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1885 first cloned animals.Hans Dreisch seperated cells from two-celled sea urchin blastomers mechanically.

Each cell grew independently and formed a separate, whole sea urchin clone. 1902 Hans Speman (1935 Nobel Prize in medicine) conducted the first nuclear transfer experiment by splitting a two-celled salamander embryo into seperate cells. Each cell developed into a salamander. 1903 Herbert Webber (US Dept. Agriculture) coined the word "clon". 1928 Hans Spemann performed the first nuclear transfer experiment using salamander embryos. 1952 Robert Briggs and Thomas King used nuclear transfer technology to clone frogs from adult donor cells. 1963 J.B.S. Haldane is credited to have coined the term "clone". Tong Dizhou created the first cloned fish (asian carp) 1973 by inserting Asian carp DNA into a European crucian carp, Tong Dizhou created the first interspecies clone 1984 Steen Willadsen (British Agricultural Research Council) cloned a sheep via nuclear transfer technology. 1995 Megan & Morag: July 1995 Scottish scientists clone the sheeps Megan and Morag from differentiated embryo cells. 1996 The first mammal was cloned from a cell of an adult animal. Ian Wilmut (Roslin Institute) created the sheep Dolly. 1997 Neti and Ditto: two Rhesus monkeys were cloned by nuclear transfer at Oregon Regional Primate Research Center. Neti stands for "nuclear embryo transfer infant". Polly: the first genetically engineered cloned sheep. Gene: the first cloned cow from a fetal cell (Infigen, Inc.) Cumulina: the first mouse cloned from adult cells (University of Hawaii Medical School) ABS Global, Inc. cloned the first calf (Holstein) 1998 Noto & Kaga: first cloned cows from adult cells ((Ishikawa Prefectural Livestock Research Center) Mira: first cloned goat from embryonc cells (Tufts University, Genzyme Transgenics Corporation) 1999 A Chinese scientist claimed to have cloned a human embryo to the stage where stem cells could be harvested and then cultured. 2000 Alexis, Carrel, Christa, Dotcom & Millie: the first pigs cloned from adult cells (PPL Therapeutics). Yanyuan: the first goat cloned from adult cells (Northwest University of Agriculture, Forestry Science and technology, China) Tetra: the first Rhesus monkey 'cloned' by embryo splitting technique. Xena: Japanese research group cloned a pig (black Chinese Meishan) from fetal skin cells. The first mouflon was cloned from adult cells (University of Teramo, Italy) 2001 Noah: the first species of an endagered species (gaur) was cloned (Advanced Cell Technologies)The first rabbits were cloned from adult cells (National Institute of Agricultural Research, France)CopyCat (or Carbon Copy): the first cloned domestic animal 2003 The first banteng (bos javanicus) was cloned from adult cells (Advanced Cell Technologies, Trans Ova Genetics)Idaho Gem: the first mule was cloned from a mule fetus (University of Idaho)Prometea: first horse cloned from adult cells (Consortium for Zootechnical Improvement, Italy)Ditteaux: the first African wildcat (Felis silvestris) was cloned from adult cells (Audubon Center for Research of Endagered Species)Dewey: first deer cloned from adult cells (Texas A&M University, ViaGen, Inc.) 2004 Tabouli & Baba Ganoush: the first cat cloned by chromatin transfer technology (Genetic Savings & Clone)South Korean scientists cloned 30 human embryos and developed them over several days to the blastocyst stage. 2005 Snuppy (Seoul National University puppy): the first cloned dog 2006 Iranian doctors said they have cloned a sheep. The lamb died minutes after birth. It was the first animal cloning in Iran.First cloned ferrets (Libby and Lilly) by somatic cell nuclear transfer 2007 South Korean Scientists have cloned two females of an endangered species of wolf named Snuwolf and Snuwolffy 2008 Snuppy has become a father after the world's first sucessful breeding involving only cloned canines (Seoul National University). 2009 the first cloned camel (Injaz) was born at Dubai's Camel Reproduction Center. the first buffalo calf was born at NDRI, Karmal (India)Iran's first cloned goat was born in Isfahan 2011 A South Korean team claimed to have cloned coyotes for the first time 1. Cloning for medical purposes: Cloning animal models of disease, Cloning stem cells for research , "Pharming" for drug production.

2. Reviving Endangered or Extinct Species 3. Reproducing a Deceased Pet 4. people:To help infertile couples have children, To replace a deceased child There are two different methods or ways to clone. One way is known as embryo cloning, which is also known as 'artificial twinning' because it resembles the process in which twins develop. "Human embryo cloning starts with a standard in vitro fertilization procedure. Sperm and an egg cell are mixed together on a glass dish. After conception, the zygote (fertilized egg) is allowed to develop into a blastula (a hollow mass of cells). The zygote divides first into two cells, then four, then eight... A chemical is added to the dish to remove the "zona pellucida" covering. This material provides nutrients to the cells to promote cell division. With the covering removed, the blastula is divided into individual cells which are deposited on individual dishes. They are then coated with an artificial zona pellucida and allowed to divide and develop. The experiment by Sillman et al. showed that the best results could be obtained by interrupting the zygote at the two cell stage. Many of these pairs of zygotes were able to develop to the 32 cell stage, but no further. They might well have had the potential to develop further and even mature into a viable fetus, except that the original ovum was defective and would have died anyway."

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