Professional Documents
Culture Documents
Ethical Considerations
Documentation – ensure accurate documentation; what is
not on the chart is good as not done
Informed Consent - ensure that the client understands all
the undertakings with their consent as is signed by the
client or a responsible part if he client is a minor.
1. Conception
2. Pregnancy Termination/ Abortion
3. Stem cell research
4. Invasive procedure on children
*May include religious and moral affiliations
MALE REPRODUCTIVE SYSTEM semen travels through to exit the penis
5) Corpus cavernosa – outer erectile tissue
6) Corpus spongiosum – inner erectile tissue
7) Root – accumulation/ bundle of the nerves and blood
vessels
External
1) Glans – foreskin
2) Prepuce – excised during circumcision
3) External Urethral Meatus – opening from the urethra
4) Urethra – innermost of the body or shaft, urine and
1. Mons Pubis – pubic hair initially appears here
Internal 2. Labia Majora – on the sides
1. Scrotum – houses the testis 3. Labia Minora – going inside
2. Testis – housed by the scrotum; production of 4. Clitoris – where the labia minora meet
testosterone and sperm; primary male sex hormones superiorly
3. Epididymis – matures sperm 5. Urethral orifice – opening from the urethra; landmark for
4. Vas deferens – transports sperm from the epididymis catheterization; urine comes out
5. Seminal Vesicle (65% of semen) – produces sugar-rich 6. Vaginal orifice - head of the baby comes out first and the
fluid with fructose for sperm motility and energy opening from the vaginal canal
6. Ejaculatory duct – where the fluids combine 7. Perineal Body
7. Prostate gland 8. Anus
8. Cowper’s gland/ bulbourethral gland – reduces the
acidity of the urethra Perineum
Knowing the parts of the perineum will help you get
Physiology acquainted of the parts affecting labor and delivery
Spermatogenesis – production of sperm in the testes It plays an important role in functions such as defecation,
Sperm travels from the testis to the epididymis sexual intercourse and child birth.
from 12-20 days; matures 65-75 days; 20million
per mL/ ejaculation PHYSIOLOGY:
Endocrine Gland – hormonal influence
Pubertal development:
Increase in height and weight
Enlargement of testes and scrotum
Appearance of body hair
Penile growth and enlargement
Nocturnal emissions (sign of
spermatogenesis)
The Ejaculate of the Semen - 2.5-5ml (sticky)
- Testicle (10%)
- Seminal vesicle (65%)
- Prostate Gland (25%)
- Bulbourethral glands (minimal)
FLOW:
External
OVARIAN CYCLE
Physiology:
- Frequent urination and constipation because
the growing fetus compresses the bladder and
compresses the rectum backward.
- Ensure strong pelvic muscles to avoid
BLOOD SUPPLY OF THE UTERUS pulling down of the muscle.
Cystocele – protrusion of the bladder out of the vagina
Rectocele – protrusion of the rectum out of the vagina
Oogenesis
– the formation of female gametes
Endocrine Glands - GnRH from the Hypothalamus
signals the anterior pituitary gland to produce LH an FHS
during oogenesis. LH encourages the production of
progesterone; FSH encourages the production of Estrogen:
Hormonal Control
Estrogen – reproductive hormone in F that assist in
endometrial growth, ovulation, and calcium absorption, and
the development of secondary sexual characteristics
PUBERTAL DEVELOPMENT:
Growth spurt
Breast budding
Increase in size of pelvis
Appearance of body hair
Menstruation then ovulation
MENSTRUATION:
TERMS:
1. Dysmenorrhea – painful menstruation
Primary dysmenorrhea
absence of anatomic abnormality, high
prostaglandin levels produced by
endometrium, psychological factors
Nursing responsibilities: rest, heat, analgesics;
Secondary dysmenorrhea – underlying anatomical
abnormality/pelvic inflammatory diseases/uterus
2. Amenorrhea – absence of menstruation
Primary amenorrhea – menarche has never
occured, hormonal alteration
Secondary amenorrhea - cessation of menstrual
cycle for more than 3 months after regular
cycles have been established, may be caused by
pregnancy/other medical conditions
3. Oligomenorrhea – infrequent menstruation
4. Polymenorrhagia – frequent menstruation
5. Hypomenorrhea – abnormally short menstrual cycle
(less than 28 days)
6. Hypermenorrhea – abnormally long menstrual cycle
(more than 28 days/ more than 31 days)
7. Metrorrahgia – the abnormal bleeding between
menstrual cycles or the inter-cyclic bleeding related to
cancers and other gynecologic problems.
8. Meorrhagia – excessive/perfuse menstrual flow
caused by infections/uterine tumors/hormonal
imbalance
9. Menopause – end of a woman’s reproductive abilities
NURSING RESPONSIBILITIES
Exercise (yoga/aerobics prior to menses)
Diet (restrict sugar, salt, or stimulants; encourage
complex cars and protein)
Activities of Daily living (rest and
verbalization of any concerns)
Nutrition
Pain Relief
Rest & Psychological Support
FETAL FORMATION
FERTILIZATION
Occurs once a mature egg cell unites with a sperm cell at
the ampulla.
