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Name of Drug

Dosage,
Route &
Frequency

Mechanism
of Action

Indication

Contraindication

Side-Effects

Drug to Drug
Interaction

Nursing
Responsibilities

Classification:

Antibiotic
Cephalosporin

Generic Name:

Ceftriaxone
Sodium

Brand Name:
Rocephin

100mg
IVTT every
12 hours

Bactericid
al:
Inhibits
synthesis
of
bacterial
cell wall
causing
cell
death.

Lowers respiratory
infections caused
by Streptococcus
pneumonia,
Staphylococcus
aureus,
Haemophilus
influenza, E. coli,
Enterobacteraerog
enes.
Intra-abdominal
infections caused
by E.coli,
Klebsiellapneumoni
ae

Contraindicat
ed with
allergy to
cephalosporin
s or
penicillins.
Use cautiously
with renal
failure,
lactation,
pregnancy

CNS: Headache,
dizziness,
lethargy
GI: Nausea,
vomiting,
diarrhea,
anorexia,
pseudomembra
nous colitis
HEMATOLOGIC:
bone marrow
depression
dec. WBC,
platelets, Hct
LOCAL: pain,
inflammation of
IV Site
OTHER:
superinfections,
disulfiram-like
reaction with
alcohol

Increased
neprotoxocit
y with
aminoglycosi
des
Increase
bleeding
effects with
oral
anticoagulan
ts
Disulfiramlike reactions
may occur if
alcohol is
taken

BEFORE:
Do Skin Testing
into the
intradermal area
Protect Drug from
light
Do not mix
ceftriaxone with
other
antimicrobial drug
DURING:
Use a separate
syringe when
giving this drug
Have Vitamin K
available in case
of
hypoprothrombin
emia occurs
AFTER:
Discontinue if
hypersensitivity
occurs
Monitor Blood
levels in patients
taking this drug

Name of Drug

Dosage,
Route &
Frequency

Mechanism
of Action

Indication

Contraindication

Side-Effects

Nursing Responsibilities

Classification:

Anti-pyretic

Generic Name:

Paracetamol

325650mg
q4h up to
a
maximu
m of 1
gram
q6h.

Decreases

Control of pain due

fever by a

to headache,

hypothala

earache,

mia

mic effect

dysmenorrhea,

Hemolytic

leading to

arthralgia,

Anemia

sweating

myalgia,

Neutropenia

and

musculoskeletal

Thrombocytopeni

vasodilatio

pain, arthritis,

immunizations,

Pancytopenia

teething,

Leukopenia

Anemia, Renal
Insufficiency

Tonsillectomy

Minimal GI upset.
Methemoglobine

in adults and
75mg/kg/day in children.
2. Do not take for >5days
for pain in children, 10
days for pain in adults, or
more than 3 days for

Urticaria
CNS stimulation

Reduce fever in
viral or bacterial
infections

1. Do not exceed 4gm/24hr.

Hypoglycemic

fever in adults.
3. Extended-Release tablets
are not to be chewed.
4. Monitor CBC, liver and
renal functions.

coma
Jaundice
Glissitis
Drowsiness
Liver Damage

Name of Drug

Dosage,
Route &

Mechanism
of Action

Indication

Contraindication

Side-Effects

Nursing Responsibilities

Frequency

Classification:

Anti-biotic

Adult

s and

bacterial

teenager

RNA and

s7.5
milligram

Generic Name:

cell wall

s (mg)

synthesis

per

alters

kilogram

Vancomycin

Inhibits

(kg) of

permeabili

body

ty of

weight,

bacterial

or 500
mg,

membrane

injected

s causing

into a

cell wall

vein
every six
hours; or
15 mg

lysis and
cell death

To treat
pseudomembranou
s colitis caused by
clostridium difficile
and enterocolitis
caused by
staphylococci

Hypersensitivi
ty to
vancomycin
or its
components,
hypersensitivi
ty to corn or
corn products
when
vancomycin is
given with
dextrose
solutions

CNS:
chills,depression,
Dizziness,fatigue,

device to measure

nia

accurate doses of oral

Vertigo
CV: Hypotension,
Peripheral edema,
vasculitis
GI: abdominal
pain,
constipation,
Clostridium
diarrhea,
Flatulence,
nausea
and vomiting.
GU:

weight,

Nephotoxicity,

or 1

UTI

into a
vein
every

solution

2. Advise patient to notify


prescriber if no
improvement occurs after
few days

3. Instruct patient to
complete full course of
vancomycin as prescribed

4. Instruct patient to notify


prescriber if she develops
severe or persistent

body

injected

calibrated measuring

Headache,imsom

per kg of

gram,

1. Instruct patient to use a

diarrhea

5. Instruct patient to keep


follow-up appointments
during and after
treatment.

twelve
hours.

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