and its salts

876

N,N-

N,N-dimethylacetamide (CAS No 127-19-5)

877

N,N-

N,N-dimethylaniline (CAS No 121-69-7)

878

N,N-()

N,N-dimethylanilinium tetrakis (pentafluorophenyl)borate (CAS No 118612-00-3)

879

N,N-

N,N-dimethylformamide (CAS No 68-12-2)

880

N,N-(), :

N,N'-hexamethylenebis(trimethylammonium) salts, e g hexamethonium bromide

881

N-[2-(3--5--2-)-5-]

N-[2-(3-acetyl-5-nitrothiophen-2-ylazo)-5-diethylaminophenyl] acetamide (EC No 416-860-9)

882

N-(4---)N,N--

N-(4-chloro-o-tolyl)-N,N-dimethylformamidine monohydrochloride (CAS No 19750-95-9)

883

N-2-

N-2-naphthylaniline (CAS No 135-88-6)

40


884

N-5--2-

N-5-chlorobenzoxazol-2-ylacetamide

885

Nalorphine (N-allylnormorphine; N-allyl-N-desmethylmorphine), its salts and ethers

886

Naphazoline [2-(1-naphthylmethyl)-2-imidazoline] and its salts

887

(), Naphtha (petroleum), solvent-refined hydrodesulfurised heavy (CAS No 97488-96-5), except if the full
refining history is known and it can be shown that the substance from which it is produced is not a

carcinogen

888

Naphthalene (CAS No 91-20-3)

889

3%(w/w)()

Naphthenic oils (petroleum), catalytic dewaxed heavy (CAS No 64742-68-3), if they contain > 3 %
(w/w) DMSO extract

890

3%(w/w)()

Naphthenic oils (petroleum), catalytic dewaxed light (CAS No 64742-69-4), if they contain > 3 % (w/w)
DMSO extract

891

3%(w/w)()

Naphthenic oils (petroleum), complex dewaxed heavy (CAS No 64742-75-2), if they contain > 3 %
(w/w) DMSO extract

892

3%(w/w)()

Naphthenic oils (petroleum), complex dewaxed light (CAS No 64742-76-3), if they contain > 3 % (w/w)
DMSO extract

893

()

Narcotics, natural and synthetic controlled by the Drug Administration Law of the People's Republic of
China

894

N--N--2,5--3-

N-cyclohexyl-N-methoxy-2,5-dimethyl-3-furamide (CAS No 60568-05-0)

895

Neodymium and its salts

896

Neostigmine and its salts (e.g.neostigmine bromide )

897

Nickel (CAS No 7440-02-0)

898

Nickel carbonate (CAS No 3333-67-3)

899

Nickel dihydroxide (CAS No 12054-48-7)

900

Nickel dioxide (CAS No 12035-36-8)

901

Nickel monoxide (CAS No 1313-99-1)

902

Nickel sulphate (CAS No 7786-81-4)

903

Nickel sulphide (CAS No 16812-54-7)

904

Nicotine [3- (1-methyl-2-pyrrolidyl) pyridine] and its salts

905

Nitrobenzene

906

Nitrocresols and their alkali metal salts

907

Nitroderivatives of carbazole

41

908

Nitrofen (CAS No 1836-75-5)

909

Nitrofurantoin (1-(5-nitro-2-furfurylideneamino)-hydantoin)

910

Nitrosamines

911

Nitrosodipropylamine (CAS No 621-64-7)

912

( 1,2 ),

Nitrostilbenes, their homologues and their derivatives

913

Nitroxoline (5-nitro-8-quinolinol) and its salts

914

N-

N-Methylacetamide (CAS No 79-16-3)

915

N-

N-Methylformamide (CAS No 123-39-7)

916

4-

Nonylphenol (CAS No 25154-52-3)


4-nonylphenol, branched (CAS No 84852-15-3)

917

Noradrenaline (norepinephrine) and its salts

918

Noscapine [(-)-1-(6, 7-dimethoxy-3-phthalidyl) -8-methoxy-2-methyl-6,7methylenedioxy-1,2,3,4-tetrahydroisoquinoline] and its salts

919

O,O-()[(4--2-)]

O,O-(ethenylmethylsilylene) di[(4-methylpentan-2-one) oxime](EC No 421-870-1)

920

O,O--N--N-

O,O-diacetyl-N-allyl-N-normorphine

921

O,O--O-(4-)()

O,O-diethyl O-4-nitrophenyl phosphorothioate (parathion-ISO)

922

-(; )

o-Anisidine (CAS No 90-04-0)

923

Octamoxin (1-(1-methylheptyl)-hydrazine) and its salts

924

Octamylamine (2-isoamylamino-6-methylheptane) and its salts

925

Octodrine (1,5-dimethylhexylamine; 2-amino-6-methylheptane) and its salts

926

-()

o-Dianisidine based azo dyes

927

Oestrogens

928

Oil from the seeds of Laurus nobilis L.

929

Oleandrin

930

o-Phenylenediamine and its salts

931

o-Tolidine based dyes

932

Oxadiargyl (ISO) (CAS No 39807-15-3)

933

()[(-)], :

(Oxalylbisiminoethylene) bis [(o-chlorobenzyl) diethylammonium]salts, e.g. ambenomium chloride

934

Oxanamide (2,3-epoxy-2-ethylhexanamide) and its derivatives

42

935

, 4-(S)-

Oxiranemethanol, 4-methylbenzene-sulfonate, (S)- (CAS No 70987-78-9)

936

Oxpheneridine (ethyl ester of 1-(-hydroxyphenethyl)-4-phenylpiperidine-4- carboxylic acid) and its


salts

937

(),()

Oxybis[chloromethane],bis (Chloromethyl) ether (CAS No 542-88-1)

938

3%(w/w)()

Paraffin oils (petroleum), catalytic dewaxed heavy (CAS No 64742-70-7), if they contain > 3 % (w/w)
DMSO extract

939

3%(w/w)()

Paraffin oils (petroleum), catalytic dewaxed light (CAS No 64742-71-8), if they contain > 3 % (w/w)
DMSO extract

940

3%(w/w)()

Paraffin oils (petroleum), solvent-refined dewaxed heavy (CAS No 92129-09-4), if they contain > 3 %
(w/w) DMSO extract

941

[a]0.005%(w/w),

Paraffin waxes (coal), brown-coal high-temp tar (CAS No 92045-71-1), if they contain > 0.005% (w/w)
benzo[a]pyrene

942

[a]0.005%(w/w), Paraffin waxes (coal), brown-coal high-temp tar, carbon-treated (CAS No 97926-76-6), if they contain >
0.005% (w/w) benzo[a]pyrene

943

[a]0.005%(w/w), Paraffin waxes (coal), brown-coal high-temp tar, clay-treated (CAS No 97926-77-7), if they contain >
0.005% (w/w) benzo[a]pyrene

944

[a]0.005%(w/w), Paraffin waxes (coal), brown-coal high-temp tar, hydrotreated (CAS No 92045-72-2), if they contain >
0.005% (w/w) benzo[a]pyrene

945

[a]0.005%(w/w), Paraffin waxes (coal), brown-coal high-temp tar, silicic acid-treated (CAS No 97926-78-8), if they
contain> 0.005% (w/w) benzo[a]pyrene

946

Paramethasone (6-fluoro-16-methylpregna-1,4-diene-11,17,21-triol-3,20-dione)

947

Parethoxycaine (2-diethylaminoethyl ester of pethoxybenzoic acid) and its salts

948

p-

p-Chlorobenzotrichloride (CAS No 5216-25-1)

949

()

Pelletierine (isopelletierine) and its salts

950

Pemoline (2-amino-5-phenyl-2-oxazolin-4-one) and its salts

951

Pentachloroethane

952

Pentachlorophenol (CAS No 87-86-5)

953

Pentaerithrityl tetranitrate (pentaerythritol tetranitrate)

954

Peru balsam(INCI name: Myroxylon pereirae; CAS No 8007-00-9)

955

Petrichloral (1,1',1",1"'-(neopentanetetryltetraoxy) tetrakis (2,2,2-trichloroethanol))

956

Petrolatum (CAS No 8009-03-8), except if the full refining history is known and it can be shown that the
substance from which it is produced is not a carcinogen

43

957

(), Petrolatum (petroleum), alumina-treated (CAS No 85029-74-9), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

958

(), Petrolatum (petroleum), carbon-treated (CAS No 97862-97-0), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

959

(), Petrolatum (petroleum), clay-treated (CAS No 100684-33-1), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

960

(), Petrolatum (petroleum), hydrotreated (CAS No 92045-77-7), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

961

(), Petrolatum (petroleum), oxidised (CAS No 64743-01-7), except if the full refining history is known and
it can be shown that the substance from which it is produced is not a carcinogen

962

(), Petrolatum (petroleum), silicic acid-treated (CAS No 97862-98-1), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

963

Petroleum (CAS No 8002-05-9)

964

0.1%(w/w)

Petroleum gases, liquefied (CAS No 68476-85-7), if they contain > 0.1%(w/w) butadiene

965

0.1%(w/w)

Petroleum gases, liquefied, sweetened (CAS No 68476-86-8), if they contain > 0.1%(w/w) butadiene

966

0.1%(w/w)C4

Petroleum gases, liquefied, sweetened, C4 fraction (CAS No 92045-80-2), if they contain > 0.1%(w/w)
butadiene

967

0.1%(w/w),

Petroleum products, refinery gases (CAS No 68607-11-4), if they contain > 0.1%(w/w) butadiene

968

Phenacemide

969

Phenaglycodol

970

Phenmetrazine (3-methyl-2-phenylmorpheline) its derivatives and salts

971

Phenol (CAS No 108-95-2)

972

Phenothiazine (dibenzoparathiazine; thiodiphenylamine) and its compounds

973

Phenprobamate (3-phenylpropyl carbamate)

974

Phenprocoumon (4-hydroxy-3-(1-phenylpropyl) coumarin)

975

Phenylbutazone (4-butyl-2,2-diphenyl-3,5-pyrazolidinedione)

976

Phosphamidon (CAS No 13171-21-6)

977

Phosphorus and metal phosphides

978

Physostigma venenosum balf

979

Phytolacca spp. and their preparations

44

980

(2,4,6-)

Picric acid (2,4,6-trinitrophenol)

981

Picrotoxin

982

Pilocarpine (5-((4-ethyl-2,3,4,5-tetrahydrofuran-5-on-3-yl) methyl)-1-methylimidazole) and its salts

983

Pilocarpus jaborandi holmes and its galenical preparations

984

Pipazetate (2-(2-piperid-1-ylethoxy) ethyl ester of 10H-pyrido (3,2-b)(1,4) benzothiazine 10-carboxylic


acid ) and its salts

985

Pipradrol (-piperid-2-ylbenzhydrol) and its salts

986

Piprocurarium

987

[a] 0.005%(w/w)

Pitch (CAS No 61789-60-4) if it contains >0.005%((w/w))benzo[a]pyrene

988

[a]0.005%(w/w),

Pitch, coal tar, high-temp, heat-treated (CAS No 121575-60-8), if it contains > 0.005% (w/w)
benzo[a]pyrene

989

[a]0.005%(w/w),

Pitch, coal tar, high-temp, secondary (CAS No 94114-13-3), if it contains > 0.005% (w/w)
benzo[a]pyrene

990

[a]0.005%(w/w),

Pitch, coal tar, low-temp(CAS No 90669-57-1), if it contains > 0.005% (w/w) benzo[a]pyrene

991

[a]0.005%(w/w),

Pitch, coal tar, low-temp, heat-treated (CAS No 90669-58-2), if it contains > 0.005% (w/w)
benzo[a]pyrene

992

[a]0.005%(w/w),

Pitch, coal tar, low-temp, oxidised (CAS No 90669-59-3), if it contains > 0.005% (w/w) benzo[a]pyrene

993

[a]0.005%(w/w), -

Pitch, coal tar-petroleum (CAS No 68187-57-5), if it contains > 0.005% (w/w) benzo[a]pyrene

994

Poldine methylsulfate (2-benzilyloxymethyl-1,1-dimethylpyrrolidinium methosulfate)

995

Potassium bromate (CAS No 7758-01-2)

996

(4-)

p-Phenetidine (4-ethoxyaniline)(CAS No 156-43-4)

997

Pramocaine

998

Probenecid (p-(dipropylsulfamoyl) benzoic acid)

999

Procainamide (p-amino-N-(2-diethylaminoethyl) benzamide), its salts and derivatives

1000

Progestogens

1001

()

Propane-1,2,3-triyl trinitrate

1002

Propargite (ISO) (CAS No 2312-35-8)

1003

Propatylnitrate (2-ethyl-2-(hydroxymethyl)-1,3-propanediol trinitrate 1,1,1-trisnitrato methylpropane)

1004

Propazine (CAS No 139-40-2)

1005

Propiolactone (CAS No 57-57-8)

45

1006

Propyphenazone (4-isopropyl-2, 3-dimethyl-1-phenyl-3-pyrazolin-5-one)

1007

Propyzamide (CAS No 23950-58-5)

1008

()

Prunus laurocerasus L. ('cherry laurel water')

1009

Psilocybine [3-(2-dimethylaminoethyl) indol-4-yl dihydrogen phosphate]

1010

[(-)]

[(p-Tolyloxy)methyl]oxirane (CAS No 2186-24-5)

1011

Pymetrozine (ISO) (CAS No 123312-89-0)

1012

Pyrethrum album L. And its galenical preparations

1013

Pyrithione sodium (INNM)

1014

Pyrogallol

1015

(R)--(-)-(1R,2S)-(1,2-)

(R)--phenylethylammonium (-)-(1R,2S)-(1,2-epoxypropyl)phosphonate monohydrate (CAS No


25383-07-7)

1016

(R)-5--3-(1--2-)

(R)-5-bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole (CAS No 143322-57-0)

1017

R-1--2,3-

R-1-Chloro-2,3-epoxypropane (CAS No 51594-55-9)

1018

R-2,3--1-

R-2,3-Epoxy-1-propanol (CAS No 57044-25-4)

1019

(1)

Radioactive substances (1)

1020

C3-5(), C4 Raffinates (petroleum), steam-cracked C4 fraction cuprous ammonium acetate extn, C3-5 and C3-5 unsatd,
butadiene-free (CAS No 97722-19-5)

1021

Rauwolfia serpentina alkaloids and their salts

1022

, , ,

Reaction product of acetophenone, formaldehyde, cyclohexylamine, methanol and acetic acid(EC No


406-230-1)

1023

Residual oils (petroleum) (CAS No 93821-66-0)

1024

3%(w/w) Residual oils (petroleum), carbon-treated solvent-dewaxed (CAS No 100684-37-5), if they contain > 3
% (w/w) DMSO extract
()

1025

3%(w/w)

Residual oils (petroleum), catalytic dewaxed (CAS No 91770-57-9), if they contain > 3 % (w/w) DMSO
extract

1026

3%(w/w)()

Residual oils (petroleum), clay-treated (CAS No 64742-41-2), if they contain > 3 % (w/w) DMSO
extract

1027

3%(w/w)( Residual oils (petroleum), clay-treated solvent-dewaxed (CAS No 100684-38-6), if they contain > 3 %
(w/w) DMSO extract
)

1028

3%(w/w) Residual oils (petroleum), hydrocracked acid-treated solvent-dewaxed (CAS No 92061-86-4), if they
contain> 3 % (w/w) DMSO extract
()

46

1029

3%(w/w)()

Residual oils (petroleum), hydrotreated (CAS No 64742-57-0), if they contain > 3 % (w/w) DMSO
extract

1030

3%(w/w)()

Residual oils (petroleum), hydrotreated solvent dewaxed (CAS No 90669-74-2), if they contain > 3 %
(w/w) DMSO extract

1031

3%(w/w)()

Residual oils (petroleum), solvent deasphalted (CAS No 64741-95-3), if they contain > 3 % (w/w)
DMSO extract

1032

3%(w/w)()

Residual oils (petroleum), solvent-dewaxed (CAS No 64742-62-7), if they contain > 3 % (w/w) DMSO
extract

1033

3%(w/w)()

Residual oils (petroleum), solvent-refined (CAS No 64742-01-4), if they contain > 3 % (w/w) DMSO
extract

1034

[a] 0.005%(w/w),

Residues (coal tar), creosote oil distn., if it contains > 0.005 %(w/w) benzo[a]pyrene (CAS No
92061-93-3)

1035

[a]0.005%(w/w)

Residues (coal), liq solvent extn(CAS No 94114-46-2), if they contain > 0.005% (w/w) benzo[a]pyrene

1036

0.1%(w/w)C4

Residues (petroleum), alkylation splitter, C4-rich (CAS No 68513-66-6), if they contain > 0.1%(w/w)
butadiene

1037

()

Residues (petroleum), catalytic reformer fractionator residue distn. (CAS No 68478-13-7)

1038

()

Residues (petroleum), coker scrubber,condensed-ring-arom.-contg (CAS No 68783-13-1)

1039

()

Residues (petroleum), heavy coker and light vacuum (CAS No 68512-61-8)

1040

()

Residues (petroleum), heavy coker gas oil and vacuum gas oil (CAS No 68478-17-1)

1041

()

Residues (petroleum), light vacuum (CAS No 68512-62-9)

1042

()

Residues (petroleum), steam-cracked light (CAS No68513-69-9)

1043

()

Residues (petroleum), topping plant ,low-sulfur(CAS No 68607-30-7)

1044

()

Residues (petroleum),atm.tower (CAS No 64741-57-7)

1045

()

Residues (petroleum),atmospheric (CAS No 68333-22-2)

1046

()

Residues (petroleum),catalytic cracking (CAS No 92061-97-7)

1047

()

Residues (petroleum),catalytic reformer fractionator (CAS No 64741-67-9)

1048

()

Residues (petroleum),hydrocracked (CAS No 64741-75-9)

1049

()

Residues (petroleum),hydrodesulfurised atmospheric tower (CAS No 64742-78-5)

1050

()

Residues (petroleum),hydrogenated steam-cracked naphtha (CAS No 92062-00-5)

1051

()

Residues (petroleum),steam-cracked (CAS No 64742-90-1)

1052

()

Residues (petroleum),steam-cracked heat-soaked naphtha (CAS No 93763-85-0)

47

1053

()

Residues (petroleum),steam-cracked naphtha distn. (CAS No 92062-04-9)

1054

()

Residues (petroleum),steam-cracked,distillates (CAS No 90669-75-3)

1055

()

Residues (petroleum),steam-cracked,resinous (CAS No 68955-36-2)

1056

()

Residues (petroleum),thermal cracked (CAS No64741-80-6)

1057

()

Residues (petroleum),vacuum,light (CAS No 90669-76-4)

1058

()

Residues, steam cracked, thermally treated (CAS No 98219-64-8)

1059

Resorcinol diglycidyl ether (CAS No 101-90-6)

1060

(S)-2,3--1H--

(S)-2,3-Dihydro-1H-indole-carboxylic acid (CAS No 79815-20-6)

1061

(), [, Safrole except for normal content in the natural essences used and provided the concentration does not
: 100mg/kg; 50mg/kg( exceed: 100mg/kg in the finished product; 50mg/kg in products for dental and oral hygiene, and
provided that safrole is not present in toothpastes intended specifically for children
)]

1062

4,4-(N,N-)

1063

Salts of 4,4-carbonimidoyl bis(N,N-dimethylaniline)

O-

Salts of O-alkyldithiocarbonic acids

1064

-()

Salts of o-dianisidine

1065

()()

Schoenocaulon officinale Lind. (seeds and galenical preparations)

1066

Secondary alkyl and alkanolamine and their salts

1067

( 3 )

Selenium and its compounds with the exception of selenium disulphide under the conditions set out
under the reference in table 3

1068

Simazine (CAS No 122-34-9)

1069

(), Slack wax (petroleum) (CAS No 64742-61-6), except if the full refining history is known and it can be
shown that the substance from which it is produced is not a carcinogen

1070

(), Slack wax (petroleum), acid-treated (CAS No 90669-77-5), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

1071

(), Slack wax (petroleum), carbon-treated (CAS No 100684-49-9), except if the full refining history is
known and it can be shown that the substance from which it is produced is not a carcinogen

1072

(), Slack wax (petroleum), clay-treated (CAS No 90669-78-6), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

1073

(), Slack wax (petroleum), hydrotreated (CAS No 92062-09-4), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

1074

(), Slack wax (petroleum), low-melting (CAS No 92062-10-7), except if the full refining history is known
and it can be shown that the substance from which it is produced is not a carcinogen

48

1075

(), Slack wax (petroleum), low-melting, carbon-treated (CAS No 97863-04-2), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

1076

(), Slack wax (petroleum), low-melting, clay-treated (CAS No 97863-05-3), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

1077

(), Slack wax (petroleum), low-melting, hydrotreated (CAS No 92062-11-8), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

1078

(), Slack wax (petroleum), low-melting, silicic acid-treated (CAS No 97863-06-4), except if the full refining
history is known and it can be shown that the substance from which it is produced is not a carcinogen

1079

2-(1-)

Sodium hexacyclonate (sodium 2-(1-hydroxymethylcyclohexyl)acetate)

1080

Solanum nigrum L. And its galenical preparations

1081

Sparteine and its salts

1082

Spironolactone (17-hydroxy-7-mercapto-3-oxo-17-pregn-4-eno-21-carboxylic acid r-tactone


7-acetate)

1083

Strontium lactate

1084

Strontium nitrate

1085

Strontium polycarboxylate

1086

Strophantines, their aglucones and their respective derivatives

1087

Strophantus species and their galenical preparations

1088

Strychnine and its salts

1089

Strychnos species and their galenical preparations

1090

Substances with androgenic effect

1091

()

Succinonitrile

1092

Sulfallate (CAS No 95-06-7)

1093

Sulfinpyrazone (1,2-diphenyl-4-(2-phenylsulfinylethyl)-3,5-pyrazolidinedione)

1094

() Sulphonamides (sulphanilamide and its derivatives obtained by substitution of one or more H-atoms of
the -NH2 groups) and their salts

1095

1096

Sympathicomimetic amines acting on the central nervous system and the medicins, natural and synthetic,
controlled by the Drug Administration Law of the People's Republic of China (except caffien)
()

Sultiame (sulthiane; [2-(p-sulfamoylphenyl) tetrahydro-1,2-thiazine 1,1-dioxide])

49

1097

1098

Synthetic curarizants

0.1%(w/w), Tail gas (petroleum), catalytic cracked clarified oil and thermal cracked vacuum residue fractionation
reflux drum (CAS No 68478-21-7), if it contains > 0.1%(w/w) butadiene

1099

0.1%(w/w), Tail gas (petroleum), catalytic cracked distillate and catalytic cracked naphtha fractionation absorber
(CAS No68307-98-2), if it contains > 0.1%(w/w) butadiene

