Name of Drug

Classificatio
n

Generic name:
Oxal

Penicillin,
Oxacillin Na

Brand name:
Shanxi
Taisheng

Dose,
Frequency
and Route
Dose:
610 mg
Frequency:
Every 6 hours
Route:
IV

Mechanism of
Action
Inhibits cell-wall
synthesis during
microorganism
multiplication;
bacteria resists
penicillin by
producing
penicillinase
enzymes that
convert penicillin
to inactivate
penecillic acids.
Oxacillin resists
these enzymes.

Indication

Contraindication
s

Treatment of
Hypersensitivity to
infections due to penicillin.
Staphylococcus
resistant to
benzyl
penicillin
including tissue
infections and
skin disorders.

Side effects and

Adverse Reactions
Side effects:
Fever
Sore throat
Diarrhea
Nausea and
vomiting
Abdominal
cramps

Nursing Responsibilities

Adverse Reactions:
Allergy
Pseudomembrano
us colitis
Thrombophlebitis

Use cautiously in
patients with other
drug allergy,
especially to
cephalosporin.
Obtain specimen for
culture and sensitivity
tests before first dose.
To prevent vein
irritation, avoid
continuous infusions.
Change site every 48
hours.
Give 1-2 hours before
or 2-3 hours after
meals to prevent
gastric irritation.
Use isotonic saline or
D5W and mix with
recommended volume
for desired strength.
Given by continuous
IV infusion in larger
doses.
For intermittent IV
administration (every
6 hours) reconstitute
with