1.

Bone Tumor

Anak-Anak Dewasa
Jinak Osteochondroma Giant Cell Tumor
Osteosarcoma Plasma cell myeloma
Ganas
Ewing sarcoma Metastatic tumor

2. Tumor Jinak

Asal Lokasi Ciri-ciri Epidemiology

Metaphyse
Macroscopic
Distal femur
sessile/ pedunculated 4-10 Paling
prox tibia
cm sering
prox
Microscopic Usia <20
humerus
Osteochondroma Chondrogenic 4 layer: fibrous, kartilago, tahun
prox fibula
tulang, sum tulang Ada yang
Flat bone
Hiperselular solitary dan
ilium
Condrocyt atypia multiple
scapula.

Epiphyse- Macroscopic 20-45 tahun

Giant Cell Tumor unknown metaphyse soft and reddish brown Jarang <10
distal femur Microscopic tahun
 prox tibia Round/polygonal/elongated
prox mononuclear mixed with
humerus osteoclast-like Giant Cell
distal radius Radiology
Pelvis lytic lesion
sacrum eccentric
vertebral soap bubble
bodies

3. Tumor Ganas

Asal Lokasi Ciri-ciri Epidemiology

Microscopic
Metaphyse Tumor ganas membentuk
Sekitar lutut( matrix osteoid <25 tahun
proximal (60%)
Osteosarcoma Osteogenic
femur/ distal Radiology >40 tahun
tibia) Codman triangle (13-30%)
Sunray app

Sum tulang-sel Diafisis

Ewing sarcoma <20 tahun
neural Femur
 Tibia Microscopic
humerus rossete
onion skin

Microscopic
cartwheel app
round oval eccentric nuclei
atypical plasma cell
Vertebra
bence jones
Ribs
Radiology
Skull
Plasma Cell lytic punched out lesion
Plasma cell Pelvis > 40 tahun
Myeloma Sign and symptom
Prox femur
Clavicle pain
scapula anemia
Bone Marrow
Plasmacytosis
Monoclonal gammopathy

Microscopic
Vertebra
binucleated chondroid
prox femur
Matrix
ribs
Primer tumor( Radiology
sternum
Metastatic Ca paru, payudara, lytic/ blastic > 40 tahun
pelvis
tyroid, prostat)
skull
Sign and symptom
shoulder
pain
girdle
swelling
 fracture

4. Soft Tissue

Asal Lokasi Ciri-ciri Epidemiology

Macroscopic
Back Well circumscribed
Paling
Neck homogenous yellow cut.
sering
Lipoma Sel adiposa Abdomen Microscopic
40-60
prox extremity Mature adipocytes
tahun
gluteus small eccentric nuclei

Macroscopic
Well circumscribed
Limb Large mass
Thigh Lobulated >40 tahun
Liposarcoma Sel adiposa Retroperitoneum yellow to white Banyak di
para testicular Microscopic 60 thn
mediastinum variation in cell size
nuclear atypia
malignant lipoblast
 SF(superficial) Benign fibroblasti
Fibromatosis Palmar myofibroblastic spindle <40 tahun
Plantar cells
AF(aggresive) poorly circumscribed
Shoulder
chest wall back
abdomen
Proliferation of Anaplastic
Extremities
Fibroblastic spindle cells
Trunk
fibrosarcoma herring bone growth <25 thn
head
pattern
neck

Large deep seated

Fleshy
Necrosis
Hemorrhage >40 tahun
Lower limb
UHGPS/MFH Pseudoencapsulated Paling
trunk
Cytological pleomorphic sering
bizarre giant cell
storiform growth pattern

Embryonal
( child)
Rhabdomyosarcoma
Alveolar
(adult)
5. Perbandingan(umur)

<25 tahun 25-40 tahun >40 tahun

Osteochondroma Giant Cell Tumor Osteosarcoma

Osteosarcoma Fibromatosis Plasma Cell Myeloma

Ewing sarcoma Rhabdomyosacroma Metastatic Ca

fibrosarcoma Lipoma

Fibromatosis Liposarcoma

Rhabdomyosarcoma UHGPS/MFH
6. Perbandingan (letak)

Tulang pendek,
Epifisis-metafisis Metafisis Diafisis Soft Tissue
pipih dan vertebra
Plasma Cell Osteochondroma
Giant Cell Tumor Ewing sarcoma Lipoma
Myeloma
Metastatic Ca Osteosarcoma Liposarcoma

Fibromatosis
fibrosarcoma
UHGPS/MFH
Rhabdomyosarcoma