1100

0.1%(w/w), Tail gas (petroleum), catalytic cracked distillate and naphtha stabiliser (CAS No 68952-77-2), if it
contains> 0.1%(w/w) butadiene

1101

0.1%(w/w), Tail gas (petroleum), catalytic cracked naphtha stabilisation absorber (CAS No 68478-22-8), if it
contains> 0.1%(w/w) butadiene

1102

0.1%(w/w),

1103

0.1%(w/w) Tail gas (petroleum), catalytic cracker, catalytic reformer and hydrodesulferised combined fractionater
(CAS No68478-24-0), if it contains > 0.1%(w/w) butadiene

1104

0.1%(w/w), Tail gas (petroleum), catalytic hydrodesulfurised naphtha separator (CAS No 68952-79-4), if it contains
> 0.1%(w/w)butadiene

1105

0.1%(w/w), Tail gas (petroleum), catalytic polymn. naphtha fractionation stabiliser (CAS No68307-99-2), if it
contains > 0.1%(w/w) butadiene

1106

0.1%(w/w), Tail gas (petroleum), catalytic reformed naphtha fractionation stabiliser, hydrogen sulfide-free (CAS No
68308-00-9), if it contains > 0.1%(w/w) butadiene

1107

0.1%(w/w), Tail gas (petroleum), catalytic reformed naphtha fractionation stabiliser (CAS No 68478-26-2), if it
contains > 0.1%(w/w) butadiene

1108

0.1%(w/w),

Tail gas (petroleum), catalytic reformed naphtha separator (CAS No 68478-27-3), if it contains >
0.1%(w/w) butadiene

1109

0.1%(w/w),

Tail gas (petroleum), catalytic reformed naphtha stabiliser (CAS No 68478-28-4), if it contains >
0.1%(w/w) butadiene

1110

0.1%(w/w),

Tail gas (petroleum), cracked distillate hydrotreater separator (CAS No 68478-29-5), if it contains >
0.1%(w/w) butadiene

1111

0.1%(w/w), Tail gas (petroleum), cracked distillate hydrotreater stripper (CAS No 68308-01-0), if it contains >
0.1%(w/w) butadiene

1112

0.1%(w/w),

Tail gas (petroleum), gas oil catalytic cracking absorber (CAS No 68308-03-2), if it contains >
0.1%(w/w) butadiene

1113

0.1%(w/w),

Tail gas (petroleum), gas recovery plant (CAS No 68308-04-3), if it contains > 0.1%(w/w) butadiene

1114

0.1%(w/w),

Tail gas (petroleum), gas recovery plant deethaniser (CAS No 68308-05-4), if it contains > 0.1%(w/w)

Tail gas (petroleum), catalytic cracker refractionation absorber (CAS No 68478-25-1), if it contains >
0.1%(w/w)butadiene

50

butadiene

1115

0.1%(w/w), Tail gas (petroleum), hydrodesulfurised distillate and hydrodesulfurised naphtha fractionator, acid-free
(CAS No68308-06-5), if it contains > 0.1%(w/w) butadiene

1116

0.1%(w/w), Tail gas (petroleum), hydrodesulfurised straight-run naphtha separator (CAS No 68478-30-8), if it
contains> 0.1%(w/w) butadiene

1117

0.1%(w/w), Tail gas (petroleum), hydrodesulfurised vacuum gas oil stripper, hydrogen sulfide-free (CAS No
68308-07-6), if it contains > 0.1%(w/w) butadiene

1118

0.1%(w/w),

1119

0.1%(w/w), Tail gas (petroleum), light straight-run naphtha stabiliser, hydrogen sulfide-free (CAS No 68308-09-8),
if it contains > 0.1%(w/w) butadiene

1120

0.1%(w/w), - Tail gas (petroleum), propane-propylene alkylation feed prep deethaniser (CAS No 68308-11-2), if it
contains> 0.1%(w/w) butadiene

1121

0.1%(w/w), C4

Tail gas (petroleum), saturate gas plant mixed stream, C4-rich (CAS No 68478-32-0), if it contains >
0.1%(w/w) butadiene

1122

0.1%(w/w)C1-2,

Tail gas (petroleum), saturate gas recovery plant, C1-2-rich (CAS No 68478-33-1), if it contains >
0.1%(w/w) butadiene

1123

0.1%(w/w), Tail gas (petroleum), straight-run distillate hydrodesulferised, hydrogen sulfide-free (CAS No
68308-10-1), if it contains > 0.1%(w/w) butadiene

1124

0.1%(w/w),

1125

0.1%(w/w), Tail gas (petroleum), thermal cracked hydrocarbon fractionation stabiliser, petroleum coking (CAS No
68952-82-9), if it contains > 0.1%(w/w) butadiene

1126

0.1%(w/w), Tail gas (petroleum), thermal-cracked distillate, gas oil and naphtha absorber (CAS No 68952-81-8), if it
contains > 0.1%(w/w) butadiene

1127

0.1%(w/w), Tail gas (petroleum), vacuum gas oil hydrodesulferised, hydrogen sulfide-free (CAS No 68308-12-3), if
it contains > 0.1%(w/w) butadiene

1128

0.1%(w/w),

Tail gas (petroleum), vacuum residues thermal cracker (CAS No 68478-34-2), if it contains >
0.1%(w/w) butadiene

1129

Tefazoline (2-(5,6,7,8-tetrahydronaphth-1-ylmethyl )-2-imidazoline) and its salts

1130

Tellurium and its compounds

1131

Tetrabenazine(1,3,4,6,7,llb-hexahydro-3-isobutyl-9,10-dimethoxy-2H-berzo(a)quinolizin-2-one) and its


salts

Tail gas (petroleum), isomerised naphtha fractionation stabiliser (CAS No 68308-08-7), if it contains >
0.1%(w/w) butadiene

Tail gas (petroleum), straight-run naphtha hydrodesulferised (CAS No 68952-80-7), if it contains >
0.1%(w/w) butadiene

51


1132

N-

Tetrabromosalicylanilides

1133

Tetracaine (deanol p-butylaminobenzoate) and its salts

1134

Tetracarbonyl nickel (CAS No 13463-39-3)

1135

Tetrachloroethylene

1136

N-

Tetrachlorosalicylanilides

1137

Tetraethyl pyrophosphate; TEPP (ISO)

1138

(+/-)--(R)-2-[4-(6--2-)]

(+/-)-Tetrahydrofurfuryl-(R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenyloxy]propionate(CAS No
119738-06-6)

1139

-3-

Tetrahydrothiopyran-3-carboxaldehyde (CAS No 61571-06-0)

1140

Tetrahydrozoline and its salts

1141

3,3-[[1,1-]-4,4--()][5--4--2,7- Tetrasodium 3,3-[[1,1-biphenyl]-4,4-diyl bis(azo)]bis


[5-amino-4-hydroxynaphthalene-2,7-disulphonate] (CAS No 2602-46-2)

1142

Tetrylammonium bromide (tetraethylammonium bromide)

1143

Thalidomide [N-(2,6-dicxopiperid-3-yl) phthalimide] and its salts

1144

Thallium and its compounds

1145

(1) , :
12
12

(2)
(3) 2002 3
, ( 2002 3
), ,
:
200,
20 ()
NaOH(12mol/L)():
: 95 3h
: 140, 2bars (2000h Pa) 8

(1) The skull , including the brain and eyes, tonsils and spinal cord of:
bovine animals aged 12 months
ovine and caprine animals which are aged over 12 months or have a permanent incissor
tooth erupted through the gum;
(2) The spleens of ovine and caprine animals and ingredients derived therefrom
(3) Ingredients list as class 1 substances in the bullten No.3, 2002 promulgated by ministry of public
health and its salts.
However, tallow derivatives (including the substances list as class 2 ingredients in the bullten No.3,
2002 promulgated by ministry of public health) may be used provided that the following methods have
been used and strictly certified by the producer:
transesterification or hydrolysis at at least 200 and at an appropriate corresponding pressure,
for 20 minutes (glycerol, fatty acids and fatty acid esters)
saponification with NaOH 12mol/L (glycerol and soap):
batch process: at 95 for 3 hours; or
continuous process : at 140, 2 bars (2000 h pa) for 8 minutes or equivalent conditions.

1146

Thevetia neriifolia juss. Glycoside extract

1147

Thiamazole (1-methyl-2-imidazolethiol)

1148

Thioacetamide (CAS No 62-55-5)

52

1149

Thiophanate-methyl (CAS No 23564-05-8)

1150

Thiotepa [tris(1-aziridinyl) phosphine sulfide]

1151

( 3 )

Thiourea and its derivatives, with the exception of the one listed in table 3.

1152

Thiuram disulphides

1153

Thiuram monosulphides

1154

Thyropropic acid (4-(4-hydroxy-3-iodophenoxy)-3,5-diiodohydrocinnamie acid) and its salts

1155

Thyrothricine

1156

Tolboxane (5-methyl-5-propyl-2-p-tolyl-1,3,2-dioxaborinane)

1157

Tolbutamide (1-butyl-3-(p-toluenesulfonyl) urea; 1-butyl-3-tosylurea)

1158

(1:1)

Toluidene sulphate(1:1) (CAS No540-25-0)

1159

Toluidines, their isomers, salts and halogenated and sulphonated derivatives

1160

4-

Toluidium chloride (CAS No 540-23-8)

1161

[()],

[(Tolyloxy)methyl]oxirane,cresyl glycidyl ether (CAS No 26447-14-3)

1162

Toxaphene (CAS No 8001-35-2)

1163

-2-

Trans-2-heptenal (CAS No 18829-55-5)

1164

-2-

Trans-2-hexenal diethyl acetal (CAS No 67746-30-9)

1165

-2-

Trans-2-hexenal dimethyl acetal (CAS No 18318-83-7)

1166

-4--L--

Trans-4-cyclohexyl-L-proline monohydro-chloride (CAS No 90657-55-9)

1167

-4--L-

Trans-4-phenyl-L-proline(CAS No 96314-26-0)

1168

Tranylcypromine (DL-trans-2-phenylcyclopropylamine) and its salts

1169

Tretamine (2,4,6-tris (1-aziridinyl)-s-triazine; triethylenemelamine)

1170

()

Tretinoin (retinoic acid) and its salts

1171

Triamterene (2,4,7-triamino-6-phenylpteridine) and its salts

1172

Tributyl phosphate (CAS No 126-73-8)

1173

Trichlormethine (tris (2-chloroethyl) amine; 2,2',2"-trichlorotriethylamine) and its salts

1174

Trichloroacetic acid

1175

Trichloroethylene (CAS No 79-01-6)

1176

()

Trichloronitromethane (chloropicrine)

53

1177

Tridemorph (CAS No 24602-86-6)

1178

Trifluoroiodomethane (CAS No 2314-97-8)

1179

Trifluperidol (1-[3-(p-fluorobenzoyl) propyl]-4-(m-trifluoromethylpheryl)-4- piperidinol)

1180

Trinickel disulphide (CAS No 12035-72-2)

1181

(1,3,5-)

Trioxymethylene(1,3,5-trioxan) (CAS No 110-88-3)

1182

Triparanol (2-(p-chlorophenyl)-1-[p-(2-diethylaminoethoxy)phenyl-1-(p-tolyl)]ethanol)

1183

Tripelennamine [N-benzyl-N',N'-dimethyl-N-(2-pyridyl) ethylenediamine]

1184

(2-)

Tris(2-chloroethyl) phosphate (CAS No 115-96-8)

1185

(7--2-(4--2-)-3--1-)-1-

Trisodium bis (7-acetamido-2-(4-nitro-2-oxidophenylazo)-3-sulfonato-1-naphtholato)chromate (1-)(EC


No400-810-8)

1186

[4-(8--3,6--2-)-4-(6--3- Trisodium[4-(8-acetylamino-3,6-disulfonato-2-naphthylazo)-4-(6-benzoylamino-3-sulfonato-2-naphth
-2- )- -1,3,3,1- -O,O,O,O] (II) (EC No ylazo)-biphenyl-1,3,3,1-tetraolato-O,O,O,O]copper(II)(EC No 413-590-3)
413-590-3)

1187

Tritolyl phosphate

1188

Tuaminoheptane (2-aminoheptane; 2-heptylamine), its isomers and salts

1189

Urethane (CAS No 51-79-6)

1190

()

Urginea scilla stern. and its galenical preparations

1191

UVCB : -, UVCB condensation product of: tetrakis-hydroxymethylphosphonium chloride, urea and distilled
hydrogenated C16-18 tallow alkylamine (CAS No 166242-53-1)
C16-18

1192

Vaccines, toxins or serums

1193

Valinamide (CAS No 20108-78-5)

1194

Valnoctamide (2-ethyl-3-methylvaleramide)

1195

Veratrine, its salts and galenical preparations

1196

Veratrum spp. And their preparations

1197

Verbena oil (Lippia citriodora Kunth) (CAS No 8024-12-2)

1198

Vinclozolin (CAS No 50471-44-8)

1199

Vinyl chloride monomer

1200

(1,1-)

Vinylidene chloride(1,1-dichloroethylene) (CAS No 75-35-4)

1201

Warfarin (3- (-acetonylbenzyl) -4-hydroxycaumarin) and its salts

54

1202

[a]0.005%(w/w), Waste solids, coal-tar pitch coking (CAS No 92062-34-5), if they contain > 0.005% (w/w)
benzo[a]pyrene

1203

Xylidines, their isomers, salts and halogenated and sulphonated derivatives

1204

Xylometazoline [2-(4-tert-butyl-2,6-dimethylbenzyl)-2-imidazoline] and its salts

1205

Yohimbine (16-carbomethoxyyohimban-17-ol; ester of yohimbic acid) and its salts

1206

Ziram (CAS No 137-30-4)

1207

( 3 6 , Zirconium and its compounds,with the exception of the complexes listed in table 3 and of zirconium
lakes, salts and pigments of colouring agents listed in table 6
)

1208

Zoxazolamine (2-amino-5-chlorobenzoxazole)

(1) ,

(2)

55

2(2) (1)
()

()

Aconitum L, (Ranunculaceae).

Adonis L, (Ranunculaceae).

Alocasia cucullata (Lour.) Schott

Alocasia odora (Roxb.) K.Koch

Amorphophallus rivieri Durieu; Amorphophallus sinensis Belval

Anemone hupehensis Lemoine

Angelica dahurica(Fisch. ex Hoffm.) Benth. et Hook. f.

Angelica dahurica(Fisch. ex Hoffm.)Benth. et Hook. f. var. formosana(Boiss.) Shan et Yuan

Anisodus Link et Otto, (Solanaceae).

10

Areca catechu L.

11

Aristolochia delilis siel et Zuuo.

12

Aristolochia fangchi Y. C. Wu ex L. D. Chou et S. M. Hwang

13

Aristolochia manshuriensis Kom.

14

Asarum L, ( Aristolochiaceae).

15

Brassica juncea (L.) Czern. et Coss.; Sinapis alba L.

16

Brucea javanica (L.) Merr.

17

Bufo bufo gargarizans Cantor ; Bufo melanostictus Schneider

18

Catharanthus roseus (L.) G.Don

19

()

Cerbera manghas L.

20

Chelidonium majus L.

21

Chenopodium album L.

22

Clematis chinensis Osbeck; Clematis hexapetala Pall.; Clematis manshurica Rupr.

23

Convallaria keiskei Miq.

24

Coriaria sinica Maxim.

25

Corydalis incisa (Thunb.) Pers.

26

Crinum asiaticum L. var. sinicum Bak.

56

()

27

()

Crotalaria sessiliflora L.

28

Croton L, (Euphorbiaceae).

29

()

Daphne genkwa Sieb. et Zucc.

30

Datura L., (Solanaceae).

31

Derris trifoliata Lour.

32

Digitalis L, (Scrophulariaceae).

33

Dioscorea hispida Dennst.

34

Drosera peltata Sm.var.lunata (Buch.-Ham.)C.B.Clarke

35

Dryopteris crassirhizoma Nakai

36

Ephedra Tourn. ex L, (Ephedraceae).

37

Epicauta gorhami Mars.

38

Euphorbia L, (Euphorbiaceae).

39

Garcinia morella Desv.

40

Gelsemium elegans Benth.

41

Huechys sanguinea De Geer.

42

Hydnocarpus anthelmintica Pierre ; Hydnocarpus hainanensis (Merr.)Sleum.

43

Hyoscyamus niger L. (Leaves Seeds)

44

Illicium lanceolatum A.C.Smith

45

Iphigenia indica Kunth et Benth.

46

Lobelia L, (Campanulaceae).

47

Lycoris radiata Herb.

48

Lytta caraganae Pallas

49

Macleaya cordata (Willd.) R. Br.

50

Meloe coarctatus Motsch.

51

Mimosa pudica L.

52

Nerium indicum Mill.

53

Orixa japonica Thunb.

54

()

Periploca sepium Bge.

57

()

55

Pharbitis nil(L.) Choisy. ; Pharbitis purpurea (L.) Voigt

56

Phytolacca acinosa Roxb; Phytolacca americana L.

57

Pinellia ternata (Thunb.) Breit.

58

Plumbago indica L.

59

Plumbago zeylanica L.

60

Psoralea corylifolia L.

61

Ranunculus L, (Ranunculaceae).

62

Rauvolfia verticillata (Lour.)Baill.

63

Rhododendron molle G. Don

64

Rohdea japonica Roth

65

Sapium sebiferum (L.) Roxb.

66

Securinega suffruticosa (Pall.) Rehd.

67

Sophora flavescens Ait.

68

Strophanthus divaricatus (Lour.) Hook. et Arn.

69

Senecio L, (Compositae).

70

Skimmia reevesiana Fortune

71

Stellera chamaejasme L.

72

Strychnos L, (Loganiaceae).

73

Thevetia peruviana (Pers.) K. Schum.

74

Tripterygium hypoglaucum (LVL.) Hutch.

75

Tripterygium wilfordii Hook.f.

76

Typhonium giganteum Engl.

77

Veratrum L, (Liliaceae).

78

Wikstroemia indica (L.) C.A.Mey.

(1)

58

3
( INCI )

INCI

()

-
(1)

-Hydroxy acids and


their salts, esters

None

6-

6-Methyl coumarin

6-Methyl coumarin

0.003%

(1)

(1) Alkali sulphides

(1) Alkali sulfides

(2)

(2) Alkaline earth


sulphides

(2) Alkaline earth


sulfides

(C12-C22)

Alkyl(C12-C22)
trimethyl ammonium,
bromide and chloride

Alkyl(C12-C22)
trimonium bromide
and chloride

Aluminium fluoride

Aluminium fluoride

0.15%( F ),
, F
0.15%

(AlxZr(OH)yClz)

Aluminium zirconium
chloride hydroxide
complexes;AlxZr(OH)y
Clz and the aluminium
zirconium chloride
hydroxide glycine
complexes

Aluminium zirconium
chloride hydroxide
complexes
AlxZr(OH)yClz and the
aluminium zirconium
chloride hydroxide
glycine complexes

20%()

Ammonia

Ammonia

Ammonium fluoride

Ammonium fluoride

Ammonium

Ammonium

6%()

pH3.5(
)

,
3%-
-
,

2%()

pH12.7

6%()

pH12.7

(a)

(a) 0.25%

(b)

5.4%()

2 10 ;
(Al+Zr)
0.9
2.1 ;

6%( NH3 )

2%,

0.15%( F ),
, F
0.15%

0.15%( F ),

8
9

59

fluorosilicate

INCI
fluorosilicate

()

Ammonium
monofluorophosphate

Ammonium
monofluorophosphate

0.15%( F ),
, F
0.15%

,

, 2

Benzalkonium
chloride, bromide and
saccharinate

Benzalkonium
chloride, bromide and
saccharinate

(a)

(a) 3%()

(b)

(b) 0.1%()

10

, F
0.15%

11

12

(a)


C14,
0.5%(
)

15

(1) ,
(
2(1)
)

(a)

(b)

Benzoic acid
Sodium benzoate

Benzoic acid
Sodium benzoate

(a)

(a) 2.5%()

(b)

(b) 1.7%()

Benzoyl peroxide

Benzoyl peroxide

0.7%()

;
;

Benzyl alcohol

Benzyl alcohol

(1) Boric acid,


borates and
tetraborates with the
exception of
substances in table
2(1)

(1) Boric acid, borates (a)


and tetraborates with
the exception of
substances in table
2(1)

(a) 5%()

(a)
;

1.5%(
),

(a)
;

(b)

(b) 0.1%()

(b)

(b) ;

(c) (
)

(c) 3%()

(c)
;

1.5%(
),

(c)
;

13
14

60

(2)

INCI

(2) Tetraborates

(2) Tetraborates

()

(b)

(b) 8% ()

(b)

Calcium fluoride

Calcium fluoride

0.15%( F ),
, F
0.15%

Calcium hydroxide

Calcium hydroxide

(a)

(a) 7% ()

(a) ;
;
;

(b) pH

(b) pH12.7

(c) , pH

(c) pH11

Calcium
monofluorophosphate

Calcium
monofluorophosphate

0.15%( F ),
, F
0.15%

Cantharides tincture

None

()

1%

Hexadecyl
ammonium fluoride

Cetylamine
hydrofluoride

0.15%( F ),
, F
0.15%

Tosylchloramide
sodium

Chloramine T

Chlorates of alkali
metals

Chlorates of alkali
metals

(a)
(b)

(a) 5%
(b) 3%

2,4-Diamino-pyrimid
ine-3-oxide

Diaminopyrimidine
oxide

1.5%

18

19

20

23

(a)

(a) 18% ()

17

22

(a)

(a)

16

21

0.2%

61

(b) ;
;

;
; ;

INCI

()


0.2%

Dichloromethane

Dichloromethane

35%( 1,1,1-
35%)

25

Dichlorophen

Dichlorophen

0.5%

()

1,3-Bis(hydroxymeth
yl)imidazolidine-2-th
ione

Dimethylol ethylene
thiourea

(a)

(a) 2%

(a)

26

(b) (, )

(b) 2%

(b) pH
4

Etidronic acid and its


salts(1-hydroxyethyli
dene-di-phosphonic
acid and its salts)

Etidronic acid and its


salts

(a)

(a) 1.5% ()

(b) ,

(b) 2% ()

Fatty acid
dialkylamides and
dialkanolamides

Fatty acid
dialkylamides and
dialkanolamides

Formaldehyde

Formaldehyde

Hydrogen peroxide,
and other compounds
or mixtures that
release hydrogen
peroxide, including
carbamide peroxide
and zinc peroxide

Hydrogen peroxide
and other compounds
or mixtures that
release hydrogen
peroxide, including
urea peroxide and
zinc peroxide

24

27

30

( )

0.5%

(Nitrosating system)
;
5%();

50g/kg;

5%()

0.05%

(a)

(a) 12%(40 ,
H2O2 )

(a) ;
;
;
,

(b)

(b) 4%( H2O2


)

(b) ;
;
,

(c) ()

(c) 2%( H2O2


)

(c) ;
;
,

28

29

62

(3);

INCI

()

(d)

(d) 0.1%(
H2O2 )

Hydroquinone

Hydroquinone

0.02%()

;
;

Hydroquinone
methylether

None

0.02%()

;
;

Inorganic sulphites
and hydrogen
sulphites

Inorganic sulfites and


hydrogen sulfites

(a)
(b)
(c)

(d)

(a) 0.67 %( SO2 )


(b) 6.7 %( SO2 )
(c) 0.45%( SO2 )

(a)

(a)

31

32

33

Lithium hydroxide

Lithium hydroxide

(d) 0.40%( SO2 )


(a)
(4)

1.

