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5 authors, including:
Toshiki Kobayashi
Kenneth Bo Foreman
University of Utah
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Stacy Bamberg
University of Utah
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TBME-00277-2012
I. INTRODUCTION
Manuscript received February 17, 2012. This work was supported in part
by a subcontract from Orthocare Innovations through a National Institutes
of Health, Eunice Kennedy Shriver National Institute of Child Health &
Human, SBIR Phase 1 grant (1R43HD069095-01)
A. M. Howell is with the Dept. of Mechanical Engineering, University of
Utah, Salt Lake City, UT 84121 USA (e-mail: adam.howell@utah.edu).
T Kobayashi is with Orthocare Innovations, Mountlake Terrace, WA
98043 USA (e-mail: tkobayashi@orthocareinnovations.com).
H. A. Hayes and K. B. Foreman are with the Dept. of Physical Therapy,
University of Utah, Salt Lake City, UT 84121 USA (e-mail:
heather.hayes@hsc.utah.edu, bo.foreman@hsc.utah.edu).
S. J. M. Bamberg is with the Dept. of Mechanical Engineering, University
of Utah, Salt Lake City, UT 84121 USA (phone: 801.585.9081, e-mail:
sjm.bamberg@utah.edu).
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TBME-00277-2012
regression analysis to determine GRF, with 5% RMS error
compared to a motion laboratory [30]. Aminian et al. added an
inertial measurement unit to the pedar sensor, and used
non-linear techniques to achieve 4% RMS error in GRF [28].
This paper presents the design and validation of an
instrumented insole with twelve FSRs mounted to a flexible
circuit insole. This work expands upon our previous efforts
with low-cost in-shoe sensors to result in a flexible circuit
insole combined with machine learning techniques to identify
the shape and magnitudes of force and moment curves. Each
FSR was individually calibrated with a load-cell. Control
subjects with no known gait abnormalities and hemiplegic
stroke patients who regularly used an ankle-foot orthosis were
evaluated, with simultaneous data collection in a clinical
motion lab. Training data from the insole and corresponding
motion lab results were used in combination with linear
regression to develop models of each subject's gait. Testing
data for each subject were used to predict the GRF, plus
moments of ankle dorsiflexion and plantarflexion, knee
flexion and extension, and knee abduction and adduction. This
is a significant improvement on past work by moving beyond
estimation of forces and focusing on clinically important
variables such as the continuous GRF and ankle and knee
moments. The low-cost insole and accompanying hardware is
much less expensive than equipment required to support the
commercial insoles. The system described in this paper has
been specifically designed to be affordable for use in the
community and in small clinics.
II. METHODS
A. Hardware
An insole with twelve sensors was designed to fit into the
subjects own shoes, as shown in Fig. 1. The sensors were
FSRs, model 402 (Interlink Electronics, Camarillo, CA), and
are inexpensive, highly durable, and simple to implement with
a voltage divider. FSRs decrease in resistance when an
increase of pressure is applied to its 1.27 cm (0.5 inch)
diameter surface. The FSRs were calibrated using an iLoad
Mini 50 pound miniature load cell (Loadstar Sensors, Inc.,
Fremont, CA). To determine an appropriate layout of the FSRs
on the insole, a 32 sensor insole was built and tested. This 32
sensor insole showed that sensors placed in areas under the
heel, metatarsal-phalangeal joints, great toe, and the lateral
arch provided the most influence in the analysis [31]. These
areas correspond to the known biomechanical areas of loading
in a typical plantar pressure distribution.
A flexible circuit board was designed and fabricated to
facilitate rapid and repeatable construction. Longer copper
pads for several of the heel and toe sensors allowed for the
implementation in two sizes of insoles by allowing the
position of these sensors to be altered along the length of the
insole. The small size was used for sizes mens 5-9 (womens
7-11) and the large size for mens 10-13 (womens 12-14).
