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GNIPST BULLETIN 2013

1118-1177-4796-9849-7562-5062

TO GROW AS A CENTRE OF EXCELLENCE IN THE FIELD OF PHARMACEUTICAL AND BIOLOGICAL SCIENCE

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22nd November , 2013

Volume No.: 30

Issue No.: 03

Vision

Contents
• Message from GNIPST • Letter to the Editor • News Update • Health awareness • Disease Outbreak News • Forth Coming Events • Drugs Update GNIPST Photo Gallery
For your comments/contributionOR

• Campus News • Student’s Section • Editor’s Note • Archive

For Back-Issues,
mailto:gnipstbulletin@gmail.com

1 EDITOR: Soumya Bhattacharya •

GURU NANAK INSTITUTE OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY

22-11-2013

MESSAGE FROM GNIPST
GNIPST BULLETIN is the official publication of Guru Nanak Institute of Pharmaceutical Science & Technology. All the members of GNIPST are proud to publish the 30th Volume of “GNIPST BULLETIN”. Over the last two years this bulletin updating readers with different scientific, cultural or sports activities of this prestigious institute and promoting knowledge of recent development in Pharmaceutical and Biological Sciences. Student’s section is informing readers about some curious facts of drug discovery, science, sports and other relevant fields. We look forward to seeing your submission and welcome comments and ideas you may have.

LETTER TO THE EDITOR.

NEWS UPDATE

World Toilet Day, 2013(19th November, 2013)
World Toilet Day was observed on 19th November. This year United Nations General Assembly designated 19th November as World Toilet Day, urging changes in both behavior and policy on issues ranging from enhancing water management to ending open air defecation. It is estimated that about 2.5 billion people do not have a clean toilet and most of those people live in sub-Saharan Africa and Asia. Yet the humble toilet can be a stepping stone to a healthy life, greater human dignity, freedom, equality between women, men, girls and boys, and finally, a catalyst to the development of communities and countries. Illnesses that are a direct result of bad sanitation affect the quality of life of millions of people around the world, especially children. Diarrhoeal diseases are the second most common cause of death of
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young children in developing countries, killing more than HIV/AIDS, malaria and measles combined, and resulting in 1 death every 20 seconds. Read more

Two

Human

Proteins

Found

to

Affect

How

'Jumping Gene' Gets Around (21st November, 2013)
Using a new method to catch elusive "jumping genes" in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place. Read more

Genomic Variant Associated With Sun Sensitivity
(21st November, 2013)

Researchers have identified a genomic variant strongly associated with sensitivity to the sun, brown hair, blue eyes -- and freckles. In the study of Icelanders the researchers uncovered an intricate pathway involving the interspersed DNA sequence, or non-coding region, of a gene that is among a few dozen that are associated with human pigmentation traits. Read more

Intranasal Insulin improves cognitive function in patients with Type 2 Diabetes
(13th November, 2013)

The link between type 2 diabetes and dementia has become widely recognized. a small proof-of-concept study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) offers promise of a new treatment for this widespread problem. Currently published online in the journal Diabetes Care, the study results show that a single

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dose of intranasal insulin can help improve cognitive function in patients with diabetes. Read more

 Breathalyzer Technology Detects Acetone Levels to Monitor Blood Glucose in Diabetics (13
th

November, 2013)

A novel hand-held, noninvasive monitoring device that uses multilayer nanotechnology to detect acetone has been shown to correlate with blood-glucose levels in the breath of diabetics. This research is being presented at the 2013 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world’s largest pharmaceutical sciences meeting, in San Antonio, Nov. 10–14. Read more

Risk of heart attack, stroke among diabetes patients significantly lower after gastric bypass
(13th November, 2013)

New research from the Cleveland Clinic shows most patients with diabetes and obesity who undergo gastric bypass not only experience remission of their diabetes and lose significant weight, but they also reduce their risk of having a heart attack by 40 percent and their risk for suffering a stroke by 42 percent, over a 10-year time horizon. This study emphasizes that gastric bypass dramatically changes the trajectory of many chronic diseases associated with diabetes and improves multiple cardiovascular risk factors in the long term. Read more

Newly

Identified

Brown

Fat

Stem

Cells

Hold
(21st

Possibilities for Treating Diabetes, Obesity
November, 2013)

