DRUG Generic name: ACETYLCYS TEINE Brand name: FLUIMUCIL

ACTION Mucolytic Activity: Splits links in the muco-proteins contained in the respiratory mucus secretions, decreasing the viscousity of the mucus.

INDICATION Mucolytic adjuvant theraphy for abnormal viscid or inspissated mucus secretionsin acute and chronic disease.

To prevent hepatic injury that may occur after ingestion of a Antidote to potientially acetaminphen hepatotoxic dose of hepatotoxicity.p acetaminophen. rotects livee cells by maintaining cell function and detoxifying acetaminoiphe n metabolites.

CONTRAINDICATION Mucolytic use: Hypersensiti vity to acetylcystein e, use caution and discontinue immediately if bronchospas m occur.

ADVERSE REACTION Mucolytic use: GI: nausea, stomtitis. Hypersensitivity: urticaria. Respiratory: bronchospasm. Other: rhinorrhea. Antidotal use: Dermatologic: rash. GI: nausea, vomiting, other GI symptoms.

NURSING RESPOSIBILITIES Instruct patient to increase oral fluid intake. Instruct patient that he/she may experience these side effects: increased productive cough, nausea, GI upset. Instruct patient to report difficulty breathing or nausea.

DRUG Generic name: CEFUROXIM E Brand name: Zegen

ACTION Bind to bacterial cell wall membrane which causes cell death.

INDICATION Oral use: Pharyngitis, tonsillitis, otitis media, lower respiratory infections, UTIs, uncomplicated gonorrhea, skin and skin Structure infections including impetigo. Parenteral use: Lower respiratory infections, dermatologic infections, UTIs, meningitis, septicemia.

CONTRAINDICATION Allergy to cephalospori ns or penicillins.

ADVERSE REACTION CNS: Headache , dizziness, lethargy, paresthesia.

NURSING RESPOSIBILITIES Assess patient fro infection at the beginning and during the therapy.

Before initiating thepary, GI: N/V, diarrhea, obtain a history to anorexia, determine previous use of pseudomembrano and reaction to us colitis. penicillin or cephalosporins. Person GU: Nephrotoxicity with a negative history of penicillin sensitivity may Hematologic: Bone still have an allergic marrow response. depression. O btain specimens for culture and sensitivity before initiating the therapy. O bserve patient for sings and symptoms of anaphylaxis (rash, pruritus, laryngeal edema, wheezing) Assess patient for renal dysfunction and adjust accordingly.

DRUG Generic name: CHLORPHEN AMINE MALEATE Brand name: ANTAMIN

ACTION Competitively blocks the effects of histamines at H1-receptor sites; has atrophin like, anti-pruritic and sedative effects.

INDICATION Symptomatic relief of symptoms associated with perennial and seasonal allergic rhinitis, vasomotor rhinitis:allergic rhinitis.

CONTRAINDICATION Allergy to antihistamines, narrow-angle glucoma, stenosi peptic ulcer, asthmatic attack, bladder neck obstruction.

ADVERSE REACTION CNS: drowsiness dizziness, disturbed coordination CV: hypotension GI: epigastric distress GU: urinary frequency, dysuria Hematologic: Hemolytic anemia, thrombocytopenia Respiratory: thickening of bronchial secretions

NURSING RESPOSIBILITIES Instruct patient to administer dsrug with food if GI upset occurs. Intruct patient not to crush or chew SR preparations. Arrange for periodic blood tests during prolonge theraphy. Instuct patient to avoid alcohol. Instruct patient not to perform tasks that requires alertness(driving). Instruct patient to report difficulty of breathing, hallucinations, tremors, Loss of coordination unusual bleeding or bruises, visual disturbances.

DRUG Generic name: TRANEXAMI C ACID Brand name: Hemostan

ACTION Forms a reversible complex that displaces plasminogen from fibrin resulting in inhibition of fibrinolysis, it also inhibits the proteolytic activity of plasmin.