The sensors were first soldered to the flexible circuit, and
then attached with the adhesive on the back of the FSR. A
sandwich was constructed with the flexible circuit between
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TBME-00277-2012
mass: 69.26.2 kg, height: 1.70.1 m, shoe sizes: 10, 10.5,
11.5 mens and 7 womens), and all wore shorts during testing
to allow markers for the cameras to be placed directly on the
skin of the legs. Stroke subjects were recruited from the
University Health and Wellness Center. There were four
stroke patients (two male, age: 55.810.9 years, mass:
105.414.6 kg, height: 1.80.2 m, shoe sizes: 10, 13 mens
and 7.5, 8 womens). Characteristics of the participants are
detailed in Table 1. The stroke subjects were permitted to use
the attire they were wearing in the clinic that day for their
comfort, which resulted in all stroke subjects wearing pants;
markers were adhered to the outside of the pants. Only one
stroke subject (H) was able to walk with and without his
ankle-foot orthosis. When using an orthosis, the insole was
inserted between the orthosis and the shoe insole.
Stroke Patients
Control Subjects
TABLE 1
CHARACTERISTICS OF PARTICIPANTS
ID
Shoe
Size
Insole
Size
Orthosis
Total
steps
Test group
sizes
10.5 M
No
3, 3, 2
11.5 M
No
50
17,17,16
10 M
No
39
13,13,13
10 M
No
20
7, 7, 6
10M
No
23
8, 8, 7
7W
No
24
8, 8, 8
Gorth
8W
Yes
2, 2, 2
Horth
10 M
Yes
3, 3, 2
10 M
No
3, 2, 2
Iorth
7.5 W
Yes
10
4, 3, 3
Jorth
13 M
Yes
17
6, 6, 5
%RMS =
D. Analysis
Data from the MAL and the insole were exported for
subsequent analysis in MATLAB (Mathworks, Inc., Natick,
MA) and Excel 2010 (Microsoft, Inc., Redmond, WA). Forces
and moments from the MAL were normalized by dividing by
the bodyweight in N and in kg, respectively. A spline fit was
used to resample the MAL data at the time points
corresponding to the insole data.
A least squares linear regression was used to weight the
sensor forces to match the motion lab data for normalized
GRF and moments. Three moments were analyzed: ankle
dorsiflexion / plantarflexion (d/p) moment, knee flexion /
extension (fl/ex) moment, and knee abduction / adduction
(abd/add) moment. The linear regression model was
implemented in MATLAB to determine the weighting
coefficients and a shifting constant. For example, the GRF was
modeled by:
12
(B F
i=1
insole i
)+ B
13
= FMAL
(1)
RMS
MALmax MALmin
(2)
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TBME-00277-2012
TABLE 2
PERCENT RMS ERROR AND SPEARMAN'S CORRELATION COEFFICIENT FOR FORCE AND MOMENT CURVES OF THE INSOLE COMPARED TO THE MAL
ID
Stroke Patients
Control Subjects
5.7 1.8
0.96 0.02
7.1 3.4
0.98 0.02
10.2 3.2
0.91 0.07
5.1 1.2
0.97 0.01
5.5 1.7
0.96 0.06
13.8 6.3
0.91 0.05
15.4 7.5
0.82 0.10
7.8 3.0
0.95 0.04
7.5 3.4
0.97 0.01
13.9 5.2
0.85 0.07
18.2 6.5
0.84 0.09
4.4 0.8
0.98 0.01
4.1 0.8
0.98 0.01
7.7 3.6
0.95 0.02
18.4 3.4
0.85 0.05
4.5 1.5
0.97 0.01
4.6 1.1
0.98 0.01
9.1 3.3
0.93 0.03
15.4 2.3
0.86 0.03
Overall
5.4 2.0
0.97 0.02
5.9 2.7
0.97 0.03
10.7 5.3
0.89 0.17
16.4 5.7
0.84 0.08
Gorth
9.0 3.4
0.97 0.01
24.7 9.5
0.81 0.05
19.1 13.7
0.61 0.4
Horth
4.1 1.0
0.97 0.02
6.6 2.6
0.95 0.03
11.3 3
0.93 0.03
14.5 4.0
0.89 0.07
6.1 3.3
0.96 0.03
10.6 5.1
0.94 0.03
10.8 3.5
0.90 0.05
20.3 7.7
0.84 0.06
Iorth
8.2 4.9
0.95 0.03
14.9 12.2
0.92 0.06
14.1 6.3
0.89 0.06
22.9 12.5
0.79 0.14
Jorth
5.9 2.9
0.97 0.03
8.6 5.5
0.96 0.05
12.1 5.4
0.94 0.06
13.5 7.4
0.88 0.08
Overall
6.4 3.5
0.96 0.02
9.8 7.2
0.95 0.05
13.7 7.0
0.91 0.07
17.1 9.4
0.82 0.18
The corresponding moments were not available from the processed MAL data for these subjects.