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Obesity and diabetes have become a global epidemic leading to severe cardiovascular disease. Researchers at the University of Utah believe their recent identification of brown fat stem cells in adult humans may lead to new treatments for heart and endocrine disorders, according to a new study published in the peer-reviewed journal Stem Cells. Read more

HEALTH AWARENESS

Trachoma-a leading cause of blindness
Trachoma is the leading cause of infectious blindness in the world. It is caused by an obligate intracellular micro-organism called Chlamydia trachomatis. The disease is transmitted through contact with eye and nose discharge of infected people, particularly young children who form the reservoir of infection. It is also spread by flies which have been in contact with the eyes and nose of infected people. Clinical characteristics and morbidity In areas where trachoma is endemic active trachoma is common among preschool-aged children, with prevalence rates which might be as high as 60-90%. The infection becomes less frequent and shorter in duration with increasing age. Infection is usually acquired through living in close proximity to a person with the active disease, and the family is the principal unit for transmission. After years of repeated infection, the inside of the eyelid can become so severely scarred (conjuctival scarring) that it turns inwards and
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the eyelid border causes the eye-lashes to rub against the eyeball (trichiasis) resulting in severe discomfort and pain; this and other alterations of the eye can lead to the scarring of the cornea. Left untreated, this condition leads to the formation of irreversible opacities with resulting visual impairment and blindness typically between the ages 30-40. Visual impairment and blindness results in a worsening of the life experience of individuals and their families, which are normally already among the poorest of the poor. Women are blinded 2 to 3 times more often than men, probably due to their close contact with affected children. Environmental risk factors influencing the transmission of the disease include:
• • • •

poor hygiene; crowded households; water shortage; and inadequate latrines and sanitation facilities. Distribution Trachoma is hyperendemic in many of the poorest and most rural areas of 53 countries of Africa, Asia, Central and South America, Australia and the Middle East. It is responsible for approximately 1% of the world’s blindness and for the visual impairment of about 2.2 million people, of whom 1.2 million are irreversibly blind. Overall, Africa remains the most affected continent and the one with the most intensive control efforts. In 2012, 45 million people were
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treated with antibiotics and 155 thousand cases of trichiasis )were operated in 29 endemic countries of WHO’sAfrica Region. A number of countries have reported achieving intervention goals, which signify the end of the campaign to trachoma elimination and the move to post-endemic surveillance. These countries are: The Gambia, Ghana, Iran, Morocco, Myanmar, Oman and Viet Nam. Last year the United Kingdom’s Department for International Development provided funding to a project aiming to complete the mapping of trachoma endemic areas by 2015. The Australian Government Overseas Aid Programme is funding the elimination of blinding trachoma in the South East Asia Region. Economic impact The burden of trachoma on affected individuals and communities is enormous. The economic cost in terms of lost productivity is estimated at between US$2.9 and US$ 5.3 billion annually, increasing to US$ 8 billion when trichiasis is included. Prevention and control Control programmes in endemic countries are being implemented through the WHO recommended SAFE strategy. This consists of:

• •

surgery to treat the blinding stage of the disease (trachomatous trichiasis or TT); antibiotics to treat infection from chlamydia trachomatis; facial cleanliness, to educate the at risk population on the preventive measures; and environmental improvements, such as providing access to safe water and improved sanitation.
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Most endemic countries have agreed to accelerate the implementation of this strategy to achieve their respective elimination targets, all within the year 2020. Data reported to WHO by Member States in 2012 shows that about 45 million people in endemic communities were treated with antibiotics to eliminate trachoma. the number of people who are reported as receiving surgery for trichiasis is in the order of 169 thousands, the highest recorded so far. Elimination efforts need to continue to satisfy the target set by the World Health Assembly resolution (WHA 51.11), including the cooperation of other health sectors such as sanitation sector and socio economic development sector, in order to achieve the goal of GET2020.

Some Facts of Diabetes
About 347 million people worldwide have diabetes. There is an emerging global epidemic of diabetes that can be traced back to rapid increases in overweight, obesity and physical inactivity. Diabetes is predicted to become the seventh leading cause of death in the world by the year 2030. Total deaths from diabetes are projected to rise by more than 50% in the next 10 years.

