Previous DBT-BET-JRF Questions (Set-1)

1. Deoxy position of deoxyribose in DNA is a (A) 1st Carbon (B) 3rd Carbon (C) 2nd Carbon (D) 5th Carbon Ans: 2nd position More about, log on to:DNA 2.Which of the following transgenic crops occupies the largest area in the world? (A) Herbicide tolerant soybean (B) Herbicide tolerant maize (C) Insect resistant cotton (D) Insect resistant potato Ans: Herbicide tolerant soybean 3. The gene responsible for dwarfing character in rice is (A) Tift 23A (B) Norin 10 (C) Dee-geo-woo-gen (D) Opaque 2 Ans: Dee-geo-woo-gen Read more about: Green Revolution Genes: Dwarfing Genes of Wheat & Rice 4. Aroma in rice is due to (A) Acetyl choline (B) 4-benzyl pyrroline (C) 2-ethyl pyrroline (D) 2-acetyl-1-pyrroline Ans:2-acetyl-1-pyrroline Read more about: Aroma in Rice 5. Rifampicin is a specific inhibitor of (A) Bacterial RNA polymerase (B) RNA polymerase II (C) RNA polymerase I (D) RNA polymerase III Ans: Bacterial RNA polymerase

More about, log on to: Mode of action of inhibitors 6. The Philadelphia chromosome is (A) an example of gene amplification (B) a product of a reciprocal translocation (C) a characteristic of Burkitt's lymphoma (D) an example of duplication Ans: a product of a reciprocal translocation

Deletion of one arm of chromosome 21. Clinical symptoms: Chronic granulocytic leukemia

7. Independently folded functional unit of a protein is called a (A) motif (B) fold (C) domain (D) module Ans:domain 8. Most predominant antibody in serum is (A) IgG (B) IgD (C) IgE (D) IgA Ans: IgG

Rifampin specifically inhibits bacterial RNA polymerase, the enzyme responsible for DNA transcription

IgG: Most abundant immunoglobulin, produce in the late primary response after IgM production, predominant in secondary immune response, the one and only Ig that cross placenta. IgA: Secretory antibody, Heaviest antibody and second most abundant IgM: Macroimmunoglobulin, pentamer, does not cross placenta, also known as natural antibody, first produced antibody upon infection. IgD: Present on surface of B-cells and in serum. IgE: which is responsible for allergic reactions, mediate hyper sensitivity. These are concentrated in mucous membrane, skin and lungs.

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9. Scrapie is caused by (A) Fungal protein (B) Bacterial protein (C) Plant lipoprotein (D) Prion Ans:Prion

Prion : infectious proteinaceous particles Creutzfeld-Jacob Disease: The prion protein (PrP) is an infectious protein that converts non infectious (PrP) into infectious form, which precipitates. PrP is implicated as the causative agent of the transmissible spongioform encephalopathies, including Creutzfeld-Jacob Disease.

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Protein folding Diseases associated with Protein folding

10. Which one of the following organisms is used in Ames test? (A) E. coli (B) Streptococcus aureus (C) Pseudomonas aerogenosa (D) Salmonella typhimurium Ans: Salmonella typhimurium The Ames test

A simple and effective way to test whether a chemical is mutagenic or not. This test uses a strain of Salmonella bacteria that has a defective histidine synthesizing gene. The mutagenicity of the carcinogen can be quantified by counting the number of bacterial colonies that grow on a medium lacking histidine.

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