Can also be called conception, fecundation, or
impregnation.
Each sperm reaches the site of fertilization at the ampulla
of the fallopian tube shortly after ejaculation often only
within five minutes but an average of 46 hours seems When fertilization occurs, the male pro nucleus unites with
more reasonable. the female pro nucleus. Thus, the chromosome, diploid 46
Sperm must be in the genital tract 4- 6 hours before they is restored, on a new cell. The zygote is created with new
are able to fertilize an egg. It is at this time when the combination of genetic material which creates a unique
enzyme needed to dissolve the semen substance individual from the parents and anyone else.
hyaluronic acid that holds together the cells covering the
ovum is activated. SEX IDENTIFICATION: CHROMOSOME PAIRS
Hyaluronidase - enzyme that dissolves hyaluronic acid The ovum releases 23 chromosomes while the sperm
covering the ovum. releases 23 chromosomes as well. It then unites forming 23
Factors affecting fertilization: pairs of chromosomes, total 46.
1. Equal maturation of sperm and ovum. Autosomes - 22 pairs
Both the sperm and the ova should be Sex chromosome - last pair of chromosome
mature. Determines the sex/gender of the fetus.
2. These cells should undergo 2 processes: If the female gives off an X and the male gives of an
a) Sperm Capacitation - ability or capacity X, the fetus is a female (XX).
of sperm to reach the ovum. If the female(ovum) gives off an X and male(sperm)
Process by which the sperm becomes gives off a Y chromosome, the fetus will be male
hypermobile, breaking down the plasma (XY).
membrane exposing the acrosomal
membrane or covering of the sperm head, EMBRYO DEVELOPMENT: EMBRYOGENESIS
allowing the sperm to bind with the zona Process that follows fertilization.
pellucida of the ovum. The fertilized egg, travelling in the fallopian tube, will
b) Acrosomal Reaction - ability of the divide into 2, 4, 8 , 16 cells, etc.
sperm to penetrate the zona pellucida and This will result in a ball-like structure
cell membrane. Contains many cells inside it
Follows capacitation Morula - ball structure with 16 cells
The acrosomal covering of the head of the Blastula
sperm contains hyaluronidase. Morula further divides to form this
As millions of sperm surround the ovum, Stage wherein the cells arrange themselves into a
they deposit minute amounts of hollow mass structure.
hyaluronidase in the corona radiata, the They align on the edges leaving a cavity that will soon
outer layer of the ovum. be filled with fluid.
This allows the sperm head to penetrate Blastocyst - the stage where the embryo will have cells that
the ovum. have got differentiated and will differentiate further.
Differentiation - one cell gets differentiated from the other
cells in its vicinity.
The blastocyst is now a mass containing differentiated
cells.
As it grows further, the body of the embryo begins to
develop. For its proper growth and development, embryo
needs nutrition.
As soon as the sperm penetrates the zona pellucida, it Implantation- blastocyst will have to attach or implant itself
makes contact with the vitelline membrane of ovum. on the mother’s body at one fixed position ---uterus
A cellular change then occurs in the ovum that inhibits Reasons for implantation:
other sperms to penetrate. The cellular change is mediated 1. Deriving nutrition
by the release of material from the cortical granules, 2. Give away wastes
organelles found just below the egg surface. 3. Exchange gases
All these are served through the barrier, an organ, called the
placenta.
The placenta connects baby to the mother.
Fetal stage - stage where the organs of the baby start to
develop such that they can be identified
The embryo can now be called a fetus.
Fetus grows in the uterus after taking the required Implantation/Nidation - happens in the fundal portion or
amount of time and when the growth is completed, the upper one third of the uterus; can be anterior (to the
the child can now enter the world mother’s front) or posterior (to the mother’s back).
Abnormal implantation sites are fallopian tubes leading to
TYPES OF EMBRYOGENESIS BASED ON LOCATION: ectopic pregnancies or the lower uterine segment which
1. Viviparity - the fetus grows inside the mother’s body. causes placenta previa.
a) Viviparous organisms (humans) During implantation, the blastocyst completely buries itself
2. Oviparity - the fetus grows outside of the mother’s body. in the endometrium.
a) Oviparous organisms (ex. Hens) Trophoblast- responsible for attaching itself to
maternal side
External Fertilization- fertilization process that occurs After this, the embryo encloses itself in an amniotic sac
outside the female body. filled with amniotic fluid.
Ex. Fertilization in frogs Amniotic Sac- thin but tough transparent pair of membranes
that hold a developing embryo
FETAL FORMATION Amnion- inner portion of these fetal membranes
Encloses the amniotic cavity, amniotic fluid, and the
fetus.
Chorion- outer membrane
Contains the amnion and is part of the placenta.
The Langerhans layer- part of the placenta, prevents
penetration of viruses in the early stage of pregnancy.
ABNORMAL IMPLANTATIONS
Ectopic Pregnancy
Implantation of the embryo, other than the uterus.
It can be fatal if detected late because the fallopian
tube may burst due to the growing embryo.
Blastocyst- fluid filled cavity that reaches the uterine
cavity
Important part of embryonic development
Over the next three to four days of development, a
differentiation of cells as to their specific potencies occurs.
