FIRST-LINE ANTITUBERCULAR MEDICATIONS ISONIAZID

o Peripheral neuritis o Hepatic enzyme elevation o Hepatitis o Hypersensitivity Pyridoxine as prophylaxis for neuritis

RIFAMPIN
o Hepatitis o Febrile reaction o Purpura(rare) o Nausea o Vomiting Orange urine & other body secretions

STREPTOMYCIN
o

8th cranial nerve damage (may lead to deafness)

o Nephrotoxicity

PYRAZINAMIDE
o Hyperuricemia o Hepatotoxicity o Skin rash

o Arthralgias o GI distress

ETHAMBUTOL
o Optic neuritis (may lead to blindness) o Skin rash Monitor visual acuity, color discrimination