Medicine Side Effects

Aminoglycosides Ototoxicity
Nephrotoxicity
Tetracyclines Tooth discoloration
Photosensitivity
Esophageal irritation
Intracranial hypertension
Bisphosphonates Esophageal irritation
Hypophosphatemia
Osteonecrosis of the jaw
Atypical femoral fracture
Cyclophosphamide Hemorrhagic cystitis
Ifosfamide
PDE5 inhibitors Hypotension
Nasal congestion
Headache
Dizziness
Tachycardia
Statins Rhabdomyolysis
Diabetes
Elevated liver enzymes
Lamotrigine Skin rash, sometimes SJS/TEN
Isoniazid Pyridoxine deficiency
Peripheral neuropathy
Hepatotoxicity
Amiodarone Blue-gray skin discoloration
Pulmonary toxicity
Thyroid abnormalities
 Photosensitivity
Corneal microdeposits
Vancomycin Ototoxicity
Nephrotoxicity
Hepatotoxicity
Blood disorders – thrombocytopenia
Red man syndrome
Quinine Conchonism
Deafness
Blindness
QT prolongation
Fluoroquinolones Tendon rupture
QT prolongation
Lowering seizure threshold
Corticosteroids Steroid-induced diabetes
Osteoporosis
Mood / behavioral changes
Hypertension, hypokalemia
Edema
Immunosuppression
Opioids Constipation
Euphoria
Respiratory depression
Itch
Pupillary constriction
Metformin Weight loss
Lactic acidosis
Vitamin B12 deficiency
Gastrointestinal upset
Trimethoprim Gastrointestinal upset
Hyperkalemia
Elevated creatinine levels
Megaloblastic anemia
Phenytoin Gingival enlargement
Hirsutism
Osteomalacia
Skin coarsening / acne
Nystagmus / ataxia
Purple glove syndrome
ACE inhibitors Persistent, dry cough
Hyperkalemia
Hypotension
Renal failure
Aspirin Bleeding
Stomach ulcers
Reye syndrome (under 16s)
Tinnitus (high doses)
Iron supplements Black stools
Bismuth subgallate Black tongue, black stools
Amphotericin B ‘Shake and bake’ reaction
Hypokalemia
Myocarditis
Hepatotoxicity
Kidney damage
Lithium Hypothyroidism
Diabetes type 2
Kidney damage
 Weight gain
Myoclonus
Clofazimine Hyperglycemia
Brown-pink skin discoloration
Skin dryness, rash
Ethambutol Red-green color blindness
Optic neuritis
Hepatotoxicity
Peripheral neuropathy
Hyperuricemia
Clozapine Agranulocytosis
Myocarditis
Hypersalivation
CNS effects
Urinary incontinence
GI hypomotility
Bone marrow suppression
SSRIs Weight disturbance
Gastrointestinal upset
QT prolongation
Hyponatremia
Bone fractures
Serotonin syndrome
Lower seizure threshold
Antimuscarinics Tachycardia
Dry mouth
Blurred vision
Urinary retention
Constipation
Drowsiness
Beta-2 agonists Tachycardia
Palpitations
Anxiety
Tremors
Muscle cramps
Hypokalemia
Sweating
Insomnia
Agitation
Typical Extrapyramidal side effects
antipsychotics QT prolongation
Sexual dysfunction
Atypical Weight gain
antipsychotics Diabetes type 2
Lipid abnormalities
Extrapyramidal effects
Benzodiazepines Drowsiness, sedation
Respiratory depression
Amnesia
Decreased concentration
NSAIDs Gastrointestinal bleeding
Renal impairment
Fluid retention
Photosensitivity
Beta blockers Bronchospasm
Vivid dreams / nightmares
Cold extremities
Hypoglycemia
Methimazole Agranulocytosis
Calcium channel Constipation
blockers Gingival overgrowth
Ankle swelling
Flushing
Rifampin Hepatotoxicity
Red urine, sweat, tears
Methotrexate Hepatotoxicity
Ulcerative stomatitis
Infections
Pulmonary fibrosis
Irinotecan Extreme diarrhea
Cisplatin Hearing loss
Kidney damage
High risk of vomiting
Flucytosine Bone marrow suppression
Loss of appetite
Psychosis
Renal damage
Macrolides QT prolongation
GI effects
Ototoxicity (high doses)
Cholestatic jaundice
Heparin Bleeding
Warfarin Thrombocytopenia (heparin)
Antiplatelets
Anticoagulants
Levothyroxine Weight loss
Trouble sleeping
Tachycardia
 Anxiety
Difficulty tolerating heat
Palpitations
Thalidomide Phocomelia / limb deformities
Carmustine Pulmonary toxicity
Busulfan
Iron dextran Severe anaphylaxis
Capecitabine Hand-foot syndrome
Tamoxifen Uterine cancer
Pulmonary embolism
Reduced cognition
Irregular periods
Hot flashes
Nitrates Flushing
Headache
Light-headedness
Hypotension
Nitrofurantoin Gastrointestinal upset
Pulmonary fibrosis
Brown discolored urine
Peripheral neuropathy
Elevated liver enzymes
Hemolyticanemia
Thiazolidinediones Anemia
Dizziness, headache
Edema
Bladder cancer
Bone fractures
Hepatotoxicity
Valproate Gastrointestinal upset
Tremor, ataxia, behavioral effects
Increased liver enzymes
Thrombocytopenia
Hair loss
Pancreatitis
Itraconazole Vision disturbances
Heart failure
Skin rash
Hepatotoxicity
Linezolid Thrombocytopenia
Peripheral neuropathy
Serotonin syndrome
Metronidazole Metallic-like taste
Seizures
Thrombophlebitis (IV use)
Dark urine
Peripheral / optic neuropathy
Encephalopathy (high doses)
Disulfiram-reaction (with alcohol)
Loop diuretics Dehydration
Hypotension
Low electrolyte state
Hearing loss / tinnitus (high doses)
Kidney failure (w/ NSAID + ACE inhibitor)
Hyperuricemia
Aldosterone Gynecomastia
antagonists Hyperkalemia
Allopurinol Skin rash, sometimes SJS/TEN
Hypersensitivity reaction
Bone marrow suppression
Colchicine Rhabdomyolysis
Bone marrow suppression
Gastrointestinal upset