BOOK BASED

Risk Factor
tall for age
Repeated trauma
Hereditary
Exposure to radiation
 Causes:
DNA Mutation
Injury
Infection
Metabolic or hormonal disturbance

osteoblast
High grade mecenchymal tumor
Malignant osteoblast
Distal femur
Proximal tibia
Proliferation of abnormal osteoblast
Proximal humerus

Formation of osteoid or immature bone

Pain, swelling, tenderness Bulky tumor that destroys tuberculae of disease

Metastasize through blood stream

Lungs, bones, visceral organs