1. 2%()

2.

2. 4.5%()(4)

1. ;
;
;

2. ;
;

34

Magnesium fluoride

Magnesium fluoride

(b) pH

(b) pH12.7

(c) , pH
(
)

(c) pH11

35

63

0.15%( F ),
, F
0.15%

(b) ;
;

INCI

Magnesium
fluorosilicate

Magnesium
fluorosilicate

Monoalkylamines,
monoalkanolamines
and their salts

Monoalkylamines,
monoalkanolamines
and their salts

Musk ketone

Musk ketone

36

()

0.15%( F ),
, F
0.15%

(Nitrosating system)
; :
99%;
0.5% ();

50g/kg;

37

38

(
)

(a) 1.4%
(b) 0.56%
(c) 0.042%

Musk xylene

None

39

(
)

(a) 1.0%
(b) 0.4%
(c) 0.03%

()

Nicomethanol
hydrofluoride

Nicomethanol
hydrofluoride

0.15%( F ),
, F
0.15%

Nitromethane

Nitromethane

0.3%

Octadecenyl-ammoni
um fluoride

Octadecenyl
ammonium fluoride

0.15%( F ),
, F
0.15%

3-(N-Hexadecyl-N-2hydroxyethylammoni
o)propylbis(2-hydrox
yethyl)ammonium
difluoride

Olaflur

0.15%( F ),
, F
0.15%

Oxalic acid, its esters


and alkaline salts

Oxalic acid, its esters


and alkaline salts

5%

40
41
42

43

44

64

Quinolin-8-ol and
bis(8-hydroxyquinoli
nium) sulphate

INCI
Oxyquinoline,
oxyquinoline sulfate

45

46

Palmityl
trihydroxyethyl
propylenediamine
dihydrofluoride

NNN-Tris
(polyoxyethylene)-Nhexadecylpropylened
iamine
dihydrofluoride

l-Phenoxy-propan-2-ol Phenoxyisopropanol

47

()
(a)
,

(a) 0.3% ()

(b)
,

(b) 0.03% ()

0.15%( F ),
, F
0.15%

(a)

2%

(b)

Polyacrylamides

Polyacrylamides

48

(a)

(a)
0.1mg/kg

(b)

(b)
0.5mg/kg

Potassium fluoride

Potassium fluoride

0.15%( F ),
, F
0.15%

Potassium
fluorosilicate

Potassium
fluorosilicate

0.15%( F ),
, F
0.15%

(
)

Potassium or sodium
hydroxide

Potassium hydroxide,
sodium hydroxide

(a) ()

(a) 5% ()(4)

(a) ;
;
;

49

50

51

65

54

INCI

Potassium
monofluorophosphate

Potassium
monofluorophosphate

Quinine and its salts

Quinine and its salts

52

53

()

(b)

(b)

(b)

1.

1. 2% ()(4)

1. ;
;
;

2.

2. 4.5% ()(4)

2. ;
;

(c) pH

(c) pH12.7

(d) , pH

(d) pH11

0.15%( F ),
, F
0.15%

(a) ()

(a) 0.5% ()

(b) ()

(b) 0.2% ()

Resorcinol

Resorcinol

0.5%

Salicylic acid

Salicylic acid

(a)

(a)2.0%

(b)

(b)3.0%

55

(c) ;

Selenium disulphide

Selenium disulfide

1%

Silver nitrate

Silver nitrate

4%

;
,

Sodium fluoride

Sodium fluoride

0.15%( F ),
, F
0.15%

56

57

58

66

INCI

Sodium fluorosilicate

Sodium fluorosilicate

0.15%( F ),
, F
0.15%

Sodium
monofluorophosphate

Sodium
monofluorophosphate

0.15%( F ),
, F
0.15%

Sodium nitrite

Sodium nitrite

0.2%

Stannous fluoride

Stannous fluoride

0.15%( F ),
, F
0.15%

(5)

Strontium acetate
hemihydrate

Strontium acetate
hemihydrate

3.5%(),
,
3.5%

(5)

Strontium chloride
hexahydrate

Strontium chloride
hexahydrate

(a)

(a) 3.5%(),
,
3.5%

(b)

(b) 2.1%(),
,
2.1%

()

59

60

61

62

63

64

65

()

(5)

Strontium hydroxide

Strontium hydroxide

pH

3.5%()

pH12.7

(5)

Strontium peroxide

Strontium peroxide

4.5%(
)

;
,
;
;

Talc: hydrated
magnesium silicate

Talc: hydrated
magnesium silicate

(a) 3

66

67

(b)

67

(a)

INCI

()

(1)

(1) Thioglycollic acid


and its salts

(1) Thioglycolic acid


and its salts

(a)

(a)

1.

1. 8%, pH7-9.5

2.

2. 11%, pH7-9.5

(b)

(b) 5%, pH7-12.7

(a) :
;
,
,
;
(b) :
;
,
,

(c)

68

(2)

(2) Thioglycollic acid


esters

(2) Thioglycolic acid


esters

(c) 2%, pH7-9.5

(c) :

;
,
,
;

1.

1. 8%, pH6-9.5

2.

2. 11%, pH6-9.5

Trialkylamines,
trialkanolamines and
their salts

Trialkylamines,
trialkanolamines and
their salts

Triclocarban (INN)

Triclocarban

(a)

(a) 2.5%

(Nitrosating system)
; :
99%;
0.5% ();

50g/kg;

1.5%

: 3,3,4,4-
1mg/kg;

(b)

69

70

68


;
;
,
, ;

(a) ;
;
;

(b) ;
;

(c) ;
;

;
;
;

INCI

()

3,3,4,4-
1mg/kg

71

Water-soluble zinc
salts with the
exception of zinc
4-hydroxybenzenesul
phonate and zinc
pyrithione

Water-soluble zinc
salts with the
exception of zinc
phenolsulphonate and
zinc pyrithione

Zinc
4-hydroxybenzene
sulphonate

Zinc phenolsulfonate

6% ()

Pyrithione zinc (INN)

Zinc pyrithione

1.5%

72
73

1% ()

(1) - -,
;

(2) 4
(3) 0.05%,
(4) NaOH, LiOH KOH NaOH ,
(5)

69

(1)

( INCI )

INCI

2--2--1,3

Bronopol (INN)

2-Bromo-2-nitropropane-1,3-di
ol

0.1%

5--5--1,3-

5-Bromo-5-nitro-1,3-dioxane

5-Bromo-5-nitro-1,3-dioxane

0.1%

7-

5-Ethyl-3,7-dioxa-1-azabicyclo[3.
3.0]octane

7-Ethylbicyclooxazolidine

0.3%

(C12-C22)
2

Alkyl(C12-C22) trimethyl
ammonium, bromide and chloride

Alkyl(C12-C22) trimonium
bromide and chloride

0.1%

, ,
2

Benzalkonium chloride, bromide


and saccharinate

Benzalkonium chloride,
bromide and saccharinate

0.1%()

Benzethonium chloride

Benzethonium chloride

0.1%

1
2
3

(1)
(2)

Benzoic acid, its salts and esters

Benzoic acid, its salts and esters

0.5%()

Benzyl alcohol

Benzyl alcohol

1.0%

Benzylhemiformal

Benzylhemiformal

0.15%

10

6,6-Dibromo-4,4-dichloro-2,2-met
hylene-diphenol

Bromochlorophen

0.1%

Chlorhexidine (INN) and its


digluconate,diacetate and
dihydrochloride

Chlorhexidine and its


digluconate, diacetate and
dihydrochloride

0.3%()

11
12

2-Chloroacetamide

Chloroacetamide

0.3%

13

Chlorobutanol (INN)

Chlorobutanol

0.5%

14

2-Benzyl-4-chlorophenol

Chlorophene

0.2%

15

4-Chloro-3,5-xylenol

Chloroxylenol

0.5%

3-(p-chlorophenoxy)-propane-1,2diol

Chlorphenesin

0.3%

16

70

INCI

17

1-(4-chlorophenoxy)-1-(imidazol1-yl)-3,3-dimethylbutan-2-one

Climbazole

0.5%

18

3-Acetyl-6-methylpyran-2,4
(3H)-dione and its salts

Dehydroacetic acid

0.6%()

()

N-(Hydroxymethyl)-N-(dihydroxy
methyl-1,3-dioxo-2,5-imidazolinid
yl-4)-N-(hydroxymethyl) urea

Diazolidinyl urea

0.5%

3,3-Dibromo-4,4-hexamethylene
dioxydibenzamidine and its salts
(including isethionate)

Dibromohexamidine and its


salts, including
dibromohexamidine isethionate

0.1%

20
21

2,4-Dichlorobenzyl alcohol

Dichlorobenzyl alcohol

0.15%

22

4,4-Dimethyl-1,3-oxazolidine

Dimethyl oxazolidine

0.1%

23

DMDM

1,3-Bis(hydroxymethyl)-5,5-dimeth DMDM hydantoin


ylimidazolidine-2,4-dione

0.6%

Formaldehyde and
paraformaldehyde

0.2%()

19

24

Formaldehyde and
paraformaldehyde

pH 6

0.1%()
()

Formic acid and its sodium salt

Formic acid and its sodium salt

0.5%()

Glutaraldehyde (Pentane-1,5-dial)

Glutaral

0.1%

1,6-Di(4-amidinophenoxy)-n-hexa
ne and its salts (including
isethionate and
p-hydroxybenzoate)

Hexamidine and its salts,


including hexamidine
diisethionate and hexamidine
paraben

0.1%

27

28

Hexetidine (INN)

Hexetidine

0.1%

3,3-Bis(1-hydroxymethyl-2,5-dio
xoimidazolidin-4-yl)-1,1-methyle
nediurea

Imidazolidinyl urea

0.6%

Inorganic sulphites and


hydrogensulphites

Inorganic sulfites and hydrogen


sulfites

0.2%( SO2 )

25
26

29
30

71

0.05%)

INCI

3-Iodo-2-propynylbutylcarbamate

Iodopropynyl butylcarbamate

0.05%

32

Hexamethylenetetramine (INN)

Methenamine

0.15%

33

1,2-Dibromo-2,4-dicyanobutane

Methyldibromo glutaronitrile

0.1%

34

2-Methylisothiazol-3(2H)-one

Methylisothiazolinone

0.01%

35

Mixture of
5-chloro-2-methylisothiazol-3(2H)
-one and
2-methylisothiazol-3(2H)-one with
magnesium chloride and
magnesium nitrate

Mixture of
methylchloroisothiazolinone
and methylisothiazolinone with
magnesium chloride and
magnesium nitrate

0.0015%(

3: 1 )

36

o--5-

4-Isopropyl-m-cresol

o-Cymen-5-ol

0.1%

37

o-

Biphenyl-2-ol and its salts

o-Phenylphenol

0.2%()

38

4-

4-Hydroxybenzoic acid and its


salts and esters

4-Hydroxybenzoic acid and its


salts and esters

: 0.4%()

39

p--m-

4-Chloro-m-cresol

p-Chloro-m-cresol

0.2%

40

2-Phenoxyethanol

Phenoxyethanol

1.0%

1-Phenoxypropan-2-ol

Phenoxyisopropanol

1.0%

1-Hydroxy-4-methyl-6(2,4,4-trime
thylpentyl)2-pyridon and its
monoethanolamine salt

Piroctone olamine

(a) 1.0%
(b) 0.5%

(a)

31

41

42

Poly(1-hexamethylenebiguanide)
hydrochloride

Polyaminopropyl biguanide
hydrochloride

0.3%

44

Propionic acid and its salts

Propionic acid and its salts

2%()

45

-15

Methenamine
3-chloroallylochloride (INNM)

Quaternium-15

0.2%

Salicylic acid and its salts

Salicylic acid and its salts

0.5%()

46

72

,
0.02%,
:

: 0.8%()

43

(b)

(3)

INCI

Phenylmercuric salts (including


borate)

Salts of phenylmercury,
including borate

0.007%( Hg ),

, Hg
0.007%

Silver chloride deposited on


titanium dioxide

Silver chloride deposited on


titanium dioxide

0.004%( AgCl )

TiO2
20%((w/w)) AgCl,

49

Sodium hydroxymethylamino
acetate

Sodium hydroxymethylglycinate 0.5%

50

Sodium iodate

Sodium iodate

0.1%

51

Sorbic acid (hexa-2,4-dienoic acid)


and its salts

Sorbic acid and its salts

0.6%()

Thiomersal (INN)

Thimerosal

0.007%( Hg ),

, Hg
0.007%

Triclocarban (INN)

Triclocarban

0.2%

: 3,3,4,4-
1mg/kg;
3,3,4,4-
1mg/kg

54

Triclosan (INN)

Triclosan

0.3%

55

Undec-10-enoic acid and salts

Undecylenic acid and salts

0.2%()

Pyrithione zinc (INN)

Zinc pyrithione

0.5%

47

48

52

53

56

(1) a
b , (essential oil),
c ;

73

d , 0.05%(),
(2) , 3
(3) , ,

74

5 (1)
( INCI )

INCI

3-

3-Benzylidene camphor

3-Benzylidene camphor

2%

4-

3-(4-Methylbenzylidene)-d-l camphor

4-Methylbenzylidene camphor

4%

-3

Oxybenzone (INN)

Benzophenone-3

10%

-4

2-Hydroxy-4-methoxybenzophenone-5-sulfonic
acid and its sodium salt

Benzophenone-4
Benzophenone-5

5%()

4
5

-5

Alpha-(2-oxoborn-3-ylidene)-toluene-4-sulphoni Benzylidene camphor sulfonic acid


c acid and its salts

6%()

- (1,3,5)-Triazine-2,4-bis((4-(2-ethyl-hexyloxy)-2- Bis-ethylhexyloxyphenol
hydroxy)-phenyl)-6-(4-methoxyphenyl)
methoxyphenyl triazine

10%

1-(4-Tert-butylphenyl)-3-(4-methoxyphenyl)
propane-1,3-dione

Butyl methoxydibenzoylmethane

5%

Camphor
methosulfate

N,N,N-trimethyl-4-(2-oxoborn-3-ylidenemethyl)
anilinium methyl sulphate

benzalkonium 6%

Benzoic acid, 2-(4-(diethylamino)


-2-hydyoxybenzoyl) -,hexyl ester

Diethylamino
hexyl benzoate

hydyoxybenzoyl 10%

Benzoic acid, 4,4-((6-(((((1,1-dimethylethyl)


amino) carbonyl)phenyl)amino) 1,3,5-triazine2,4-diyl)diimino)bis-, bis-(2-ethylhexyl) ester

Diethylhexyl butamido triazone

10
11

2,2--(1,4-)1H- Disodium salt of 2,2-bis-(1,4-phenylene)1Hbenzimidazole-4,6-disulphonic acid


-4,6-)

Disodium phenyl dibenzimidazole 10%()


tetrasulfonate

10%

Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6Drometrizole trisiloxane


(2-methyl-3-(1,3,3,3-tetramethyl-1-(trimethylsily
l)oxy)-disiloxanyl)propyl

15%

13

PABA

4-Dimethyl amino benzoate of ethyl-2-hexyl

Ethylhexyl dimethyl PABA

8%

14

2-Ethylhexyl 4-methoxycinnamate

Ethylhexyl methoxycinnamate

10%

15

2-Ethylhexyl salicylate

Ethylhexyl salicylate

5%

12

75

-3(2)

16

2,4,6-Trianilino-(p-carbo-2-ethylhexyl-l-oxy)1,3,5-triazine

Ethylhexyl triazone

5%

17

Homosalate (INN)

Homosalate

10%

18

p-

Isopentyl-4-methoxycinnamate

Isoamyl p-methoxycinnamate

10%

19

- 2,2-Methylene-bis-6-(2H-benzotriazol-2yl)-4-(t
etramethyl-butyl)-1,1,3,3-phenol

Methylene
bis-benzotriazolyl 10%
tetramethylbutylphenol

20

2-Cyano-3,3-diphenyl acrylic acid, 2-ethylhexyl


ester

Octocrylene

10%()

21

4-Aminobenzoic acid

PABA

5%

22

PEG-25

Ethoxylated ethyl-4-aminobenzoate

PEG-25 PABA

10%

23

2-Phenylbenzimidazole-5-sulphonic acid and its


potassium, sodium, and triethanolamine salts

Phenylbenzimidazole sulfonic acid 8%()


and its potassium, sodium, and
triethanolamine salts

24

Polymer of N-{(2 and 4)-[(2-oxoborn-3-ylidene)


methyl]benzyl} acrylamide

Polyacrylamidomethyl benzylidene 6%
camphor

25

-15

Dimethicodiethylbenzalmalonate

3,3-(1,4-Phenylenedimethylene)bis(7,7-dimethy Terephthalylidene
dicamphor 10%()
l-2-oxobicyclo-[2.2.1]hept-1-yl-methanesulphoni sulfonic acid and its salts
c acid) and its salts

(3)

Titantum dioxide

Titantum dioxide

25%

Zinc oxide

Zinc oxide

25%

26
27
28

(3)

Polysilicone-15

10%

(1) , ,
,
(2) 0.5%, ,
(3) , 6

76

(1)

(Color Index)

(C.I. generic name)

CI 10006

PIGMENT GREEN 8

CI 10020

ACID GREEN 1

CI 10316 (2)

ACID YELLOW 1

CI 11680

FOOD YELLOW 1

CI 11710

PIGMENT YELLOW 3

CI 11725

PIGMENT ORANGE 1

CI 11920

FOOD ORANGE 3

CI 12010

SOLVENT RED 3

1- (1-Naphthol) 0.2%; 2,4- -1-


(2,4-Dinitro-1-naphthol) 0.03%

3%; 2- -4-
(2-Chloro-4-nitrobenzenamine) 0.3%; 2-
(2-Naphthalenol) 1%; 2,4-
(2,4-Dinitrobenzenamine) 0.02%; 1-[(2,4-
) ]-2- (1-[(2,4-Dinitrophenyl)azo]2-naphthalenol) 0.5%; 4-[(2--4-)]-1 (4-[(2-Chloro-4-nitrophenyl)azo]-1-naphthalenol)
0.5%; 1-[(4- ) ]-2- (1-[(4Nitrophenyl)azo]-2-naphthalenol) 0.3%; 1-[(4--2 ) ]-2- (1-[(4-Chloro-2-nitrophenyl)
azo]-2-naphthalenol) 0.3%

CI 12085 (2)

PIGMENT RED 4

10

CI 12120

PIGMENT RED 3

11

CI 12370

PIGMENT RED 112

112

12

CI 12420

PIGMENT RED 7

13

CI 12480

PIGMENT BROWN 1

77

4--(4-Chloro-o-toluidine)
: 5mg/kg

(Color Index)

(C.I. generic name)

14

CI 12490

PIGMENT RED 5

15

CI 12700

DISPERSE
16

16

16

CI 13015

FOOD YELLOW 2

17

CI 14270

ACID ORANGE 6

YELLOW

18

CI 14700

FOOD RED 1

5- -2,4- -1-
(5-Amino-2,4-dimethyl-1-benzenesulfonic acid and its
sodium salt) 0.2%; 4- -1-
(4-Hydroxy-1-naphthalenesulfonic acid and its sodium salt)
0.2%

19

CI 14720

FOOD RED 3

4--1-(4-Aminonaphthalene-1-sulfonic acid) 4-1-(4-Hydroxynaphthalene-1-sulfonic acid)


0.5%; 0.01%()

20

CI 14815

FOOD RED 2

21

CI 15510 (2)

ACID ORANGE 7

22

CI 15525

PIGMENT RED 68

68

23

CI 15580

PIGMENT RED 51

51

24

CI 15620

ACID RED 88

88

PIGMENT RED 49

49

PIGMENT RED 64

64

25

CI 15630

26

CI 15800

27

(2)

CI 15850 (2)

PIGMENT RED 57

57

2-(2-Naphthol) 0.4%; (Sulfanilic acid,


sodium salt) 0.2%; 4,4-()-
(4,4-(Diazoamino)-dibenzenesulfonic acid) 0.1%

3%

(Aniline) 0.2%; 3- -2-


(3-Hydroxy-2-naphthoic acid, calcium salt) 0.4%
2- -5- (2-Amino-5methylbenzensulfonic acid, calcium salt) 0.2%; 3-
-2-(3-Hydroxy-2-naphthalene carboxylic
acid, calcium salt) 0.4%;
0.01%()

78

(Color Index)

(C.I. generic name)

28

CI 15865 (2)

PIGMENT RED 48

48

29

CI 15880

PIGMENT RED 63

63

30

CI 15980

FOOD ORANGE 2

31

32

CI 15985 (2)

CI 16035

FOOD YELLOW 3

FOOD RED 17

17

33

CI 16185

FOOD RED 9

34

CI 16230

ACID ORANGE 10

10

2--1-(2-Amino-1- naphthalenesulfonic acid,


calcium salt) 0.2%; 3--2-(3-Hydroxy-2naphthoic acid) 0.4%

4--1-(4-Aminobenzene-1-sulfonic acid)3-
-2,7-(3-Hydroxynaphthalene- 2,7-disulfonic acid)
6--2-(6-Hydroxynaphthalene-2-sulfonic acid)
7- -1,3- (7-Hydroxynaphthalene
-1,3-disulfonic acid) 4,4-
(4,4-diazoaminodi(benezene sulfonic acid))
0.5%; 6,6- (2- )
(6,6-Oxydi(2-naphthalene sulfonic acid) disodium salt)
1.0%; 0.01 %()

6--2-(6-Hydroxy-2-naphthalene sulfonic acid,


sodium salt ) 0.3%; 4--5--2-
(4-Amino-5-methoxy-2-methylbenezene sulfonic acid)
0.2%; 6,6- (2- )
(6,6-Oxydi(2-naphthalene sulfonic acid)disodium salt)
1.0%; 0.01%()