The reorganization of the morula follows forming a Low Implantation /Placenta Previa
blastocyst. Possible cervix obstruction or the passageway for fetal
Morula- jam-packed cell of divided differentiated cells. delivery.
Once the cells accumulate in one area forming a Ideal delivery: head first → fetus → placenta follows
cavity, it becomes a blastocyst. Usually complications occur late in the pregnancy or
This is the stage when there is a cavity in the morula once mother goes into labor
called the blastocele Usually detected late
When it enters the uterine cavity, the cavity enlarges and
pushes the morula cells into an outer layer of cells called
the trophoblast.
Trophoblast- portion that attaches itself to the
endometrium of the uterus.
Along with this is an inner cell mass attached to one
side of the blastocyst. The division and
reorganization has consumed all the energy of the
zygote that it becomes necessary for the blastocyst to
embed or implant itself in the uterine wall for
nourishment, for its further development
PLACENTA
IMPLANTATION
Duncan- maternal side
Dirtier side due to the rugated part, a beefy-like
structure of the placenta called the cotyledons.
Schultz- fetal side
Portion where the fetus lies.
Decidua- as the embryo implants itself in the endometrium Shiny and clean
of the uterus, the endometrial lining thickens Upon placental delivery, it is the nurse’s responsibility to
The decidua is supported by HCG or the Human take note of the cotyledons. If there are missing cotyledons,
Chorionic Gonadotropin Hormone, an essential inform the doctor immediately. This implies retained
hormone that helps maintain pregnancy. placental fragments which can cause bleeding to the mother
Approximately 5- 10mm thick. postpartum.
Decidua basalis- portion beneath the site of the If it’s D for dirty, it is the Duncan. If it’s S for shiny, it’s
implantation. the Schultz.
Decidua capsularis- portion overlying the developing
fetus. PLACENTAL HORMONES
Decidua parietalis or decidua vera- lines the remainder of 1. Human Chorionic Gonadotropin Hormone (HCG)
the uterus Secreted as early as 8-10 days after fertilization.
Trophoblast- forms a hair-like structure called the Detected in the serum as early as the time of implantation
chorionic villi. by the most sensitive pregnancy tests
Chorionic villi and the decidua basalis forms the placenta Present in urine and blood until 1-2 weeks postpartum.
Placenta- organ that develops in the uterus during When women miss their menstruation, they immediately
pregnancy buy test kits which detect the presence of HCG.
Provides oxygen and nutrients for the growing baby HCG suppresses the rejection of placenta
Removes waste products from the baby’s blood. Prolongs the life of the corpus luteum which produces
The placenta attaches to the wall of the uterus and the fetal progesterone in the first few weeks
umbilical cord arises from it and has a discoid shape. Responsible for the nausea and vomiting experienced by
The placenta matures when it reaches 12 weeks and it is in pregnant women.
its utmost effectiveness when it reaches 40-42 weeks age Not all women that have high HCG are pregnant.
of gestation. HCG is also produced in other conditions such as H Mole
AOG or age of gestation - refers to the age of pregnancy. or Hydatidiform Mole which follows the symptoms of
Beyond 42 weeks of pregnancy, the placenta will lose its pregnancy.
function. Hydatidiform Mole- rare complication of pregnancy
characterized by the abnormal growth of trophoblasts.
FUNCTIONS OF THE PLACENTA Make women think they are pregnant because the
1. Transport of nutrients and fluid. womb will grow large
a) Alpha-fetoprotein (AFP)- synthesized by fetus; fetus Treated similarly to cancer
brings back to the mother N= 400,000 IU/24 hours.
2. Excretion of amniotic fluid.
Clear straw fluid produced by the fetus and mother which
helps nourish the fetus
3. Respiratory organ of the fetus.
Size of placenta affects amount of blood exchanged
4. Protective Barrier
Placental barrier to some substances and organisms like
heparin, bacteria
Ineffective for virus, alcohol, nicotine, antibiotics,
depressants stimulants
5. Secretes Hormones. After the first 2mos of gestation, estrogen and progesterone is
Estrogen, progesterone, HCG, HPL/HCS produced by the placenta
1. Progesterone- maintain pregnancy and prevent uterine
contraction
2. Estrogen- mammary gland and uterine development.
3. Human Chorionic Somatomamotropin or Human Placenta
Lactogen
Secreted by the third week after ovulation
It influences somatic cellular growth of the fetus.
Also resembles the growth hormone.
Principal diabetic or diabetogenic factor as it is a
major insulin antagonist or glucose staring hormone.
Prepares the breast of the mother for lactation.
AMNIOTIC FLUID A bundle of one umbilical vein that carries oxygenated
Clear, straw-colored fluid in which the fetus floats blood to the fetus and two umbilical arteries that carry
Slightly alkaline at pH 7.2 deoxygenated blood from the fetus to the placenta.
Originates from both the fetus and mother AVA ( artery vein artery) - two arteries & one vein
Produced by: Determinant for heart and kidney diseases
Amniotic membrane Covered by Wharton’s Jelly - gelatinous
Fetal urine contributes to the fluid by the 10th week mucopolysaccharide, which prevents the cord from
of fetal life compression.