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There are two major forms of diabetes. Type 1 diabetes is characterized by a lack of insulin production and type 2 diabetes results from the body's ineffective use of insulin. A third type of diabetes is gestational diabetes. This type is characterized by hyperglycaemia, or raised blood sugar, which has first appeared or been recognized during pregnancy. Type 2 diabetes is much more common than type 1 diabetes. Type 2 accounts for around 90% of all diabetes worldwide. Reports of type 2 diabetes in children – previously rare – have increased worldwide. In some countries, it accounts for almost half of newly diagnosed cases in children and adolescents. Cardiovascular disease is responsible for between 50% and 80% of deaths in people with diabetes. Diabetes has become one of the major causes of premature illness and death in most countries, mainly through the increased risk of cardiovascular disease (CVD). In 2004, an estimated 3.4 million people died from consequences of high fasting blood sugar. 80% of diabetes deaths occur in low- and middle-income countries. In developed countries most people with diabetes are above the age of retirement, whereas in developing countries those most frequently affected are aged between 35 and 64.

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Diabetes is a leading cause of blindness, amputation and kidney failure. Lack of awareness about diabetes, combined with insufficient access to health services and essential medicines, can lead to complications such as blindness, amputation and kidney failure. Type 2 diabetes can be prevented. Thirty minutes of moderate-intensity physical activity on most days and a healthy diet can drastically reduce the risk of developing type 2 diabetes. Type 1 diabetes cannot be prevented. (Based on WHO database)

DISEASE OUTBREAK NEWS

Wild poliovirus in Cameroon (21st November,2013)
Wild poliovirus type 1 (WPV1) has been confirmed in Cameroon, the first wild poliovirus in the country since 2009. Wild poliovirus was isolated from two acute flaccid paralysis (AFP) cases from West Region. The patients developed paralysis on 1 October and 19 October 2013. Genetic sequencing indicates that these viruses are linked to wild poliovirus last detected in Chad in 2011. Read more

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FORTHCOMING EVENTS

 The 2nd Pharm. Tech IAPST International Conference on "New insights into
diseases and recent therapeutic approaches" from 17th to 19th January 2014 in Kolkata, India. Read more

DRUGS UPDATES

 FDA approves Nexavar to treat type of thyroid cancer
(22nd November, 2013)

The U.S. Food and Drug Administration today expanded the approved uses of Nexavar (sorafenib) to treat late-stage (metastatic) differentiated thyroid cancer. Read more

CAMPUS NEWS  B.Pharm 3rd year won the GNIPST Football Champions trophy,
2013. B.Pharm 3rd year won the final match 1-0 against B.Pharm 2nd year. Deep Chakraborty was the only scorer of the final.

 Students of GNIPST organized pre puja celebration programme,
‘Saaranya’ on 7th October, 2013 in college Auditorium.

 GNIPST organized a garment distribution programme on 28th
September, 2013 at Dakshineswar Kali Temple and Adyapith, Kolkata. On this remarkable event about hundred people have
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received garments. More than hundred students and most of the faculties participated on that day with lot of enthusiasm.

GNIPST celebrated World Heart Day (29th September) and
Pharmacist’s Day(25th September) on 25th and 26th September, 2013 in GNIPST Auditorium. A seminar on ‘Violence against woman’ and ‘female foeticide’ was held on GNIPST Auditorium on 25th September organized by JABALA Action Research Organization. On 26th September an intra-college Oral and Poster presentation competition related to World Pharmacist’s day and Heart day was held in GNIPST. Ms. Purbali Chakraborty of B.Pharm 4th year won the first prize in Oral Presentation. The winner of Poster presentation was the group of Ms. Utsa Sinha, Mr. Koushik Saha and Mr. Niladri Banerjee (B.Pharm 4th year). A good number of students have participated in both the competition with their valuable views.

