Professional Documents
Culture Documents
Drug Study
Drug Study
of Drug
Action of the
drug
Indicatio
n
Contraindic
ation
Adverse
effect
Nursing
responsibilitie
s
Citicoli
ne
1gm IV
q8
Citicoline is a
complex
organic
molecule
that
functions as
an
intermediate
in the
biosynthesis
of cell
membrane
phospholipid
s. It is also
known as
CDP-choline
or cytidine
diphosphate
choline
(cytidine 5'diphosphoch
oline). CDPcholine
belongs to
the group of
biomolecules
in living
systems
known as
nucleotides
that play
important
roles in
cellular
metabolism.
Cerebro
vascular
disorder
s
includin
g
ischemic
stroke
Parasympat
hetic
hypertonia.
Stomach
Somazine
must not be
administered
along with
medicaments
containing
meclophenox
ate
pain
diarrhea
hypoten
sion
tachycar
dia
bradycar
dia
Name of
Drug
Action of
the drug
Indicatio
n
Contraindic
ation
Adverse
effect
Nursing
responsibilities
Rosuvast
atin 20
mg 1 tab
-Inhibits
HMG-coa
reductase,
the
enzyme
that
catalyzes
the first
step in the
cholesterol
synthesis
pathway,
resulting
in a
decrease
in serum
cholesterol
, serum
ldls and
increases
serum hdls
thus,
lowering
triglycerid
e level
Reductio
n of risk
of MI and
stroke in
patients
with
diabetes
and
those
with
multiple
risk
factors
for CAD.
-With
allergy to
Rosuvastati
n, active
hepatic
disease
and
persistent
elevations
of
transamina
se,
impaired
endocrine
function,
history of
liver
disease
and
alcoholism
Headach
e
-Ensure that
patient has
tried
cholesterol
lowering diet
regimen for 36 months
before
beginning
therapy
-Adjunct
to diet in
treatmen
t of
elevated
cholester
ol level
Flatulen
ce
Abdomin
al pain
Cramps
Constipa
tion
Dyspeps
ia
Heartbur
n
Sinusitis
-Administer
drug without
regard to
meals but at
same time
each day
-Do not
combine with
other HMG-coa
reductase
inhibitors
Name of
Drug
Action of
the drug
Indication
Contraindica
tion
Adverse
effect
Nursing
responsibilities
Carvedito
l
-Alpha- and
betaadrenergic
blocker
Hypertens
ion alone
or with
other oral
drugs,
especially
diuretics
Contraindica
ted with
decompensa
ted heart
failure,
bronchial
asthma,
heart block,
cardiogenic
shock,
hypersensiti
vity to
carvedilol,
pregnancy,
lactation
Dizziness
-Assess history
of heart failure,
bronchial
asthma, heart
block,
cardiogenic
shock,
hypersensitivity
to carvedilol,
pregnancy,
lactation,
hepatic
impairment,
peripheral
vascular
disease,
thyrotoxicosis,
diabetes,
anesthesia, or
major surgery
6.25 mg
OD
Antihypertensi
ve
-Treatment
of mild to
severe
heart
failure of
ischemic
or
cardiomyo
pathic
origin with
digitals,
diuretics,
ACE
inhibitors
-Left
ventricula
r
vertigo
tinnitus
fatigue
emotiona
l
depressio
n
paresthes
ias
sleep
disturban
ces
Bradycari
a
orthostati
c
hyperten
sion
heart
failure
-Assess physical
baseline weight,
skin condition,
neurologic
status, P, BP,
ECG, respiratory
dysfunctio
n after MI
cardiac
arrhythmi
as
pulmonar
y edema
status, LFTs,
renal and
thyroid function
tests, blood and
urine glucose.
-Give with food
to decrease
orthostatic
hypertension
and adverse
effects
-Monitor for
orthostatic
hypotension and
provide safety
precautions
-Monitor
diabetic patient
closely; drug
may mask
hypoglycaemia
or worsen
hyperglycemia