800 - 1,200 mL Blood volume in the cord prevents cord compression.
Oligohydramnios- if the amniotic fluid index drops below Cord extends from the fetal surface of the placenta to the
500 mL umbilicus of the fetus.
May imply a kidney problem of the fetus Umbilical cord transports oxygen and nutrients to the fetus
Polyhydramnios- excessively large amount of amniotic and returns metabolic wastes, including carbon dioxide,
fluid from the fetus to the placenta
May imply esophageal atresia. Nuchal Cord - cases wherein the umbilical cord wraps
Atresia- blocked esophagus around neck of the fetus; it is very common and may occur
In this case the fetus is unable to ingest during pregnancy, labor, and delivery.
amniotic fluid causing excessively high
amounts STAGES OF INTRAUTERINE DEVELOPMENT
Meconium-stained- amniotic fluid is green in color 1. Pre-embryonic stage
Meconium is fetal stool expelled intra-uteri 1 st 2 weeks after fertilization wherein the fertilized ovum
especially if the gestational age goes beyond the implants itself on the uterus and becomes a zygote.
normal span. Predifferentiation of organs occur.
Gold colored amniotic fluid- may signify a hemolytic All or none law- when the ovum is exposed to a teratogen
disease or the breakdown of red blood cells at a faster rate. or any harmful substance to the fetus. This implies the
It causes the release of high bilirubin causing yellow ovum is damaged and is out in spontaneous abortion or it is
discoloration. not affected at all and may continue to grow normally.
Nurses should take note of the color and report it to the 2. Embryonic Stage
doctor immediately 3-8 weeks of gestation/ after fertilization
Period of organ differentiation or organogenesis.
Most dangerous period of the development--a teratogen or
any harmful agent that is introduced in this stage may result
in severe organ malformation and dysfunction resulting to
Purposes: congenital defects of the newborn.
1. Protective cushion or shock absorber- it separates the fetus 3. Fetal Stage
from the membrane allowing symmetrical growth and free 8 weeks up to birth
movement of the fetus. Period of post-differentiation
2. Medium of excretion. If the fetus is exposed to a teratogen at this time,
3. Specimen- it serves as a fetal drink and a specimen for malformation is least likely to occur.
diagnostic exams to determine fetal well-being or its absence If ever the fetus is affected, the effects will most likely be
4. Fetal temperature- maintenance of fetal temperature and an alteration in size or function.
equalizes uterine pressure and prevents marked interference
with placental circulation during labor. We can see a fetus being viable or being able to survive
outside of the uterus after birth, natural or induced when
UMBILICAL CORD supported by up to date medicine
Age of Viability- at least 20-24 weeks age of gestation and
should be greater than 500 grams.
Abortus/ product of abortion- any fetus born less than
these values are
CARDIOVASCULAR SYSTEM
Develops from the mesoderm
Starts at the 16th day of life
Fetal Heart Tone / FHT- is audible through the fetal
doppler at 10-12 weeks AOG
via Fetoscope at 16 weeks AOG
via Stethoscope at 20 weeks AOG
Fetal Heart Rate or FHR is irregular in the first few weeks
FLOW:
but regulates into 110-160bpm starting 28 weeks.
Structures involved in fetal circulation: placenta, umbilical
Fetal blood is hemoconcentrated--they normally have high
vein, ductus venosus, ductus arteriosus, foramen ovale,
concentration of red blood cells compared to adults
umbilical arteries
Blood rich in nutrients and oxygen supplied via the placenta
FETAL CIRCULATION
flows to the umbilical vein to the ductus venosus.
From here, blood flows from ductus venosus to the inferior
vena cava up to the right atrium. This blood mixes with
blood returning to the heart from the upper body via the
superior vena cava, from the lower body via inferior vena
cava
In the right atrium, some of the blood flows to the right
ventricle and some flows to the foramen ovale to the left
atrium and into the left ventricle where it is pumped to the
aorta to the body
Blood that flows into the right ventricle is then pumped into
the pulmonary artery
The lungs have tighter/narrow vessels because it is fluid-
filled rather than air-filled. The vessels in the lungs are
narrow creating higher resistance to blood flow into the
Three shunts- these are small passages that direct blood
lungs. Due to the high resistance to blood flow in the
that need to be oxygenated
pulmonary circulation and the low resistance to blood flow
Purpose of these shunts is to bypass the lungs and the
in the systemic circulation, blood pumped into the
liver. These organs will not work fully until after
pulmonary artery by the right ventricle is more likely to
birth.
flow into the ductus arteriosus and into the aorta
Foramen Ovale- shunt that bypasses the lungs
Due to the high blood flow from the superior and inferior
moves blood from the right atrium of the heart to the
vena cava up to the right atrium, pressure in the right atrium
left atrium which abnormally happens in adults.
are higher. This promotes blood flow through the foramen
Ductus Arteriosus- moves blood from the pulmonary
ovale at the atrial level
artery to the aorta.