INDICATION

CONTRAINDICATION antihemorrhagic Patients and antifibrinolytic predispose for effective d to hemostasis in thrombosis. various Prophylaxis surgical and during clinical cases, in pregnancy traumatic injuries, and before post-tooth delivery. extraction and other dental procedures.

ADVERSE REACTION G I disorders: nausea, vomiting. CNS: anorexia, headache may appear, impaired renal insufficiency, hypotension when IV injection is too rapid.

NURSING RESPOSIBILITIES Dosage modification required in patients with renal impairment. W atch out for any signs of bleeding.

DRUG Generic name: HYDROCORT ISONE Brand name: Solu-cortef

ACTION Decreases inflammation by suppression of migration of polymorphon uclear leukocytes and reversal of increased capillary permeability.

INDICATION Management of adrenocortical insufficiency, relief inflammation of corticosteroidresponsive dermatoses, adjunctive treatment of ulcerative colotis.

CONTRAIN DICATION Serious infections, except septic shock or tuberculosis meningitis, hypersensiti vity, viral, fungal or tubercular skin lesions.

ADVERSE REACTION CNS: insomnia, nervousness GI: increased appetite Derma: hirsutismE n d o : diabetes mellitus R e s p : epistaxis other: cataracts, anthralgia

NURSING RESPONSIBILITIES M onitor any sign of anaphylactic reaction. Assess clients urine, muscle weakness and wasting, weight.

DRUG Generic name: CALCIUM PANTHOTENI C Brand name: MORIAMIN FORTE

ACTION Vitamins and minerals contents are absorbed by the intestine and into the bloodstream which is distributed and consumed by the body or stored in the body.

INDICATION Malnutrition, protein and vitamin deficiencies, anemia, convalescence, restoration and maintenance of body resistance, pregnancy and lactation, adjuvant in the therapy of peptic ulcer and TB.

CONTRAIN DICATION

ADVERSE REACTION

NURSING RESPONSIBILITIES Assess patient for signs of vitamin deficiency before and periodically throughout therapy. Assess nutritional status through 24 h diet recall. Determine frequency of consumption of vit rich foods.

Contraindica hypervitaminosis ted for (large doses). patients with malabsorptio n syndrome.

DRUG Generic name: BUTAMIRATE CITRATE Brand name: SINECOD FORTE

ACTION Act centrally (on brain, and specifically the vagus nerve) or locally (on the respiratory tract) to suppress the cough reflex.

INDICATION

CONTRAIN DICATION Hypersen sitivity to Drug.

ADVERSE REACTION CNS: dizziness. GI: Nausea and vomiting, diarrhea. Skin: rash

NURSING RESPONSIBILITIES Assess cough type and frequency, Monitor the adverse reactions. Assess patients VS. Assess sleep pattern. Teach patient: if cough persist 10 days + fever or chest pain check with Doctor. Dont exceed recommended dose . Drink fluids but not immediately after dose. Advise patient to minimize cough by avoiding irritants (cigarette smoke, fumes, dust) . Instruct patient to cough effectively, sit upright and take several deep breaths before attemting.

Acute cough of any etiology. Pre and Post op cough sodation for surgical procedures and bronchoscopy.

DRUG Generic name: CEFUROXIME Brand name: CEFTIN

ACTION Bactericidal: inhibits synthesis of bacterial cell wall, causing cell death.

INDICATION For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

CONTRAIN DICATION Allergy to cephalospori ns or penicillins Renal failure Lactation. Large doses can cause cerebral irritation and convulsions; nausea, vomiting, diarrhea.

ADVERSE REACTION GI disturbances; erythema multiforme, Stevens-Johnson syndrome, epidermal necrolysis.