4--1-(4-Aminonaphthalene-1-sulfonic acid)3 -2,7- (3-Hydroxynaphthalene-2,7-disulfonic


acid)6--2-(6-Hydroxynaphthalene-2-sulfonic
acid) 7- -1,3- (7Hydroxynaphthalene-1,3-disulfonic acid) 7--1,3,6(7-Hydroxy naphthalene-1,3,6- trisulfonic acid)
0.5%; 0.01%()

79

(Color Index)

(C.I. generic name)

35

CI 16255 (2)

FOOD RED 7

36

CI 16290

FOOD RED 8

37

CI 17200 (2)

FOOD RED 12

12

4--1-(4-Aminonaphthalene-1-sulfonic acid)3-2,7-(3- Hydroxynaphthalene-2,7-disulfonic


acid)6--2-(6-Hydroxynaphthalene-2-sulfonic
acid) 7- -1,3- (7-Hydroxynaphthalene
-1,3-disulfonic acid) 7--1,3,6-(7-Hydroxy
naphthalene-1,3,6- trisulfonic acid) 0.5%;
0.01%()
4- -5- -2,7- (4-Amino-5-hydroxy2,7-naphthalenedisulfonic acid, disodium salt) 0.3%;
4,5- -3-( )-2,7-
(4,5-Dihydroxy-3-(phenylazo)-2,7-naphthalenedisulfonic
acid, disodium salt) 3%; (Aniline)
25mg/kg; 4- (4-Aminoazobenzene)
100g/kg; 1,3-(1,3- Diphenyltriazene)
125g/kg; 4-(4-Aminobiphenyl) 275g/kg;
(Azobenzene) 1mg/kg; (Benzidine)
20g/kg

5- -4- -2,7-
(5-Acetamido-4-hydroxynaphthalene-2,7-disulfonic acid)
5- -4-- -2,7-
(5-Amino-4-hydroxynaphthalene-2,7-disulfonic acid)
0.5%; 0.01%()

38

CI 18050

FOOD RED 10

10

39

CI 18130

ACID RED 155

155

40

CI 18690

ACID YELLOW 121

121

41

CI 18736

ACID RED 180

180

42

CI 18820

ACID YELLOW 11

11

43

CI 18965

FOOD YELLOW 5

80

(Color Index)

(C.I. generic name)

4-(4-Hydrazinobenzene sulfonic acid)4-


-1-(4-Aminobenzene-1-sulfonic acid)5--1-(4-
)-2- -3- (5-Oxo-1-(4-sulfophenyl)2-pyrazoline-3-carboxylic acid)4,4-
(4,4-Diazoaminodi(benzene sulfonic acid))
(Tetrahydroxy succinic acid) 0.5%;
0.01%()

44

CI 19140 (2)

FOOD YELLOW 4

45

CI 20040

PIGMENT
16

16

46

CI 20470

ACID BLACK 1

47

CI 21100

PIGMENT
13

YELLOW

13

3,3-(3,3- dimethylbenzidine)
: 5mg/kg

48

CI 21108

PIGMENT
83

YELLOW

83

3,3-(3,3- dimethylbenzidine)
: 5mg/kg

49

CI 21230

SOLVENT
29

YELLOW

29

50

CI 24790

ACID RED 163

163

51

CI 27755

FOOD BLACK 2

YELLOW

3,3-(3,3- dimethylbenzidine)
: 5mg/kg

52

CI 28440

FOOD BLACK 1

53

CI 40215

DIRECT ORANGE 39

39

54

CI 40800

FOOD ORANGE 5

55

CI 40820

FOOD ORANGE 6

4--5--1,7-(4-Acetamido-5-hydroxy
naphthalene-1,7-disulfonic acid)4--5--1,7-
(4-Amino-5- hydroxy naphthalene-1,7-disulfonic acid)8 -2- (8-Aminonaphthalene-2-sulfonic acid)
4,4- (4,4-diazoaminodi(benzenesulfonic acid)) 0.8%;
0.01%()

81

(Color Index)

(C.I. generic name)

56

CI 40825

FOOD ORANGE 7

57

CI 40850

FOOD ORANGE 8

58

CI 42045

ACID BLUE 1

59

CI 42051 (2)

FOOD BLUE 5

60

CI 42053

FOOD GREEN 3

61

CI 42080

ACID BLUE 7

3-(3-Hydroxy benzaldehyde)3-
(3-Hydroxy benzoic acid) 3-
(3-Hydroxy-4-sulfobenzoic acid) N,N-
(N,N-diethylamino benzenesulfonic acid) 0.5%;
(Leuco base) 4.0%;
0.01%()

(Leuco base) 5%; 2-,3-,4-


(2-,3-,4-Formylbenzenesulfonic acids and their
sodium salts) 0.5%; 3- 4-[(4-)
](3- and 4-[(Ethyl(4-sulfophenyl)
amino)methyl]benzenesulfonic acid and its disodium salts)
0.3%; 2- -5-
(2-Formyl-5- hydroxybenzenesulfonic acid and its sodium
salt) 0.5%

2-,3- 4-(2-,3- and 4-Formyl benzene


sulfonic acids) 1.5%; 3-((4-))
(3-(Ethyl(4-sulfophenyl)amino)methyl benzene
sulfonic acid) 0.3%; (Leuco base)
5.0%; 0.01%()

62

CI 42090

FOOD BLUE 2

63

CI 42100

ACID GREEN 9

64

CI 42170

ACID GREEN 22

22

65

CI 42510

BASIC VIOLET 14

14

66

CI 42520

BASIC VIOLET 2

67

CI 42735

ACID BLUE 104

104

82

5mg/kg

68

(Color Index)

CI 44045

(C.I. generic name)

BASIC BLUE 26

26

4,4- ( ) (4,4-Bis(dimethylamino)
benzhydryl alcohol) 0.1%; 4,4-()
(4,4-Bis(dimethylamino) benzophenone) 0.1%; 3-
-2,7- (3-Hydroxynaphthalene-2,7- disulfonic
acid) 0.2%; (Leuco base) 5.0%;
0.01%()

69

CI 44090

FOOD GREEN 4

70

CI 45100

ACID RED 52

52

71

CI 45190

ACID VIOLET 9

72

CI 45220

ACID RED 50

50

73

CI 45350

ACID YELLOW 73

74

CI 45370 (2)

75

CI 45380

(2)

76

CI 45396

ACID ORANGE 11

73

11

6%; (Resorcinol)
0.5%; (Phthalic acid) 1%; 2-(2,4-
)(2-(2,4-Dihydroxybenzoyl) benzoic acid)
0.5%

2-(6- -3- -3H- -9- ) (2-(6-Hydroxy3-oxo-3H-xanthen-9-yl)benzoic acid) 1%; 2-(-6-


-3- -3H- -9- ) (2-(Bromo-6hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid) 2%

ACID RED 87

87

2-(6- -3- -3H- -9- ) (2-(6-Hydroxy-3oxo-3H-xanthen-9-yl)benzoic acid) 1%; 2-(-6-


-3- -3H- -9- ) (2-(Bromo-6hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid) 2%

SOLVENT
16

16

, (),
1%

ORANGE

77

CI 45405

ACID RED 98

98

78

CI 45410 (2)

ACID RED 92

92

2-(6- -3- -3H- -9- ) (2-(6-Hydroxy-3oxo-3H-xanthen-9-yl)benzoic acid) 1%; 2-(-6-


-3- -3H- -9- ) (2-(Bromo-6hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid) 2%
2-(6- -3- -3H- -9- )

83

(Color Index)

(C.I. generic name)

(2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid)
1%; 2-(-6--3--3H--9-)(2-(Bromo-6hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid) 2%
79

CI 45425

ACID RED 95

95

(Triiodoresorcinol) 0.2%; 2-(2,4-


-3,5- ) (2-(2,4-dihydroxy-3,5
-dioxobenzoyl) benzoic acid) 0.2%

80

CI 45430 (2)

FOOD RED 14

14

(Triiodoresorcinol) 0.2%; 2-(2,4-


-3,5- ) (2-(2,4-dihydroxy3,5-dioxobenzoyl) benzoic acid) 0.2%

81

CI 47000

SOLVENT
33

33

YELLOW

82

CI 47005

FOOD YELLOW 13

13

83

CI 50325

ACID VIOLET 50

50

84

CI 50420

ACID BLACK 2

85

CI 51319

PIGMENT VIOLET 23

23

86

CI 58000

PIGMENT RED 83

83

87

CI 59040

SOLVENT GREEN 7

88

CI 60724

DISPERSE VIOLET 27

27

89

CI 60725

SOLVENT VIOLET 13

13

(Phthalic acid) 0.3%; 2-


(Quinaldine) 0.2%

2- (2-methylquinoline) 2-
(2-methylquinoline sulfonic acid) (Phthalic
acid)2,6-(2,6-dimethyl quinoline) 2,6-
(2,6-dimethyl quinoline sulfonic acid)
0.5%; 2-(2- )2,3- -1,3-
(2-(2-quinolyl)indan -1,3-dione) 4mg/kg;
0.01%()

1,3,6- (Trisodium salt of 1,3,6-pyrene


trisulfonic acid) 6%; 1,3,6,8-
(Tetrasodium salt of 1,3,6,8-pyrene tetrasulfonic acid)
1%; (Pyrene) 0.2%

-(p-Toluidine) 0.2%; 1--9,10-


(1-Hydroxy-9,10- anthracenedione) 0.5%; 1,4-

84

(Color Index)

(C.I. generic name)

-9,10-(1,4-Dihydroxy-9,10-anthracenedione)
0.5%

90

CI 60730

ACID VIOLET 43

43

1--9,10-(1-Hydroxy-9,10- anthracenedione)
0.2%; 1,4--9,10-(1,4-Dihydroxy-9,10anthracenedione) 0.2%; (p-Toluidine)
0.1%; (p-Toluidine sulfonic acids,
sodium salts) 0.2%

91

CI 61565

SOLVENT GREEN 3

- (p-Toluidine) 0.1%; 1,4-


(1,4-Dihydroxyanthraquinone) 0.2%; 1--4-[(4 ) ]-9,10- (1-Hydroxy-4-[(4-methyl
phenyl)amino]-9,10-anthracenedione) 5%

92

CI 61570

ACID GREEN 25

25

1,4- (1,4-Dihydroxy anthraquinone)


0.2%; 2---(2-Amino-m-toluene sulfonic
acid) 0.2%

93

CI 61585

ACID BLUE 80

80

94

CI 62045

ACID BLUE 62

62

95

CI 69800

FOOD BLUE 4

96

CI 69825

VAT BLUE 6

97

CI 71105

VAT ORANGE 7

98

CI 73000

VAT BLUE 1

99

CI 73015

FOOD BLUE 1

100

CI 73360

VAT RED 1

101

CI 73385

VAT VIOLET 2

102

CI 73900

PIGMENT VIOLET 19

19

-5-(Isatin-5-sulfonic acid)5-
(5-Sulfoanthranilic acid)(Anthranilic acid)
0.5%; 0.01%(
)

85

(Color Index)

(C.I. generic name)

103

CI 73915

PIGMENT RED 122

122

104

CI 74100

PIGMENT BLUE 16

16

105

CI 74160

PIGMENT BLUE 15

15

106

CI 74180

DIRECT BLUE 86

86

107

CI 74260

PIGMENT GREEN 7

108

CI 75100

NATURAL YELLOW 6

109

CI 75120

NATURAL ORANGE 4

110

CI 75125

27

111

CI 75130

26

112

CI 75135

RUBIXANTHIN

113

CI 75170

NATURAL WHITE 1

114

CI 75300

NATURAL YELLOW 3

115

CI 75470

NATURAL RED 4

116

CI 75810

NATURAL GREEN 3

NATURAL
27
NATURAL
26

YELLOW
YELLOW

117

CI 77000

PIGMENT METAL 1

1
(, Al)

118

CI 77002

PIGMENT WHITE 24

24

119

CI 77004

PIGMENT WHITE 19

19

120

CI 77007

PIGMENT BLUE 29

29

121

CI 77015

PIGMENT RED 101,


102

101, 102
(
)

122

CI 77019

PIGMENT WHITE 20

20()

86

(Color Index)

(C.I. generic name)

123

CI 77120

PIGMENT WHITE 21,


22

21, 22
(, BaSO4)

124

CI 77163

PIGMENT WHITE 14

14 (
, BiOCl)

125

CI 77220

PIGMENT WHITE 18

18
(, CaCO3)

126

CI 77231

PIGMENT WHITE 25

25
(, CaSO4)

: 1g 10g ,
,
(quinine sulfate)(0.1g
1000mL 0.01mol/L )

127

CI 77266

PIGMENT BLACK 6,7

6, 7

128

CI 77267

PIGMENT BLACK 9

129

CI 77268:1

FOOD BLACK 3

130

CI 77288

PIGMENT GREEN 17

17 (
, Cr2O3)

(Chromate)

131

CI 77289

PIGMENT GREEN 18

18
(Cr2O(OH)4)

(Chromate)

132

CI 77346

PIGMENT BLUE 28

28

133

CI 77400

PIGMENT METAL 2

2
(, Cu)

134

CI 77480

PIGMENT METAL 3

3
(, Au)

135

CI 77489

FERROUS OXIDE

, FeO

136

CI 77491

PIGMENT RED 101,


102

101, 102
(, Fe2O3)

137

CI 77492

PIGMRNT
42, 43

42, 43
(FeO(OH).nH2O)

YELLOW

87

(Color Index)

(C.I. generic name)

138

CI 77499

PIGMENT BLACK 11

11
(FeO+Fe2O3)

139

CI 77510

PIGMENT BLUE 27


27
(Fe4(Fe(CN)6)3+F
eNH4Fe(CN)6)

140

CI 77713

PIGMENT WHITE 18

18
(, MnCO3)

141

CI 77718

PIGMENT WHITE 26

26()

142

CI 77742

PIGMENT VIOLET 16

16
((NH4)2MnP2O7)

143

CI 77745

MANGANESE
PHOSPHATE

,
Mn3(PO4)2.7H2O

144

CI 77820

SILVER

, Ag

145

CI 77891(3)

PIGMENT WHITE 6

6
(, TiO2)

146

CI 77947(3)

PIGMENT WHITE 4

4
(, ZnO)

147

ACID RED 195

195

148

ALUMINUM, ZINC,
MAGNESINM
AND
CALCIUM STEARATE

149

ANTHOCYANINS

BEET ROOT RED

150
151
152
153

BROMOCRESOL
GREEN
BROMOTHYMOL
BLUE
CAPSANTHIN,
CAPSORUBIN

88

(Color Index)

(C.I. generic name)

154

CARAMEL

155

LACTOFLAVIN

156

SORGHUM RED

(1) a 2
b , 15850:1, 15850:2, ,
(2) ,
(3) , 5

89

(1)
( INCI )

INCI

1,3-Bis-(2,4-diaminophenoxy) propane
HCl
1,3-Bis-(2,4-diaminophenoxy) propane

2.0()

, 1.0%

1,3--(2,4-)
HCl
1,3--(2,4-)

2.0

, 1.0%

1,5-(CI76625)

1,5-Naphthalenediol

1.0

, 0.5%

1- 4,5-

1-(CI76605)

1-Hydroxyethyl
sulfate

2.25

, 1.125%

1-Naphthol

2.0

, 1.0%

2,4-Diaminophenol

10.0

2,4-Diaminophenol HCl

10.0()

5
6

2,4-

4,5-diaminopyrazole

2,4- HCl

2,4-HCl

2,4-Diaminophenoxyethanol HCl

4.0()

, 2.0%

2,4-

2,4-Diaminophenoxyethanol sulfate

4.0()

, 2.0%

10

2,6-

2,6-Diaminopyridine

0.004

, 0.002%

11

2,6-

2,6-Diaminopyridine sulfate

12

2,6-

2,6-Dihydroxyethylaminotoluene

2.0

, 1.0%

13

2,6--3,5- HCl

0.5

, 0.25%

14

2,7-(CI76645)

2,6-Dimethoxy-3,5-pyridinediamine
HCl
2,7-Naphthalenediol

1.0

, 0.5%

15

2--3-

2-Amino-3-hydroxypyridine

0.6

, 0.3%

16

2--4-

2-Amino-4-hydroxyethylaminoanisole

3.0

, 1.5%

17

2--4-

2-Amino-4-hydroxyethylaminoanisole
sulfate

3.0()

, 1.5%

18

2--6--4-

2-Amino-6-chloro-4-nitrophenol

2.0

, 1.0%

19

2--6--4-HCl

2-Amino-6-chloro-4-nitrophenol HCL

2.0()

, 1.0%

20

2--p-

2-Chloro-p-phenylenediamine

0.1

, 0.05%

21

2--p-

2-Chloro-p-phenylenediamine sulfate

1.0

, 0.5%

0.004() , 0.002%

90

1-

INCI

22

2-

2-Hydroxyethyl picramic acid

23

2--5-

24

, 1.5%

2-Methyl-5-hydroxyethylaminophenol

(a) 3.0
(b) 2.0(3)
2.0

2-

2-Methylresorcinol

2.0

, 1.0%

25

2--p-

2-Nitro-p-phenylenediamine

0.3

, 0.15%

26

2--p- 2HCl

0.3()

, 0.15%

27

2--p-

2-Nitro-p-phenylenediamine
dihydrochloride
2-Nitro-p-phenylenediamine sulfate

0.3()

, 0.15%

28

3--p-

3-Nitro-p-hydroxyethylaminophenol

6.0

, 3.0%

4,4-Diaminodiphenylamine

6.0

4,4-Diaminodiphenylamine sulfate

6.0()

29

4,4-

(2)
(2)

, 1.0%

30

4,4-

31

4--2-

4-Amino-2-hydroxytoluene

3.0

, 1.5%

32

4--3-

4-Amino-3-nitrophenol

3.0

, 1.5%

33

4--m-

4-Amino-m-cresol

3.0

, 1.5%

34

4-

4-Chlororesorcinol

1.0

, 0.5%

35

4--3-

4-Hydroxypropylamino-3-nitrophenol

, 2.6%

36

4--o-

4-Nitro-o-phenylenediamine

(a) 5.2
(b) 2.6(3)
1.0

, 0.5%

37

4--o-

4-Nitro-o-phenylenediamine sulfate

1.0()

, 0.5%

38

5--4--o-

5-Amino-4-chloro-o-cresol

2.0

, 1.0%

39

5--6--o-

5-Amino-6-chloro-o-cresol

2.0

, 1.0%

40

6--m-

6-Amino-m-cresol

2.4

, 1.2%

41

6--o-

6-Amino-o-cresol

3.0

, 1.5%

42

6-

6-Hydroxyindole

1.0

, 0.5%

43

6--2--3-
HCl (HC 7 )
3(CI10385)

6-Methoxy-2-methylamino-3-aminopyri
dine HCl

2.0

, 1.0%

Acid Orange 3

0.2

44

91

2-

INCI

45

43(CI60730)

Acid Violet 43

1.0

46

26(CI44045)

Basic Blue 26

0.5

<80%,
: (135)(
)18%, 0.4%, 1-
-9,10- (1-hydroxy-9,10-anthracenedione)
0.2%, p-(p-toluidine)0.1%, p-
(p-tolluidine sulfonic acids, sodium salts)0.2%,
(subsidiary colors) 1%,
20mg/kg, 3mg/kg, 1mg/kg
, 0.25%

47

31

Basic orange 31

0.2

, 0.1%

48

51

Basic red 51

0.2

, 0.1%

49

76 (CI12245)

Basic red 76

2.0

50

14(CI42510)

Basic Violet 14

0.3

, 0.15%

51

87

Basic yellow 87

0.2

, 0.1%

52

Disperse Black 9

0.4

53

Disperse Violet 1

1.0

, 0.5%

54

4(CI61105)

Disperse violet 4

0.08

, 0.04%

55

HC1

HC Orange No.1

3.0

56

HC1

HC Red No.1

0.5

57

HC3

HC Red No.3

0.5

0.5%,

58

HC2

HC Yellow No.2

3.0

, 1.5%

59

HC 4

HC Yellow No.4

3.0

60

HC 6

HC Yellow No.6

, 1.0%

61

(4)

Hydroquinone

(a) 2.0
(b) 1.0(3)
0.3

62

Hydroxybenzomorpholine

2.0

, 1.0%

63

-2--p-

Hydroxyethyl-2-nitro-p-toluidine

(a) 2.0
(b) 1.0(3)

, 1.0%

92

INCI

, 1.5%

(N- -p-
)HCl

Hydroxyethyl-3,4-methylenedioxyaniline 3.0
HCl
Hydroxyethyl-p-phenylenediamine
3.0
sulfate
Hydroxypropyl bis(N-hydroxyethyl-p- 3.0
phenylenediamine) HCl

67

m-

m-Aminophenol

2.0

, 1.0%

68

m-HCl

m-Aminophenol HCl

2.0()

, 1.0%

69

m-

m-Aminophenol sulfate

2.0()

, 1.0%

70

N,N-(2-)-p-

2
N,N--p-2

N,N-bis(2-hydroxyethyl)-p-phenylenedi
amine sulfate

6.0()

N,N-diethyl-p-phenylenediamine sulfate

6.0()

N,N-diethyltoluene-2,5-diamine HCl

10.0()

N,N-dimethyl-p-phenylene diamine

6.0

N,N-dimethyl-p-phenylenediamine
sulfate
N-phenyl-p-phenylenediamine

6.0()

6.0

N-phenyl-p-phenylenediamine HCl

6.0()

N-phenyl-p-phenylenediamine sulfate

6.0()

64

-3,4-HCl

65

-p-

66

71
72
73

N,N--2,5-HCl
N,N--p-

2
2

, 1.5%
, 1.5%

74

N,N--p-

75

N--p-(CI76085)

76

N- -p- HCl(CI76086)

77

N--p-

78

o-

o-Aminophenol

2.0

, 1.0%

79

o-

o-Aminophenol sulfate

2.0()

, 1.0%

80

p-

p-Aminophenol

1.0

, 0.5%

81

p-

p-Aminophenol sulfate

1.0()

, 0.5%

82

Phenyl methyl pyrazolone

0.5

, 0.25%

83

p-

p-Methylaminophenol

3.0

, 1.5%

84

p-

p-Methylaminophenol sulfate

3.0()

, 1.5%

p-Phenylenediamine

6.0

85

p-

93

p-HCl

87

p-

(4)

88

89

90

92
93

INCI

86

91

-2,5-

-2,5-
-3,4-

p-Phenylenediamine HCl

6.0()

p-Phenylenediamine sulfate

6.0()

Resorcinol

5.0

Sodium picramate

0.1

, 0.05%

Tetraaminopyrimidine sulfate

5.0

, 2.5%

Toluene-2,5-diamine

10.0

Toluene-2,5-diamine sulfate

10.0()

