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Precipitating

Predisposing -Male -Age -Family History -Being tall for a specific age -Previous cancer/ radiation therapy -Presence of benign (noncancerous) bone disease

High grade mesenchymal tumor

Distal Femur, Proximal Tibia, Proximal Humerus

Formation of osteoid

Bulky tumor that destroys trabeculae of diseased area

Metastasize through blood streams

Lungs, Bones, Visceral, Organs

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