Professional Documents
Culture Documents
Increased Protease Activity with Breakdown of Elastin in Connective Tissue of Lungs (Elastases, Cathepsins, etc.)
Destruction of Alveolar Walls & Septa and Loss of Elastic Recoil of Bronchial Walls
(EMPHYSEMA)
Loss of Fibrous & Muscle Tissue A Portion of the Capillary Bed of an Alveolus has been eliminated.
Breakdown of Alveolar Elasticity Alveoli cannot support the Increased Air Volume in the Acinus
airways to keep them open
Change in
Dyspnea on Decreased Tactile Inability of the Alveoli to recoil
Airway Size
Exertion Fremitus on Palpation normally after expanding
Amount of air that can be
expired is diminished
Lungs become Chest X-Ray Crackles & Wheezing Bronchiolar Collapse on Expiration
less Compliant
Air Trapping
Barrel Chest, Hyperresonance
Pulmonary Function Test on Chest Percussion Increased Pulmonary
Inability of the Lungs to Vascular Resistance
Circulate Sufficient Air Overdistended Lungs Hyperinflation of the Alveoli
ECG
Airway Calibration Increased Total Lung Capacity Bullae (air spaces) will be formed Pulmonary Hypertension
is Decreased And Residual Volume adjacent to the Pleura (blebs)
Spontaneous Pneumothorax
LEGEND:
Black Text usual pathway
Square Dotted Line Clinical Manifestations
Gray Text Complications
Dash Dot Line with Diamond Arrow Laboratory & Diagnostic Tests