Toluene-3,4-diamine

10.0

(1) : , ; , , ; ,

(2) , 1
(3)
(4) , 2

94

Methods of Toxicological Test


General Principles
1

1
2/
3
4*
5
6
7
8/
9*
10

* GB7919-87
OECD (OECD Guidelines for Testing of Chemicals)

3
3.1
,

3.2
3.2.1
3.2.2

3.2.3

95


Acute Oral Toxicity Test
1

OECD Guidelines for Testing of ChemicalsNo. 401, Feb. 1987


USEPA OPPTS Harmonized Test GuidelinesSeries 870.1100, Aug. 1998

4
4.1 Acute oral toxicity 24h

4.2 LD50Medium lethal dose


mg/kg g/kg

6
6.1
()

1mL/100g 2mL/100g

6.2

20%
3d~5d

96

6.3

4~6 10

10 5000mg/kg

6.4
6.4.1

6.4.2
24h 2~3
3h~4h

6.4.3 1d

6.4.4 14d

6.4.5 24h
24h
6.4.6 LD50--
6.5
LD50 LD50

LD50

)
1
7

1
2
3
4
5
6 LD50
7 LD50 95% 2
8

LD50

97

LD50mg/kg

50
50500
5005000
5000
2

mg/kg

xSDg
0

LD50 95%

98

14


Acute Dermal Toxicity Test
1

OECD Guidelines for Testing of ChemicalsNo.402Feb. 1987


USEPA OPPTS Harmonized Test GuidelinesSeries 870.1200Aug. 1998

4
4.1 Acute dermal toxicity

4.2 LD50, Medium lethal dose


mg/kg g/kg

6
6.1

6.2

200g~300g 2kg
3kg 350g450g
3d5d

6.3
4~6 10

10
2000mg/kg
99


6.4
6.4.1 24h
10%
200g300g 30cm240cm2 2kg3kg
160cm2210cm2 350g450g 46cm254cm2
6.4.2

24h
6.4.3
6.4.4 14d

6.4.5 1d

6.4.6 24h
24h
6.4.7 LD50--
6.5
LD50 LD50

LD50

1
1

LD50mg/kg

5
544
44350
3502180
2180

1
2
3
4
5
6 LD50
100

7 LD50 95% 2
8
2

mg/kg

xSD(g)
0

14

LD50 95%

LD50

101

/
Dermal Irritation/Corrosion Test
1

OECD Guidelines for Testing of ChemicalsNo.404April 2002


USEPA OPPTS Harmonized Test GuidelinesSeries 870. 2500Aug. 1998

4
4.1 Dermal irritation
4.2 Dermal corrosion

6
6.1

/
/
pH 2 11.5
LD50 200mg/kg
2000mg/kg
6.2

3d

102

6.3
6.3.1 24h
3cm3cm
6.3.2 0.5mLg2.5cm2.5cm

4h
2h

3min60min 4h

6.3.3 12448 72h 1


2448 72 h
2
6.3.4 14d
6.4
6.4.1 3cm3cm
2.5cm2.5cm
6.4.2 0.5mLg
1 14d
1

6.4.3 2


14

0
1
2
3
4

0
1
2

1mm
1mm

3
4
8

103

1 pH
2
3
4
5
6

0~0.5
0.5~2.0
2.0~6.0
6.0~8.0
3

1h

kg

24h

48h

72h

1
2
3
4

104

10

11

12

13

14

14

105

/
Acute Eye Irritation/Corrosion Test
1

OECD Guidelines for Testing of ChemicalsNo 405April 2002


USEPA OPPTS Harmonized Test GuidelinesSeries 870.2400Aug.1998

4
4.1 Eye irritation
4.2 Eye corrosion

4 48h
72h

6
6.1
0.1mL
0.1mL 100mg

pH 2 11.5

6.2
3
3d 24h

106

6.3
6.3.1 0.1mL100mg
1s
24h 24h
6.3.2 3
30s 30s
6.3.3 1244872h 4d 7d
72h
7d 21d
7d14d21d
1

24h
6.3.4 30s
1s 30s
30s 6.3.3
6.3.5 4s 1s 4s
30s 6.3.3
1

0
1
2
3
4

0
1
2

107

0
1
2
3
0
1
2
3
4


2448 72h
2
7

2A
2/3 11
22 7

2B
2/3 11
22 21

1 / 21

2/3 3 /1.5

2448 72h
3
3

0/2
7 0
7 0
821 0
/ 21 0
2/3 3 /=2

1 pH
2
3
4 12448 72h
4 30 4
5
6
7

108

30 4

1h

24h

48h

72h

4d

7d

109


Skin Sensitisation Test
1

OECD Guidelines for Testing of ChemicalsNo 406July 1992


USEPA OPPTS Harmonized Test GuidelinesSeries 870.2600Aug.1998

4
4.1 Skin sensitizationallergic contact dermatitis

4.2 Induction exposure

4.3 Induction period

4.4 Challenge exposure

10d~14d

5.1

Vc
5.2
3d~5d

5.3

5.4
/
30% 60%

110

2,4-2-
6
6.1 Buehler TestBT
6.1.1
20 10
6.1.2

2~3
80%

6.1.3
6.1.3.1 24h 4cm2~6cm2
6.1.3.2 0.2mLg
6h 7d 14d
6.1.3.3 14d~28d 0.2mL 2cm2cm
24h 6h
6.1.3.4 24h 48h 1
6.1.3.5 6.1.3.2 6.1.3.3

0
1
2
3
4

1mm 1mm

0
1
2
3
7

6.1.4
6.1.4.1 2
3
6.1.4.2
6.2
6.2 Guinea Pig Maximinatim TestGPMT
Freund Complete AdjvantFCA
111

6.2.1
105
2010
6.2.2

2~3
6.2.3
6.2.3.1 0d
2cm4cm0.1mL

1 11v/vFCA/
2
3 11v/vFCA/2

1 11v/vFCA/
2
3 11v/vFCA/ 50%w/v
6.2.3.2 7d
0.5gmL2cm4cm
48h
24h10%SLS0.5mL

6.2.3.3 21d
0.5gmL2cm2cm
24h

6.2.4
244872h
2
13
2

0
1
2
3

1
2

3
112

4
5
6 4
5
7
3

0~ 8
9~ 28
29~ 64
65~ 80
81~100

BT

24

48

24

48

24

48

1 2

3 4

1 2

2
%

0123

GPMT

1
%

24
48
72
24
48
72
24
48
72

0123

113

114


Skin Phototoxicity Test
1

Phototoxicity

UVA

5
5.1

8-
8-methoxypsoralen8-Mop
5.2
6
3d~5d

Vc
5.3 UV
5.3.1 UV 320nm~400nm UVA UVB 0.1J/cm2
5.3.2 6
mW/cm2
5.3.3 10J/cm2

(10000mJ / cm 2 )
(sec) =
(mJ / cm 2 / sec)
1mW/cm2 = 1mJ/cm2/sec
5.4
5.4.1 18h~24h
4 1 2cm2cm
5.4.2 1 1 2 0.2mLg
115

30min 1 3
UVA
5.4.3 12448 72h 2
5.4.4 1 2
5.4.2

1
2
3
4

0
1
2
3
4

1mm
1mm

0
1
2
3
4

8
116

2 2 1 1
6

1
2

3
4
5
6 3 4

7
3

1h

g
1

2 3

24h
4

2 3

48h
4

2 3

72h
4

2 3

1
2
3
4
5
6
1234 1

1h

(g)
1

2 3

24h
4

2 3

48h
4

2 3

1
2
3
4
5
6
1234 1

117

72h
4

2 3


Salmonella Typhimurium/Reverse Mutation Assay
1

OECD Guidelines for Testing of ChemicalsNo.471Adopted21July 1997

3
3.1 Reverse mutation
(prototroph)
3.2 Gene mutation
DNA
3.3 Base substitution mutation
DNA
transitiontransversion
DNA
DNA
3.4 Frameshift mutation
DNA
3.5 /Salmonella typhimurium/reverse mutation assay

his-his+
3.6 S9
PCB -
9000g 10min

S9
4

(-80)
( 0.1g 0.0001g)

118

6
6.1 0.5mmol/L -0.5mmol/L
L-MW 155
78mg
D-(MW 244)
122mg

1000mL
0.068MPa 20min 4
6.2

1.2g

1.0g

200mL
0.103MPa 30min 0.5mmol/L
-0.5mmol/L 20mL
6.3 Vogel-BonnerV-B E
100g
C6H8O7H2O
500g
K2HPO4
175g
NaNH4HPO44H2O
10g
MgSO47H2O

1000mL

1000mL 0.103MPa 30min 4


6.4 20%

200g

1000mL

1000mL
0.068MPa 20min
4
6.5

7.5g

480mL
V-B E
10mL
20%
10mL
0.103MPa 30min
25mL 37 24h
6.6

2.5g

5.0g
1.0g
K2HPO4

500mL
0.103MPa 30min 4
6.7 1.65mol/L KCl+0.4mol/L MgCl2
KCl
61.5g
40.7g
MgCl26H2O

500mL
0.103MPa 30min 4

119

6.8 0.2mol/L pH7.4


2.965g
NaH2PO42H2O
29.015g
(Na2HPO412H2O)

500mL
0.103MPa 30min 4
6.9 S9

S9
100L
S9

20L

380L
0.2mol/L
500L
IINADP
4mol
6-G-6-P
5mol
II 6-
S9
S9
6.10
6.10.1

15g

944mL
V-B E
20mL
20%
20mL
0.5g/100mL
10mL
0.5mmol/L
6mL
20%V-B

6.10.2 /

15g

940mL
V-B
20mL
20%
20mL
0.5g/100mL
10mL
0.5mmol/L
6mL
8mg/mL 0.02mol/LNaOH
3.15mL
8mg/mL 0.02mol/L HCl
0.25mL
20minVB -
50/

6.10.3

7.5g

500mL
0.103MPa 30min

120

7
7.1
TA97TA98TA100 TA102
7.2

1
1

TA 97
TA 98
TA100
TA102

+
+
+
+

+
+
+
+

+
+
+
+

+
+
+
-

90-180
30- 50
100-200
240-320

+
rfa

+
R

*
+ +

uvrB pAQ1

7.2.1

37 24h

7.2.2
rfa

0.1mL 0.1%
37 24h
rfa

7.2.3
R R

0.1mL37 24h

R R R
7.2.4
uvrB

0.1mL
15W 33cm8 37 24h
uvrB
121


7.2.5
pAQI
0.1mL / 37
24h
/
pAQI pAQI
7.2.6

0.1mL 2mL
37 48h

7.2.7 -
S9

2
2

S9

TA97

ICR191

C
2,4,7--9-
4--O-
4--N-

2-
a

6.0
1.5
1.0
0.25
0.5
0.20
20
0.5
1.0
10
1.0

+
+

124
76
1640
inh
inh
8377
2160
528
174
1742
337

TA98
3123
3
63
inh
inh
8244
1599
292
23
6194
143

TA100

TA102

47
3000
185
inh
inh
400
798
4220
2730
3026
937

592
188
0
2230
2772
16
0
287
6586
261
255

inh
8 S9
8.1
PCB
200g 500mg/kg
200mg/mL 12h

- 200g
80mg/kg 80mg/kg- 3 16h

122


8.2 S9
75%
0.15mol/L 0.15mol/L
0.15mol/L 3mL
4 9000g 10minS9
2 mL ~3 mL-80
S9
S9

DMSO95%

100L
9

5mg/

10

11
11.1
5mL
37100 /min 10h 12
109
11.2
0.5mmol/L -0.5mmol/L 2.0mL
45 0.1mL 0.1mL
S9 0.5mL
37 48h

S9 S9

S9 S9
12

123

1
2
3
4

5 Ames 1
6
13

Ames

mg/

TA97

TA98

TA100

TA102

- 9 +S9 S
- 9 +S9
- S9 +S9
S
- 9 +S9 S

124


In Vitro Mammalian Cells Chromosome Aberration Test
1

OECD Guidelines for Testing of ChemicalsNo.473July 1997

4
4.1 Structural aberration

4.1.1 Chromosome-type aberration

4.1.2 Chromatid-type aberration

4.2 Mitotic index

6
6.1
6.1.1

methyl methanesulphonateMMSethyl methanesulphonate


EMSethyl nitrosourea Cmitomycin C
4--N4-nitroquinoline-N-oxideabenzo
apyrene
cyclophosphamide
6.1.2

125

6.1.3
6.1.3.1
/

6.1.3.2
S9 DMSO
0.5%
6.1.3.3
1
pH
osmolality
2

degree of confluencyviable cell counts


mitotic index
3
3
2 10

50%

5L/mL5mg/mL 0.01mol/L

S9

6.1.4 MEMEagle
100IU/mL 10%
6.1.5
S9 S9 mixS9 Aroclor 1254
-S9 Ames S9
1%~10%S9 mix S9mix

S9
0.125mL
0.02mL
MgC120.4mol/L
KC11.65mol/L
0.02mL
-6-
1.791mg
NADP
3.0615mg
MEM 1mL
6.2
6.2.1

CHOCHL

126

6.2.2 3
6.2.3 CO2
6.2.4 S9 mix
S9 mix S9 mix
3h~6h Hanks
3 10% 24h 2h~4h
4h 1g/mL
, S9 mix
S9 mix 24h

6.2.5 0.25% 10%


1000rpm~1200rpm
5min~7min 0.075mol/L KC1
3:1
6.2.6 100
2n2 200
100 2n2

6.3 X2
6.4
1
2

2
3
S9 S9 mix

4
1
2
pH osmolality
3
DMSO

127


5
1

g/mL
/mL

/mL

g/mL

g/mL

+S9

-S9

+S9

-S9

%
+S9

-S9

128


In Vitro Mammalian Cell Gene Mutation Test
1

GB15193 15193.12202003
OECD Guidelines for Testing of ChemicalsNo.4761997

Forward mutation

Mutant frequency
4

trifluorothymidineTFT
6-6-thioguanine6-TG
8-azaguanineAG TFT

6
6.1
6.1.1
6.1.1.1
/

6.1.1.2
S9 DMSO
0.5%
6.1.1.3
6.1.1.3.1
pH osmolality
6.1.1.3.2
total
growth
129

6.1.1.3.3
4
2 10

10%20% 10%

5L/mL5mg/mL 0.0lmol/L

S9

6.1.2

6.1.2.1
ethyl
methanesulfonate-EMSHPRT methyl methanesulphonateMMSTK
ethyl nitrosourea-ENUHPRT
3- 3-methylcholanthrene HPRT TK
cyclophosphamideTK N-N-nitroso-dimethylamineHPRT 7,12HPRT
6.1.2.2

6.1.3 HPRT V-79


CHOTK L5178YTK6

6.1.4 V-79 CHO


MEMEagle 10% L5178Y TK6
RPMI 1640 10%
6.1.5
6.1.6 6-6-TG 5g/mL10g/mL
TFT 3g/mL
6.1.7 THMG/THG
THMG 24h
THG THMG
1d3d
THMG

510-6mol/L

510-5mol/L

410-7mol/L

110-4mol/L
6.2
6.2.1 HPRT
6.2.1.1 1d 37C
6.2.1.2 S9-mix S9-mix
130

3h~6h
Hanks
6.2.1.3 3d 7d
3 7d
8 3h 6-TG 5g/mL10d

6.2.1.4 X
6.2.2 TK L5178Y 96
6.2.2.1 5105/mL 1%37
3 PBS 2
10% RPMI 1640 2105/mL
6.2.2.2 PE00 8 /mL
96 0.2mL 1.6 / 1~2 375% CO2
12d
6.2.2.3 6.2.2.1 2d
106/mL
6.2.2.4 PE2 2d 2d
6.2.2.2 96 12d
6.2.2.5 TFT MF 2d
1104/mL TFT 3g/mL 96
0.2 mL 2000 / 2~4 375% CO2
12d
6.2.2.6
6.2.2.6.1 PE0 PE2
-lnEW/TW
EW TW
PE=
1.6
1.6
6.2.2.6.2

%RS
PE0
100
%RS=
PE0
6.2.2.6.3 MF
-lnEW/TW/n
EW TW
MF10-6=
n 2000
PE2

1
2
%RS 20%

131

2
3
S9 S9 mix

4
pH

DMSO

5
8

132


In Vivo Mammalian Bone Marrow Cell Chromosome Aberration Test
1

OECD Guidelines for Testing of ChemicalsNo.475April 1997

Chromosome-type aberration

Chromatid-type aberration

Numerical-type aberration

6
6.1
5
3~5 20%

6.2
6.2.1

6.2.2

6.2.3
50% 3

2000mg/kg 2000mg/kg
133

2000mg/kg/BW/d 14
1000mg/kg/BW/d 14
6.3

6.3.1

6.3.2

triethylenemelamineethyl methanesulphonateethyl
nitrosonrea
Cmytomycin Ccyclophosphamide

6.4

1 , 1
12h~18h 2 1 24h
12h~18h
4h 4mg/kg
3h5h 4h5h
6.5
6.5.1
6.5.2 5mL 10mL

6.5.3 1000rpm 5min7min


6.5.4 0.075mol/L KCl 7mL 37
7min 1mL2mL =13 1000rpm 5min
7min
6.5.5 7mL 15min 1000rpm 7min
6.5.6 1~2
6.5.7
6.5.8
6.5.9
6.6
6.6.1 500~1000

6.6.2 100

2n2
Gap
X2

6.7

134

1
2
3
4
5

6
7
8
7

135


Mammalian Erythrocyte Micronucleus Test
1

GB14924
OECD Guidelines for Testing of ChemicalsNo.474Adopted21July 1997

Micronucleus

24mm
50mm
6

7
7.1
56 30min

7.2 Giemsa

3.8g

375mL

125mL
136

375mL
37 48h

7.3 1/15mol/L pH7.4


19.077g
Na2HPO412H2O
1.814g
KH2PO4

1000mL
pH pH
7.4
Giemsa 6 1/15mol/L

25g30g
150g200g 3~5d
20%

LD50 1/21/51/101/20 -
LD50 5g/kg 5g/kg 3
10
40mg/kg
2000mg/kg/BW/d 14
1000mg/kg/BW/d 14
/

30h
24h 6h
10

11
11.1

18~24h36~48h

11.2

2cm3cm

11.3
5min

137

11.4

Giemsa 10min15min 1/15mol/L

11.5

5min

11.6

2000

12
12.1
Poinsson u

12.2

13

1
2
3
4
5
6 1

138

g/kg

mg/kg

139


Testicle Cells Chromosome Aberration Test
1

GB15193 GB15193.82003

24mm50mm
5

6
6.1 0.04% 40mg 100mL
6.2 1 1g 100mL
6.3 0.075mol/L 5.59g 1000mL
6.4 /31v/v
6.5 60 60mL 100mL
6.6 pH6.8
6.6.1 1/15mol/LNa2HPO49.47 g1000mL
6.6.2 l/15mol/L KH2PO49.07g 1000mL
6.6.3 50mL 50mL
6.7
6.7.1 3.8g
375mL 125mL 37 48h 12

6.7.2 lmL 10mL pH6.8


6.8
7

6 8 30g
140

35g 5 20%

1/21/51/10 1/20LD50 LD50


5g/kg 5g/kg
40mg/kg C1.5mg/kg 2mg/kg
5
/

1
5d 1 12d14d
6h 0.04% 4mg/kg

10
10.1
1
0.075mol/L
10.2
10.2.1
15min25min
10.2.2 3110mL
15min 20min
10.2.3 60 1mL2mL
1000rpm 10min
10.2.4 0.5mL1.0mL

10.2.5 110 pH6.8 20min40min


10.3

5min

10.4
10.4.1

n 100

10.4.2
10.4.2.1
10.4.2.1.1
10.4.2.1.2
141

10.4.2.1.3
0.01
10.4.2.2 X-Y
X-Y X-Y 010
X Y XY

%X-Y X2

11

12

1
2

3
4
5

6
7
8
13

142


Subchronic Oral Toxicity Test
1

OECD Guidelines for Testing of ChemicalsNo.408Sep. 1998

4
4.1 Subchronic oral toxicity

4.2 No-adverse-effect level

mg/kg
mg/kgmg/mL

90d

6
6.1
6.1.1
6 8
10%

6.1.2
20

20 90d
28d

143

6.1.3

6.2

1000mg/kg

6.3
5d
7d

6.4
90d 28d

6.5
6.5.1

6.5.2

6.5.3

6.5.4

144

6.6
6.6.1

//
/*
**
**
*
***
*
6.6.2

2
3
4
7
7.1

7.2

7.3

1
2
3

4
5
6
7
8
9
10
11

145

12
13
14
15
16

146


Subchronic Dermal Toxicity Test
1

OECD Guidelines for Testing of ChemicalsNo.411May 1981

4
4.1 Subchronic dermal toxicity

4.2 No-adverse-effect level

mg/kg

90d

6
6.1

6.2
6.2.1

6.2.2
20

20
90d 28d

147

6.2.3

6.3

1000mg/kg

6.4
5d 24h

10%

90d 7d 6h 28d

6.5

6.6
6.6.1

6.6.2

6.6.3

148


6.6.4

6.7
6.7.1

//
/*
**
**
*
***
*
6.7.2

2
3
4
7
7.1

7.2

7.3

1
2
3

4
5
6
7
8

149

9
10
11
12
13
14
15
16

150


Teratogenicity Test
1

OECD Guidelines for Testing of ChemicalsNo.414January 2001


GB15193.142003

6
6.1
6.1.1 246-
6.1.2 50% 5.0mL 10.0mL1
60.0mL
6.1.3 3mL5mL 1g2g/100mL 1000mL

6.1.4 0.1g 10g 1000mL


6.1.5 A 200mL 10g 790mL
6.1.6 B
6.1.7 Bouins 2,4,6-75 20 5

6.2

6.3
10%
12

151

6.4
6.4.1
11 21
5d
6d15d 061015 20d

6.4.2
20d

6.4.3

6.4.4
1/2 95%v/v 2 3
1g2g/100mL 5
8h72h 6h48h 12 /d
A 1d2d B 2d3d

23 A 12
B 23

6 5 2 1213

7 1213 56 4 35

6.4.5
1/2 Bouins

1 1
152

2 2

3 3

4 4

6.5
2
T

10 10
100 100
300 100300 100

LD 50

1
2
3
4
5
6
7
8
9

153

/
Combined Chronic Toxicity/Carcinogenicity Test
1

GB14924
OECD Guidelines for Testing of ChemicalsNo.453Adopted12 May 1981

3
3.1 chronic toxicity

3.2 maximal no-adverse effect level

3.3 chronic adverse effect threshed level

3.4 chemical carcinogen

6
6.1

/
154


6.2

6
6.3

50 50
20
10
6.4

10%

10%

8.1
9

5% 7

8.2

155


20 / 10 / 12

1 18 24
24 30
2 25%

10%
2 18 24 50%
9

10
10.1

13 4 13
3

10.2

3 6 6 20

10.3
10

10.4
6 10

10.5
/

156

10.5.1

*/

***
*

10.5.2

* 10 *

11
11.1

= 100

11.2

1
2
3
4

11.3
3
50

1
2
3

12

157

4
5
6
7
8
9

10

158

Methods of Hygienic Chemical Test


General Principles
1

2
2.1
2.2 1
2.3
1
1

AAS/AES

3 SD

10 SD

GC

10

HPLC

10

0.005 A

0.015 A

(1)

X +3 SD

X(1)+10 SD

(1) X

2.4
2.5

AR

4.1
4.2
4.3

5
5.1 BB
B
cB=
mol/L
V
5.2 BB
B
B=
g/Lmg/Lg/L
V
159

5.3

BB
B
B=
mg/kgg/g

5.4 BB
VB
B=

V
5.5 V1V2
HCl1+2+++
=250+450+300+0.2
5.6

9.1

9.2
1cm

9.3

9.4
.
9

160


Mercury

253.7nm

0.01g 0.04g
1g 0.01g/g 0.04g/g
2

3
3.1 201.42g/mL
3.2 201.84g/mL
3.3 201.19g/mL
3.4 [H2O230]
3.5
3.6 [H2SO410]3.210mL 90mL
3.7 120g/L
12.0g 12.0g 100mL
3.8 200g/L 20g 250mL 3.320mL
100mL
3.9 100g/L
10g 100mL
3.10 3.95mL3.150mL
1L
3.11
3.12
3.12.1 [Hg=100mg/L]HgCl20.1354g 100mL
3.10 1000mL 3.10

3.12.2 [Hg=10mg/L]3.12.110.0mL 100mL


3.10
3.12.3 [Hg=1mg/L]3.12.210.0mL 100mL
3.10
3.12.4 [Hg=0.1mg/L]3.12.310.0mL 100mL
3.10
4

161

4.1
4.2
4.3
4.4
4.5
4.6
4.7
4.8
4.9
4.10

50mL10mL
100mL
250mL

5
5.1
5.1.1
1.00g 250mL

3.130mL 1 5mL3.25mL
2h
10mL 10mim

3.71.0mL 50mL
5.1.2
1.00g 100mL

3.550mg3.17mL
3.25.0mL 135140
3.1
2min 3.71.0mL 50mL

5.1.3
1.00g 50mL

3.15.0mL3.42mL
3.11 2h3.71.0mL 15min
20min3.6 25mL

5.1.4 2
0.5g1g

100C
0.5mL1.0mL

3.12.0mL3.0mL
3.41.0mL2.0mL
100C 20min
162

3mL

5min20min
100C

Mpa

min

0.5

1.5

1.0

3.0

1.5

5.0

10mL
3.70.5mL 10mL
5.2
5.2.1 3.12.400.100.300.500.701.002.00mL 100mL
3.6
5.2.2
3.82mL

5.3
3.6 5.2.2

Hg=

m1m0V

mV1
Hgg/g
m1g
m0g
VmL
V1 mL
mg
1

1. 1 1 1min

2.

