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Ch 10: Blood Composition of Blood, Functions of Blood plasma and its proteins: o Makes up 55% of blood volume o Has

s proteins + globulins formed elements o Erythrocytes (Red Blood Cells) Structure: Disc shaped and slightly thicker on perimeter Hemoglobin: Carries O2 + CO2. Has iron Hematocrit: Proportion of total blood volume that are RBC (36%-50%) o Leukocytes Diapedesis: WBC moving in and out of blood vessels Chemotaxis: Can respond to chemicals released by damaged tissues Neutrophils: Most common; phagocytic Eosinophils: Kills parasites, overact during allergies Basophils: Release histamine for inflammation Lymphocytes: B-Cells, T-Cells, Nk Cells B: produce antibodies to attack antigens T: Coordinates immune response; destroys Nk: Detects and destroy abnormal tissue cells Monocytes: fights chronic infections o Platelets: stick to collagen fibers; fibrinogen fibrin that traps RBC Blood Formation (Hematopoeisis) Occurs in Red bone marrow Hemostasis (blood clotting) Platelets stick to collagen fibers to form platelet plug Blood vessel narrows Fibrinogen forms fibrin mesh that traps RBCs Blood Groups/ Blood typing Blood types: o O- universal donor o AB-universal recipients Rh factors: If mom is Rh- but child is Rh+, it can cause hemolytic disease of the newborn Disorders/Diseases anemia and sickle cell anemia: hemoglobin shape is different, causes low # of RBC Leukemia: cancerous leukocytes Hemophilia: sex-linked; uncontrollable bleeding

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