PATHOLOGY

Burkitts
Lymphoma

CLINICAL SIGNS &

SYMPTOMS
Endemic swelling of the
affected jaw or
other facial
bones,
loosening of
the teeth, and
swelling of the
lymph nodes.

Odontogenic
Abscess

Sporadic
-abdominal
pain, and
sometimes
nausea and
vomiting or
bleeding.
Swelling of
affected area.
Severe,
persistent,
throbbing
toothache that
can radiate to
the jawbone,
neck or ear
Sensitivity to hot
and cold
temperatures
Sensitivity to the

RADIOGRAPHIC
FEATURES
Diffuse
radiolucency
Radiolucent
destruction
of the bone
with ragged,
ill-defined
margins.
Also seen as
a motheaten, poorly
marginated
destruction
of bone

Well-defined
lucency at or
distal to the
root apex,
usually less
than 1 cm
with or
without
surrounding
sclerosis
tooth or

HISTOPATHOLOG
Y
Diffuse
infiltrate of
atypical
lymphoid
cells with
numerous
mitosis and a
prominent
starry-sky
pattern
because of
the presence
of multiple
tingible body
macrophages
.

Area of
suppuration
composed of
PMN
leukocytes,
lymphocytes,
cellular
debris,
necrotic
materials &
bacterial

TREATMENT

Chemotherap
y (Intensive
intravenous)

Drainage
established
either
through an
opening in
the tooth or
by incision
over soft
tissue
swelling at
apex

Diffuse Large
B Cell
Lymphoma

pressure of
chewing or biting
Fever
Swelling in
your face or
cheek
Tender, swollen
lymph nodes
under your jaw
or in your neck
Sudden rush of
foul-smelling and
foul-tasting, salty
fluid in your
mouth and pain
relief if the
abscess ruptures

Swollen lymph
nodes (glands),
Swelling of the
liver or spleen,
which can cause
abdominal
pain, swelling
and
discomfort,
Feeling generally

teeth
involved
often show
signs of
caries
widened
periodontal
ligament
space

Plain film:
Chest
radiography
demonstrate
s a soft
tissue
anterior
mediastinal
mass. (vast
majority of

colonies.
Dilation of
blood vessels
in PDL &
bone marrow
space.

Starry sky
pattern
infrequent
Large
lymphoid
cells showing
abundant
cytoplasm
and nuclei
comparable

Antibiotic
administratio
n (start with
penicillin; if
allergic to
penicillin, do
erythromycin
or
clindamycin)

Root canal
therapy or
extraction of
the tooth
(after the
acute phase
of the
disease is
controlled)
Rituximab
plus CHOP
chemotherap
y (R-CHOP)
(for
approximatel
y 4 months)
Radiation
Stem cell
transplants

unwell with B
symptoms
(fever, night
sweats and
unexplained
weight loss).

patients
have an
anterior
mediastinal
mass)

in size or
larger than
reactive
histiocytes.