163


3. 2min
2min

0.1g/L 0.3g/L 0.5g


0.002g/g 0.006g/g
7

8
8.1 5g/L 5g 1L
8.2 20g/L95%20g 1L 8.1

8.3 [HCl=10%]3.310mL 90mL


8.4 [Hg=0.01mg/L]3.12.410.0mL 100mL
3.10
9
9.1 105 2h
9.2 10mL25mL50mL
9.3
10
10.1
10.1.1
5.1.4
10.1.2
5.1.1
10.1.3
5.1.2
10.1.4
1.00g 50mL

3.15.0mL3.42.0mL
3.11 2h3.71.0mL 15min
20min 25mL
10.2
8.400.501.252.505.00mL 25mL
8.32.5mL 00.200.501.002.00g/L
164

10.3
10.3
10.3.1
300V 15mA 300 8.0mm
300mL/min 700mL/min
2s 12s8.2
11 0.5mL0.8mL
10.3.2
10.3.1
2mL5mL8.3 10mL

11

Hg=

10V

m1000
Hgg/g
1 g/L
0 g/L
VmL
mg
12

0g/L10g/L 95% 1.2%

165


Arsenic

4.0g/L 13.3g/L
1g 0.01g/g 0.04g/g
2

3
3.1 201.42g/mL
3.2 201.84g/mL
3.3
3.4 500g/L 500g 1L
3.5 1+1201.19g/mL100mL 100mL
3.6 [H2O2=30%]
3.7 [(NH2)2CS] 12.5g 80mL
12.5g 100mL
3.8 1g/L lg 1L
3.9 7g/L 7g 1L 3.8
3.10 100g/L
100g 1L
3.11 1+93.210mL 90mL
3.12 1g/L 0.1g 50mL95 100mL
3.13 [As=1g/L] 150 2h As2O30.6600g
10mL 3.8 2 3.123.11
3.1110mL 500mL
3.14 [As=10mg/L]3.131.00mL 100mL

3.15 [As=1mg/L]3.1410.0mL 100mL

166

4
4.1
4.2
4.3
4.4 150mL
4.5 10mL25mL
4.6
4.7
4.8
4.9
4.10 50mL
5
5.1
5.1.1 HNO3H2SO4
1.00g 150mL
3.110mL
20mL3.22mL
3.1
20mL 25mL

5.1.2
1.00g 50mL 3.3
1g3.42mL
550 4h6h1+1
3.520mL 25mL
5.1.3
0.5g1g

100C
0.5mL1.0mL

3.12.0mL3.0mL
3.61.0mL2.0mL
100C 20min
3mL

5min20min
100C

1
167

Mpa

min

0.5

1.5

1.0

3.0

1.5

5.0

10mL 10mL

5.2

5.2.1 1
45mA340V8.5mm500mL
Ar/min1000mL Ar/min12s
8s2mL
5.2.2 2
45mA340V8.5mm0.03Mpa
300mL Ar/min600mL Ar/min
12s10s1mL
5.3
3.1500.100.300.501.001.502.00mL 25mL
5mL1+13.55.0mL
3.72.0mL 2.0mL
3.9g/L

5.4
10.0mL 25mL
3.72.0mL 2.0mL 5.3

As=

10V

m1000
Asg/g
1g/L
0g/L
VmL
mg

0.24g/g4.59g/g
1.1
10.0 4.7 0.28.0
4.1 5.14.3 3.2
0.3g/g4.5g/g 100.3
99.098.1 98.5
7

168

0.03g
0.1g 1g 0.03g/g, 0.1g/g
8

9
9.1 113.2100mL 100mL
9.2 1mol/L3.255.5mL 944.5mL
9.3 201.19g/mL
9.4 200g/L
200g 1L
9.5 1g/L 0.1g 50mL95 100mL
9.6 100g/L 100g 1L
9.7 150g/L 150g 1L
9.8 400g/L 40g9.340mL 100mL

9.9 1020
9.10 100g/L 100g 1L
9.11 9.102h
9.12 4.0g3.115mL 500mL
9.13 2g/L 1750501.0g 520mL
10min 500mL
9.14
9.15 9.12+9.13+9.141+1+2

10
10.1 250mL125mL
10.2 50mL
10.3
10.4 1
11
11.1
11.1.1 HNO3H2SO4

1.00g 250mL 125mL


5mL 3.110mL15mL
3.25mL

169

3.1 20mL
50mL
10mL 1+12.0mL

2
3
4

1125mL
2
3

45mL
5

5
6 0.4mm

11.1.2
1.00g 50mL
9.610mL 3.31g
550 4h3.520mL
50mL 10mL
1+12.0mL
11.2
3.150.000.501.002.003.004.005.00mL
11.1.19.110mL
11.1.23.510mL 50mL
9.72.5mL 9.82mL 10min9.9 5g
9.155.0mL
1h9.14 5.0mL
1cm 410nm
11.3
11.1.1 11.1.2
9.13.5 10mL 50mL9.7
2.5mL 9.82mL 10min9.9 5g
9.155.0mL
1h9.14 5.0mL 1cm
410nm

12

As

10)V
mV1
170

Asg/g
1g
0g
VmL
V1mL
mg

2.00g 8.28.7 5.00g


5.98.7 2.00g 91.2
94.7% 5.00g 89.897.2%
13

1.7ng
5.7ng 1g 0.17g/g 0.57g/g
14

15
15.1 [HCl10]9.310mL 90mL
15.2 150g/L20g/L 15g 2g
100mL
15.3 5g/L 0.5g 100mL 0.5g

16
16.1
16.2 50mL
16.3
17
17.1
17.1.1 HNO3H2SO4
1.00g 125mL
3.110mL
20mL3.22mL
3.1
20mL 50mL
15.25mL 10min

17.1.2
171

1.00g 50mL 3.3


1g9.62mL
550 4h6h1+1
3.520mL 15.25mL 50mL
10min
17.1.3
1.00g
3.110mL15mL3.1
6mL 3.66mL
100C 2h
140C150C 4h 50mL
9.25mL
20mL 50mL 15.25mL
10min
17.2
3.1500.501.002.004.00mL 100mL
15.1 05.010.020.040.0g/L
2
2

193.7nm

0.4nm

1.5mA

588V

C2H2/

9s

1.0L/min

1.0/5.0

2mL

5mL
15.32.0mL

17.3
0.5mL 15.14.5mL 17.2
18

As=

10VVS1000

mV1
Asg/g
1g/L
0g/L
VmL
VSmL
V1mL
mg

2.09g/g12.12g/g 3.17.1
3.79.0
19

172

2.5g/g10g/g 94.3
84.2103%

173


Lead

0.15mg/L 0.50mg/L 1g 10mL


1.5g/g 5g/g
2

3
3.1 201.42g/mL
3.2 [HClO47072]
3.3 [H2O230]
3.4 1+13.1100mL 100mL
3.5 3.13.2 3+1
3.6
3.7 120g/L
12.0g 12.0g 100mL
3.8
3.8.1 [Pb=1g/L] 99.99 1.000g3.4
20mL 1L
3.8.2 [Pb=100mg/L]3.8.110.0mL 100mL
3.42mL
3.8.3 [Pb=10mg/L]3.8.210.0mL 100mL
3.42mL
3.9 MIBK
3.10 7mol/L
201.19g/mL30mL 50mL
4
4.1
4.2
4.3
4.4 10mL25mL50mL
4.5 100mL
4.6
174

4.7
4.8
4.9
4.10
5
5.1
5.1.1
1.00g2.00g

3.110mL 1
2mL3mL3.22mL5mL
2

1mL 10mL 25mL

5.1.2
0.5g1g

100C
0.5mL1.0mL

3.12.0mL3.0mL
3.31.0mL2.0mL
100C 20min
3mL

5min20min
100C

Mpa

min

0.5

1.5

1.0

3.0

1.5

5.0

10mL

3.70.5mL 3 10mL
5.1.3
1.00g 50mL

3.15.0mL3.32.0mL

175

3.6 2h3.7

1.0mL 3 15min20min 25mL


5.2
5.2.1 3.8.300.501.002.004.006.00mL 10mL

100
5.2.2

5.2.2 3.1010mL
MIBK3.9
3.105mL MIBK
6

Pb

10V

m
Pbg/g
1mg/L
0mg/L
VmL
mg

-0.46V

0.056g 0.19g 1g 0.56g/g


1.9g/g
7

8
8.1 HgNO32H2O 68.5mg KNO3 25.3g 3.1
0.63mL 1L
8.2 1+1201.19g/mL100mL 100mL
8.3 1+1 100mL 100mL
8.4 1g/L 0.1g 50mL 50mL

8.5 1+1 100mL 100mL


9

9.1
9.2 100mL
176

9.3
9.4
9.5

100mL
50mL

10
10.1
5.1.1 100mL
100mL
10.2
3.8.300.0500.100.200.400.701.00mL 6
100mL
10.3
1+1
3.41+1
8.3
8.1 2
10.4
10.1.210.1.110.0mL 25mL 2
8.41+1
8.51+1
8.20.3mL
50mL 2

-1.10

-1.10

rpm

2500

2000

40

60

-0.20

-0.20

-0.90

-1.00

30

30

20

20

20

1020

11
11.1
Pb=

m1-m0V

mV1
Pbg/g
m1g;
m0g
VmL
V1mL
mg

177

11.2

Pb=

h1m1

h2-h1m
Pbg/g;
h1
h2
m1g
mg

4 3
2.057.96% 82.7103.0%
12

0.3g1.0g1g0.3g/g
1g/g
13

14
14.1
14.2 1g/L 0.1g 100mL
14.3 1g/L0.5g
50mL950mL
1+18.53100mLl0mL2
1+18.22~3100mL
500mL
14.4 0.01g/L14.31mL
100mL
14.5 [HNO3=1%]3.110mL 990mL
14.6 200g/L20g50mL214.2
1+18.5pH8.5~9.014.4
14.11+18.2100mL
14.7 200g/L50g100mL214.2
1+18.5pH8.5~9.014.410mL~20mL
250mL
14.8 100g/L10g
20mL14.3100mL
14.9

178

15
15.1 125mL
15.2
16
16.1
5.1.1
16.2
125mL50mL
3.8.300.100.200.300.400.50mL125mL
14.550mL
14.72mL14.61mL14.228.5
14.82mL
14.45mLlmin
14.95l0nm

17

Pb=

m1m0

V
mV1
Pbg/g
m1g
m0g
VmL
V1mL
mg
1

1.
2.

3.
4.
5.
6. 72% 203

179


Methanol

15g/g 50g/g
2

3
3.1 1.0L
3.2 [C2H5OH=75%]3.175mL 100mL
3.3 GDX-10260 80
3.4 1540 1500
3.5
3.5.1 5.3.1 1.00mL 100mL 75
3.2 1.00v/v
3.5.2 5.3.2 5.3.3 1.00g 100mL
753.2 10g/L
3.6
3.7

4
4.1
4.2 2m2mm GDX-102
4.3 2m4mm 25 1540 1500 GDX-1023.3

4.4
4.5 01000.5
4.6 20mL65mL
4.7 0.5L1L1mL

5
5.1

180


14.2
170180180
40mL/min40mL/min500mL/min
24.3
7590150
30mL/min30mL/min300mL/min
5.2

753.2

5.3
5.3.1

753.2
5.3.2 10g 4.4 50mL
3.62g3.71 3.130mL
50mL
5.3.3 - 5g 75
3.25mL 40 20min

5.4
5.4.1 5.3.1 50mL 7 3.5.1
0.250.501.002.004.007.0010.0mL 753.2
0.0050.0100.0200.0400.0800.1400.200%v/v
1L v/v

5.4.2 5.3.2 50mL 7 3.5.2


0.250.501.002.004.007.0010.0mL 753.2
0.0500.100.200.400.801.402.00g/L 1L
g/L
5.4.3 5.3.3 3.5.200.100.501.002.00
3.004.00mL 753.2 10.0mL 00.100.501.002.00
3.004.00g/L 40 20min 1mL
g/L
5.5
1L 1mL

CH3OH=

V1000
m
181

CH3OHg/g
g/L
VmL
mg
3.5.1

CH3OH=

1100K
CH3OH10-6

1v/v
K

1 2
0.617min 2 1.473min

182


Free Hydroxide

GB/T601-2002 4.2
2

pH9.2

0.20mg 2g 0.01%
3

4
4.1 [cHCl=0.100mol/L] GB/T601-2002 4.2
5
5.1
5.2
5.3
5.4
5.5 150mL25mL
6
6.1
6.1.1 1g 9mL 25mL
5min~10min pH

6.1.2 pH
pH pH 11
6.2
6.2.1 1g2g 1mg 150mL
3h 4h
100mL
5min~10min
183

4.1 pH 9.6 pH
9.2
6

NaOH=

40cV100

m1000
NaOH%
cmol/L
VmL
mg
40g/mol

184

pH
pH
1

pH
pH

pH

EE0+0.059 lg[H ]25


EE00.059 pH
E0
25 pH 59.1mV 59.1mV
pH pH

CO2
3.1 105 2h KHC8H4O410.12g
1L 20pH 4.00
3.2 105 2h KH2PO43.40g
Na2HPO43.55g 1L 20pH
6.88
3.3 NaB4O710H2O3.81g 1L
20pH 9.22
pH A
3

4
4.1
4.2
4.3
4.4 50mL
5
5.1
5.1.1
1 0.1g CO2 10 40

7080

5.1.2

185

5.2
5.2.1 4.2 24h
5.2.2 4.1 pH

5.2.3
1min pH 0.1

19 622
0.16%1.94%

A
1

pH
pH

4.01

6.98

9.46

4.01

6.95

9.39

10

4.00

6.92

9.33

15

4.00

6.90

9.27

20

4.00

6.88

9.22

25

4.01

6.86

9.18

30

4.01

6.85

9.14

35

4.02

6.84

9.10

40

4.02

6.84

9.07

45

4.03

6.83

9.04

50

4.03

6.83

9.01

186


Cadmium
1

0.007mg/L
0.023mg/L 1g 0.18g/g 0.59g/g
2

3
3.1 20=1.42g/mL
3.2 [HClO4=70%72%]
3.3 [H2O2=30%]
3.4 1+13.1100mL 100mL
3.5 3.13.23+1
3.6
3.6.1 [Cd=1g/L][Cd= 99.99%]1.000g1+1
3.420mL 250mL 1L
3.6.2 [Cd=100mg/L]3.6.110.0mL 100mL
1+13.42mL
3.6.3 [Cd=10mg/L]3.6.210.0mL 100mL
1+13.42mL
3.7 MIBK
3.8 7mol/L20=1.19g/mL30mL 50mL
3.9 120g/L
12.0g 12.0g 100mL
3.10

4
4.1
4.2
4.3 10mL25mL
4.4
187

4.5
4.6
4.7

5
5.1
5.1.1
1.00g2.00g

3.110mL
2mL3mL3.22mL5mL

1mL 10mL 25mL

5.1.2
0.5g1g

100C
0.5mL1.0mL

3.12.0mL3.0mL
3.31.0mL2.0mL
100C 20min
3mL

5min20min
100C

Mpa

min

0.5

1.5

1.0

3.0

1.5

5.0

10mL

3.90.5mL 1 10mL
5.1.3
1.00g 50mL

3.15.0mL3.32.0mL
3.10 2h

188

3.91.0mL 1 15min20min 25mL


5.2
5.2.1 3.6.300.501.002.003.004.005.00mL 50mL
1+1
3.41mL 00.100.200.40
0.600.801.00mg/L
100
5.2.2

5.2.2 3.810mL
MIBK3.7 2
3.85mL MIBK

Cd

10V

m
Cdg/g
1mg/L
0mg/L
VmL
mg

0.25g/g1.00g/g
0.73%8.73%228
85.8%101.3%
0.25g/g1.00g/g
0.69%6.90%252 85.6%
102.0%

Cd2+-0.62V

0.025g 0.082g 1g
0.25g/g 0.82g/g
8

9
9.1 HgNO32H2O 68.5mg KNO3 25.3g
3.10.63mL 1L
9.2 1+1201.19g/mL100mL 100mL
189

9.3 1+1 100mL 100mL


9.4 1g/L 0.1g 50mL 50mL

9.5 1+1 100mL 100mL


10
10.1
10.2 100mL
10.3 100mL
10.4 50mL
10.5
11
11.1
5.1.1 100mL
11.2
3.6.300.0500.100.200.400.70 1.00mL 7
100mL
11.3
3.41+1
9.3
1+1
2
2

-1.10

-1.10

rpm

2500

2000

40

60

-0.20

-0.20

-0.90

-1.00

30

30

20

20

20

1020

11.4

11.211.110.0mL 25mL
2 1+19.51+1
9.20.3mL
50mL 2

12
12.1
Cd=

m1m0V
mV1
190

Cdg/g
m1g
m0g
VmL
V1mL
mg
12.2
h1m1
Cd=
h2h1m
Cdg/g
h1
h2
m1g
mg

3
2.44%9.35% 81.3%104%

13

191


Strontium

600

EDTA 0.06mg/L
0.2mg/L 1g 3g/g 10g/g
2

3
3.1 MgO
3.2 20=1.42g/mL
3.3 EDTA 0.2mol/LNa2 C10H14N2O82H2O74.4g
NaOH8.0g 1L
3.4 50g/L[LaNO336H2O] 117g 1L
58.65g20=1.19g/mL250mL
1L
3.5 [Sr=1g/L][SrNO32] 2.4153g
3.220mL 1L GBWE080242
3.6 [Sr=100mg/L]3.510.0mL 100mL
3.21mL

4
4.1 10mL50mL50mL1+4 6h

4.2
4.3
4.4

192

5
5.1
20mm 1.00g 50mL
3.10.50g

600C 4h
1+310mL1+110mL EDTA 1h
50mL
5.2
460.7nm1.3nm7.5mm1.60kg/cm29.4L/min
0.25kg/cm22.2L/min

5s
5.3
6 10mL 3.600.100.300.500.70
1.00mL1+32mL 0.001.00
3.005.007.00 10.0mg/L EDTA 3.30.2mL 3.4
0.2mL
5.4
5.1 10.0mL EDTA 3.30.2mL
3.40.2mL

Sr=

m1m0V

mV1
Srg/g
m1g
m0g
VmL
V1mL
mg

21.6g/g1485g/g 0.36%5.1%
96.4%106%

193

NaF 0.006mg/L 0.02mg/L


0.5g 0.6g/g 2g/g
8

9
9.1 <1.0s/cm
9.2 [H2O2=30%]
9.3 0.12mol/L20=1.19g/mL10mL 1L
9.4 0.1mol/L 4g 1L
9.5 0.1mol/L 0.42g 100mL
9.6 20mmol/L99%1.3mL 1L

10
10.1 10mL50mL1+4 6h

10.2
10.3
10.4
10.5
10.6
10.7
10.8 0.25m
11
11.1
11.1.1
20mm 0.5g
3.22mL3mL
100 1h3.21.0mL 9.2
2.0mL
200
9.32mL3mL 100 10mL 50mL
9.4 pH 25mL
5.00mL 10.0mL10000rpm 10min
0.25m 9.5
10mL
194

11.1.2
0.5g1.0g 50mL
3.25mL 90 1h 180 5h
2409.32mL3mL 100 10mL
9.4 pH 25mL

5mL 10mL10000rpm 10min 0.25m


9.5

10mL
11.1.3
0.5g1.0g 50mL 1%v/v 25mL
20min30min 10min
5mL9.4
pH 10mL
10000rpm 10min 0.25m
9.5 10mL

11.2
IonPac CS12250mm4mmCG1250mm4mmCSRS-ULTRA
20mmol/L
0.70mL/min
50L
3S
7psi
50mA

11.3
11.3.1
6 10mL 3.600.050.100.400.80
1.00mL 0.000.501.004.008.0010.0mg/L
0.5mL1.0mL
11.3.2
0.5mL1.0mL