Only 8% of right ventricular output flows into the lungs
Oxygen and nutrients from the mother’s blood are sent
providing nutrients for the developing lung tissue.
across the placenta to the fetus. The enriched blood flows
Most of the blood passes through the ductus arteriosus into
through the umbilical cord to the liver and splits into three
the aorta and out to the rest of the body. The umbilical
branches; the blood that reaches the inferior vena cava.
arteries allows blood to flow from the body back to the
This is a major vein connected to the heart.
placenta to be enriched with oxygen and nutrients.
collapse and improving infant’s ability to maintain
AFTER BIRTH respirations in the outside environment. This is one basis of
When born and the baby takes the first breath, the the determining viability of the fetus. Without the
umbilical cord is clamped and the placenta is removed surfactant, the newborn is not able to breathe on its own in
from the systemic circulation the extrauterine life having no placenta for gas exchange.
Immediately, there is a transition from fetal to post-natal In cases wherein the mother goes into labor or is about to
circulation begins deliver the fetus, they are given intramuscular doses of
With the elimination of the placenta from the circulation, steroid or betamethasone. Some doctors would prescribe
systemic vascular resistance now rises. With each breath, dexamethasone. This steroid is believed to stimulate the
more alveoli in the lungs expand and the surrounding synthesis and release of the surfactant.
vessels dilate in response to the presence of oxygen In cases wherein the newborn is still pre-term they are given
Pulmonary pressure will start to decrease, although through endotracheal tube or a tube is inserted into the
pulmonary pressures are lower than systemic pressures lungs, giving the baby artificial surfactant (betamethasone).
within minutes after breath , but it is not until the 6th to Common brand is Survanta.
8th week that pulmonary vascular resistance decreases to
normal NERVOUS SYSTEM
In the postnatal circulation, blood will no longer flow Develops from intrauterine from ectoderm
through the foramen ovale or the ductus arteriosus Neural plate- a thickened portion of the ectoderm, is
The increase in left atrial pressure after birth forces the apparent by 3rd week AOG
septum primum against the septum secundum, Top portion- differentiates into the neural tube which
functionally closing the foramen ovale. Within three will form the CNS, brain, and the spinal cord.
months, the foramen ovale permanently closes as fibrin Neural crest- will develop the PNS.
deposits fuse the layers of septal wall together. All parts of the brain (cerebrum, cerebellum, pons, medulla
While PFO (propatent foramen ovale) may close by oblongata) form in the uterus, although none are completely
this time, it also may not close in some adults, the mature at birth.
shunt via PFO via birth is usually small Growth proceeds rapidly during the first year and continues
The ductus arteriosus closes soon after birth as the infant at high level until 5 or 6 years of age.
begins to breathe. Normally, the ductus closes completely Spinal cord disorder such as meningocele or herniation of
in 4-10 days. meninges may occur because of lack of folic acid which is
The ductus venosus is open at the time of birth, making present in green leafy vegetable and pregnancy vitamins.
central venous access possible through the umbilical vein. That is why pregnant women may be taking folic acid as
As fibrin infiltrates the ductus venosus, it usually closes prenatal vitamins.
within three to seven days. After it closes, the remnant is
called ligamentum venosum. DIGESTIVE SYSTEM
Within a week after birth the umbilical vein and the
umbilical arteries are infiltrated with fibrin
RESPIRATORY SYSTEM
Develops from the endoderm
The GI tract of the fetus is sterile, meaning there is no
bacteria or normal flora present in the system
Because vitamin K is synthesized by the action of bacteria
in the intestine, vitamin K level are low in a newborn
Common congenital defects in the GI system of the fetus is
atresia and stenosis
Atresia is a condition wherein an orifice or passage in the
Emerges from the endoderm body is abnormally closed or absent
Not functional as a whole, until after birth of the newborn. Stenosis is the narrowing of the GI tract
It develops from a hollow tube of esophagus and trachea Esophagus and trachea forms one hollow tube initially,
until 4th week AOG. failure to separate or develop distinctly may result in atresia
Respiratory movement is noted at 3rd month of gestation. or stenosis which may pose problems of feeding in the
At 24 weeks AOG, the newborn starts to produce extrauterine life.
surfactant. This is a phospholipid substance that is formed In cases wherein the abdomen fails to close anteriorly, this
and excreted at 24th weeks of pregnancy. It decreases may result into omphalocele or a birth defect in which an
alveolar surface tension on expiration preventing alveolar
infant’s intestine or other abdominal organs are outside the Develops at 16 weeks AOG and diminishes at end of
body because of a hole in the naval area 36 weeks AOG
The intestines are covered only by a thin layer of tissue Vernix Caseosa- cream cheese like substance is important
and can be easily seen. for lubrication and prevention of the skin from macerating
Meconium- first stool of the fetus in utero.
