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  • Molecular Imaging: F FDG PET and A Whole Lot More

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    1. Molecular imaging techniques are potentially better than RECIST for assessing cancer treatment response because changes in cellular metabolism and growth may occur before tumor shrinkage. 2. Molecular imaging can affect the pharmaceutical industry by allowing some clinical trials to be terminated early, determining if a drug is reaching its target, and resulting in cost savings during drug development. 3. Molecular imaging encompasses various techniques including some nuclear medicine studies and some MRI and ultrasound techniques that generate image contrast based on the targeted molecular process.

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    jnmt_sept2009_approved questions4352435234514756098756788697608769876987680680679857856784567354735634743

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    1. Molecular imaging techniques are potentially better than RECIST for assessing cancer treatment response because changes in cellular metabolism and growth may occur before tumor shrinkage. 2. Molecular imaging can affect the pharmaceutical industry by allowing some clinical trials to be terminated early, determining if a drug is reaching its target, and resulting in cost savings during drug development. 3. Molecular imaging encompasses various techniques including some nuclear medicine studies and some MRI and ultrasound techniques that generate image contrast based on the targeted molecular process.

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    11 views3 pages

    Molecular Imaging: F FDG PET and A Whole Lot More

    Uploaded by

    rseresfer34533373563
    1. Molecular imaging techniques are potentially better than RECIST for assessing cancer treatment response because changes in cellular metabolism and growth may occur before tumor shrinkage. 2. Molecular imaging can affect the pharmaceutical industry by allowing some clinical trials to be terminated early, determining if a drug is reaching its target, and resulting in cost savings during drug development. 3. Molecular imaging encompasses various techniques including some nuclear medicine studies and some MRI and ultrasound techniques that generate image contrast based on the targeted molecular process.

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    of 3

    CONTINUINGEDUCATIONTEST:

    MolecularImaging:
    18
    FFDGPETandaWholeLotMore
    1.WhyaremolecularimagingtechniquespotentiallybetterthantheResponseEvaluation
    CriteriainSolidTumors(RECIST)forassessingtreatmentresponseinclinicalcancer
    trials?
    A.Becausethistechniqueinvolvesbiopsy,andthebiopsysiteiscriticaltotheresults.
    B.BecausetheRECISTtechniqueismoreinvasive.
    C.Becausechangesincellularmetabolismandgrowthmayoccursoonerthantumor
    shrinkage.
    D.Alloftheabove.
    2.Howcanmolecularimagingaffectthepharmaceuticalindustry?
    A.Molecularimagingmaycausesomeclinicaltrialstobeterminatedearly.
    B.Molecularimagingcanbeusedtodeterminewhetheradrugisreachingitstargetearly
    in thedevelopmentprocess.
    C.Molecularimagingcanresultinconsiderablecostsavingsduringdrugdevelopment.
    D.Alloftheabove.
    3.Whichofthefollowingstatementsaboutmolecularimagingiscorrect?
    A.Allnuclearmedicinestudiesfallintothebroadercategoryofmolecularimaging.
    B.SomeMRIandultrasoundtechniquesareconsideredmolecularimagingbecauseof
    themethodbywhichimagecontrastisgenerated.
    C.Imagingwithmicrobubblesisthemostwidelyusedimagingmodalityforpreclinical
    molecularimaging.
    D.Opticalimagingmethodsareandwillbemainlyusedforroutineclinicalimaging.
    4.Whichofthefollowingstatementsaboutmolecularimagingisnotcorrect?
    A.Itisintendedprimarilyforresearch.
    B.Itisusefulformanydifferentdiseases.
    C.Itisaccomplishedthroughavarietyoftechniques.
    D.Itisakeycomponentofpersonalizedmedicine.
    5.Whichofthefollowingisakeyadvantageofbioluminescenceimaging(BLI)over
    fluorescenceimaging?
    A.Ithasahighersensitivity.
    B.BLIcanbeperformedavarietyofwaysusingdifferentproteins,dyes,or quantum
    dots.
    C.Thereisexcellentdepthpenetration.
    D.Isolationormanipulationofluciferaseisnotrequired.
    6.Generallyspeaking,whataresomeoftheadvantagesofopticalimaging?
    A.Lowcost.
    B.Noionizingradiation.
    C.Easeofuse.
    D.Alloftheabove.
    7.Whatisakeycharacteristicofamolecularimagingagent?
    A.Itcanbeusedbymultipleimagingmodalities.
    B.Itcanbeusedtoprovideanatomicinformation.
    C.Ittargetsaspecificmolecularentityorprocess.
    D.Itusesalinkertoseparatethetargetingandsignalingmoieties.
    8.Whichbestdescribesthepotentialuseof 3deoxy3
    18
    Ffluorothymidineasa
    molecularimagingagent?
    A.Toidentifyhypoxictissue.
    B.Forapoptosisimaging.
    C.Toassesscellularproliferation.
    D.Forbrainreceptorimaging.
    9.Apoptosisisbestdescribedas
    A.Excessivecellgrowth.
    B.Programmedcelldeath.
    C.Geneticdamagetocells.
    D.Cellrecoveryfrominjury.
    10.Whyisthereaninterestindevelopingagentstoassessapoptosis?
    A.Becauseitcanbeusedtomeasureresponsetotherapy.
    B.Becauseapoptosisregulationiscloselyassociatedwithnumerousdiseases,including
    myocardialinfarction.
    C.Becausetheconceptofapoptosisisrelativelynew.
    D.Both A andB.
    11.Whichofthefollowingisnotareceptorimagingagent?
    A.
    18
    Ffallypride.
    B.
    111
    IndiethylenetriaminepentaaceticacidDpheoctreotide.
    C.
    18
    FFDG.
    D.
    18
    Ffluoroestrodiol.
    12.Thistypeofmolecularimagingagenthasbeenusedtostudytheeffectsofillegal
    drugsonbrainfunctionanddrugsforthetreatmentofpsychiatricdisorders:
    A.Vascularendothelialgrowthfactor receptortargetedprobes.
    B.Nearinfraredfluorescenceagents.
    C.Neuroreceptortargetedprobes.
    D.Alloftheabove.
    13.Whatare thesomepotentialtargetsofsmartmolecularimagingagents?
    A.Enzymeactivity.
    B.pH.
    C.Metaliongradients.
    D.Anyoftheabove.
    14.Activatableimagingprobeshavebeendevelopedfor
    A.Nuclearmedicine.
    B.MRI.
    C.Opticalimaging.
    D.Both BandC.
    15.Whichofthefollowingstatementsistrue?
    A.Itisnotpossibletoimagemorethanonemolecularprocessatthesametime.
    B.Itispossibletoimagemorethanonemolecularprocessatthesametime.

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