12

Sr=

VN

M
Srg/g
mg/L
VmL
N
mg
13

195

1
+

1: Na (3.66min); 2: NH4 (4.36min); 3: K+(5.56min); 4: Mg2+(7.18min); 5: Ca2+(8.37min); 6: Sr2+(10.35min)


+

2
1: Ca2+(8.88min);

2: Sr2+(10.33min)

196


Total Fluorine
1

pH5.2
ALC
5g 17g 0.5g 0.01%w/w
0.034%w/w
2

3
3.1 80g/L 8g 100mL
3.2 1+1201.84g/mL100mL 100mL
3.3 0.1mol/L20=1.19g/mL0.83mL 100mL
3.4 20=1.049g/mL
3.5 3.85g/LALC C19H15NO8
0.385g 10mL3.13.3
pH 4.5 100mL

3.6 CH3COONa3H2O100g 200mL 3.4


11mL pH 5.2 1L
3.7 4.33g/LLaNO36H2O4.33g 1L
3.8

3.9 [F =100mg/L] 120 2h 0.221g


1L

3.10 [F =10mg/L]3.910.0mL
100mL
4
4.1
4.2
4.3 1
5
5.1
0.5g5.0g3.13.0mL
5min 50mL 3.240mL
1 130
140150 20mL 200mL
197

180mL

11000mL 21m 3
T 4350mL 5
6200C 7 8
(200mL )

10

5.2

3.1000.501.001.502.003.004.005.00mL 50mL

05.0010.020.030.040.050.0g F 3.5
1.00mL3.65.0mL3.71.0mL 3.815.0mL
1h 620nm 1cm

5.3
5.120mL 50mL 5.2

F=

m1V2

mV110000
F%w/w
m1g
V1mL
V2mL
mg

0.04%w/w0.08%w/w
1.30%4.10% 93.0%106.5%

198


Total Selenium

-
2,3- pH1.52.0 4,5-
2.110-3g
7.010-3g 1g 2.110-3g/g 7.010-3g/g
2

3
3.1 201.42g/mL
3.2 [HClO47072]
3.3 201.19g/mL
3.4 1+43.350mL 200mL
3.5 0.1mol/L3.38.3mL 1000mL
3.6 200.892g/mL
3.7 50g/L
C10H14N2O8Na22H2O
EDTA-2Na50g 1L
3.8 100g/L
NH2OHHCl100g 1L
3.9 pH pH0.55.0

3.10 2g/L
C22H18O5S0.2g 3.6
100mL
3.11 --3.7
50mL3.850mL 3.102.5mL 500mL

3.12 1+13.6100mL 100mL


3.13

3.14 2,3-[C10H6NH22 DAN]2g/L


2,3- 200mg 250mL 3.5100mL
15min 20mL 5min

2,3- 1cm

3.15
3.16 [Se=100mg/L] 0.1000g3.1
3.22mL 3h4h3.4
8.4mL 2min 1L
199

3.17 [Se=0.1mg/L]3.163.5
1.00mL 0.100g

1+1 4h

4.1 100mL
4.2 4cm
4.3 50mL
4.4
4.5
4.6
4

5
5.1
1.00g2.00g

3.110mL
2mL3mL3.22mL5mL
3.44mL

5.2
3.1700.100.250.500.751.002.00mL 100mL

5.3
50mL
3.1110mL3.12
3.4 pH 1.52.0[ pH0.55.0 3.9]
2,3-3.141mL
5min3.13
4.0mL 2min
379nm 519nm

Se=

m1m0

m
Seg/g
m1g
m0g
mg
7

200

3
92.098.0 4.98.0

201


Boric Acid and Borate
1

-H

-H
1.17g3.86g1g
11.7g/g38.6g/g
2

3
3.1 -pH=6.050gEDTA4.5g150mL
3.5mL
3.2 -H
3.2.1 -HH[NH2C10H4(OH)(SO3H)SO3Na3/2H2O] 18g1L
10%
10mLpH1.520mL401h16h
-H34
802h3h

3.2.2 -H5g/L-H3.2.10.5g2.0g100mL
<50
3.3 10g/L1g100mL
3.4 1+9201.19g/mL100mL 900mL
3.5 1+1 100mL 100mL
3.6
3.6.1 [H3BO3=1g/L]H3BO31.000g250mL
1L
3.6.2 [H3BO3=20mg/L]3.6.110.0mL500mL

4
4.1
4.2 25mL
5
5.1
5.1.1 1.0g200mL3min

5.1.2
202

5.1.2.1
1g2g30mL3.35mL
500
3.410mL100mL
5.1.2.2
1.0g3.5
200mL3.5
5000rpm

5.2
3.6.200.501.002.004.006.008.0010.0mL
010.020.040.080.0120160200g5.1.15.1.2
25mL10mL-3.12.0mL
-H3.2.22.0mL2580min
415nm1cm
6

H3BO3=

(m1m0)V

mV1
H3BO3g/g
m1g
m0g
VmL
V1mL
mg

0.003%2.05%
0.67%5.9%81.2%117.7%
68%90%76%99%

203


Selenium Disulfide
1

- 2,3- pH1.5
2.0 4,5-
2

4.810- g 1.610- g 1g

4.810- g/g 1.610- g/g


3
3.1 201.42g/mL
3.2 [HClO47072]
3.3 [H2O230%]
3.4 1+93.210mL 90mL
3.5 -1+9
3.4+3.34+1
3.6 201.19g/mL
3.7 1+43.650mL 200mL
3.8 0.1mol/L3.68.3mL 1000mL
3.9 50g/L
C10H14N2O8Na22H2O
EDTA-2Na50g 1L
3.10 100g/LNH2OHHCl100g 1L
3.11 pH pH0.55.0

3.12 2g/LC22H18O5S0.2g 3.14


100mL
3.13 --3.9
50mL3.1050mL 3.122.5mL 500mL

3.14 1+1 100mL 100mL


3.15

3.16 2,3-[C10H6NH22 DAN]2g/L


2,3- 200mg 250mL 3.8100mL
15min
3.1520mL 5min

2,3- 1cm
204


3.17
3.18 [Se=100mg/L] 0.1000g3.1
3.22mL 3h4h3.7
8.4mL 2min 1L
3.19 [Se=0.1mg/L]3.183.8
1.00mL 0.100g

1+1 4h

4.1 100mL
4.2 4cm
4.3 50mL
4.4
4.5
4.6
4.7
4

5
5.1
5.1.1 1.00g2.00g 50mL
3.175 -3.510mL20mL 3min

5.1.2 1.00g2.00g 50mL 3.17


5 -3.520mL40mL 4h 3min
10.0mL20.0mL
5.2
3.1900.100.500.701.001.502.00mL 50mL

5.3
50mL
3.1310mL1+1
3.14
1+4
3.7 pH pH1.52.0 pH0.55.0 3.11

2,3-3.161mL
5min
3.154.0mL 60 3min
4000rpm 40min 379nm 519nm

205

SeS2=

(m1m0)V

1.812
mV1
SeS2 SeS2 g/g
m1g
m0g
V-mL
V1-mL
mg
1.812Se+4 SeS2

84.0%94.0% 6.4%8.9%

206


Formaldehyde

35--14

H2
O
O
O
O
C
O

HCH+NH3+2CH3CCH2CCH3CH3CCH2C CCH2CCH3+3H2O

HC
CH

N
H

1.8g 6.0g 1g 18g/g


60g/g
3

3.1

250g/L 25g 100mL

3.2

[=0.2] 25g

3mL 0.2mL 100mL


3.3

250g/L 25g 3mL 100mL

3.4 40g/L 4g 100mL


3.5 [H2SO4=3%]201.84g/mL3mL 97mL

3.6 [H2SO4=10]201.84g/mL10mL 90mL

3.7

10g/L 1g 5mL 95mL

0.1g 0.4g
3.8

0.05mol/L 13.0g 35g 100mL 3

1L
3.9

[c1/6K2Cr2O7=0.1000mol/L] 1202

4.9031g 1L
3.10

0.1mol/LNa2S2O3.5H2O26g

16g 1L 0.4g 0.2g

3.925.00mL 500mL 2.0g


207

[H2SO4=10]3.620mL 10min 150mL


3.103.72mL

cNa2S2O3

c25.00

V1-V0

cNa2S2O3mol/L
c[c1/6K2Cr2O7]mol/L
V1mL
V0mL
3.11

Formalin 1g 1L

HCHO

20.0mL 250mL 3.850mL


3.415mL 15min [H2SO4=3]3.520mL
15min3.10
3.72mL

HCHO=

V1-V0c151000
V

HCHOmg/L
VmL
V0mL
V1mL
cmol/L
151/2HCHOg/mol
3.12

3.111mg/L

4mg/L
4

4.1

50mL

4.2

10mL

4.3

4.4

4.5

4.6

5
5.1

1.0g 50mL 3.125mL

40 1h

208

3000rpm
5.2

5.00mL 10mL 3.25.00mL

40 30min 30min 5.00mL


3.35.00mL 1cm
414nm A
5.00mL3.25.00mL
AS A0

HCHO

AAo

AsAo

1
m

HCHOg/g
mg/L
A
AS
A0
VmL
mg
7

10%

209


Thioglycollic Acid

5.8ng 20ng
0.5g 46g/g
0.15mg/g

3.1

3.2

3.3
3.4 [H2SO4=10]201.84g/mL10mL 90mL

3.5 [HCl=10]201.19g/mL10mL 90mL


3.6

10g/L 1g 5mL 95mL

0.1g 0.4g
3.7

500g/L 50g

100mL
3.8

[c1/6K2Cr2O7=0.1000mol/L] 1202

4.9031g 1000mL

3.9

0.1mol/LNa2S2O3.5H2O26g

16g 1000mL 0.4g 0.2g

3.825.00mL 500mL 2.0g


3.420mL 10min 150mL
3.62mL

210

cNa2S2O3

C25.00
V1-V0

cNa2S2O3mol/L
C[c1/6K2Cr2O7]mol/L
V1mL
V0mL
3.10

0.05mol/L 13.0g 35g 100mL

3 1000mL3.9

25.00mL 500mL 150mL


3.93.62mL

175mL 0.05~0.20mL 3.62mL


3.9
c1/2I2

V2-V0c1
V3-V4

c1/2I2mol/L
c1mol/L
V2mL
V3mL
V0mL
V4mL
3.11

1000mg/L3.10.5g

500mL 1mL
0.501.002.005.0010.020.050.0
80.0mg/L
25.0mL 250mL 25mL 20mL
3.62mL3.10

cHSCH2COOH

92.1cV1-V0210001000
V1000

cHSCH2COOHg/mL
cmol/L
V1mL
V0mL
VmL
92.1g/mol
2

211

4.1

4.2

4.3

4.4

5
5.1

0.5g 100mL

20min3.32mL
14000rpm 15min 0.25m
5.2

AS11-HC2504mm I.D.AG11-HC504mm I.D.

ASRS-ULTRA
25mmol/LNaOH+1%
0.85mL/min
1.0mL/min 50mA
5psi

25L

5.3

0.5mL1mL

5.4

0.5mL1mL 5.1

V
=
m
g/g
mg/L
VmL
mg

212

mv

min
1

AS11-HC,AG11-HC25mmol/LNaOH+1% 0.85mL/min
ASRS-ULTRA 50mA25LTR=8.43min

2HSCH2COOHI2 HOOCH2C-S-S-CH2COOH2HI
0.46mg 2g 0.023%w/w

10

10.1

10.2

11

213

11.1

2g 3.520mL 50mL

3.35mL 5min

11.2

3.62mL 3.10

1min

12

HSCH2COOH

92.1cV2100
m1000

HSCH2COOH%w/w
cmol/L
VmL
mg
92.1g/mol
2

13

214


Hydroquinone and Phenol

-
0.001g 0.003g 0.003g 0.01g 1g
2g/g 7g/g 7g/g 23g/g
3

3.1

3.2

[=1g/L] 0.1000g

3.1 100mL
4
3.3

[=1g/L] 0.1000g

3.1 100mL 4

4.1

4.2

4.3 0.45m
4.4
5
5.1

1.0g

3.1 10mL 15min 0.45m


5.2

C18 150mm3.9mm5m
+=60+40
215

1.0mL/min

280nm
5.3

3.23.3 10.050.0100200mg/L

5L
mg/L
5.4

5L

V
m

g/g
mg/L
VmL
mg
7

DB-1 30m0.25mm50C1min 6C/min 190C

2min250C230C130100kPa

3030050amu/s4min5min
1.4kV

216

0.03g 0.05g 0.10g


0.16g 1g 150g/g 250g/g
500g/g 830g/g
10

10.1

[99.9%]

10.2

[4g/L] 0.400g

100mL
10.3

[2g/L] 0.200g

100mL
11

12
12.1

1.0g 10mL 10.1 1min

10.1
12.2

2m 3mm
10% SE-30Chromosorb W AW DMCS 6080
220280

30mL/min 50mL/min 500mL/min

12.3

5mL 10.201.502.002.503.00mL 10mL

10.1 00.600.801.00 1.20g/L

5mL 10.300.501.002.003.004.00
5.00mL 10mL 10.1 00.100.200.40
0.600.80 1.00g/L
10L 2.0L
g/L
12.4

2.0L

217

13

V1000
m

g/g
g/L
VmL
mg
14

2
1

15

0.045g 0.09g
0.15g 0.3g 1g 90g/g 180g/g
300g/g 600g/g
16

17

17.1

17.2

17.3

0.45m

18

218

18.1

18.2

280nm

18.3

5L

18.4

19

20

219


Sexual Hormones

7 -
-//
7

1g
1
1

0.02

0.04

0.01

g/g

40

80

20

0.02

0.002

0.002

0.003

40

3.1

3.2

3.3
3.4 [H2SO42]201.84g/mL2mL 98mL

3.5
3.5.1

[2g/L]

0.200g3.1 100mL

3.5.2

[600mg/L]

0.600g3.1 100mL 1mL


6.00mg 10.0mL 100mL
3.1
3.5.3

[600mg/L] 0.600g3.1

100mL 1mL 6.00mg


10.0mL 100mL 3.1
220

3.5.4

3.5.150.0mL3.5.2

5.00mL 3.5.35.00mL 100mL 3.1


1mL 4 1.00mg2 30.0g 1 30.0g

4.1

4.2

4.3

10mL

5.1

5.1.1

1g2g 10mL

3.1 10mL
5.1.2

1g2g 100mL 3.2

50mL3.42mL 100mL 3.330mL


3.1
10mL 0.45m
5.2

C18 2504.6mm10m
204nm245nm

280nm 310nm
+=60+40
1.3mL/min
5.3

3.5.40.001.002.005.00mL 10mL

3.1 5L

5.4

5L

V
m

g/g
mg/L
VmL
mg

221

-/

1g 2
2

0.05

0.4

0.03

0.035

0.002

0.002

0.004

g/g

100

800

60

70

222

10

10.1

10.2

10.3

10mL

11
11.1

11.2

C18 250mm4.6mm10m
254nm 280nm

310nm
+=80+20
45
0.6mL/min
11.3

01.02.05.0mL 3.5.4 10mL 3.1

5L

11.4

5L

12

13

3
1(2.68min)

2(3.62min)

5(5.58min)

3(4.22min)

6(6.54min)

223

4(4.81min)

7(9.74min)


14

/GC-MS 7

C18 GC-MS-SIM
15

15.1

15.2

15.3

15.4

HFBA

15.5

7 TPMTE2

E3E1DES7 4
OH
CH3

COCH3

H
H

CH3

Testosterone(T)

OH

CH3

HO

O
Progesterone(P)

Methylteseosterone(M T)

OH
CH3

CH3
OH

H
H

HO

OH

Estradial(E2)

O
HO
OH

HO
Estriol(E3)

Estrone(E1)

Diethylstilbestrol(DES)

15.6
15.6.1

[1g/L]

0.100g15.3 100mL

15.6.2

[1g/L]

0.100g15.3 100mL
15.6.3

[1g/L] 0.100g15.3

100mL
15.6.4

[10mg/L]15.6.15.00mL

15.6.25.00mL 15.6.35.00mL 500mL


15.3
15.6.5

[1g/L]15.6.410.0mL 100mL

15.3
224

16
16.1

16.2

DB-5MS 30m0.25mm0.25m

16.3

16.4

16.5

C18

16.6

17
17.1

1.0g 15.12mL 3

15.21mL 15.20.5mL
15.215.30.5mL 3.5mL
C18 [15.33mL 5mL+1+73mL
]+1+43mL 15.27mL
35HFBA
15.440L 60 65min 1.0L
17.2

1.0mL/min
270280 1202min

20/min 2002min 3/min 2805min


1.0L
EI 70eV
10min
SIM
17.3

15.6.51.0mL

HFBA
15.440L 60 65min 1.0L

18

18.1 7 5
18.2

225

5
1

DES2

MT3

T4 E25

E36 E17

7
226

3 7

min

m/z

DES

10.87

341

447 660

MT

14.17

369

465 480

17.96

320

467 680

E2

18.31

409

451 664

E3

18.69

E1

19.24

409

422 466

22.50

370

425 510

449

663

19
19.1

<30%
19.2

227


UV filters

--

-4 -5
-3p-4-PABA

-- 15

1
1

ng

ng

0.02

0.07

-4 -5

0.03

10

0.10

0.02

0.07

-3

0.03

10

0.10

p-

0.03

10

0.10

4-

2.5

0.025

0.08

PABA

0.03

10

0.10

12

0.12

40

0.40

0.05

17

0.17

10

0.03

10

0.10

11

20

0.20

67

0.67

12

20

0.20

67

0.67

13

0.02

0.07

14

0.05

17

0.17

15

0.05

17

0.17

228

3.1
3.2
3.3 [HClO47072]
3.4 3.13.23.3=2504503000.2
3.5 2
100mL 2
3.6 1.00mL 100mL
3.4 100mL
2

[1]

g/L mg/L

[2]

0.300

3.4

30

-4 -5

1.000

3.4

10

100

0.300

3.4

30

-3

1.000

3.4

10

100

p-

1.000

3.4

10

100

4-

0.600

3.4

60

PABA

1.000

3.4

10

100

3.000

3.2

30

300

1.450

3.2

14.5

100[3]

10

1.000

3.2

10

100

11

5.000

3.2

50

500

12

5.000

3.2

50

500

13

0.500

3.2

50

14

1.000

3.2

10

100

15

1.000

3.2

10

100

[1] 3 [2] NaOH


[3]

4
4.1
4.2
4.3 10L
4.4 0.45m

5
5.1
229

C18 250mm4.6mm5m
311nm
1.0mL/min

A3.1 0.45m
B3.2
0.45m
C+3.3
300+0.2 0.45m
3
3

min

A%

B%

C%

0.00
13.00
14.00
20.00
22.00

25
25
45
45
25

45
45
50
50
45

30
30
5
5
30

5.2
5.2.1 0.25g 25mL
3.4
20min30min 1.00mL
3.4 10.0mL 0.45m
5.2.2 0.25g 25mL
3.2
20min30min 1.00mL
3.2 10.0mL 0.45m
5.3
3.600.201.005.0010.0mL 10mL
3.4 10L

5.4
10L

V10-4
m
%
mg/L
VmL
mg
=

230

12-4 -534-35p-
64-7PABA 8910
12 12 111213
14-15-

-4 -5
-3p-4-PABA

-- 15

10
10.1 12504503000.2
10.2 2450500500.5

11
11.1
11.2
231

11.3 10L
11.4 0.45m

12
12.1
C18 250mm4.6mm5m
110.1 210.2

1.0mL/min
311nm
12.2

12.3

12.4
12.4.1 110.4 1 12
12.4.2 210.5 1 3
12.4.3 10L

13

14

110.1

12-4 -534-35p-
64-7PABA 8910
12 12 1112

232

210.2

12-3-

233


Preservatives

2--2--13- 12

2--2--13- 12
1

2--2--13- 12

1g 1
1
2

2--2-

4- 4- 4- 4- 4-

4-

-1,3-

(g)

0.002

0.15

0.002

0.1

0.1

0.002

0.05

0.005

0.005

0.005

0.015

0.015

(g)

0.007

0.5

0.007

0.34

0.34

0.007

0.17

0.017

0.017

0.017

0.05

0.05

300

200

200

100

10

10

10

30

30

13

1000

13

667

667

13

340

34

34

34

100

100

(g/g)

(g/g)

3
3.1
3.2
3.3
3.4
3.5 3.1
100mL 2

2
2--2-

(g/L)

(mg/L)

4- 4- 4- 4- 4-

4-

-1,3-

25.0

25.0

25.0

25.0

10.0

1.0

10.0

1.0

1.0

1.0

2.5

2.5

250

250

250

250

100

10

100

10

10

10

25

25

500

500

500

500

250

20

250

20

20

20

50

50

1000

1000

1000

1000

500

50

500

50

50

50

100

100

234

4
4.1
4.2
4.3
4.4 pH
4.5 0.45m
5
5.1
1.00g
3.1 10mL 15min 0.45m

5.2
C18 250mm4.6mm10m
0.05mol/L =503515
0.002mol/L pH 3.5
1.5mL/min

280nm
254nm
5.3
3.55L

5.4
5.15L

V
m
g/g
mg/L
VmL
mg

235

254nm
12.11022--2--1,3-2.58732.933
43.67254.29664-4.919
75.548 8
4-7.84394-12.745104-14.48311
4-26.737124-28.816

280nm

12.11022--2--1,3-2.58732.9334
3.67254.29664-4.91975.548847.84394-12.745104-14.48311
4-26.737124-28.816

236


Oxidative Hair Dyes
1

p- 8

9511 p- 8

0.5g 1
1
2

p-

m-

o-

p- 2,5- p-

0.08

0.015

0.02

0.03

0.025

0.05

0.025

0.05

0.27

0.05

0.067

0.10

0.083

0.17

0.083

0.17

g/g

800

150

200

300

250

500

250

500

g/g

2700

500

670

1000

830

1700

830

1700

3
3.1 [CH3CH2OH=95]
3.2 1+13.1
3.3
3.4 [20H4PO3=1.83g/mL]
3.5
3.6
3.7 [5g/L] p- 8 0.5g
0.1g 3.6
0.1g 953.1
100mL 25- p-

4
4.1
4.2
4.3 pH
4.4 25mL
4.5 0.45m
5
5.1
C18 2504.6mm10m
237

10mL 980mL pH 7.7 1L


950mL 3.550mL 5
2.0mL/min
20
280nm
5.2
0.5g 1 1.0mL 25mL 1+1
3.2 25mL 15min 0.45m
5.3
3.71.00mL2.50mL5.00mL 3 100mL
953.1 50125250mg/L
5L