Composed of materials ingested during fetal Forms by the end of 20 weeks AOG.
development, which includes intestinal epithelial
cells, lanugo, mucus, amniotic fluid, bile, and water. IMMUNE SYSTEM
Viscous and sticky like tar IgG maternal antibodies cross the placenta into the fetus as
Color is a very dark olive green early as 20 weeks AOG and certainly by the 24th week of
Almost odorless. intrauterine life to give fetus temporary passive immunity
An important neonatal nursing responsibility is recording against diseases for which the mother has antibodies.
that a newborn has passed meconium, as this rules out a The level of acquired passive IgG peaks at birth and
stricture or non-canalization of the anus. decreases over the next 8 months as infant builds up his/her
The liver is active throughout gestation. Functioning as a own stores of IgG as well as IgA and IgM
filter between the incoming blood and the fetal circulation IgA and IgM are produced after infection
and as deposit site for fetal spores such as iron and Because the passive immunity received by the newborn has
glycogen. It is still immature at birth. This can possibly already declined substantially by about 2 months, basic
lead to hypoglycemia--low glucose/sugar and immunization starts
hyperbilirubinemia---high bilirubin levels. These are A fetus is capable of active antibody production late in
problems that may arise during the first 24 hours after pregnancy because IgA and IgM antibodies cannot cross the
birth. placenta, their presence in a newborn is proof that the fetus
The liver does not prevent recreational drugs or alcohol has been exposed to a disease.
ingested by the mother from entering the fetal circulation.
ENDOCRINE SYSTEM
REPRODUCTIVE SYSTEM Function of endocrine organs begins along with the
Develops from the mesoderm. neurosystem development
A child’s sex is determined at the moment of conception Fetal pancreas produces insulin needed by the fetus
via spermatozoon carrying an x or y chromosome and can Insulin- one of the few substances that does not cross
be ascertained as early as 8 weeks of chromosomal the placenta from the mother to the fetus
analysis. Thyroid and parathyroid glands- play vital roles in fetal
At 6 weeks AOG, the gonads (ovaries or testes) form. metabolic function and calcium balance
If testes is formed, testosterone is secreted. Apparently Fetal adrenal glands supply a precursor necessary for
influencing the sexual neutral genital duct to form other estrogen synthesis by the placenta
male organs.
In the absence of testosterone secretion, female organs MUSCULOSKELETAL SYSTEM
will form. The testes first forms in the abdominal cavity During the first 2 weeks of fetal life, cartilage prototypes
and do not descend into the scrotal sac until the 34th to provide position and support to the fetus
38th week AOG. Because of this many male pre-term Ossification of this cartilage into bone begins at about the
infants are born with undescended testes. These children 12th week and continues all throughout fetal life and into
need follow-up care to be certain that their testes descend adulthood
when they reach what would have been the 34th to 38th Carpals, tarsals, and sternal bones- generally do not ossify
week AOG. Testicular descent does not occur as readily in until birth is imminent
extrauterine life as it would in utero. Fetal movement at 11th week seen via ultrasonography
Mother does not feel this movement or Quickening until 16-
URINARY SYSTEM 20weeks of gestation
The presence of kidneys does not appear to be essential Usually felt earlier in multigravida women
for life before birth
The placenta clears the fetus of waste products. Urine is FETAL MILESTONE
formed by the 12th week AOG and is excreted into the The fetus develops approx for:
amniotic fluid by the 16th week AOG 267-280 days
At term, fetal urine is excreted at a rate of 500mL/ day 9 calendar mos
Oligohydramnios- amount of amniotic fluid below normal 40 weeks
can suggest fetal kidneys are not secreting adequate 3 trimesters
urine. 10 lunar mos
INTEGUMENTARY SYSTEM
The skin of the fetus appears thin and almost translucent
until subcutaneous fat begins to be deposited at about 36
weeks AOG
Lanugo- soft downy hairs that cover the skin, that serves
as insulation to preserve warmth in utero.
MONTH 3
Baby’s arms, hands, fingers, feet and toes are fully
formed. Baby can open and close its fists and mouth.
Fingernails and toenails are beginning to develop and
FETAL DEVELOPMENT MONTH BY MONTH the external ears are formed
The beginnings of teeth are forming. Baby’s
reproductive organs also develop, but the baby’s
gender is difficult to distinguish on ultrasound
By the end of the 3rd month, baby is fully formed. All
the organs and extremities are present and will
continue to mature in order to become functional
The circulatory and urinary systems are working and
the liver produces bile. At the end of the 3 rd month,
baby is about 4 inches long and weighs about 1 ounce
MONTH 1 Since your baby’s most critical development has taken
As the fertilized egg grows, a water-tight sac form around place, your chance of miscarriage drops considerably
it, gradually filling with fluid. This is called the amniotic after 3 months
sac, and it helps cushion the growing embryo
The placenta also develops. The placena is a round, flat
organ that transfers nutrients from the mother to the baby,
and transfers wastes from the baby
A primitive face will take form with large dark circles for
eyes. The mouth, lower jaw, and throat are developing.
Blood cells are taking shape and circulation will begin
The tiny “heart” tube will beat 65x a minute by the end of
the 4th week. By the end of the first month, baby is about
1/4 inch long-- smaller than a grain of rice.
MONTH 4
Baby’s heartbeat may now be audible through an
instrument called a doppler. The fingers and toes are
well-defined. Eyelids, eyebrows, eyelashes, nails, and
hair are formed
Teeth and bones become denser. Baby can even suck
his or her thumb, yawn, stretch, and make faces.