-1.9 6.6
-1.5 13.2
5.2 11.5
8.8 16.1
1.1 3.6
0.3 6.8
-11.2 28.8
-2.7 6.9
-5.5 14.8
0.1 23.7
5.4 49.3
-2.9 4.7
-1.8 3.5
0.8 12.2
-3.9 44.2
-0.1 2.5
0.8 5.2
-2.4 13.8
2.9 21.2
Overall
-1.1 5.3
-1.3 9.9
-1.5 19.8
4.2 32.0
Gorth
3.1 9.5
-34.7 32.4
15.5 19.5
Horth
2.5 2.5
-2.2 9.4
10.5 25.9
9.5 16.5
2.8 6.1
0.4 11.6
8.0 14.8
-7.2 29.7
Stroke Patients
Control Subjects
IV. DISCUSSION
Iorth
4.9 11.2
-6.1 26.1
19.0 18.6
-3.9 41.6
Jorth
1.4 8.2
-3.7 11
3.0 20.3
9.1 21.4
Overall
2.6 7.8
-3.1 14.6
2.9 26.5
5.2 26.4
T-test
P = 0.001
P = 0.402
P = 0.784
P = 0.844
The corresponding moments were not available from the processed MAL
data for these subjects.
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5
MAL
Insole
(a)
Force (N/N)
1
0.8
0.6
0.4
0.2
0
0
0.2
0.1
0.2
0.3
0.4
0.5
Time (seconds)
MAL
Insole
(c)
0.15
0.1
0.05
0
0.05
0.1
0.2
0.3
0.4
0.5
Time (seconds)
1.4
1.2
MAL
Insole
(b)
1
0.8
0.6
0.4
0.2
0
0.2
0.6
1.2
TBME-00277-2012
0.6
0.1
0.2
0.3
0.4
0.5
Time (seconds)
0.6
MAL
Insole
(d)
0.4
0.2
0
0.2
0.4
0.6
0.1
0.2
0.3
0.4
0.5
Time (seconds)
0.6
MAL
Insole
(a)
Force (N/N)
1
0.8
0.6
0.4
0.2
0
0
0.2
0.2
0.4
0.6
Time (seconds)
0.8
MAL
Insole
(c)
0.15
0.1
0.05
0
0.05
0.2
0.4
0.6
Time (seconds)
0.8
1.4
1.2
MAL
Insole
(b)
1
0.8
0.6
0.4
0.2
0
0.2
1.2
Fig. 2. A representative plot from a control subject showing motion analysis lab (MAL) and trained insole results for
a) ground reaction force, b) ankle d/p moment, c) knee abd/add moment and d) knee fl/ex moment.
0.6
0.2
0.4
0.6
Time (seconds)
0.8
MAL
Insole
(d)
0.4
0.2
0
0.2
0.4
0
0.2
0.4
0.6
Time (seconds)
0.8
Fig. 3. A representative plot from a stroke subject showing motion analysis lab (MAL) and trained insole results for a) ground reaction force,
b) ankle d/p moment, c) knee abd/add moment and d) knee fl/ex moment. Note that the y-axis of each subplot matches the y-axis of the corresponding
subplot in Figure 2. The x-axes are within Figure 2 and within Figure 3 are consistent across subplots and are selected to match the step duration.