STUDENTS’ SECTION
 WHO CAN ANS WER FIRS T????  Which Indian won the Dan David prize along

with R.Langer and G. Whitesides in 2005?
 Which prize is given in the field of past, present & future?
A) Honey B)Human insulin
Answer of Previous Issue’s Questions:

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Identify the personality

Answer of Previous Issue’s Image:

Frederick Banting and Charles Best, discoverer of insulin

Solve the Puzzle
9 4 5
15 25 ? 12 16 15 20 180 80 a)

125 b) 75 c) 20 d) 25

Answer of Previous Issue’s Puzzle:
HGSOT

 Send your thoughts/ Quiz/Puzzles/games/writeups or any other contributions for Students’ Section& answers of this Section atgnipstbulletin@gmail.com

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EDITOR’S NOTE I am proud to publish the 3rd issue of 30th Volume of GNIPST BULLETIN. GNIPST BULLETIN now connected globally through facebook account ‘GNIPST bulletin’ I want to convey my thanks to all the GNIPST members and the readers for their valuable comments, encouragement and supports. I am thankful to Dr. Abhijit Sengupta, Director of GNIPST for his valuable advice and encouragement. Special thanks to Dr. Prerona Saha and Mr. Debabrata Ghosh Dastidar for their kind co-operation and technical supports. I am thankful to Mr. Subha Bhattacharjee for his contribution to solve the puzzle section .An important part of the improvement of the bulletin is the contribution of the readers. You are invited to send in your write ups, notes, critiques or any kind of contribution for the forthcoming special and regular issue.

ARCHIVE

Teacher’s day was celebrated on 5th September, 2013 by the students of GNIPST in GNIPST Auditorium. Azalea (exotic flower ) , the fresher welcome programme for
newcomers of GNIPST in the session 2013-14 was held on 8th August in GNIPST Auditorium.  One day seminar cum teachers’ development programme for school teachers on the theme of “Recent Trends of Life Sciences
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in Higher Education” organized by GNIPST held on 29th June, 2013 at GNIPST auditorium. The programme was inaugurated by Prof . Asit Guha, Director of JIS Group, Mr. U.S. Mukherjee, Dy Director of JIS Group and Dr. Abhijit Sengupta, Director cum Principal of GNIPST with lamp lighting. The programme started with an opening song performed by the B.Pharm students of this institute. The seminar consists of a series of lectures, video presentations and poster session. On the pre lunch session 4 lectures were given by Dr. Lopamudra Dutta, Mr. Debabrata Ghosh Dastidar, Ms. Swati Nandy and Ms. Tamalika Chakraborty respectively. On their presentation the speakers enlighten the recent development of Pharmacy, Genetics and Microbiology and their correlation with Life Sciences. On the post lunch session, Ms. Saini Setua and Ms. Sanchari Bhattacharjee explained the recent development and career opportunities in Biotechnology and Hospital Management. The programme was concluded with valedictory session and certificate distribution. About 50 Higher secondary school teachers from different schools of Kolkata and North& South 24 Parganas district of West Bengal participated in this programme. A good interactive session between participants and speakers was observed in the seminar. The seminar was a great success with the effort of faculties, staffs and students of our Institute. It was a unique discussion platform for school teachers and professional of the emerging and newer branches of Life Science.  The following B.Pharm. final year students have qualified, GPAT-2013. We congratulate them all.

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 The general body meeting of APTI, Bengal Branch has been conducted at GNIPST on 15th June, 2012. The program started with a nice presentation by Dr. Pulok Kr. Mukherjee, School of Natural Products, JU on the skill to write a good manuscript for publication in impact journals. It was followed by nearly two hour long discussion among more than thirty participants on different aspects of pharmacy education. Five nonmember participants applied for membership on that very day.  GNIPST is now approved by AICTE and affiliated to WBUT for conducting the two years’ post graduate course (M.Pharm) in PHARMACOLOGY. The approved number of seat is 18.  The number of seats in B.Pharm. has been increased from 60 to 120.  AICTE has sanctioned a release of grant under Research Promotion Scheme (RPS) during the financial year 2012-13to GNIPST as per the details below:
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a. Beneficiary Institution: Guru Nanak Institution of Pharmaceutical Science & Technology. b. Principal Investigator: Dr. LopamudraDutta. c. Grant-in-aid sanctioned:Rs. 16,25000/- only d. Approved duration: 3 years e. Title of the project: Screening and identification of potential medicinal plant of Purulia & Bankura districts of West Bengal with respect to diseases such as diabetes, rheumatism, Jaundice, hypertension and developing biotechnological tools for enhancing bioactive molecules in these plants.

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