MONTH 2 The nervous system is starting to function
Baby’s facial features continue to develop. Each ear The reproductive organs and genitalia are now fully
begins as a little fold of skin at the side of the head. developed, and your doctor can see on ultrasound if
Tiny buds that eventually grow into arms and legs you are having a boy or a girl
are forming. Fingers, toes, and eyes are also forming. By the end of the 4th month, baby is about 6 inches
The neural tube (brain, spinal cord, and other neural long and weighs about 4 ounces
tissue of the CNS) is well formed. The digestive tract
and sensory organs begin to develop. Bone starts to
replace cartilage.
The head is large in proportion to the rest of the
baby’s body. By the end of the 2 nd month, baby is
about 1inch long and weighs about 1/30 of an ounce
At about 6weeks, baby’s heart beat can usually be
detected. After the 8th week, your baby is called a
fetus instead of an embryo
MONTH 5
You may begin to feel your baby move, since he or
she is developing muscles and exercising them. The
first movement is called quickening
Hair begins to grow on baby’s head. Baby’s
shoulders, back and temples are covered by a soft MONTH 8
fine hair called lanugo. This hair protects your baby Baby will continue to mature and develop reserves of
and is usually shed at the end of the baby’s first week body fat
of life You may notice that your baby is kicking more
Baby’s skin is covered with a whitish coating called Baby’s brain is developing rapidly at this time and
vernix caseosa. This “cheesy” substance is thought your baby can see and hear
to protect baby’s skin from the long exposure to the Most internal systems are well-developed, but the
amniotic fluid. This coating is shed just before birth lungs may still be immature.
By the end of the 5th month, baby is about 10 inches Baby is about 18 inches long and weighs as much as 5
long and weighs from 1/2 to 1 pound pounds
MONTH 6
Baby’s skin is reddish in color, wrinkled and veins MONTH 9
are visible through the baby’s translucent skin Baby continues to grow and mature: the lungs are
Baby’s finger and toe prints are visible nearly fully developed
Eyelids begin to part and the eyes open Baby’s reflexes are coordinated so he or she can blink,
Baby responds to sounds by moving or increasing the close the eyes, turn the head, grasp firmly, and
pulse. respond to sounds, light, and touch
You may notice jerking motions if baby hiccups Baby is definitely ready to enter the world!
If born prematurely, baby may survive after the 23 rd You may notice that baby moves less due to tight
week with intensive care space
By the end of the 6th month, your baby is about 12 Baby’s position changes to prepare itself for labor and
inches long and weighs about 2 pounds delivery
The baby drops down in your pelvis. Usually the
baby’s head is down toward the birth canal
Baby is about 18-20 inches long and weighs about 7
pounds
Categories:
A. Absence or Non-apparent – no changes from the
baseline
B. Minimal – small fluctuations from the baseline (either
Several actions or procedures are helpful in detecting increase or decrease of heart rate)
and documenting that the fetus is not only growing C. Moderate – the amplitude range is 6-25 beats per
but apparently healthy. Most basic assessment is minute; if greater than 25, this is called marked
determining the following: variability
1. Fetal Heart Rate (110-160 bpm at 28 weeks) Example: Basic or basal fetal heart rate is 110,
Used fetal doppler, fetoscope or stethoscope having an increase of 116-120 would mean a
2. Fetal Movement “quickening” (10 kicks/hr) (2 in 10 moderate variability
minutes) D. Acceleration – increase of FHR related to the uterine
Taught on how to do this at home to give them contraction or intrauterine stress
an idea or the sense of urgency to when to see E. Deceleration – drop of FHR also caused by uterine
their doctor contraction or intrauterine stress
Quickening (movement in pregnancy when the
pregnant woman starts to feel or perceive fetal Fetal Formation:
movement in the uterus; occur at 18 to 20 weeks
and peaks at 28 to 38 weeks)
Moves at least 10 times per day
A fetus not receiving enough nutrients because
of placental insufficiency has greatly decreased
movements; asking a woman to observe and
refer the number of movements the fetus is
making offers a gross assessment of fetal well-
being
“Sadovsky Method”
ask the woman to lie in a left recumbent
position p̄ a meal and record how many
fetal movements she feels over the next When assisting pregnant client in rhythm strip testing,
hour; every after meal the fetus is active procedures, or tests, we assist them in left side lying
that is why it is the best time to check fetal position or semi-fowler (have them in semi-fowler
movement p̄ meal position before doing the left-side lying position)
10-12 kicks per hour (2 in 10 minutes); if Have this in a lounge chair, examination table or bed
less than 10 movements occur in an hour. with elevated backrest to prevent uterus from
The woman repeats the test for the next compressing the vena cava and causing supine
hour. hypotension syndrome or vena cava syndrome
Duration of test: 2 hours If you let the woman lie towards the left, this will
She should call healthcare provider if feels release the pressure occluding the inferior vena cava;
fewer than 10 movements half the normal if the mother maintains complete bed rest flat on her
number during the chosen 2 hours back, it can cause hypotension or poor circulation due
to the compression of the inferior vena cava measures the response of the fetal heart rate to
Rhythm Strip Testing: requires woman to remain in a the fetal movement
fairly fixed position for 20 minutes. As a nurse, you
should:
1. Keep her well-informed of the purpose of
the test
2. How it is interpreted
3. The meaning of the results after the test
Oxytocin Challenge Test – medication or Visually attach the mother to a CTG q4h until she
artificial hormone which induces contraction is in the labor room until she delivers the newborn
to the uterus and take it for 10 minutes at least.