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TBME-00277-2012
Inspection of the representative plots in Figs. 2c, 2d, 3c, and
3d indicates that the general shape is measured surprisingly
well by the insole for both control subjects and stroke patients.
It is likely that the results can be improved by providing the
system with an input corresponding to motion of the knee. Our
next system will include a triaxial accelerometer and triaxial
gyroscope in the ankle box that is worn on the leg. These
outputs will then be used as additional inputs to investigate
whether improved measurement of knee moments is possible.
Indeed, for all four parameters, the visual shape captured by
the insole generally captures the magnitude and shape of the
four kinetic variables as analyzed by the expensive clinical
motion analysis equipment in the MAL. Differences captured
by the MAL in stroke patients as compared to controls are
similarly evident in insole data, as seen in Figs 3 and 4. The
inexpensive insole can therefore be used to provide a quick
estimation for kinetic gait analysis at the foot and ankle. These
visual plots could be used to guide therapy and rehabilitation.
For instance, the slope to the peak on the ankle d/p moment
(as seen in Fig. 3b) corresponds to how well the subject can
control dorsiflexion and plantarflexion. This information may
be used to determine the appropriate stiffness of an orthosis.
Alternatively, these results could be incorporated into a
smartphone system, e.g. to monitor stroke patients throughout
the day to complement the work of Sazonov et al. in
monitoring the activity of stroke patients [7] or to provide
feedback in real-time for gait modification [13]. The knee
abd/add moment could be used to retrain gait in persons with
knee osteoarthritis and delay knee implant surgery [32].
In addition to generally reduced magnitudes, the stroke
patients had a wider variety of shapes in the GRF and the three
moments. This was compounded by the fact that the reduced
physical abilities of the stroke patients meant that less data
was available for training and testing groups. Future studies
will be designed to allow subjects appropriate rest periods
until a larger number of steps are obtained. That will result in
larger sets of training data that encompass a more of the
various step shapes encountered.
Another interesting finding is that the change in percent
errors of the maximum GRF was statistically significantly
different (P=0.001) between the control subjects and the stroke
subjects. The control subjects' models tended to overestimate
the force (as indicated by the negative errors in Table 3)
whereas the stroke subjects' models tended to underestimate
the force. This may be due to the age of the subjects or to the
changes in gait that accompany stroke.
A few problems were encountered in the course of the
subject testing. A transceiver occasionally failed to complete
data transmission for short periods of around 20 ms, possibly
because the transceiver was temporarily obscured by a limb or
if there was interference from other equipment in the MAL.
When a transmission was not received, the receiver duplicated
the data from the previous time step. This resulted in visible
error in the GRF and ankle moment plots for those time
frames. Subject A's data was re-analyzed with the two trials in
which this occurred excluded from the eight steps collected.
This resulted in insignificant changes (a small increase in
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TBME-00277-2012
with the insole. Future work will include triaxial acclerometers
and gyroscopes to provide additional inputs to the model. We
plan to videotape the lower limbs of subjects to provide a
visual comparison of changing gait. Other models, especially
non-linear ones will be explored. In addition, a large array of
subject data will be obtained to create a large set of training
data to allow non-subject specific models to be developed.
Our goal is to provide as system to study the kinetic aspects of
gait when access to a clinical lab is not available. As indicated
by the representative plots shown in Figs. 2 and 3, the shapes
and magnitudes of the GRF and the three moments are
biomechanically different for stroke patients as compared to
the control subjects. For instance, the shape of the ankle
dorsiflexion / plantarflexion moment in a stroke patient can be
compared to a normal curve to investigate whether the orthosis
that is being used is appropriate for the stroke patient's needs
and capabilities.
ACKNOWLEDGMENT
The authors would like to thank Michael Orendurff, Wayne
Daly, and Teri Chou at Orthocare Innovations for their
assistance in many aspects of this research. We greatly
appreciate all of the study subjects for generously donating
their time and energy to make this research possible. We also
thank Heather McElroy and Sam Wright for their assistance
with data collection.
REFERENCES
[1]
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