PATHOPHYSIOLOGY

PREDISPOSING FACTORS PRECIPITATING FACTORS -DEFECTS IN THE EGG -ABNORMALITY IN THE UTERUS -AGE <20 AND 40> -ASIAN HERITAGE LOW FOLIC ACID INATAKE LOW CHO INTAKE LOW CALORIE INTAKE

Egg cell fails to change composition

EGGS DONOT HAVE CHROMOSOMAL PROPERTIES

EMPTY EGG FERTILIZED BY A SPERMS

EGG FERTILIZED BY 2 SPERMS

FERTILIZATION OF AB ZYGOTE

(+) pregnancy test

Trophoblastic proliferation faster uterine growth abdominal pain

increase HCG > 100,000 ml/u/ml Hyperemesis gravidanum

enlargement of the ovaries due to thecalotaine cyst

low estrogen
amennorrhe a

increase progesterone
decrease contraction

high chorionic thyrotroponin

hyperthyroidism

increase BMR

Weight loss,tachycardia, diaphoresis

Tolerance to heat anemia

abnormal vaginal bleeding

ovarian at the lower quadrant pain

pallor

pre-eclamptic s/s: -dizziness -headache

(-) Fetal tone

All vesicular chorionic villi formed

Some chorionic villi formed

(+) fetal tone

Profuse bleeding -BP

Some retained trophoblast becomes malignant

Spontaneous abortion

Incomplete implantation

Abnormal high HcG

hyperthyroidism complications Fatigue Weight loss Muscle weakness Increase hearth rate Diaphoresis Anxiety Thyroid enlargement

Persistent gtd

Invasive mole

Chorio carcinioma

PREDISPOSING FACTORS

-DEFECTS IN THE EGG

SWELLING PROTEINURIA HEADACHE CHANGES OF REFLEXES

IMPLANTATION

Trophoblastic maturation