Nipple Stimulation test – rolling nipple
between the fingers induces the release of 6. Vibroacoustic Stimulation – applied to mother’s
natural oxytocin which causes the uterus to abdomen. This produces a sharp sound of approximately
contract or induce stress to the fetus. 80 decibels at a frequency of 80 hertz, startling and waking
the fetus.
Monitor the relation of fetal heart rate with the
contraction of uterus. Used in conjunction with stress testing or nonstress
testing. Sound is induced to awaken the baby and
Results: monitor accurately the fetus movements.
“NEGATIVE” (normal) – shows no
deceleration on 3 contractions.
“POSITIVE” (abnormal) – on CTG with
3 contractions and with deceleration
CardioTocogram (CTG)
Used in rhythm strip testing, nonstress testing,
contraction stress testing
7. Ultrasonography (Ultrasound) – used tool in modern
obstetrics.
Purpose: effect of contraction to the fetal well-
being. Contraction will serve as the stressor Can diagnose pregnancy as early as 6 weeks
Cardio – heart gestation, confirm the presence, size, and location
Toco – contraction of placenta and amniotic fluid
Establish if fetus is growing and has no gross
anomalies such as hydrocephalus, anencephaly, or
spinal cord, heart, kidney and blood defects
Establish sex if penis is revealed, presentation and
position of fetus, predict maturity by measurement
of biparietal diameter of the head
Before ultrasound examination, make sure woman
has received a good explanation of what will
happen and reassurance that the process does not
CTG paper – shows the relation between FHR involve x-rays
(upper graph) and uterine contraction (lower It is safe for father to remain in the room for the
graph) test
Contraction – can see the intensity, how strong it For the sound waves to reflect best in the uterus to
is, how frequent, and how close is one contraction be held stable, it is helpful if the woman has a full
to the other bladder at the time of the procedure. To ensure
this, have her drink a full glass of water every 15
minutes begin 90 minutes before the procedure Placentas can be graded by ultrasound as:
and not void until after the procedure 0 – within 10 to 24 weeks
Have the woman up to the examination table and 1 – within 30 to 32 weeks
drape for modesty but with abdomen exposed. 2 – 36 weeks
To prevent supine hypotension syndrome or vena 3 – 38 weeks (fetus is mature)
cava syndrome, place towel under the right
buttock to tip her body slightly so that the uterus 11. Maternal Serum
will roll away from the vena cava
Gel is applied to her abdomen to improve the
contact of the transducer. Be certain gel is room
temperature or warmer because it can cause
uncomfortable uterine cramping
Alpha-feto protein (AFP) – if fetus has an open body
Doppler ultrasound velocimetry – uses ultrasound but defect, there will be an increase level of AFP produced
focuses on the velocity at which red blood cells in the by the fetal liver and will be present in the amniotic
uterine and fetal vessels travel. fluid because of leakage of the AFP into the fluid
which can be detected in the serum.
8. Biophysical Profile – prenatal test used to check on the
baby’s well-being than any single assessment. May be Level will be decreased in case the fetus has
done as often as daily during high-risk pregnancy. chromosomal defects such as down syndrome.
AFP
Acetylcholinesterase
Bilirubin
Genetic Analysis
Color
Score: Fibronectin
8- 10 (fetus is doing well) Inborn Errors of Metabolism
6 (suspicious) Lecithin/ Sphyngomyelin Ratio (2:1)
Less than 4 (fetus is Endo carding)
Major risks include:
9. Modified Biophysical Profile - Trauma
a. Amniotic Fluid Index (AFI) - Infection
b. Nonstress testing (NST) - Abortion
- Pre-time labor
If the MBPP shows abnormal finding, then a full
biophysical profile is done. Since this is an invasive procedure, informed consent
is a MUST. It is done starting at 18 weeks AOG up to
10. Placental grading 30ml of amniotic fluid is obtained.
Preparation: We ask the woman to void to reduce the
size of the bladder and prevent an in advert puncture.
If the bladder is full or large, the needle might hit the Infectious agents/viruses e.g. T-O-R-C-H
bladder instead of puncturing the amniotic sac. Toxoplasmosis
Position: Supine, Have the woman up to the Other diseases like syphilis
examination table and drape for modesty but with Rubella or German measle
abdomen exposed. Cytomegalovirus
To prevent supine hypotension syndrome or vena Herpes Simplex type 1 & 2)
cava syndrome, place towel under the right buttock
to tip her body slightly so that the uterus will roll People infected with these diseases should be kept
away from the vena cava away from pregnant women since they are highly
teratogenic.
13. Percutaneous Umbilical Blood Sampling – done
during the 2nd to 3rd trimester and uses ultrasound to FDA Pregnancy Categories
locate the umbilical cord. Cord blood is aspirated and
tested.
Cordocentesis
Via UTZ