5.4
5.25L

V
m
g/g
mg/L
VmL
mg
=

1p-3.399min2p-3.881min34.884min4 25-6.080min
5m-5.405min6o-8.070min78.715min8p-9.848min

238


Chlormethine
1

0.3ng
1.0ng 5g 0.3g/g 1g/g

3
3.1 99.999%

3.2 99.999%

3.3 5
3.4
3.5
3.6 1mol/L
201.19g/mL8.3mL 100mL
3.7 2mol/L 8g 100mL
3.8
3.9 [CH3NCH2Cl2=1g/L][CH3NCH2Cl2HCl]
0.1234g 100mL
3.10 [CH3NCH2Cl2=10mg/L]3.9
1.00mL 100mL
4
4.1
4.2 10L
4.3 DB-225 0.25mm 30m
5
5.1
5g 25mL 5mL3.6 pH
2 3.45mL 30s
3.73.8 50mg3.4
5mL 30s

5mL3.5

5.2
170C 200C50C1min8/min 160C
10min

239

60mL/min 50mL/min 500mL/min


150
5.3
1L

VA1

mA0
g/g
mg/L
A1
A0
VmL
mg
7

(1)

240


Cantharidin
1

0.6ng 2.0ng
5g 0.6g/g 2g/g
2

3
3.1 99.999%

3.2 99.999%

3.3 5
3.4
3.5
3.6 [C10H12O4=1g/L] 0.1000g
100mL
3.7 [C10H12O4=10mg/L]3.61.00mL
100mL
4
4.1
4.2 10L
4.3 DB-5 0.25mm 30m
5
5.1
5g 25mL 5mL 5mL 30s

5mL
3.5
5.2
230C 250C60C1min
10/min 230C
10min
60mL/min 50mL/min 500mL/min
150
5.3
1L 3.7

241

VA1

mA0
g/g
mg/L
A1
A0
VmL
mg
7

(1)

242

-
-Hydroxy Acid

-
1

5 -
- 1g
1
1 -

0.1

0.35

0.2

0.4

0.25

0.33

1.17

0.67

1.33

0.83

g/g

200

700

400

800

500

g/g

660

2340

1340

2660

1660

3
3.1
3.2
3.3 -- 100mL
2
2 -
-

g/L

5.0

8.0

20.0

40.0

20.0

100

160

400

800

400

250

400

1000

2000

1000

500

800

2000

4000

2000

mg/L

4
4.1
4.2
4.3
4.4
4.5 pH

243

5
5.1
1g 10mL 10mL
20min 10000rpm 15min 0.45m

5.2
C8 250mm4.6mm10m
0.1mol/L pH 2.45
0.8mL/min

214nm
5.3
6 - 5L
-
5.4
5.15L
-
6

V
m
--g/g
-mg/L
VmL
mg
-=

123 1456 2

244

5 -
- 0.5g
3
3 -
8

ng

0.94

1.1

0.83

0.90

1.7

ng

20

8.0

9.0

8.5

10

g/g

3.8

4.4

3.3

3.6

6.8

g/g

80

32

36

34

40

9
9.1
9.2
9.3
9.4 -

5 - 100mL
4

4 -
-

mg/L

1000

1000

1000

1000

2000

2.00

0.45

0.50

0.60

1.00

5.00

5.00

4.00

5.00

4.00

10.0

10.0

10.0

10.0

10.0

30.0

40.0

40.0

40.0

60.0

70.0

50.0

80.0

70.0

120

mg/L

10
10.1
10.2
10.3
10.4
11
11.1
0.5g 50mL
20min 19000rpm 10min 0.25m
,
11.2
ICE-AS69250mm AMMS-ICE
245

0.4mmol/L
5mmol/L
1.0mL/min
1.5mL/min
5psi

25L

11.3
5 - 0.5mL~1.0mL
-

11.4
11.10.5mL~1.0mL
-
12

V
m
--g/g
-mg/L
VmL
mg
-=

13

1.08 050802 #12 [modified by A


S

ECD_
3

2
0.75
1

0.50

4
5

0.25

0.14
3.21

min
4.00

5.00

6.00

7.00

8.00

9.00

10.00

11.00

12.00

1 6.0mg/L2 5.0mg/L3 5.0mg/L4 5.0mg/L5 5.0mg/L

14

NN- 5 -

246

13.13

15
15.1 BSTFA
15.2 NN-DMF
15.3 -[-=10g/L]
500mg 50mL DMF15.2
16
16.1
16.2
16.3 2mL
16.4 50mL
16.5 10mL
17
17.1
CP-Sil8CB30m0.32mm0.25m
601min 10/min 3105min 330
50mL/min 35mL/min 350mL/min
150
17.2
0.1g~0.5g 10mL DMF15.2 10mL
20min 0.45m 50L 2mL BSTFA
15.1100L80 20min
17.3
50.0mg/L100mg/L300mg/L1000mg/L
1L
17.4
1L

18

V
m
--g/g
-mg/L
VmL
mg
-=

247

19

17.7732(7.937)3(13.478)4(15.278)5(17.177)

248


Antidangdruff agents

955

0.5g 1
1
2

ng

1.0

1.5

2.0

4.5

ng

3.3

5.0

6.7

15.0

g/g

20.0

30.0

40.0

90.0

g/g

66.7

100

133

300

3
3.1
3.2
3.3
3.4
3.5

3.6 85mL 955 1


100mL 955
2 955

mg/L

500

500

1000

1000

50

50

100

100

100

100

200

200

200

200

400

400

400

400

800

800

500

500

1000

1000

mg/L

249

4
4.1
4.2
4.3 pH
4.4 0.45m

5
5.1

0.5g 50mL 955 1


40min 0.45m
5.2
C18 150mm 4.6mm5m
++0.01mol/L
0.5mmol/L pH 4.050+10+40
1.0mL/min

230nm
300nm
5.3
3.65L

5.4
5.15L

V
m
g/g
mg/L
VmL
mg

250

230nm

11.517233.08045.454
59.897

251


Antibiotics and Metronidazole

268nm
1g 1
1
2

ng

50

50

ng

150

150

3.3

3.3

3.3

3.3

3.3

g/g

50

50

g/g

150

150

3.3

3.3

3.3

3.3

3.3

3
3.1
3.2
3.3
3.4 0.1mol/L20=1.19g/mL8.3mL 1L
3.5
0.1000g3.13.4
100mL 1.00g/L

4
4.1
4.2
4.3
5
5.1
1g 10mL 3.1+3.2=1+1
20min30min 0.45m
252

5.2

C18 250mm4.6mm I.D.5m


268nm
0.01mol/L pH 2.0++=67+11+22
HPLC
0.45m
0.8mL/min

5.3
3.5 10mL
0.45m 10L

5.4
10L 5.1

V
m
g/g
mg/L
VmL
mg

1234
567

253

D2 D3
vitamin D2vitamin D3
1

D2 D3
D2 D3

D2 D3 265nm
D2 D3
0.5g 1
1
2

D2

D3

ng

0.58

0.32

ng

g/g

2.6

1.3

g/g

3
3.1
3.2
3.3
D2 D3 0.1000g 100mL
3.1
4
4.1
4.2
4.3
4.4
5
5.1
0.5g 10mL
20min 0.45m
5.2
C18 250mm4.6mm5m
265nm
9010HPLC 0.45m
1.0mL/min

5.3
254

5.3.1 D2 D3
D2 D3 263nm
95 1 D2

1 1cm 460 1 D3 1 1cm 485


/
100A
P

C1 1cmL
P D2D3
A D2D3
C D2D3
Lcm

1 1cm D2D3
5.3.2 D2 D3 3.3 1.00mL
3.1 10.0mL 100.0mg/L D2D3
2 50.0mg/L
20.0mg/L10.0mg/L2.00mg/L0.50mg/L
5.3.3 5L HPLC

5.4
5L HPLC

V
M
D2D3 D2D3 g/g
D2D3 mg/L
VmL
mg

D2D3

30

10.693 - VIT D3

9.962 - VIT D2

VWD1 A, Wavelength=265 nm (VITD6213\1S-ST3.D)


mAU

25

20

15

10

9.555

2.530

5
1.586

0
0

255

10

12

14

1 D22 D3

16

min


Dissolvable zinc salt
1

8.210-3g 2.710-2g 1g 8.210-3g/g


2.710-2g/g
2

3
3.1 201.42g/mL
3.2 1.5+998.53.11.5mL 1000mL
3.3 [Zn1.00g/L] 99.9 1.000g 20mL
3.1 1L 1.00mL 1.00mg
3.4 [Zn20.0mg/L]3.32.00mL 100mL
3.1 100mL

1+1 4h
4.1
4.2
4.3
4.4 10mL25mL
4

5
5.1
1.00g2.00g 25mL 10mL
20min 5000rpm 40min 2.00mL~5.00mL 3.2
10.0mL
5.2
3.40.000.501.002.003.005.00mL 100mL
3.2
5.3
5.3.1 213.9nm
3.4

5.3.2

256

Zn

10V

V2

m
V1
Zng/g
1mg/L
0mg/L
VmL
V1mL
V2mL
mg

97.0%~98.5
1.26%

257

UVA
Test in vitro of protection against UVA
1

UVA320nm~400nm
UVA

3M SPF C
UVA/UVB R
C UVAUVB290nm~400nm 90 UVA
nm

90% =

400

290

290

A( )d / A( )d

A
UVA/UVB R

R=

400

400

320

290

A( )d / A( )d

3
3.1 SPF Optometrics Group SPF-290 Analyzer
C
3.2 3M PMMA 55cm,Europlast
3.3
3.4
3.5
SPF15 C366nmC 365nm367nm
4
4.1
3M

1.8mg/cm2~2.2mg/cm2 PMMA
3M
4.2
3M
258

4.1 20~3040~60
20min SPF 4
5
5.1

5.2
5.2.1
5.2.2 4
C 1
5.2.3 C 2nm

6.1
6.2 C
6.3 C
6.4
C370nm

259

Methods of Microbiological Test


General Principles
1

2
2.1
2.2
2.3
2.4 250mL
2.5
2.6
2.7 1mL10mL
2.8
2.9
3
3.1

8.5g

1000mL
90mL103.43kPa121 15 lb20min

3.2 SCDLP

17g

3g

5g

2.5g

2.5g

1g
80
7g

1000mL
pH
7.27.3 103.43kPa121 15 lb20min
80 25

3.3
3.4 80
4
4.1
260

10g 10mL 20g

4.2

4.3

4.4

4.5

4.6
5
5.1
5.1.1 10mL 90mL 10mL
10 5mL 45mL 110
5.1.2 10mL 5mL 10mL
80 4044 10min 75mL 4044

4044 110
5.2
5.2.1 10g 90mL
15min 1:10
5.2.2 10g 10mL
10mL 80 70mL 4044
110
5.3
10g 90mL
110
10g 90mL
1min2min 10g 10mL
10mL 8070mL 3min5min

261


Aerobic Bacterial Count
1

Aerobic bacterial count


pH 1g1mL

3
3.1 250mL
3.2 200mL
3.3 pH pH
3.4
3.5 15150mm
3.6 9cm
3.7 10mL1mL
3.8
3.9 361
3.10
4
4.1 3.1
4.2 80
4.2.1
20g

3g

5g

15g

1g
80
7g

1000mL
4.2.2 80
 80 pH 7.1
7.4103.43kPa121 15 lb20min
4.3 0.52,3,5-triphenyl terazolium chlorideTTC
TTC
0.5g
262


100mL
103.43kPa121 15 lb20min 4

5
5.1 110 2mL 1mL
1mL 9mL
1100 2mL 1mL
11000110000 1
5.2 4550 80
15mL 36
1 48h2h 15mL
80 361 48h2h

5.3 100mL 80 1mL


0.5 TTC

5 10

7
7.1 30 300
1 1

7.2 30 300 
2 2
1 2 3
7.3 300
1 4
7.4 30
1 5

7.5 30 300 300


30
30 300
1 6

7.6 g mL 10CFU
7.7 10 100

10 1

263

10-1
10-2
10-3

1
2
3
4
5
6
7

1365
2760
2890

27

164
295
271
4650
11
305
0

20
46
60
513
5
12
0

CFU/mL CFU/g CFU/mL CFU/g


16400
38000
27100
513000
270
30500
10

1.6
2.2

*CFU

264

16000 1.6104
38000 3.8104
27000 2.7104
510000 5.1105
270 2.7102
31000 3.1104


Fecal Coliforms
1

Fecal coliforms 44.5


0.5 24h48h

3
3.1 440.5
3.2
3.3
3.4
3.5
3.6
3.7 250mL
3.8 15150mm
3.9
3.10 pH pH
3.11
3.12 10mL1mL
3.13 90mm
4
4.1

40g

10g

10g
0.4
5mL

2g
80
14g

1000mL
80

pH 7.4 0.4

68.95kPa115 10 lb20min
4.2 EMB

10g
265


10g

2g

20g
2
20mL
0.5
13mL

1000mL
900mL
1000mL pH 7.27.4103.43kPa
121 15 lb15min 60

4.3

20g

5g

1000mL
pH 7.07.2103.43kPa121 15
lb15min
4.4
5g 75mL 25mL
440.5 24h2h
0.3mL0.5mL

4.5
4.5.1
4.5.1.1

1g
95
20mL
1
80mL

4.5.1.2

1g

2g

300mL

300mL
4.5.1.3 95
4.5.1.4
1

0.25g
95
10mL

90mL

2 10g 95 100mL
10mL 5 90mL 10mL
90mL
266

4.5.2
4.5.2.1 1min
4.5.2.2 1min
4.5.2.3 95 30s
10s
4.5.2.4 1min
4.5.3

1:10 10s
5
5.1 10mL 110 10mL 44
0.5 24h48h
5.2 361 18h24h
12 440.5 24h2h

5.3
5.4 0.5mL

267


Pseudomonas Aeruginosa
1

Pseudomonas aeruginosa
421

3
3.1 421361
3.2 250mL
3.3 15150mm
3.4 90mm
3.5 10mL1mL
3.6
3.7
3.8
3.9
3.10
4
4.1 SCDLP
3.2
4.2

3g

10g

5g

0.3g

20g

1000mL
pH 7.47.668.95kPa
115 10 lb20min
4.3

10.0g

5.0g

1.39g
268


0.73g
0.5g
MgSO4.7H2O

0.012g

20g

1000mL
pH 7.2
103.43kPa121 15 lb20min
4.4

20g

1.4g

10g

18g

10g

1000mL
pH 7.4
68.95kPa115 10 lb20min

4.5

3g

5g

120g

1000mL
20min pH 7.4
68.95kPa115 10 lb20min
4.6

10g

3g

2g

0.5g

1000mL
pH 7.2
68.95kPa115
10 lb20min
4.7

10g

3g

5g

15g

1000mL
pH 7.27.4
103.43kPa121 10 lb20min
5
5.1 1:10 10mL 90mL SCDLP 361
269

18h24h

5.2
361 18h24h

361 24h2h

5.3

5.4
1
15s30s

5.5 2 3 36
1 24h2h 3mL5mL
1mol/L 1mL


5.6
361 24h2h

5.7
361 24h2h 10min30min

5.8 42
421 24h48h

42

270


Staphylococcus Aureus
1

Staphylococcus aureus

3
3.1
3.2 361
3.3
3.4 1mL10mL
3.5 15150mm
3.6
3.7
4
4.1 SCDLP
3.2
4.2 7.5

10g

3g

75g

1000mL
pH 7.4103.43kPa121 15 lb15min

4.3 Baird Parker

10g

5g

1g

10g

12g
5g
LiCl6H2 O
271

20g
950mL
pH7.00.2
30 50mL 1 10mL

251 pH
95mL103.43kPa121 15 lb 15min 95mL
50 5mL
48h2h
4.4

100mL

10mL
50

4.5

10g

5g

10g

5g
0.2
12mL

1000mL
pH7.4
68.95kPa115 10 lb20min
4.6
3.8103.43kPa121 15 lb30min 1
4 2000rpm3000rpm 3min5min

5
5.1 110 90mL SCDLP 361
24h2h
7.5
5.2 12 Baird Parker
361 24h48h
Baird Parker
2mm3mm

36
1 24h2h
5.3
0.5m
1m
5.4
2mm3mm 361 24h2h

272

5.5 1:4 0.5mL 24h2h


0.5mL 3616h

0.5mL 1:4 0.5mL

273


Molds and Yeast Count
1

Determination of molds and yeast count


1g 1mL

282
72h
2

3
3.1 282
3.2
3.3
3.4 250mL
3.5 15150mm
3.6 9cm
3.7 1mL10mL
3.8 200mL
3.9
3.10
4
4.1
3.1
4.2
5g

10g

1g
0.5g
7H2O

20g
1/3000
100mL

1000mL

100mg

103.43kPa121 15 lb20min
274

1000mL 30mg
5
5.1
6.1
5.2 110110011000 1mL 2
451
281 72h2h
48h2h
5.3
5 50
g mL

5.4 g mL CFU/gmL

275

Methods of Safety and Efficacy


Evaluation in Human


General principles

2
2.1
2.2

2.3

2.4

2.5

Sun Protection FactorSPFSPF

Protection Factor of UVAPFA

276


Human Skin Patch Test

GB17149.1-1997
GB17149.2-1997

4.1

4.2

4.3

/1%
/5%
10%

5.1

18~60

5.2

5.2.1

5.2.2

5.2.3

5.2.4

5.2.5

5.2.6

5.2.7

5.2.8

277

5.2.9

5.2.10

5.2.11

5.2.12

5.2.13

6
6.1

6.2

6.2.1

30

6.2.2

0.020g0.025g

0.020mL0.025mL

24h
6.2.3

30min

24h48h1
1

6.3
6.3.1

30

6.3.2

55cm

6.3.3 0.3g0.5gmL27

6.3.4

6.3.5

278

7
7.1

3015

2225
133
7.2 30155
22213311

279


Safety Evaluation of Using Tests of Cosmetics on Human Body

4.1

18~60

4.2

4.2.1

4.2.2

4.2.3

4.2.4

4.2.5

4.2.6

4.2.7

4.2.8

4.2.9

4.2.10

4.2.11

4.2.12

4.2.13

280

1
1

6
6.1

30

11
4
6.2

30

1
1
4
6.3

30

1
1
4
6.4

30

3012

2211133
303
312221
33

281


Tests in vivo of UV Protection Efficacy of Cosmetic Sunscreens
1

SPFSPF
PFA
3

282

SPF

SPF
SPF

1FDA
Testing ProcedureFederal Register21 CFR. Part352. 70-731999
2SPFCOLIPACTFAJCIA
International Sun Protection FactorSPFTest Method2006

3.1

UVC200nm290nm
UVB290nm320nm
UVA320nm400nm

3.2

Minimal erythema doseMED

J/m2
3.3 Sun protection factorSPF
MEDMEDSPF

SPF

MED
MED

SPF

4.1

4.1.1

4.1.2

4.1.3 1290
nm400nm280nm400nm
%RCEERelative Cumulative Erythemal
Effectiveness%RCEE1

283

%RCEE

nm

%RCEE

<290

<1.0

290-300

1.0

8.0

290-310

49.0

65.0

290-320

85.0

90.0

290-330

91.5

95.5

290-340

94.0

97.0

290-400

99.9

100.0

4.1.4

4.2

4.2.1

1860

4.2.2

4.2.3 IIIIII

4.2.4

4.2.5

4.2.6
4.3

1025
SPF

4.4 MED
4.4.1
4.4.2

30cm2

4.4.3 2mg/cm2
15
4.4.4 MED24
516-24
MED
4.4.5
4.4.5.1

SPFMED
MED4.4.4MED

MED
4.4.5.2 MED
4.4.4MED5
SPFSPF15
25%SPF>1512%
4.4.5.3

MEDSPFSPF

15SPFSPF>15SPFP2

284

P3MED4.4.4
4.5

55

4.6

SPF
SPF
MED

SPF

MED

SPFSPF
95%95%CI
17%1095%CI8.311.7
25
5

2
2

SPF

01
02
03
04
05
06
07
08
09
10
X
SD
95%CI

285

SPF

SPF

SPF
1

SPF

8%SPF4.471.297

3 SPFSPF4.471.297SPF
95%SPF4
4

A
Homosalate

8.00

Lanolin

5.00

Stearic acid

4.00

White petrolatum

2.50

Propylparaben

0.05

B
Purified water

74.30

1,2-Propylene glycol

5.00

Triethanolamine

1.00

Methylparaben

0.10

EDTADisodium EDTA

0.05

AB7282
AB1530
100g
SPFP2P3
SPFP2P3SPF
International Sun Protection FactorSPFTest Method2006

286

SPF

FDATesting Procedure

Federal Register/Vol 64No98/1999

2332

4.1

SPF40min

SPF
4.1.1

15min

4.1.2

20min

4.1.3

20min

4.1.4

20min

4.1.5

4.1.6

SPF

4.2

SPFvery water resistantSPF

80minSPF
4.2.1

15min

4.2.2

20min

4.2.3

20min

4.2.4

20min

4.2.5

20min

4.2.6

20min

287

4.2.7

20min

4.2.8

20min

4.2.9

4.2.10

SPF

SPFSPF

50%

288

PFA

UVA

PFAPAPA

UVA

2003

3.1

UVC200nm290nm
UVB290nm320nm
UVA320nm400nm

3.2 Minimal persistent pigment darkening doseMPPD2


4
MPPD24

3.3

UVAProtection factor of UVAPFA

MPPDMPPDPFA

PFA

MPPD
MPPD

4.1

4.1.1 1860
4.1.2

4.1.3

4.1.4

4.1.5

4.2

1020

289

4.3

2mg/cm22L/cm2

4.4

30cm2

4.5

15min

4.6

4.6.1

UVA

4.6.2 320nm400
nm
4.6.3

MPPD
4.7

0.5cm28mm

4.8

25%PFA

4.9

PFA

MPPDp

PFA

MPPDu

MPPDpMPPDMPPDuMPPD
PFAPFA
10%
20

UVA
UVAPFAUVAPA

Protection of UVAPFSPFPFA
PA
PFA2

UVA

PFA23

PA

PFA47

PA

PFA88

PA

290


1
1

A
Purified water

57.13

Dipropylene glycol

5.00

Phenoxyethanol

0.30

Potassium hydroxide

0.12

EDTATrisodium edetate

0.05

B
-2-Glyceryl tri-2-ethylhexanoate

15.00

/Cetearyl alcohol

5.00

Butyl methoxydibenzoylmethane

5.00

Petrolatum

3.00

Stearic acid

3.00

Ethylhexyl methoxycinnamate

3.00

Glyceryl monostearateselfmulsifying

3.00

Methylparaben

0.20

Ethylparaben

0.20

A70B
70BA
PFA3.751.01

291

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