NURSING RESPONSIBILITIES Hypersensitivity reactions to cephalosporins, penicillins, and history of allergies, particularly to drugs, before therapy is initiated. Inspect IM and IV injection sites frequently for signs of phlebitis. Report onset of loose stools or diarrhea. Although pseudomembranous colitis. Monitor I&O rates and pattern: Especially important in severely ill patients receiving.

DRUG Generic name: Brand name: LEVOPRONT

ACTION

INDICATION

CONTRAIN DICATION Hypersen sitivity, the excess rate, expresse d violations of the liver.

ADVERSE REACTION It is an antitussive drug, it can cause dizziness, somnolence, nausea, vomiting, heartburn,diarrhe a, abdominal discomfort, faintness.

NURSING RESPONSIBILITIES Instruct patient not to perform tasks that require alertness.

The medication with drug Levopront yet to materialize .

Dry unproducti ve cough with pharyngitis, , influenza, pneumonia, bronchial asthma, emphysema lungs.

DRUG Generic name: FLUIMUCIL

ACTION

INDICATION Acute and chronic respiration tract infection with abundant mucus secretion.

CONTRAIN DICATION drug sensitivity Phenylketon uric s

ADVERSE REACTION increased incidence of bronchospas m GI: - nausea - vomiting - stomatitis

NURSING RESPONSIBILITIES Use nonreactive plastic, glass or stainless steel for administration. May administer via face mask, face tent, oxygen tent or by positive pressure apparatus. Administer with compressed air for nebulization. Have suction availabl for emoval of increased secretions.

Reduce the viscosity of purulent and nonpurulent Brand name: secretions and facilitates their ZAMBON removal by splitting disulfide bonds. Action increases with increasing pH. Also reduces liver injury due to acetaminophen over dosage by maintaining or restoring glutathione levels or by acting as an alternate substrate for the reactive metabolite of acetaminophe.

 DRUG Generic name: ACETYLCYST EINE Brand name: ACETADOTE, MUCOMYST

ACTION Mucolytic that reduces the viscosity of pulmonary secretions by splitting disulfide linkages between mucoprotein molecular complexes. Also, restores liver stores of glutathione to treat acetaminoph en toxicity.

INDICATION Adjunct therapy for abnormal viscid or thickened mucous secretions in patients with pneumonia, bronchitis, bronchiectasis, primary amyloidosis of the lung, tuberculosis, cystic fibrosis, emphysema, atelectasis, pulmonary complications of thoracic surgery, or CV surgery

CONTRAINDIC ATION Hypersensitive to drug. Use cautiously in elderly or debilitated patients with severe respiratory insufficiency. Use I.V. formulation cautiously in patients with asthma or a history of bronchospasm. Acetadote is contraindicated in patients with previous anaphylactoid reactions to acetylcysteine.

ADVERSE REACTION Nausea, vomiting, dizziness, flushing, stomach upset, cough, or increased sweating may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

NURSING RESPONSIBILITIES Assess patients history of underlying condition, cough: type, frequency, character. Assess patient respiration & pulmonary secretions, exercise caution on patients with respiratory insufficiency & history of bronchospasm. Instruct patient to follow directions exactly. Explain importance of using drug as directed. Teach patient how to use & clean nebulizer.

DRUG Generic name: CETRIZINE

ACTION

INDICATION Treatment of chronic: idiophatic urticaria, pruritis, eczema, dermatitis, perennial allergic rhinitis and allergic conjunctivitis.

CONTRAINDIC ATION

ADVERSE REACTION

NURSING RESPONSIBILITIES Assess for respiratory status and increase bronchial secretions, wheezing. Instruct patient to use medication as directed. Teach all aspects of medication. Instruct patient to take 1 hour before or 2 hours after a meal to facilitate absorption.

long-acting

non sedating Brand name: ALNIX anti-histamine that selectively inhibits peripheral H1 receptors.

Hypersensitivity , cardiac fatigue, disease, drowsiness, headache, gastrointestinal discomfort, vomiting, diarrhea.